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Volumn 44, Issue 2, 2010, Pages 118-128

Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivo

Author keywords

Axon pathfinding; Commissural interneuron; GEF; Growth cone; L1; Rac1; Xenopus

Indexed keywords

CELL ADHESION MOLECULE; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LAMININ; PROTEIN CDC42; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TYROSINE; UNCLASSIFIED DRUG; VAV PROTEIN; VAV2 PROTEIN;

EID: 77952542645     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2010.03.001     Document Type: Article
Times cited : (21)

References (90)
  • 2
    • 0034269240 scopus 로고    scopus 로고
    • Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
    • Aghazadeh B., Lowry W.E., Huang X.Y., Rosen M.K. Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation. Cell 2000, 102:625-633.
    • (2000) Cell , vol.102 , pp. 625-633
    • Aghazadeh, B.1    Lowry, W.E.2    Huang, X.Y.3    Rosen, M.K.4
  • 3
    • 0031852652 scopus 로고    scopus 로고
    • Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons
    • Albertinazzi C., Gilardelli D., Paris S., Longhi R., de Curtis I. Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons. J. Cell Biol. 1998, 142:815-825.
    • (1998) J. Cell Biol. , vol.142 , pp. 815-825
    • Albertinazzi, C.1    Gilardelli, D.2    Paris, S.3    Longhi, R.4    de Curtis, I.5
  • 4
    • 0035708325 scopus 로고    scopus 로고
    • Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF
    • Alsina B., Vu T., Cohen-Cory S. Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF. Nat. Neurosci. 2001, 4:1093-1101.
    • (2001) Nat. Neurosci. , vol.4 , pp. 1093-1101
    • Alsina, B.1    Vu, T.2    Cohen-Cory, S.3
  • 5
    • 27944475226 scopus 로고    scopus 로고
    • Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain
    • Amarasinghe G.K., Rosen M.K. Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. Biochemistry 2005, 44:15257-15268.
    • (2005) Biochemistry , vol.44 , pp. 15257-15268
    • Amarasinghe, G.K.1    Rosen, M.K.2
  • 6
    • 21844468249 scopus 로고    scopus 로고
    • Src regulates distinct pathways for cell volume control through Vav and phospholipase Cgamma
    • Barfod E.T., Moore A.L., Melnick R.F., Lidofsky S.D. Src regulates distinct pathways for cell volume control through Vav and phospholipase Cgamma. J. Biol. Chem. 2005, 280:25548-25557.
    • (2005) J. Biol. Chem. , vol.280 , pp. 25548-25557
    • Barfod, E.T.1    Moore, A.L.2    Melnick, R.F.3    Lidofsky, S.D.4
  • 7
    • 0035913909 scopus 로고    scopus 로고
    • Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway
    • Billuart P., Winter C.G., Maresh A., Zhao X., Luo L. Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway. Cell 2001, 107:195-207.
    • (2001) Cell , vol.107 , pp. 195-207
    • Billuart, P.1    Winter, C.G.2    Maresh, A.3    Zhao, X.4    Luo, L.5
  • 8
    • 67049162113 scopus 로고    scopus 로고
    • Wnt5a mediates nerve growth factor-dependent axonal branching and growth in developing sympathetic neurons
    • Bodmer D., Levine-Wilkinson S., Richmond A., Hirsh S., Kuruvilla R. Wnt5a mediates nerve growth factor-dependent axonal branching and growth in developing sympathetic neurons. J. Neurosci. 2009, 29:7569-7581.
    • (2009) J. Neurosci. , vol.29 , pp. 7569-7581
    • Bodmer, D.1    Levine-Wilkinson, S.2    Richmond, A.3    Hirsh, S.4    Kuruvilla, R.5
  • 9
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch G.M. Biology of the p21-activated kinases. Annu. Rev. Biochem. 2003, 72:743-781.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 10
    • 0033974061 scopus 로고    scopus 로고
    • Regulatory and signaling properties of the Vav family
    • Bustelo X.R. Regulatory and signaling properties of the Vav family. Mol. Cell. Biol. 2000, 20:1461-1477.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1461-1477
    • Bustelo, X.R.1
  • 11
    • 34447310566 scopus 로고    scopus 로고
    • Slit1a inhibits retinal ganglion cell arborization and synaptogenesis via Robo2-dependent and -independent pathways
    • Campbell D.S., Stringham S.A., Timm A., Xiao T., Law M.Y., Baier H., Nonet M.L., Chien C.B. Slit1a inhibits retinal ganglion cell arborization and synaptogenesis via Robo2-dependent and -independent pathways. Neuron 2007, 55:231-245.
    • (2007) Neuron , vol.55 , pp. 231-245
    • Campbell, D.S.1    Stringham, S.A.2    Timm, A.3    Xiao, T.4    Law, M.Y.5    Baier, H.6    Nonet, M.L.7    Chien, C.B.8
  • 12
    • 0033678716 scopus 로고    scopus 로고
    • Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance
    • Castellani V., Chedotal A., Schachner M., Faivre-Sarrailh C., Rougon G. Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron 2000, 27:237-249.
    • (2000) Neuron , vol.27 , pp. 237-249
    • Castellani, V.1    Chedotal, A.2    Schachner, M.3    Faivre-Sarrailh, C.4    Rougon, G.5
  • 13
    • 12144267589 scopus 로고    scopus 로고
    • L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region
    • Cheng L., Itoh K., Lemmon V. L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region. J. Neurosci. 2005, 25:395-403.
    • (2005) J. Neurosci. , vol.25 , pp. 395-403
    • Cheng, L.1    Itoh, K.2    Lemmon, V.3
  • 14
    • 0021287359 scopus 로고
    • Sensory physiology, anatomy and immunohistochemistry of Rohon-Beard neurones in embryos of Xenopus laevis
    • Clarke J.D., Hayes B.P., Hunt S.P., Roberts A. Sensory physiology, anatomy and immunohistochemistry of Rohon-Beard neurones in embryos of Xenopus laevis. J. Physiol. 1984, 348:511-525.
    • (1984) J. Physiol. , vol.348 , pp. 511-525
    • Clarke, J.D.1    Hayes, B.P.2    Hunt, S.P.3    Roberts, A.4
  • 16
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
    • Crespo P., Schuebel K.E., Ostrom A.A., Gutkind J.S., Bustelo X.R. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 1997, 385:169-172.
    • (1997) Nature , vol.385 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 17
  • 18
    • 37149057142 scopus 로고    scopus 로고
    • Functions of Rac GTPases during neuronal development
    • de Curtis I. Functions of Rac GTPases during neuronal development. Dev. Neurosci. 2008, 30:47-58.
    • (2008) Dev. Neurosci. , vol.30 , pp. 47-58
    • de Curtis, I.1
  • 19
    • 1642546629 scopus 로고    scopus 로고
    • Netrin-1 and semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton
    • Dent E.W., Barnes A.M., Tang F., Kalil K. Netrin-1 and semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton. J. Neurosci. 2004, 24:3002-3012.
    • (2004) J. Neurosci. , vol.24 , pp. 3002-3012
    • Dent, E.W.1    Barnes, A.M.2    Tang, F.3    Kalil, K.4
  • 20
    • 0035253071 scopus 로고    scopus 로고
    • Rho GTPases in growth cone guidance
    • Dickson B.J. Rho GTPases in growth cone guidance. Curr. Opin. Neurobiol. 2001, 11:103-110.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 103-110
    • Dickson, B.J.1
  • 22
    • 0033564251 scopus 로고    scopus 로고
    • CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation
    • Fujimoto M., Poe J.C., Jansen P.J., Sato S., Tedder T.F. CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation. J. Immunol. 1999, 162:7088-7094.
    • (1999) J. Immunol. , vol.162 , pp. 7088-7094
    • Fujimoto, M.1    Poe, J.C.2    Jansen, P.J.3    Sato, S.4    Tedder, T.F.5
  • 23
    • 17644396388 scopus 로고    scopus 로고
    • Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes
    • Gao C., Schaefer E., Lakkis M., Blystone S.D. Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes. J. Biol. Chem. 2005, 280:15422-15429.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15422-15429
    • Gao, C.1    Schaefer, E.2    Lakkis, M.3    Blystone, S.D.4
  • 24
    • 1542569573 scopus 로고    scopus 로고
    • Working with Xenopus spinal neurons in live cell culture
    • Gomez T.M., Harrigan D., Henley J., Robles E. Working with Xenopus spinal neurons in live cell culture. Meth. Cell Biol. 2003, 71:129-156.
    • (2003) Meth. Cell Biol. , vol.71 , pp. 129-156
    • Gomez, T.M.1    Harrigan, D.2    Henley, J.3    Robles, E.4
  • 26
    • 0036829005 scopus 로고    scopus 로고
    • BDNF release from single cells elicits local dendritic growth in nearby neurons
    • Horch H., Katz L. BDNF release from single cells elicits local dendritic growth in nearby neurons. Nat. Neurosci. 2002, 5:1177-1184.
    • (2002) Nat. Neurosci. , vol.5 , pp. 1177-1184
    • Horch, H.1    Katz, L.2
  • 27
    • 54549104845 scopus 로고    scopus 로고
    • Crosstalk between small GTPases and polarity proteins in cell polarization
    • Iden S., Collard J.G. Crosstalk between small GTPases and polarity proteins in cell polarization. Nat. Rev. Mol. Cell Biol. 2008, 9:846-859.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 846-859
    • Iden, S.1    Collard, J.G.2
  • 28
    • 0028345206 scopus 로고
    • Developmental regulation of islet-1 mRNA expression during neuronal differentiation in embryonic zebrafish
    • Inoue A., Takahashi M., Hatta K., Hotta Y., Okamoto H. Developmental regulation of islet-1 mRNA expression during neuronal differentiation in embryonic zebrafish. Dev. Dyn. 1994, 199:1-11.
    • (1994) Dev. Dyn. , vol.199 , pp. 1-11
    • Inoue, A.1    Takahashi, M.2    Hatta, K.3    Hotta, Y.4    Okamoto, H.5
  • 29
    • 0019828648 scopus 로고
    • Clonal organization of the central nervous system of the frog. II. Clones stemming from individual blastomeres of the 32- and 64-cell stages
    • Jacobson M., Hirose G. Clonal organization of the central nervous system of the frog. II. Clones stemming from individual blastomeres of the 32- and 64-cell stages. J. Neurosci. 1981, 1:271-284.
    • (1981) J. Neurosci. , vol.1 , pp. 271-284
    • Jacobson, M.1    Hirose, G.2
  • 30
    • 0034997358 scopus 로고    scopus 로고
    • Axon guidance at the midline choice point
    • Kaprielian Z., Runko E., Imondi R. Axon guidance at the midline choice point. Dev. Dyn. 2001, 221:154-181.
    • (2001) Dev. Dyn. , vol.221 , pp. 154-181
    • Kaprielian, Z.1    Runko, E.2    Imondi, R.3
  • 31
    • 0024433697 scopus 로고
    • Vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells
    • Katzav S., Martin-Zanca D., Barbacid M. vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. EMBO J. 1989, 8:2283-2290.
    • (1989) EMBO J. , vol.8 , pp. 2283-2290
    • Katzav, S.1    Martin-Zanca, D.2    Barbacid, M.3
  • 32
    • 14044273991 scopus 로고    scopus 로고
    • Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac
    • Kawakatsu T., Ogita H., Fukuhara T., Fukuyama T., Minami Y., Shimizu K., Takai Y. Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. J. Biol. Chem. 2005, 280:4940-4947.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4940-4947
    • Kawakatsu, T.1    Ogita, H.2    Fukuhara, T.3    Fukuyama, T.4    Minami, Y.5    Shimizu, K.6    Takai, Y.7
  • 34
    • 0031027205 scopus 로고    scopus 로고
    • Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
    • Kozma R., Sarner S., Ahmed S., Lim L. Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol. Cell. Biol. 1997, 17:1201-1211.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1201-1211
    • Kozma, R.1    Sarner, S.2    Ahmed, S.3    Lim, L.4
  • 35
    • 0033018626 scopus 로고    scopus 로고
    • Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction
    • Kranenburg O., Poland M., van Horck F.P., Drechsel D., Hall A., Moolenaar W.H. Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction. Mol. Biol. Cell 1999, 10:1851-1857.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 1851-1857
    • Kranenburg, O.1    Poland, M.2    van Horck, F.P.3    Drechsel, D.4    Hall, A.5    Moolenaar, W.H.6
  • 36
    • 0031795592 scopus 로고    scopus 로고
    • Rac1-dependent actin filament organization in growth cones is necessary for beta1-integrin-mediated advance but not for growth on poly-d-lysine
    • Kuhn T.B., Brown M.D., Bamburg J.R. Rac1-dependent actin filament organization in growth cones is necessary for beta1-integrin-mediated advance but not for growth on poly-d-lysine. J. Neurobiol. 1998, 37:524-540.
    • (1998) J. Neurobiol. , vol.37 , pp. 524-540
    • Kuhn, T.B.1    Brown, M.D.2    Bamburg, J.R.3
  • 37
    • 0034695453 scopus 로고    scopus 로고
    • A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation
    • Kuhne M.R., Ku G., Weiss A. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation. J. Biol. Chem. 2000, 275:2185-2190.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2185-2190
    • Kuhne, M.R.1    Ku, G.2    Weiss, A.3
  • 39
    • 0030658939 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho
    • Leeuwen F.N., Kain H.E., Kammen R.A., Michiels F., Kranenburg O.W., Collard J.G. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J. Cell Biol. 1997, 139:797-807.
    • (1997) J. Cell Biol. , vol.139 , pp. 797-807
    • Leeuwen, F.N.1    Kain, H.E.2    Kammen, R.A.3    Michiels, F.4    Kranenburg, O.W.5    Collard, J.G.6
  • 40
    • 0034006173 scopus 로고    scopus 로고
    • Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo
    • Li Z., Van Aelst L., Cline H.T. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nat. Neurosci. 2000, 3:217-225.
    • (2000) Nat. Neurosci. , vol.3 , pp. 217-225
    • Li, Z.1    Van Aelst, L.2    Cline, H.T.3
  • 41
    • 44849141472 scopus 로고    scopus 로고
    • Internal dynamics control activation and activity of the autoinhibited Vav DH domain
    • Li P., Martins I.R., Amarasinghe G.K., Rosen M.K. Internal dynamics control activation and activity of the autoinhibited Vav DH domain. Nat. Struct. Mol. Biol. 2008, 15:613-618.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 613-618
    • Li, P.1    Martins, I.R.2    Amarasinghe, G.K.3    Rosen, M.K.4
  • 42
    • 0033826334 scopus 로고    scopus 로고
    • Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins
    • Liu B.P., Burridge K. Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. Mol. Cell. Biol. 2000, 20:7160-7169.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7160-7169
    • Liu, B.P.1    Burridge, K.2
  • 43
    • 17844400362 scopus 로고    scopus 로고
    • Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3
    • Llorca O., Arias-Palomo E., Zugaza J.L., Bustelo X.R. Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3. EMBO J. 2005, 24:1330-1340.
    • (2005) EMBO J. , vol.24 , pp. 1330-1340
    • Llorca, O.1    Arias-Palomo, E.2    Zugaza, J.L.3    Bustelo, X.R.4
  • 44
    • 0033571855 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor differentially regulates retinal ganglion cell dendritic and axonal arborization in vivo
    • Lom B., Cohen-Cory S. Brain-derived neurotrophic factor differentially regulates retinal ganglion cell dendritic and axonal arborization in vivo. The Journal of neuroscience: the official journal of the Society for Neuroscience 1999, 19:9928-9938.
    • (1999) The Journal of neuroscience: the official journal of the Society for Neuroscience , vol.19 , pp. 9928-9938
    • Lom, B.1    Cohen-Cory, S.2
  • 45
    • 0037894847 scopus 로고    scopus 로고
    • Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav
    • Lopez-Lago M., Lee H., Cruz C., Movilla N., Bustelo X.R. Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav. Mol. Cell. Biol. 2000, 20:1678-1691.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1678-1691
    • Lopez-Lago, M.1    Lee, H.2    Cruz, C.3    Movilla, N.4    Bustelo, X.R.5
  • 46
    • 0036441201 scopus 로고    scopus 로고
    • Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity
    • Luo L. Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu. Rev. Cell Dev. Biol. 2002, 18:601-635.
    • (2002) Annu. Rev. Cell Dev. Biol. , vol.18 , pp. 601-635
    • Luo, L.1
  • 47
    • 0028086441 scopus 로고
    • Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
    • Luo L., Liao Y.J., Jan L.Y., Jan Y.N. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 1994, 8:1787-1802.
    • (1994) Genes Dev. , vol.8 , pp. 1787-1802
    • Luo, L.1    Liao, Y.J.2    Jan, L.Y.3    Jan, Y.N.4
  • 48
    • 34250837980 scopus 로고    scopus 로고
    • Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons
    • Ma L., Tessier-Lavigne M. Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. J. Neurosci. 2007, 27:6843-6851.
    • (2007) J. Neurosci. , vol.27 , pp. 6843-6851
    • Ma, L.1    Tessier-Lavigne, M.2
  • 49
    • 0035833248 scopus 로고    scopus 로고
    • Vav2 is required for cell spreading
    • Marignani P.A., Carpenter C.L. Vav2 is required for cell spreading. J. Cell Biol. 2001, 154:177-186.
    • (2001) J. Cell Biol. , vol.154 , pp. 177-186
    • Marignani, P.A.1    Carpenter, C.L.2
  • 51
    • 0037169499 scopus 로고    scopus 로고
    • Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth
    • Matsuo N., Hoshino M., Yoshizawa M., Nabeshima Y. Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth. J. Biol. Chem. 2002, 277:2860-2868.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2860-2868
    • Matsuo, N.1    Hoshino, M.2    Yoshizawa, M.3    Nabeshima, Y.4
  • 52
    • 0033610868 scopus 로고    scopus 로고
    • Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells
    • Michel F., Grimaud L., Tuosto L., Acuto O. Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells. J. Biol. Chem. 1998, 273:31932-31938.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31932-31938
    • Michel, F.1    Grimaud, L.2    Tuosto, L.3    Acuto, O.4
  • 54
    • 33745890228 scopus 로고    scopus 로고
    • TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology
    • Miyamoto Y., Yamauchi J., Tanoue A., Wu C., Mobley W.C. TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology. Proc. Natl. Acad. Sci. USA 2006, 103:10444-10449.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10444-10449
    • Miyamoto, Y.1    Yamauchi, J.2    Tanoue, A.3    Wu, C.4    Mobley, W.C.5
  • 55
    • 4444378772 scopus 로고    scopus 로고
    • PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching
    • Miyashita T., Yeo S.Y., Hirate Y., Segawa H., Wada H., Little M.H., Yamada T., Takahashi N., Okamoto H. PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching. Development 2004, 131:3705-3715.
    • (2004) Development , vol.131 , pp. 3705-3715
    • Miyashita, T.1    Yeo, S.Y.2    Hirate, Y.3    Segawa, H.4    Wada, H.5    Little, M.H.6    Yamada, T.7    Takahashi, N.8    Okamoto, H.9
  • 56
    • 29044435780 scopus 로고    scopus 로고
    • Adjacent pioneer commissural interneuron growth cones switch from contact avoidance to axon fasciculation after midline crossing
    • Moon M.S., Gomez T.M. Adjacent pioneer commissural interneuron growth cones switch from contact avoidance to axon fasciculation after midline crossing. Dev. Biol. 2005, 288:474-486.
    • (2005) Dev. Biol. , vol.288 , pp. 474-486
    • Moon, M.S.1    Gomez, T.M.2
  • 58
    • 0032696592 scopus 로고    scopus 로고
    • Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins
    • Movilla N., Bustelo X.R. Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins. Mol. Cell. Biol. 1999, 19:7870-7885.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7870-7885
    • Movilla, N.1    Bustelo, X.R.2
  • 60
    • 0036684178 scopus 로고    scopus 로고
    • Rho family GTPases as key regulators for neuronal network formation
    • Negishi M., Katoh H. Rho family GTPases as key regulators for neuronal network formation. J. Biochem. 2002, 132:157-166.
    • (2002) J. Biochem. , vol.132 , pp. 157-166
    • Negishi, M.1    Katoh, H.2
  • 64
    • 34548264315 scopus 로고    scopus 로고
    • Neurotrophic factors switch between two signaling pathways that trigger axonal growth
    • Paveliev M., Lume M., Velthut A., Phillips M., Arumae U., Saarma M. Neurotrophic factors switch between two signaling pathways that trigger axonal growth. J. Cell Sci. 2007, 120:2507-2516.
    • (2007) J. Cell Sci. , vol.120 , pp. 2507-2516
    • Paveliev, M.1    Lume, M.2    Velthut, A.3    Phillips, M.4    Arumae, U.5    Saarma, M.6
  • 65
    • 64549099929 scopus 로고    scopus 로고
    • Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA
    • Rajasekharan S., Baker K.A., Horn K.E., Jarjour A.A., Antel J.P., Kennedy T.E. Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA. Development 2009, 136:415-426.
    • (2009) Development , vol.136 , pp. 415-426
    • Rajasekharan, S.1    Baker, K.A.2    Horn, K.E.3    Jarjour, A.A.4    Antel, J.P.5    Kennedy, T.E.6
  • 68
    • 0033215982 scopus 로고    scopus 로고
    • The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo
    • Ruchhoeft M.L., Ohnuma S., McNeill L., Holt C.E., Harris W.A. The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo. J. Neurosci. 1999, 19:8454-8463.
    • (1999) J. Neurosci. , vol.19 , pp. 8454-8463
    • Ruchhoeft, M.L.1    Ohnuma, S.2    McNeill, L.3    Holt, C.E.4    Harris, W.A.5
  • 69
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 1999, 147:1009-1022.
    • (1999) J. Cell Biol. , vol.147 , pp. 1009-1022
    • Sander, E.E.1    ten Klooster, J.P.2    van Delft, S.3    van der Kammen, R.A.4    Collard, J.G.5
  • 71
    • 11244255723 scopus 로고    scopus 로고
    • Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling
    • Schmid R.S., Midkiff B.R., Kedar V.P., Maness P.F. Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling. NeuroReport 2004, 15:2791-2794.
    • (2004) NeuroReport , vol.15 , pp. 2791-2794
    • Schmid, R.S.1    Midkiff, B.R.2    Kedar, V.P.3    Maness, P.F.4
  • 72
    • 0036644975 scopus 로고    scopus 로고
    • Guanine nucleotide exchange factors for Rho GTPases: turning on the switch
    • Schmidt A., Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 2002, 16:1587-1609.
    • (2002) Genes Dev. , vol.16 , pp. 1587-1609
    • Schmidt, A.1    Hall, A.2
  • 74
    • 0032538792 scopus 로고    scopus 로고
    • Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2
    • Schuebel K.E., Movilla N., Rosa J.L., Bustelo X.R. Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2. EMBO J. 1998, 17:6608-6621.
    • (1998) EMBO J. , vol.17 , pp. 6608-6621
    • Schuebel, K.E.1    Movilla, N.2    Rosa, J.L.3    Bustelo, X.R.4
  • 75
    • 0141668894 scopus 로고    scopus 로고
    • Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src
    • Servitja J.M., Marinissen M.J., Sodhi A., Bustelo X.R., Gutkind J.S. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src. J. Biol. Chem. 2003, 278:34339-34346.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34339-34346
    • Servitja, J.M.1    Marinissen, M.J.2    Sodhi, A.3    Bustelo, X.R.4    Gutkind, J.S.5
  • 77
    • 0035371408 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 promotes axon branching of cortical neurons by influencing morphology and behavior of the primary growth cone
    • Szebenyi G., Dent E.W., Callaway J.L., Seys C., Lueth H., Kalil K. Fibroblast growth factor-2 promotes axon branching of cortical neurons by influencing morphology and behavior of the primary growth cone. J. Neurosci. 2001, 21:3932-3941.
    • (2001) J. Neurosci. , vol.21 , pp. 3932-3941
    • Szebenyi, G.1    Dent, E.W.2    Callaway, J.L.3    Seys, C.4    Lueth, H.5    Kalil, K.6
  • 80
    • 0020582306 scopus 로고
    • The early development of the primary sensory neurones in an amphibian embryo: a scanning electron microscope study
    • Taylor J.S., Roberts A. The early development of the primary sensory neurones in an amphibian embryo: a scanning electron microscope study. J. Embryol. Exp. Morphol. 1983, 75:49-66.
    • (1983) J. Embryol. Exp. Morphol. , vol.75 , pp. 49-66
    • Taylor, J.S.1    Roberts, A.2
  • 81
    • 0030982564 scopus 로고    scopus 로고
    • Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42
    • Threadgill R., Bobb K., Ghosh A. Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 1997, 19:625-634.
    • (1997) Neuron , vol.19 , pp. 625-634
    • Threadgill, R.1    Bobb, K.2    Ghosh, A.3
  • 82
    • 0036631548 scopus 로고    scopus 로고
    • VAV proteins as signal integrators for multi-subunit immune-recognition receptors
    • Turner M., Billadeau D.D. VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nat. Rev. Immunol. 2002, 2:476-486.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 476-486
    • Turner, M.1    Billadeau, D.D.2
  • 84
    • 0033582915 scopus 로고    scopus 로고
    • Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching
    • Wang K.H., Brose K., Arnott D., Kidd T., Goodman C.S., Henzel W., Tessier-Lavigne M. Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching. Cell 1999, 96:771-784.
    • (1999) Cell , vol.96 , pp. 771-784
    • Wang, K.H.1    Brose, K.2    Arnott, D.3    Kidd, T.4    Goodman, C.S.5    Henzel, W.6    Tessier-Lavigne, M.7
  • 85
    • 32544443281 scopus 로고    scopus 로고
    • Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts
    • Woo S., Gomez T.M. Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. J. Neurosci. 2006, 26:1418-1428.
    • (2006) J. Neurosci. , vol.26 , pp. 1418-1428
    • Woo, S.1    Gomez, T.M.2
  • 86
    • 70449365601 scopus 로고    scopus 로고
    • Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion
    • Woo S., Rowan D.J., Gomez T.M. Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion. J. Neurosci. 2009, 29:13981-13991.
    • (2009) J. Neurosci. , vol.29 , pp. 13981-13991
    • Woo, S.1    Rowan, D.J.2    Gomez, T.M.3
  • 87
    • 12244281807 scopus 로고    scopus 로고
    • Wiring of the brain by a range of guidance cues
    • Yamamoto N., Tamada A., Murakami F. Wiring of the brain by a range of guidance cues. Prog. Neurobiol. 2002, 68:393-407.
    • (2002) Prog. Neurobiol. , vol.68 , pp. 393-407
    • Yamamoto, N.1    Tamada, A.2    Murakami, F.3
  • 88
    • 1942517427 scopus 로고    scopus 로고
    • Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish
    • Yeo S.Y., Miyashita T., Fricke C., Little M.H., Yamada T., Kuwada J.Y., Huh T.L., Chien C.B., Okamoto H. Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish. Mech. Dev. 2004, 121:315-324.
    • (2004) Mech. Dev. , vol.121 , pp. 315-324
    • Yeo, S.Y.1    Miyashita, T.2    Fricke, C.3    Little, M.H.4    Yamada, T.5    Kuwada, J.Y.6    Huh, T.L.7    Chien, C.B.8    Okamoto, H.9
  • 90
    • 35649016091 scopus 로고    scopus 로고
    • Regulation of ephexin1, a guanine nucleotide exchange factor of Rho family GTPases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation
    • Zhang Y., Sawada T., Jing X., Yokote H., Yan X., Sakaguchi K. Regulation of ephexin1, a guanine nucleotide exchange factor of Rho family GTPases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation. J. Biol. Chem. 2007, 282:31103-31112.
    • (2007) J. Biol. Chem. , vol.282 , pp. 31103-31112
    • Zhang, Y.1    Sawada, T.2    Jing, X.3    Yokote, H.4    Yan, X.5    Sakaguchi, K.6


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