Theoretical exploration of the neural bases of behavioural disinhibition, apathy and executive dysfunction in preclinical Alzheimer's disease in people with Down's syndrome: Potential involvement of multiple frontal-subcortical neuronal circuits

Journal of Intellectual Disability Research

Volumn 54, Issue 4, 2010, Pages 320-336

  Ball, S L ^a   Holland, A J ^a   Watson, P C ^b   Huppert, F A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MRC COGNITION AND BRAIN SCIENCES UNIT   (United Kingdom)

Author keywords

Alzheimer's disease; Behavioural change; Dementia; Down's syndrome; Executive function; Frontal lobe

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; AGED; ALZHEIMER DISEASE; APATHY; ARTICLE; BEHAVIOR CHANGE; BEHAVIOR DISORDER; BRAIN CORTEX; COGNITIVE DEFECT; DOWN SYNDROME; FRONTAL LOBE; HUMAN; INTELLECTUAL IMPAIRMENT; INTELLIGENCE; MAJOR CLINICAL STUDY; MEMORY DISORDER; MENTAL PERFORMANCE; MENTAL TASK; NERVE CELL NETWORK; PERSONALITY DISORDER; WORKING MEMORY;

ADULT; AGED; ALZHEIMER DISEASE; BRAIN; CHILD; CHILD BEHAVIOR DISORDERS; COGNITION DISORDERS; COMORBIDITY; DOWN SYNDROME; FEMALE; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; NERVE NET; NEUROPSYCHOLOGICAL TESTS; PSYCHOLOGICAL THEORY; SEVERITY OF ILLNESS INDEX;

EID: 77952487837     PISSN: 09642633     EISSN: 13652788     Source Type: Journal    
DOI: 10.1111/j.1365-2788.2010.01261.x     Document Type: Article

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