Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity

Cellular and Molecular Life Sciences

Volumn 67, Issue 11, 2010, Pages 1943-1955

  Tosco, Alessandra ^a   Monti, Maria Chiara ^a   Fontanella, Bianca ^a   Montefusco, Sandro ^a   D'Andrea, Luca ^b   Ziaco, Barbara ^b   Baldantoni, Daniela ^a   Rio, Marie Christine ^c   Marzullo, Liberato ^a  

^a UNIVERSITY OF SALERNO   (Italy)

^b CNR   (Italy)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Cell motility; Copper; Copper binding protein; Gastrointestinal peptides; TFF1; Trefoil factors

Indexed keywords

COPPER; CYSTEINE; GLUTAMIC ACID; INTESTINAL TREFOIL FACTOR; TREFOIL PROTEIN 1; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; TFF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CARBOXY TERMINAL SEQUENCE; CELL MOTILITY; CELL STRAIN HT29; CELL STRAIN MCF 7; CONTROLLED STUDY; DIMERIZATION; FLUORESCENCE SPECTROSCOPY; FLUOROMETRY; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; METAL BINDING; NUCLEOTIDE SEQUENCE; PHOTOCHEMICAL QUENCHING; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; STOMACH CANCER; WOUND HEALING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; CELL MOTION; CHEMISTRY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN MULTIMERIZATION; RAT; SITE DIRECTED MUTAGENESIS; SPECTROFLUOROMETRY;

LOTUS; RATTUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELL LINE; CELL MOVEMENT; COPPER; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; RATS; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR SUPPRESSOR PROTEINS; WOUND HEALING;

EID: 77952577606     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0309-7     Document Type: Article

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