Cardenolides from Pergularia tomentosa display cytotoxic activity resulting from their potent inhibition of Na+/K+-ATPase

Journal of Natural Products

Volumn 72, Issue 6, 2009, Pages 1087-1091

  Piacente, Sonia ^a   Masullo, Milena ^a   De Nève, Nancy ^b   Dewelle, Janique ^b   Hamed, Arafa ^c   Kiss, Robert ^d   Mijatovic, Tatjana ^b,d  

^a UNIVERSITY OF SALERNO   (Italy)

^b Unibioscreen SA   (Belgium)

^c ASWAN UNIVERSITY   (Egypt)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARDENOLIDE DERIVATIVE; DIGOXIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASCLEPIADACEAE; CANCER CELL CULTURE; CANCER INHIBITION; COLORIMETRY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; PERGULARIA TOMENTOSA; PHASE CONTRAST MICROSCOPY; PLANT ROOT;

ASCLEPIADACEAE; CARDENOLIDES; GLYCOSIDES; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT ROOTS; PLANTS, MEDICINAL; SODIUM-POTASSIUM-EXCHANGING ATPASE; STRUCTURE-ACTIVITY RELATIONSHIP;

PERGULARIA TOMENTOSA;

EID: 67650246577     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np800810f     Document Type: Article

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