P2X1 receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo

American Journal of Physiology - Renal Physiology

Volumn 298, Issue 6, 2010, Pages

  Osmond, David A ^a   Inscho, Edward W ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

DPCPX; Hemodynamics; IP5I; P1 purinoceptors; P2 purinoceptors; PPADS

Indexed keywords

ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; PURINERGIC P2 RECEPTOR; PURINERGIC P2X1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; DOSE RESPONSE; IN VIVO STUDY; KIDNEY BLOOD FLOW; KIDNEY PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SPRAGUE DAWLEY RAT;

EID: 77952697877     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00016.2010     Document Type: Article

References (48)

1. Akbar M, Okajima F, Tomura H, Shimegi S, Kondo Y. A single species of A1 adenosine receptor expressed in Chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release. Mol Pharmacol 45: 1036-1042, 1994.
2. Bell PD, Lapointe JY, Peti-Peterdi J. Macula densa cell signaling. Annu Rev Physiol 65: 481-500, 2003.
3. Bidani AK, Griffin KA, Williamson G, Wang X, Loutzenhiser R. Protective importance of the myogenic response in the renal circulation. Hypertension 54: 393-398, 2009.
4. Bidani AK, Mitchell KD, Schwartz MM, Navar LG, Lewis EJ. Absence of glomerular injury or nephron loss in a normotensive rat remnant kidney model. Kidney Int 38: 28-38, 1990.
5. Brown R, Ollerstam A, Johansson B, Skott O, Gebre-Medhin S, Fredholm B, Persson AE. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol 281: R1362-R1367, 2001.
6. Bruns RF, Fergus JH, Badger EW, Bristol JA, Santay LA, Hartman JD, Hays SJ, Huang CC. Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes. Naunyn Schmiedebergs Arch Pharmacol 335: 59-63, 1987.
7. Chen BC, Lee CM, Lin WW. Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages. Br J Pharmacol 119: 1628-1634, 1996.
8. Cupples WA, Braam B. Assessment of renal autoregulation. Am J Physiol Renal Physiol 292: F1105-F1123, 2007.
9. Damer S, Niebel B, Czeche S, Nickel P, Ardanuy U, Schmalzing G, Rettinger J, Mutschler E, Lambrecht G. NF279: a novel potent and selective antagonist of P2X receptor-mediated responses. Eur J Pharmacol 350: R5-R6, 1998.
10. Eppel GA, Ventura S, Evans RG. Regional vascular responses to ATP and ATP analogs in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids. Br J Pharmacol 149: 523-531, 2006. (Pubitemid 44658513)
11. Feng MG, Navar LG. Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats. Hypertension 50: 744-749, 2007.
12. Griffin KA, Picken M, Bakris GL, Bidani AK. Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model. Hypertension 37: 1268-1272, 2001. (Pubitemid 34163580)
13. Grobben B, Claes P, Roymans D, Esmans EL, Van Onckelen H, Slegers H. Ecto-nucleotide pyrophosphatase modulates the purinoceptor-mediated signal transduction and is inhibited by purinoceptor antagonists. Br J Pharmacol 130: 139-145, 2000. (Pubitemid 30248437)
14. Guan Z, Osmond DA, Inscho EW. Purinoceptors in the kidney. Exp Biol Med (Maywood) 232: 715-726, 2007.
15. Hansen PB, Castrop H, Briggs J, Schnermann J. Adenosine induces vasoconstriction through Gi-dependent activation of phospholipase C in isolated perfused afferent arterioles of mice. J Am Soc Nephrol 14: 2457-2465, 2003. (Pubitemid 37169331)
16. Hashimoto S, Huang Y, Briggs J, Schnermann J. Reduced autoregulatory effectiveness in adenosine 1 receptor-deficient mice. Am J Physiol Renal Physiol 290: F888-F891, 2006. (Pubitemid 43724950)
17. Hoyle CH, Pintor J, Gualix J, Miras-Portugal MT. Antagonism of P2X receptors in guinea pig vas deferens by diinosine pentaphosphate. Eur J Pharmacol 333: R1-R2, 1997. (Pubitemid 27388183)
18. Ibarrola AM, Inscho EW, Vari RC, Navar LG. Influence of adenosine receptor blockade on renal function and renal autoregulation. J Am Soc Nephrol 2: 991-999, 1991.
19. Inscho EW. P2 receptors in regulation of renal microvascular function. Am J Physiol Renal Physiol 280: F927-F944, 2001.
20. Inscho EW, Cook AK, Imig JD, Vial C, Evans RJ. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. J Clin Invest 112: 1895-1905, 2003.
21. Inscho EW, Cook AK, Imig JD, Vial C, Evans RJ. Renal autoregulation in P2X1 knockout mice. Acta Physiol Scand 181: 445-453, 2004.
22. Inscho EW, Cook AK, Navar LG. Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation. Am J Physiol Renal Fluid Electrolyte Physiol 271: F1077-F1085, 1996.
23. Inscho EW, LeBlanc EA, Pham BT, White SM, Imig JD. Purinoceptor-mediated calcium signaling in preglomerular smooth muscle cells. Hypertension 33: 195-200, 1999. (Pubitemid 29065659)
24. Jankowski M, Angielski S, Szczepanska-Konkel M. Dissociation between the effects of P1, P4-diadenosine tetraphosphate (Ap4A) on renal haemodynamics and tubular function in anaesthetized rats. J Physiol Pharmacol 59: 129-137, 2008. (Pubitemid 351520168)
25. Jankowski V, Patzak A, Herget-Rosenthal S, Tran TN, Lai EY, Gunthner T, Buschmann I, Zidek W, Jankowski J. Uridine adenosine tetraphosphate acts as an autocrine hormone affecting glomerular filtration rate. J Mol Med 86: 333-340, 2008.
26. Just A, Arendshorst WJ. A novel mechanism of renal blood flow autoregulation and the autoregulatory role of A1 adenosine receptors in mice. Am J Physiol Renal Physiol 293: F1489-F1500, 2007. (Pubitemid 350085984)
27. King BF, Liu M, Pintor J, Gualix J, Miras-Portugal MT, Burnstock G. Diinosine pentaphosphate (IP5I) is a potent antagonist at recombinant rat P2X1 receptors. Br J Pharmacol 128: 981-988, 1999. (Pubitemid 29512031)
28. Knight RJ, Bowmer CJ, Yates MS. The diuretic action of 8-cyclopentyl-1,3-dipropylxanthine, a selective A1 adenosine receptor antagonist. Br J Pharmacol 109: 271-277, 1993. (Pubitemid 23113833)
29. Kuan CJ, Herzer WA, Jackson EK. Cardiovascular and renal effects of blocking A1 adenosine receptors. J Cardiovasc Pharmacol 21: 822-828, 1993. (Pubitemid 23121883)
30. Kuan CJ, Herzer WA, Jackson EK. An experimental paradigm for investigating the role of endogenous adenosine/A1 receptor interactions in vivo. J Pharmacol Exp Ther 263: 657-662, 1992.
31. Majid DS, Inscho EW, Navar LG. P2 purinoceptor saturation by adenosine triphosphate impairs renal autoregulation in dogs. J Am Soc Nephrol 10: 492-498, 1999.
32. Mitchell KD, Navar LG. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. Am J Physiol Renal Fluid Electrolyte Physiol 264: F458-F466, 1993.
33. Moore LC, Casellas D. Tubuloglomerular feedback dependence of autoregulation in rat juxtamedullary afferent arterioles. Kidney Int 37: 1402-1408, 1990. (Pubitemid 20198020)
34. Munger KA, Jackson EK. Effects of selective A1 receptor blockade on glomerular hemodynamics: involvement of renin-angiotensin system. Am J Physiol Renal Fluid Electrolyte Physiol 267: F783-F790, 1994.
35. Ostchega Y, Yoon SS, Hughes J, Louis T. Hypertension awareness, treatment, and control-continued disparities in adults: United States, 2005-2006. NCHS Data Brief 3: 1-8, 2008.
36. Peti-Peterdi J. Multiphoton imaging of renal tissues in vitro. Am J Physiol Renal Physiol 288: F1079-F1083, 2005. (Pubitemid 40677075)
37. Pollock DM, Arendshorst WJ. Native tubular fluid attenuates ANF-induced inhibition of tubuloglomerular feedback. Am J Physiol Renal Fluid Electrolyte Physiol 258: F189-F198, 1990.
38. Premen AJ, Hall JE, Mizelle HL, Cornell JE. Maintenance of renal autoregulation during infusion of aminophylline or adenosine. Am J Physiol Renal Fluid Electrolyte Physiol 248: F366-F373, 1985.
39. Prosdocimo DA, Douglas DC, Romani AM, O'Neill WC, Dubyak GR. Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells. Am J Physiol Cell Physiol 296: C828-C839, 2009.
40. Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492, 1998.
41. Schnermann J, Weihprecht H, Briggs JP. Inhibition of tubuloglomerular feedback during adenosine1 receptor blockade. Am J Physiol Renal Fluid Electrolyte Physiol 258: F553-F561, 1990.
42. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci USA 98: 9983-9988, 2001.
43. Takenaka T, Harrison-Bernard LM, Inscho EW, Carmines PK, Navar LG. Autoregulation of afferent arteriolar blood flow in juxtamedullary nephrons. Am J Physiol Renal Fluid Electrolyte Physiol 267: F879-F887, 1994.
44. Takenaka T, Inoue T, Kanno Y, Okada H, Hill CE, Suzuki H. Connexins 37 and 40 transduce purinergic signals mediating renal autoregulation. Am J Physiol Regul Integr Comp Physiol 294: R1-R11, 2008.
45. Toma I, Bansal E, Meer EJ, Kang JJ, Vargas SL, Peti-Peterdi J. Connexin 40 and ATP-dependent intercellular calcium wave in renal glomerular endothelial cells. Am J Physiol Regul Integr Comp Physiol 294: R1769-R1776, 2008.
46. White SM, Imig JD, Kim TT, Hauschild BC, Inscho EW. Calcium signaling pathways utilized by P2X receptors in freshly isolated preglomerular MVSMC. Am J Physiol Renal Physiol 280: F1054-F1061, 2001.
47. Ziganshin AU, Hoyle CH, Bo X, Lambrecht G, Mutschler E, Baumert HG, Burnstock G. PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder. Br J Pharmacol 110: 1491-1495, 1993.
48. Zou AP, Nithipatikom K, Li PL, Cowley AW Jr. Role of renal medullary adenosine in the control of blood flow and sodium excretion. Am J Physiol Regul Integr Comp Physiol 276: R790-R798, 1999.