Increased TFF1 trefoil protein expression in Opisthorchis viverrini-associated cholangiocarcinoma is important for invasive promotion

Hepatology Research

Volumn 37, Issue 4, 2007, Pages 295-304

  Thuwajit, Peti ^a,b   Chawengrattanachot, Watinee ^a,b,d   Thuwajit, Chanitra ^a,b   Sripa, Banchob ^a,b   May, Felicity E B ^c   Westley, Bruce R ^c   Tepsiri, Nisana N ^a,b   Paupairoj, Anucha ^a,b   Chau in, Siri ^a,b  

^a KHON KAEN UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d MINISTRY OF PUBLIC HEALTH   (Thailand)

Author keywords

Cholangiocarcinoma; Invasion; Opisthorchis viverrini; TFF1; Trefoil

Indexed keywords

MUCIN 5AC; TREFOIL PEPTIDE;

ARTICLE; BILE DUCT CARCINOMA; CANCER CELL CULTURE; CANCER INVASION; CANCER TISSUE; CELL INVASION; CELL STIMULATION; CHEMOKINESIS; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; OPISTHORCHIS VIVERRINI; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 33947723701     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00045.x     Document Type: Article

References (48)

1. Srivatanakul P, Sriplung H, Deerasamee S. Epidemiology of liver cancer: an overview. Asian Pac J Cancer Prev 2004; 5: 118-25.
2. Olnes MJ, Erlich R. A review and update on cholangiocarcinoma. Oncology 2004; 66: 167-79.
3. Shaib YH, Davila JA, McGlynn K et al. Rising incidence of intrahepatic cholangiocarcinoma in the United States: A true increase? J Hepatol 2004; 40: 472-7.
4. Okuda K, Nakanuma Y, Miyazaki M. Cholangiocarcinoma: Recent progress. Part 1: Epidemiology and etiology. J Gastroenterol Hepatol 2002; 17: 1049-55.
5. Ishikawa A, Sasaki M, Ohira S et al. Aberrant expression of CDX2 is closely related to the intestinal metaplasia and MUC2 expression in intraductal papillary neoplasm of the liver in hepatolithiasis. Lab Invest 2004; 84: 629-38.
6. Sasaki M, Nakanuma Y, Kim YS. Characterization of apomucin expression in intrahepatic cholangiocarcinomas and their precursor lesions: An immunohistochemical study. Hepatology 1996; 24: 1074-8.
7. Shibahara H, Tamada S, Higashi M et al. MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type. Hepatology 2004; 39: 220-9.
8. Boonla C, Sripa B, Thuwajit P et al. MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma. World J Gastroenterol 2005; 11: 4939-46.
9. Ruchaud-Sparagano MH, Westley BR, May FEB. The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa. Cell Mol Life Sci 2004; 61: 1946-54.
10. Hoffmann W. Trefoil factors TFF (trefoil factor family) peptide-triggered signals promoting mucosal restitution. Cell Mol Life Sci 2005; 62: 2932-8.
11. Rio MC, Chambon P. The pS2 gene, mRNA, and protein: A potential marker for human breast cancer. Cancer Cells 1990; 2: 269-74.
12. Rio MC, Bellocq JP, Daniel JY et al. Breast cancer-associated pS2 protein: Synthesis and secretion by normal stomach mucosa. Science 1988; 241: 705-8.
13. Piggott NH, Henry JA, May FEB et al. Antipeptide antibodies against the pNR-2 oestrogen-regulated protein of human breast cancer cells and detection of pNR-2 expression in normal tissues by immunohistochemistry. J Pathol 1991; 163: 95-104.
14. dos Santos Silva E, Ulrich M, Doring G et al. Trefoil factor family domain peptides in the human respiratory tract. J Pathol 2000; 190: 133-42.
15. Paulsen FP, Hinz M, Schaudig U et al. TFF peptides in the human efferent tear ducts. Invest Ophthalmol Vis Sci 2002; 43: 3359-64.
16. Sasaki M, Tsuneyama K, Saito T et al. Site-characteristic expression and induction of trefoil factor family 1, 2 and 3 and malignant brain tumor-1 in normal and diseased intrahepatic bile ducts relates to biliary pathophysiology. Liver Int 2004; 24: 29-37.
17. Srivatsa G, Giraud AS, Ulaganathan M et al. Biliary epithelial trefoil peptide expression is increased in biliary diseases. Histopathology 2002; 40: 261-8.
18. Kornprat P, Rehak P, Lemmerer M et al. Analysis of trefoil factor family protein 1 (TFF1, pS2) expression in chronic cholecystitis and gallbladder carcinoma. Virchows Arch 2005; 446: 505-10.
19. Shaoul R, Okada Y, Cutz E et al. Colonic expression of MUC2, MUC5AC, and TFF1 in inflammatory bowel disease in children. J Pediatr Gastroenterol Nutr 2004; 38: 488-93.
20. Hippo Y, Yashiro M, Ishii M et al. Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes. Cancer Res 2001; 61: 889-95.
21. Higashiyama M, Doi O, Kodama K et al. Prognostic significance of pS2 protein expression in pulmonary adenocarcinoma. Eur J Cancer 1994; 30A: 792-7.
22. Wang DG, Liu WH, Lundy FT et al. TFF1 gene expression in human medullary thyroid carcinoma. J Pathol 1998; 184: 408-13.
23. Henry JA, Bennett MK, Piggott NH et al. Expression of the pNR-2/pS2 protein in diverse human epithelial tumors. Br J Cancer 1991; 64: 677-82.
24. Koshiyama M, Yoshida M, Konishi M et al. Expression of pS2 protein in endometrial carcinomas: Correlation with clinicopathologic features and sex steroid receptor status. Int J Cancer 1997; 74: 237-44.
25. Colombel M, Dante R, Bouvier R et al. Differential RNA expression of the pS2 gene in the human benign and malignant prostatic tissue. J Urol 1999; 162: 927-30.
26. Missiaglia E, Blaveri E, Terris B et al. Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis. Int J Cancer 2004; 112: 100-12.
27. Hackel C, Falkenberg B, Gunther T et al. The pS2 protein in colorectal carcinomas and metastases. Pathol Res Pract 1998; 194: 171-6.
28. Sasaki M, Tsuneyama K, Nakanuma Y. Aberrant expression of trefoil factor family 1 in biliary epithelium in hepatolithiasis and cholangiocarcinoma. Lab Invest 2003; 83: 1403-13.
29. Yeh TS, Tseng JH, Chen TC et al. Characterization of intrahepatic cholangiocarcinoma of the intraductal growth-type and its precursor lesions. Hepatology 2005; 42: 657-64.
30. May FEB, Westley BR. Trefoil proteins: Their role in normal and malignant cells. J Pathol 1997; 183: 4-7.
31. Prest SJ, May FEB, Westley BR. The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells. FASEB J 2002; 16: 592-4.
32. Ribieras S, Tomasetto C, Rio MC. The pS2/TFF1 trefoil factor, from basic research to clinical applications. Biochim Biophys Acta 1998; 1378: F61-77.
33. Mikhitarian K, Gillanders WE, Almeida JS et al. An innovative microarray strategy identifies informative molecular markers for the detection of micrometastatic breast cancer. Clin Cancer Res 2005; 11: 3697-704.
34. Sripa B, Leungwattanawanit S, Nitta T et al. Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100). World J Gastroenterol 2005; 11: 3392-7.
35. Thornton DJ, Carlstedt I, Howard M, Devine PL, Price MR, Sheehan JK. Respiratory mucins: Identification of core proteins and glycoforms. Biochem J 1996; 316: 967-75.
36. Albini A. Tumor and endothelial cell invasion of basement membranes, The matrigel chemoinvasion assay as a tool for dissecting molecular mechanisms. Pathol Oncol Res 1998; 4: 230-41.
37. Chadwick MP, Westley BR, May FEB. Homodimerization and hetero-oligomerization of the single domain trefoil protein pNR-2/pS2 through cysteine 58. Biochem J 1997; 327: 117-23.
38. May FEB, Church SJ, Major S et al. The closely related estrogen regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge and distribution of surface charge. Biochemistry 2003; 42: 8250-9.
39. Thim L, Madsen F, Poulsen SS. Effect of trefoil factors on the viscoelastic properties of mucus gels. Eur J Clin Invest 2002; 32: 519-27.
40. Van Seuningen I, Pigny P, Perrais M, Porchet N, Aubert JP. Transcriptional regulation of the 11p15 mucin genes. Towards new biological tools in human therapy, in inflammatory diseases and cancer? Front Biosci 2001; 6: D1216-34.
41. Judd LM, Alderman BM, Howlett M et al. Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130. Gastroenterology 2004; 126: 196-207.
42. Khan ZE, Wang TC, Cui G, Chi AL, Dimaline R. Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. Gastroenterology 2003; 125: 510-21.
43. Hirota M, Awatsuji H, Furukawa Y, Hayashi K. Cytokine regulation of PS2 gene expression in mouse astrocytes. Biochem Mol Biol Int 1994; 33: 515-20.
44. Dossinger V, Kayademir T, Blin N, Gott P. Down-regulation of TFF expression in gastrointestinal cell lines by cytokines and nuclear factors. Cell Physiol Biochem 2002; 12: 197-206.
45. Muller W, Borchard F. pS2 protein in gastric carcinoma and normal gastric mucosa: Association with clincopathological parameters and patient survival. J Pathol 1993; 171: 263-9.
46. Emami S, Rodrigues S, Rodrigue CM et al. Trefoil factor family (TFF) peptides and cancer progression. Peptides 2004; 25: 885-98.
47. Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen. Implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 1986; 83: 2496-500.
48. Narasaka T, Moriya T, Endoh M et al. 17β-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver. Endocr J 2000; 47: 697-705.