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Volumn 293, Issue 2, 2010, Pages 158-166

Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo

Author keywords

Apoptosis; Sunitinib; Synergism; TRAIL

Indexed keywords

FLICE INHIBITORY PROTEIN; PROTEIN MCL 1; SUNITINIB; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; PYRROLE DERIVATIVE;

EID: 77952467667     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.01.005     Document Type: Article
Times cited : (30)

References (36)
  • 2
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumor-necrosis factor superfamily
    • Ashkenazi A. Targeting death and decoy receptors of the tumor-necrosis factor superfamily. Nat. Rev. Cancer 2002, 2:420-430.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 420-430
    • Ashkenazi, A.1
  • 4
    • 0034478111 scopus 로고    scopus 로고
    • Intracellular mechanisms of TRAIL and its role in cancer therapy
    • Srivastava R.K. Intracellular mechanisms of TRAIL and its role in cancer therapy. Mol. Cell. Biol. Res. Commun. 2000, 4:67-75.
    • (2000) Mol. Cell. Biol. Res. Commun. , vol.4 , pp. 67-75
    • Srivastava, R.K.1
  • 5
    • 0035117460 scopus 로고    scopus 로고
    • Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis
    • Seol D.W., Li J., Seol M.H., Park S.Y., Talanian R.V., Billiar T.R. Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis. Cancer Res. 2001, 61:1138-1143.
    • (2001) Cancer Res. , vol.61 , pp. 1138-1143
    • Seol, D.W.1    Li, J.2    Seol, M.H.3    Park, S.Y.4    Talanian, R.V.5    Billiar, T.R.6
  • 6
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: critical control points
    • Danial N.N., Korsmeyer S.J. Cell death: critical control points. Cell 2004, 116:205-219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 7
    • 2942584501 scopus 로고    scopus 로고
    • Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells
    • Rosato R.R., Almenara J.A., Dai Y., Grant S. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. Mol. Cancer Ther. 2003, 2:1273-1284.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 1273-1284
    • Rosato, R.R.1    Almenara, J.A.2    Dai, Y.3    Grant, S.4
  • 8
    • 0036259143 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways
    • Cartee L., Smith R., Dai Y., Rahmani M., Rosato R., Almenara J., Dent P., Grant S. Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways. Mol. Pharmacol. 2002, 61:1313-1321.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 1313-1321
    • Cartee, L.1    Smith, R.2    Dai, Y.3    Rahmani, M.4    Rosato, R.5    Almenara, J.6    Dent, P.7    Grant, S.8
  • 9
    • 2942565827 scopus 로고    scopus 로고
    • Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications
    • Shankar S., Srivastana R.K. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist. Update. 2004, 2:139-156.
    • (2004) Drug Resist. Update. , vol.2 , pp. 139-156
    • Shankar, S.1    Srivastana, R.K.2
  • 10
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • Zhang L., Fang B. Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther. 2005, 12:228-237.
    • (2005) Cancer Gene Ther. , vol.12 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 11
    • 77952669177 scopus 로고    scopus 로고
    • Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells
    • Hori T., Kondo T., Kanamori M., Tabuchi Y., Ogawa R., Zhao Q.L., Ahmed K., Yasuda T., Seki S., Suzuki K., Kimura T. Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells. Cancer Lett. 2009.
    • (2009) Cancer Lett.
    • Hori, T.1    Kondo, T.2    Kanamori, M.3    Tabuchi, Y.4    Ogawa, R.5    Zhao, Q.L.6    Ahmed, K.7    Yasuda, T.8    Seki, S.9    Suzuki, K.10    Kimura, T.11
  • 12
    • 78650874372 scopus 로고    scopus 로고
    • SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
    • Abrams T.J., Lee L.B., Murray L.J., Pryer N.K., Cherrington J.M. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol. Cancer Ther. 2003, 2:471-478.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 471-478
    • Abrams, T.J.1    Lee, L.B.2    Murray, L.J.3    Pryer, N.K.4    Cherrington, J.M.5
  • 16
    • 35148900795 scopus 로고    scopus 로고
    • The Multikinase Inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL downregulation
    • Rosato R.R., Almenara J.A., Coe S., Grant S. The Multikinase Inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL downregulation. Cancer Res. 2007, 67:9490-9500.
    • (2007) Cancer Res. , vol.67 , pp. 9490-9500
    • Rosato, R.R.1    Almenara, J.A.2    Coe, S.3    Grant, S.4
  • 17
    • 33847726589 scopus 로고    scopus 로고
    • Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
    • Shrader M., Pino M.S., Lashinger L., Bar-Eli M., Adam L., Dinney C.P., McConkey D.J. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res. 2007, 67:1430-1435.
    • (2007) Cancer Res. , vol.67 , pp. 1430-1435
    • Shrader, M.1    Pino, M.S.2    Lashinger, L.3    Bar-Eli, M.4    Adam, L.5    Dinney, C.P.6    McConkey, D.J.7
  • 18
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T.C., Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regulat. 1984, 22:27-55.
    • (1984) Adv. Enzyme Regulat. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 19
    • 0019882480 scopus 로고
    • Generalized equations for the analysis of inhibitions of Michaelis-Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors
    • Chou T.C., Talalay P. Generalized equations for the analysis of inhibitions of Michaelis-Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors. Eur. J. Biochem. 1981, 115:207-216.
    • (1981) Eur. J. Biochem. , vol.115 , pp. 207-216
    • Chou, T.C.1    Talalay, P.2
  • 20
    • 34548814971 scopus 로고    scopus 로고
    • Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo
    • Kang M.H., Kang Y.H., Szymanska B., Wilczynska-Kalak U., Sheard M.A., Harned T.M., Lock R.B., Reynolds C.P. Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo. Blood 2007, 110:2057-2066.
    • (2007) Blood , vol.110 , pp. 2057-2066
    • Kang, M.H.1    Kang, Y.H.2    Szymanska, B.3    Wilczynska-Kalak, U.4    Sheard, M.A.5    Harned, T.M.6    Lock, R.B.7    Reynolds, C.P.8
  • 21
    • 53649109665 scopus 로고    scopus 로고
    • A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma
    • Ndozangue-Touriguine O., Sebbagh M., Mérino D., Micheau O., Bertoglio J., Bréard J. A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma. Oncogene 2008, 27:6012-6022.
    • (2008) Oncogene , vol.27 , pp. 6012-6022
    • Ndozangue-Touriguine, O.1    Sebbagh, M.2    Mérino, D.3    Micheau, O.4    Bertoglio, J.5    Bréard, J.6
  • 23
    • 33344476184 scopus 로고    scopus 로고
    • CFLIP regulation of lymphocyte activation and development
    • Budd R.C., Yeh W.C., Tschopp J. cFLIP regulation of lymphocyte activation and development. Nat. Rev. Immunol. 2006, 6:196-204.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 196-204
    • Budd, R.C.1    Yeh, W.C.2    Tschopp, J.3
  • 24
  • 25
    • 35948950248 scopus 로고    scopus 로고
    • The inhibitor of apoptosis proteins as therapeutic targets in cancer
    • Fairbrother W.J., Vucic D. The inhibitor of apoptosis proteins as therapeutic targets in cancer. Clin. Cancer Res. 2007, 13:5995-6000.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5995-6000
    • Fairbrother, W.J.1    Vucic, D.2
  • 26
    • 54249159248 scopus 로고    scopus 로고
    • Targeting XIAP Bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
    • Vogler M., Walczak H., Stadel D., Haas T.L., Genze F., Jovanovic M., Gschwend J.E., Simmet T., Debatin K.M., Fulda S. Targeting XIAP Bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 2008, 68:7956-7965.
    • (2008) Cancer Res. , vol.68 , pp. 7956-7965
    • Vogler, M.1    Walczak, H.2    Stadel, D.3    Haas, T.L.4    Genze, F.5    Jovanovic, M.6    Gschwend, J.E.7    Simmet, T.8    Debatin, K.M.9    Fulda, S.10
  • 27
    • 85042587668 scopus 로고    scopus 로고
    • Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
    • Fakler M., Loeder S., Vogler M., Schneider K., Jeremias I., Debatin K.M., Fulda S. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood 2009, 113:1710-1722.
    • (2009) Blood , vol.113 , pp. 1710-1722
    • Fakler, M.1    Loeder, S.2    Vogler, M.3    Schneider, K.4    Jeremias, I.5    Debatin, K.M.6    Fulda, S.7
  • 29
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams J.M., Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007, 26:1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 31
    • 23844471512 scopus 로고    scopus 로고
    • Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1
    • Wirth T., Kühnel l F., Fleischmann-Mundt B., Woller N., Djojosubroto M., Rudolph K.L., Manns M., Zender L., Kubicka S. Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1. Cancer Res. 2005, 65:7393-7402.
    • (2005) Cancer Res. , vol.65 , pp. 7393-7402
    • Wirth, T.1    Kühnel l, F.2    Fleischmann-Mundt, B.3    Woller, N.4    Djojosubroto, M.5    Rudolph, K.L.6    Manns, M.7    Zender, L.8    Kubicka, S.9
  • 34
    • 49849097056 scopus 로고    scopus 로고
    • Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells
    • Wang X., Chen W., Zeng W., Bai L., Tesfaigzi Y., Belinsky S.A., Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol. Cancer Ther. 2008, 7:1156-1163.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 1156-1163
    • Wang, X.1    Chen, W.2    Zeng, W.3    Bai, L.4    Tesfaigzi, Y.5    Belinsky, S.A.6    Lin, Y.7
  • 35
    • 59149087882 scopus 로고    scopus 로고
    • Suppression of cFLIP by Lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells
    • Murtaza I., Saleem M., Adhami V.M., Hafeez B.B., Mukhtar H. Suppression of cFLIP by Lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells. Cancer Res. 2009, 69:1156-1165.
    • (2009) Cancer Res. , vol.69 , pp. 1156-1165
    • Murtaza, I.1    Saleem, M.2    Adhami, V.M.3    Hafeez, B.B.4    Mukhtar, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.