Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: Variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species

Biochemical Society Transactions

Volumn 36, Issue 3, 2008, Pages 312-315

  Rainbow, Dan B ^a   Esposito, Laura ^a   Howlett, Sarah K ^a   Hunter, Kara M ^a   Todd, John A ^a   Peterson, Laurence B ^b   Wicker, Linda S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Autoimmunity; Interleukin 2 (IL 2); Non obese diabetic mouse (NOD mouse); Tolerance; Type 1 diabetes

Indexed keywords

CELL PROTEIN; GENE PRODUCT; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3;

AUTOIMMUNE DISEASE; CONFERENCE PAPER; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE FUNCTION; GENETIC REGULATION; GENETIC VARIABILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESPONSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL;

ALLELES; ANIMALS; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-2; MICE; MICE, INBRED NOD; SPECIES SPECIFICITY; VARIATION (GENETICS);

MUS;

EID: 45249120203     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360312     Document Type: Conference Paper

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