The novel anti-hyperglycemic effect of Paeoniae radix via the transcriptional suppression of phosphoenopyruvate carboxykinase (PEPCK)

Phytomedicine

Volumn 17, Issue 8-9, 2010, Pages 626-634

  Juan, Y C ^a   Tsai, W J ^b   Lin, Y L ^b   Wang, G J ^b   Cheng, J J ^b   Yang, H Y ^a   Hsu, C Y ^b   Liu, H K ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Diabetes; Hyperglycemia; Paeoniae Radix; Phosphoenopyruvate carboxykinase (PEPCK)

Indexed keywords

8 BROMO CYCLIC AMP; ALCOHOL; DEXAMETHASONE; INSULIN; PAEONIA RADIX; PAEONIFLORIN; PALMITIC ACID; PEONOL; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DIABETES MELLITUS; DIET SUPPLEMENTATION; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; GLUCONEOGENESIS; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; TRANSCRIPTION TERMINATION;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ACETOPHENONES; ANIMALS; BENZOIC ACIDS; BRIDGED COMPOUNDS; CELL LINE; DEXAMETHASONE; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSIDES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PAEONIA; PALMITIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHYTOTHERAPY; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY;

MUS; RATTUS;

EID: 77952290438     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.12.007     Document Type: Article

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