Antiproliferative activity of derivatives of ouabain, digoxin and proscillaridin A in human MCF-7 and MDA-MB-231 breast cancer cells

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 6, 2008, Pages 1131-1140

  Winnicka, Katarzyna ^a   Bielawski, Krzysztof ^a   Bielawska, Anna ^a   Surazyński, Arkadiusz ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Breast cancer cell; Cardiac glycoside; Cytotoxicity; DNA topoisomerase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 [14 HYDROXY 10,13 DIMETHYL 3 (3,4,5 TRIHYDROXY 6 METHYLTETRAHYDRO 2H PYRAN 2 YLOXY) 2,3,6,7,8,9,10,11,12,13,14,15,16,17 TETRADECAHYDRO 1H CYCLOPENTA[A]PHENANTHREN 17 YL] 5 OXOPENT 2 ENOIC ACID; 4 HYDROXY 3 [1,5,11,14 TETRAHYDROXY 10 (HYDROXYMETHYL) 13 METHYL 3 (3,4,5 TRIHYDROXY 6 METHYLTETRAHYDRO 2H PYRAN 2 YLOXY)HEXADECAHYDRO 1H CYCLOPENTA[A]PHENANTHREN 17 YL]BUT 2 ENOIC ACID; CALCIUM ION; CARBOXYLIC ACID; CASPASE 3; DIGOXIN; DIGOXIN DERIVATE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; LACTONE; OUABAIN; PROSCILLARIDIN; THYMIDINE;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE;

BLOTTING, WESTERN; CALCIUM; CARBOHYDRATE SEQUENCE; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DIGOXIN; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA, NEOPLASM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; INDICATORS AND REAGENTS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; OUABAIN; PROSCILLARIDIN;

EID: 45749146656     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1131     Document Type: Article

References (43)

1. Mijatovic T., van Quaquebeke E., Delest B., Debeir O., Darro F., Kiss R., Biochim. Biophys. Acta, 1776, 32-57 (2007).
2. Stenkvist B., Bengtsson E., Eklund G., Eriksson O., Holmquist J., Nordin B., Westman-Naeser S., Anal. Quant. Cytol., 2, 49-54 (1980).
3. Stenkvist B., Bengtsson E., Dahlqvist B., Eriksson O., Jarkrans T., Nordin B., N. Engl. J. Med., 306, 484 (1982).
4. Stenkvist B., Oncol. Rep., 6, 493-496 (1999).
5. Masuda Y., Kawazoe N., Nakajo S., Yoshida T., Kuroiwa Y., Nakaya K., Leuk. Res., 19, 549-556 (1995).
6. Hashimoto S., Jing Y., Kawazoe N., Masuda Y., Nakajo S., Yoshida T., Kuroiwa Y., Nakaya K., Leuk. Res., 21, 875-883 (1997).
7. Haux J., Med. Hypotheses, 53, 543-548 (1999).
8. Sen C. K., Sashwati R., Packer L., Cell Death Differ., 6, 481-491 (1999).
9. Watabe M., Masuda Y., Nakajo S., Yoshida T., Kuroiwa Y., Nakaya K., J. Biol. Chem., 271, 14067-14073 (1996).
10. Lin H., Juang J. L., Wang P. S., J. Biol. Chem., 279, 29302-29307 (2004).
11. Wertz I. E., Dixit V. M., J. Biol. Chem., 275, 11470-11477 (2000).
12. Huang Y. T., Chueh S. C., Teng C. M., Guh J. H., Biochem. Pharmacol., 67, 727-733 (2004).
13. McConkey D. J., Lin Y., Nutt L. K., Ozel H. Z., Newman R. A., Cancer Res., 60, 3807-3812 (2000).
14. Yeh J. Y., Huang W. J., Kan S. F., Wang P. S., Prostate, 54, 112-124 (2003).
15. Newman R. A., Yang P., Hittelman W. N., Lu T., Ho D. H., Ni D., Chan D., Vijjeswarapu M., Cartwright C., Dixon S., Felix E., Addington C., J. Exp. Ther. Oncol., 5, 167-181 (2006).
16. Frese S., Frese-Schaper M., Andres A. C., Miescher D., Zumkehr B., Schmid R. A., Cancer Res., 66, 5867-5874 (2006).
17. Förster W., "Die Herzwirksamen Glykoside. Herkunft, Chemie und Grundlagen ihrer pharmakologischen und klinischen Wirkung," ed. by Baumgarten G., Förster W., VEB Georg Thieme, Leipzig, 1963, pp. 199-233.
18. Goto A., Yamada K., Yagi N., Yoshioka M., Sugimoto T., Pharmacol. Rev., 44, 377-399 (1992).
19. Van Quaquebeke E., Simon G., Andre A., Dewelle J., El Yazidi M., Bruyneel F., Tuti J., Nacoulma O., Guissou P., Decaestecker C., Braekman J. C., Kiss R., Darro F., J. Med. Chem., 48, 849-856 (2005).
20. Carmichael J., Degraff W., Gazdar A., Minna J., Mitchell J., Cancer Res., 47, 936-942 (1987).
21. Martin S. J., Reutelingsperger C. P. M., McGahon A. J., Rader J. A., van Schie R. C., J. Exp. Med., 182, 1545-1556 (1995).
22. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C., J. Immunol. Methods, 184, 39-51 (1995).
23. Duke R. C., Cohen J. J., Curr. Protoc. Immunol., 17, 1-16 (1992).
24. Laemmli U. K., Nature (London), 227, 680-685 (1970).
25. Grynkiewicz G., Poenie M., Tsien R. Y., J. Biol. Chem., 260, 3440-3450 (1985).
26. Bielawski K., Winnicka K., Bielawska A., Biol. Pharm. Bull., 29, 1493-1497 (2006).
27. Winnicka K., Bielawski K., Bielawska A., Miltyk W., Arch. Pharm. Res., 30, 1216-1224 (2007).
28. Villa P., Kaufmann S. H., Earnshaw W. C., Trends Biochem. Sci., 22, 388-393 (1997).
29. Janicke R. U., Sprengart M. L., Wati M. R., Porter A. G., J. Biol. Chem., 273, 9357-9360 (1998).
30. Akimova O. A., Bagrov A. Y., Lopina O. D., Kamernitsky A. V., Tremblay J., Hamet P., Orlov S. N., J. Biol. Chem., 280, 832-839 (2005).
31. Furuya Y., Lundmo P., Short A. D., Gill D. L., Isaacs J. T., Cancer Res., 54, 6167-6175 (1994).
32. Chen J. Q., Contreras R. G., Wang R., Fernandez S. V., Shoshani L., Russo I. H., Cereijido M., Russo J., Breast Cancer Res. Treat., 96, 1-15 (2006).
33. Manunta P., Hamilton B. P., Hamlyn J. M., Hypertension, 37, 472-477 (2001).
34. Xie Z., Askari A., Eur. J. Biochem., 269, 2434-2439 (2002).
35. Cassady J. M., Suffness M., "Anti Cancer Agents Based on Natural Products Models," ed. by Cassady J. M., Douros J. D., Academic Press, New York, 1980, pp. 201-269.
36. Trump B. F., Berezesky I. K., FASEB J., 9, 219-228 (1995).
37. Daniel D., Susal C., Kopp B., Opelz G., Terness P., Int. Immunopharmacol., 3, 1791-1801 (2003).
38. Manna S. K., Sah N. K., Newman R. A., Cisneros A., Aggarwal B. B., Cancer Res., 60, 3838-3847 (2000).
39. Smith J. A., Madden T., Vijjeswarapu M., Newman R. A., Biochem. Pharmacol., 62, 469-472 (2001).
40. Aydemir-Koksoy A., Allen J. C., Am. J. Physiol. Heart Circ. Physiol., 280, H1869-H1874 (2001).
41. Verheye-Dua F., Bohm L., Radiat. Oncol. Investig., 6, 109-119 (1998).
42. Johnson C. A., Padget K., Austin C. A., Turner B. M., J. Biol. Chem., 276, 4539-4542 (2001).
43. Cardellini E., Durban E., Biochem. J., 291, 303-307 (1993).