Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues

International Journal of Pharmaceutics

Volumn 392, Issue 1-2, 2010, Pages 294-303

  Kumar, Ajay ^a   Yellepeddi, Venkata K ^a   Davies, Gareth E ^b   Strychar, Kevin B ^c   Palakurthi, Srinath ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b SOUTH DAKOTA STATE UNIVERSITY   (United States)

^c TEXAS A AND M UNIVERSITY CORPUS CHRISTI   (United States)

Author keywords

Dendriplexes; Endocytosis; Ornithine conjugated PAMAMG4 dendrimers (PAMAMG4 ORN60); PAMAMG4; Transfection efficiency

Indexed keywords

DENDRIMER; ORNITHINE; POLYAMIDOAMINE;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEK293; CHEMICAL MODIFICATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SAFETY; ZETA POTENTIAL;

ANIMALS; CATTLE; CELL LINE; CELL SURVIVAL; DENDRIMERS; DNA; DRUG CARRIERS; GREEN FLUORESCENT PROTEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; ORNITHINE; PARTICLE SIZE; PLASMIDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION;

EID: 77952727316     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.03.054     Document Type: Article

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