The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expression

Molecular and Cellular Biology

Volumn 30, Issue 11, 2010, Pages 2750-2761

  Park, Jeong Hyeon ^a,b   Sun, Xiao Jian ^a   Roeder, Robert G ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; HISTONE ACETYLTRANSFERASE; HISTONE H2AZ; P400 PROTEIN; PROTEIN P21; TIP60 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACETYLTRANSFERASES; ADENOSINE TRIPHOSPHATASES; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY;

EID: 77952642090     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00804-09     Document Type: Article

References (36)

1. Auger, A., L. Galarneau, M. Altaf, A. Nourani, Y. Doyon, R. T. Utley, D. Cronier, S. Allard, and J. Cote. 2008. Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants. Mol. Cell. Biol. 28:2257-2270.
2. Berns, K., E. M. Hijmans, J. Mullenders, T. R. Brummelkamp, A. Velds, M. Heimerikx, R. M. Kerkhoven, M. Madiredjo, W. Nijkamp, B. Weigelt, R. Agami, W. Ge, G. Cavet, P. S. Linsley, R. L. Beijersbergen, and R. Bernards. 2004. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428:431-437.
3. Cai, Y., J. Jin, L. Florens, S. K. Swanson, T. Kusch, B. Li, J. L. Workman, M. P. Washburn, R. C. Conaway, and J. W. Conaway. 2005. The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J. Biol. Chem. 280:13665-13670.
4. Chan, H. M., M. Narita, S. W. Lowe, and D. M. Livingston. 2005. The p400 E1A-associated protein is a novel component of the p53→p21 senescence pathway. Genes Dev. 19:196-201.
5. Doyon, Y., W. Selleck, W. S. Lane, S. Tan, and J. Cote. 2004. Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol. Cell. Biol. 24:1884-1896.
6. Fazzio, T. G., J. T. Huff, and B. Panning. 2008. An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134:162-174.
7. Frank, S. R., T. Parisi, S. Taubert, P. Fernandez, M. Fuchs, H. M. Chan, D. M. Livingston, and B. Amati. 2003. MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep. 4:575-580.
8. Fuchs, M., J. Gerber, R. Drapkin, S. Sif, T. Ikura, V. Ogryzko, W. S. Lane, Y. Nakatani, and D. M. Livingston. 2001. The p400 complex is an essential E1A transformation target. Cell 106:297-307. (Pubitemid 32772614)
9. Gevry, N., H. M. Chan, L. Laflamme, D. M. Livingston, and L. Gaudreau. 2007. p21 transcription is regulated by differential localization of histone H2A.Z. Genes Dev. 21:1869-1881. (Pubitemid 47204927)
10. Gorrini, C., M. Squatrito, C. Luise, N. Syed, D. Perna, L. Wark, F. Martinato, D. Sardella, A. Verrecchia, S. Bennett, S. Confalonieri, M. Cesaroni, F. Marchesi, M. Gasco, E. Scanziani, M. Capra, S. Mai, P. Nuciforo, T. Crook, J. Lough, and B. Amati. 2007. Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature 448:1063-1067.
11. Gregory, P. D. 2001. Transcription and chromatin converge: lessons from yeast genetics. Curr. Opin. Genet. Dev. 11:142-147.
12. Horn, P. J., and C. L. Peterson. 2002. Chromatin higher order folding - wrapping up transcription. Science 297:1824-1827.
13. Ikura, T., V. V. Ogryzko, M. Grigoriev, R. Groisman, J. Wang, M. Horikoshi, R. Scully, J. Qin, and Y. Nakatani. 2000. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102:463-473.
14. Kundu, T. K., V. B. Palhan, Z. Wang, W. An, P. A. Cole, and R. G. Roeder. 2000. Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. Mol. Cell 6:551-561.
15. Kusch, T., L. Florens, W. H. Macdonald, S. K. Swanson, R. L. Glaser, J. R. Yates III, S. M. Abmayr, M. P. Washburn, and J. L. Workman. 2004. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science 306:2084-2087. (Pubitemid 40007658)
16. Legube, G., L. K. Linares, S. Tyteca, C. Caron, M. Scheffner, M. Chevillard-Briet, and D. Trouche. 2004. Role of the histone acetyl transferase Tip60 in the p53 pathway. J. Biol. Chem. 279:44825-44833.
17. Martinato, F., M. Cesaroni, B. Amati, and E. Guccione. 2008. Analysis of Myc-induced histone modifications on target chromatin. PLoS One 3:e3650.
18. Mattera, L., F. Escaffit, M. J. Pillaire, J. Selves, S. Tyteca, J. S. Hoffmann, P. A. Gourraud, M. Chevillard-Briet, C. Cazaux, and D. Trouche. 2009. The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways. Oncogene 28:1506-1517.
19. McMahon, S. B., H. A. Van Buskirk, K. A. Dugan, T. D. Copeland, and M. D. Cole. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94:363-374.
20. Millar, C. B., F. Xu, K. Zhang, and M. Grunstein. 2006. Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast. Genes Dev. 20:711-722.
21. Mizuguchi, G., X. Shen, J. Landry, W. H. Wu, S. Sen, and C. Wu. 2004. ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303:343-348.
22. Nakano, K., T. Mizuno, Y. Sowa, T. Orita, T. Yoshino, Y. Okuyama, T. Fujita, N. Ohtani-Fujita, Y. Matsukawa, T. Tokino, H. Yamagishi, T. Oka, H. Nomura, and T. Sakai. 1997. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. J. Biol. Chem. 272:22199-22206.
23. Park, J. H., and R. G. Roeder. 2006. GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation. Mol. Cell. Biol. 26:4006-4016.
24. Samuelson, A. V., M. Narita, H. M. Chan, J. Jin, E. de Stanchina, M. E. McCurrach, M. Fuchs, D. M. Livingston, and S. W. Lowe. 2005. p400 is required for E1A to promote apoptosis. J. Biol. Chem. 280:21915-21923.
25. Squatrito, M., C. Gorrini, and B. Amati. 2006. Tip60 in DNA damage response and growth control: many tricks in one HAT. Trends Cell Biol. 16:433-442. (Pubitemid 44293403)
26. Sterner, D. E., X. Wang, M. H. Bloom, G. M. Simon, and S. L. Berger. 2002. The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex. J. Biol. Chem. 277:8178-8186.
27. Sun, Y., X. Jiang, S. Chen, N. Fernandes, and B. D. Price. 2005. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc. Natl. Acad. Sci. U. S. A. 102:13182-13187.
28. Sykes, S. M., H. S. Mellert, M. A. Holbert, K. Li, R. Marmorstein, W. S. Lane, and S. B. McMahon. 2006. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Mol. Cell 24:841-851.
29. Tang, Y., J. Luo, W. Zhang, and W. Gu. 2006. Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol. Cell 24:827-839.
30. Taubert, S., C. Gorrini, S. R. Frank, T. Parisi, M. Fuchs, H. M. Chan, D. M. Livingston, and B. Amati. 2004. E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol. Cell. Biol. 24:4546-4556.
31. Tyteca, S., M. Vandromme, G. Legube, M. Chevillard-Briet, and D. Trouche. 2006. Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression. EMBO J. 25:1680-1689.
32. Wang, G. G., C. D. Allis, and P. Chi. 2007. Chromatin remodeling and cancer, part I: covalent histone modifications. Trends Mol. Med. 13:363-372.
33. Wang, G. G., C. D. Allis, and P. Chi. 2007. Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling. Trends Mol. Med. 13:373-380.
34. Yang, X. J. 2004. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Res. 32:959-976.
35. Yu, J., Y. Li, T. Ishizuka, M. G. Guenther, and M. A. Lazar. 2003. A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation. EMBO J. 22:3403-3410. (Pubitemid 36834870)
36. Zhang, Y., G. LeRoy, H. P. Seelig, W. S. Lane, and D. Reinberg. 1998. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities. Cell 95:279-289. (Pubitemid 28473788)