Copper-binding activity of Trefoil factor 1 (TFF1): A new perspective in the study of the multifunctional roles of TFFs

Peptides

Volumn 28, Issue 7, 2007, Pages 1461-1469

  Tosco, Alessandra ^a   Monti, Maria Chiara ^a   Fontanella, Bianca ^a   Rio, Marie Christine ^b   Gomez Paloma, Luigi ^a   Leone, Arturo ^a   Marzullo, Liberato ^a  

^a UNIVERSITY OF SALERNO   (Italy)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Copper biosensor; Copper binding protein; SELDI TOF; TFF1; Trefoil factor

Indexed keywords

COPPER; GASTROINTESTINAL POLYPEPTIDE; MUCIN; TREFOIL FACTOR 1; TREFOIL PEPTIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; METAL BINDING; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; CHROMATOGRAPHY, AFFINITY; COPPER; HUMANS; HYDROGEN-ION CONCENTRATION; MASS SPECTROMETRY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

LOTUS;

EID: 34447650767     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.06.004     Document Type: Article

References (24)

1. Blin, et al. Multi-author review Trefoil factors. Cell Mol Life Sci 62 (2006) 2907-2973
2. Bull P.C., and Cox D.W. Wilson disease and Menkes disease: new handles on heavy-metal transport. Trends Genet 10 (1994) 246-252
3. Chadwick M.P., Westley B.R., and May F.E. Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2 through cysteine 58. Biochem J 327 (1997) 117-123
4. Culotta V.C., Klomp L.V., Strain J., Casareno R.L., Krems B., and Gitlin J.D. The copper chaperone for superoxide dismutase. J Biol Chem 272 (1997) 23469-23472
5. Guy P.A., Anderegg R.J., Lim A., Saderholm M.J., Yan Y., and Erickson B.W. Metal-ion binding and limited proteolysis of betabellin 15D, a designed beta-sandwich protein. J Am Soc Mass Spectrom 10 (1999) 969-974
6. Heck A.J., and van den Heuvel R.H. Investigation of intact protein complexes by mass spectrometry. Mass Spectrom Rev 23 5 (2004) 368-389
7. Kannan R., Tomasetto C., Staub A., Bossenmeyer-Pourié C., Thim L., Nielsen P.F., et al. Human pS2/Trefoil factor 1: production and characterization in Pichia pastoris. Protein Exp Purif 21 (2001) 92-98
8. Kelly S.M., Jess T.J., and Price N.C. How to study proteins by circular dichroism. Biochim Biophys Acta 1751 (2005) 119-139
9. Klomp L.W., Lin S.J., Yuan D.S., Klausner R.D., Culotta V.C., and Gitlin J.D. Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis. J Biol Chem 272 (1997) 9221-9226
10. Lefebvre O., Chenard M.P., Masson R., Linares J., Dierich A., LeMeur M., et al. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 274 (1996) 259-262
11. Marzullo L., Tosco A., Capone R., Andersen H.S., Capasso A., and Leone A. Identification of dietary copper- and iron-regulated genes in rat intestine. Gene 338 (2004) 225-233
12. Masiakowski P., Breathnach R., Bloch J., Gannon F., Krust A., and Chambon P. Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res 10 (1982) 7895-7903
13. Newton J.L., Allen A., Westley B.R., and May F.E.B. The human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomach. Gut 46 (2000) 312-320
14. Orrù S., Dal Piaz F., Casbarra A., Biasol G., De Francesco R., Steinkuler C., et al. Conformational changes in the NS3 protease from hepatitis C virus strain Bk monitored by limited proteolysis and mass spectrometry. Protein Sci 8 (1999) 1445-1454
15. Poshakov V.I., Williams M.A., Gargaro A.R., Frenkiel T.A., Westley B.R., Chadwick M.P., et al. High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein. J Mol Biol 267 (1997) 418-432
16. Prohaska J.R., and Gybina A.A. Intracellular copper transport in mammals. J Nutr 134 (2004) 1003-1006
17. Pufahl R.A., Singer C.P., Peariso K.L., Lin S.J., Schmidt P.J., Fahrni C.J., et al. Metal ion chaperone function of the soluble Cu(I) receptor Atx1. Science 278 (1997) 853-856
18. Puig S., Lee J., Lau M., and Thiele D.J. Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake. J Biol Chem 277 (2002) 26021-26030
19. Rio M.C., Chenard M.P., Wolf C., Marcellin L., Tomasetto C., Lathe R., et al. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. Gastroenterology 100 (1991) 375-379
20. Rubino F.M., Verduci C., Giampiccolo R., Pulvirenti S., Brambilla G., and Colombi A. Characterization of the disulfides of bio-thiols by electrospray ionization and triple-quadrupole tandem mass spectrometry. J Mass Spectrom 39 (2004) 1408-1416
21. Ruchaud-Sparagano M.H., Westley B.R., and May F.E.B. The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa. Cell Mol Life Sci 61 (2004) 1946-1954
22. Tang N., Tornatore P., and Weiberger S.R. Current developments in SELDI affinity technology. Mass Spectrom Rev 23 (2004) 34-44
23. Tosco A., Siciliano R.A., Cacace G., Mazzeo M.F., Capone R., Malorni A., et al. Dietary effects of copper and iron deficiency on rat intestine: a differential display proteome analysis. J Proteom Res 4 (2005) 1781-1788
24. Whittal R.M., Ball H.L., Cohen F.E., Burlingame A.L., Prusiner S.B., and Baldwin M.A. Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Sci 9 (2000) 332-343