메뉴 건너뛰기




Volumn 27, Issue 2, 2010, Pages 138-148

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOTROPHIN; CELL LINES; CONSTANT LEVEL; CYTOPATHIC EFFECT; FOOT-AND-MOUTH DISEASE VIRUS; HOST CELL PROTEIN; HUMAN THERAPEUTICS; IN-VITRO; INSULIN-LIKE GROWTH FACTOR-I; MAMMALIAN CELLS; MUTATION RATES; PROTEIN EXPRESSIONS; RECOMBINANT PROTEIN; SEMLIKI FOREST VIRUS; SEQUENCE CODING; STABLE CELL LINES; SUPERNATANTS; THERAPEUTIC GENES;

EID: 77952237785     PISSN: 18716784     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbt.2010.02.005     Document Type: Article
Times cited : (19)

References (46)
  • 1
    • 0024514346 scopus 로고
    • Sindbis virus: an efficient, broad host range vector for gene expression in animal cells
    • Xiong C., et al. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 243 (1989) 1188-1191
    • (1989) Science , vol.243 , pp. 1188-1191
    • Xiong, C.1
  • 2
    • 14744304517 scopus 로고
    • A new generation of animal cell expression vectors based on the Semliki Forest virus replicon
    • Liljestrom P., and Garoff H. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Biotechnology (NY) 9 (1991) 1356-1361
    • (1991) Biotechnology (NY) , vol.9 , pp. 1356-1361
    • Liljestrom, P.1    Garoff, H.2
  • 3
    • 0031583842 scopus 로고    scopus 로고
    • Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo
    • Pushko P., et al. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology 239 (1997) 389-401
    • (1997) Virology , vol.239 , pp. 389-401
    • Pushko, P.1
  • 4
    • 0028088152 scopus 로고
    • The alphaviruses: gene expression, replication, and evolution
    • Strauss J.H., and Strauss E.G. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58 (1994) 491-562
    • (1994) Microbiol. Rev. , vol.58 , pp. 491-562
    • Strauss, J.H.1    Strauss, E.G.2
  • 5
    • 0031838647 scopus 로고    scopus 로고
    • Enhancing immune responses using suicidal DNA vaccines
    • Berglund P., et al. Enhancing immune responses using suicidal DNA vaccines. Nat. Biotechnol. 16 (1998) 562-565
    • (1998) Nat. Biotechnol. , vol.16 , pp. 562-565
    • Berglund, P.1
  • 6
    • 0028057720 scopus 로고
    • Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells
    • Frolov I., and Schlesinger S. Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells. J. Virol. 68 (1994) 1721-1727
    • (1994) J. Virol. , vol.68 , pp. 1721-1727
    • Frolov, I.1    Schlesinger, S.2
  • 7
    • 0030760873 scopus 로고    scopus 로고
    • Death mechanisms in cultured cells infected by Semliki Forest virus
    • Glasgow G.M., et al. Death mechanisms in cultured cells infected by Semliki Forest virus. J. Gen. Virol. 78 Pt 7 (1997) 1559-1563
    • (1997) J. Gen. Virol. , vol.78 , Issue.PART 7 , pp. 1559-1563
    • Glasgow, G.M.1
  • 8
    • 0030663897 scopus 로고    scopus 로고
    • Alphaviruses as expression vectors
    • Lundstrom K. Alphaviruses as expression vectors. Curr. Opin. Biotechnol. 8 (1997) 578-582
    • (1997) Curr. Opin. Biotechnol. , vol.8 , pp. 578-582
    • Lundstrom, K.1
  • 9
    • 0037264224 scopus 로고    scopus 로고
    • Semliki Forest virus vectors for large-scale production of recombinant proteins
    • Lundstrom K. Semliki Forest virus vectors for large-scale production of recombinant proteins. Methods Mol. Med. 76 (2003) 525-543
    • (2003) Methods Mol. Med. , vol.76 , pp. 525-543
    • Lundstrom, K.1
  • 10
    • 0036972976 scopus 로고    scopus 로고
    • Semliki forest virus-based expression for versatile use in receptor research
    • Lundstrom K. Semliki forest virus-based expression for versatile use in receptor research. J. Recept. Signal Transduct. Res. 22 (2002) 229-240
    • (2002) J. Recept. Signal Transduct. Res. , vol.22 , pp. 229-240
    • Lundstrom, K.1
  • 11
    • 0037450521 scopus 로고    scopus 로고
    • Semliki Forest virus vectors for rapid and high-level expression of integral membrane proteins
    • Lundstrom K. Semliki Forest virus vectors for rapid and high-level expression of integral membrane proteins. Biochim. Biophys. Acta 1610 (2003) 90-96
    • (2003) Biochim. Biophys. Acta , vol.1610 , pp. 90-96
    • Lundstrom, K.1
  • 12
    • 0032924734 scopus 로고    scopus 로고
    • Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells
    • Frolov I., et al. Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. J. Virol. 73 (1999) 3854-3865
    • (1999) J. Virol. , vol.73 , pp. 3854-3865
    • Frolov, I.1
  • 13
    • 0033814973 scopus 로고    scopus 로고
    • Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells
    • Perri S., et al. Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells. J. Virol. 74 (2000) 9802-9807
    • (2000) J. Virol. , vol.74 , pp. 9802-9807
    • Perri, S.1
  • 14
    • 43749111766 scopus 로고    scopus 로고
    • Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability
    • Casales E., et al. Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability. Virology 376 (2008) 242-251
    • (2008) Virology , vol.376 , pp. 242-251
    • Casales, E.1
  • 15
    • 0037301545 scopus 로고    scopus 로고
    • Novel Semliki Forest virus vectors with reduced cytotoxicity and temperature sensitivity for long-term enhancement of transgene expression
    • Lundstrom K., et al. Novel Semliki Forest virus vectors with reduced cytotoxicity and temperature sensitivity for long-term enhancement of transgene expression. Mol. Ther. 7 (2003) 202-209
    • (2003) Mol. Ther. , vol.7 , pp. 202-209
    • Lundstrom, K.1
  • 16
    • 0035098880 scopus 로고    scopus 로고
    • Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells
    • Lundstrom K., et al. Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells. Histochem. Cell Biol. 115 (2001) 83-91
    • (2001) Histochem. Cell Biol. , vol.115 , pp. 83-91
    • Lundstrom, K.1
  • 17
    • 42449119438 scopus 로고    scopus 로고
    • Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus
    • Tamm K., et al. Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus. J. Gen. Virol. 89 (2008) 676-686
    • (2008) J. Gen. Virol. , vol.89 , pp. 676-686
    • Tamm, K.1
  • 18
    • 19944373420 scopus 로고    scopus 로고
    • Noncytopathic replication of Venezuelan equine encephalitis virus and eastern equine encephalitis virus replicons in Mammalian cells
    • Petrakova O., et al. Noncytopathic replication of Venezuelan equine encephalitis virus and eastern equine encephalitis virus replicons in Mammalian cells. J. Virol. 79 (2005) 7597-7608
    • (2005) J. Virol. , vol.79 , pp. 7597-7608
    • Petrakova, O.1
  • 19
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: biological actions
    • Jones J.I., and Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16 (1995) 3-34
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 20
    • 0026533360 scopus 로고
    • Effects of insulin-like growth factor on linear growth, head circumference, and body fat in patients with Laron-type dwarfism
    • Laron Z., et al. Effects of insulin-like growth factor on linear growth, head circumference, and body fat in patients with Laron-type dwarfism. Lancet 339 (1992) 1258-1261
    • (1992) Lancet , vol.339 , pp. 1258-1261
    • Laron, Z.1
  • 21
    • 0034001305 scopus 로고    scopus 로고
    • Insulin-like growth factor-I reverts testicular atrophy in rats with advanced cirrhosis
    • Castilla-Cortazar I., et al. Insulin-like growth factor-I reverts testicular atrophy in rats with advanced cirrhosis. Hepatology 31 (2000) 592-600
    • (2000) Hepatology , vol.31 , pp. 592-600
    • Castilla-Cortazar, I.1
  • 22
    • 24344474237 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial
    • Conchillo M., et al. Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial. J. Hepatol. 43 (2005) 630-636
    • (2005) J. Hepatol. , vol.43 , pp. 630-636
    • Conchillo, M.1
  • 23
    • 0028816906 scopus 로고
    • Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy
    • Pennica D., et al. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 1142-1146
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 1142-1146
    • Pennica, D.1
  • 24
    • 0034940330 scopus 로고    scopus 로고
    • Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation
    • Brar B.K., et al. Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation. Cardiovasc. Res. 51 (2001) 265-274
    • (2001) Cardiovasc. Res. , vol.51 , pp. 265-274
    • Brar, B.K.1
  • 25
    • 0038730615 scopus 로고    scopus 로고
    • Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats
    • Bustos M., et al. Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats. Gastroenterology 125 (2003) 192-201
    • (2003) Gastroenterology , vol.125 , pp. 192-201
    • Bustos, M.1
  • 26
    • 23744439101 scopus 로고    scopus 로고
    • Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro
    • Wen T.C., et al. Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro. Neurosci. Lett. 387 (2005) 38-42
    • (2005) Neurosci. Lett. , vol.387 , pp. 38-42
    • Wen, T.C.1
  • 27
    • 33947362493 scopus 로고    scopus 로고
    • Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis
    • Marques J.M., et al. Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis. Hepatology 45 (2007) 639-648
    • (2007) Hepatology , vol.45 , pp. 639-648
    • Marques, J.M.1
  • 28
    • 33845878554 scopus 로고    scopus 로고
    • Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning
    • Iniguez M., et al. Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning. J. Exp. Med. 203 (2006) 2809-2815
    • (2006) J. Exp. Med. , vol.203 , pp. 2809-2815
    • Iniguez, M.1
  • 29
    • 0028058011 scopus 로고
    • Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein
    • Ryan M.D., and Drew J. Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein. EMBO J. 13 (1994) 928-933
    • (1994) EMBO J. , vol.13 , pp. 928-933
    • Ryan, M.D.1    Drew, J.2
  • 30
    • 0001803818 scopus 로고
    • Expression of proteins using Semliki Forest virus vectors
    • Ausubel F.M., et al. (Ed), Greene Publishing Associates and Wiley Interscience
    • Liljestrom P., and Garoff H. Expression of proteins using Semliki Forest virus vectors. In: Ausubel F.M., et al. (Ed). Current Protocols in Molecular Biology (1994), Greene Publishing Associates and Wiley Interscience 16.20.11-16.20.16
    • (1994) Current Protocols in Molecular Biology
    • Liljestrom, P.1    Garoff, H.2
  • 31
    • 0033039916 scopus 로고    scopus 로고
    • Large-scale transient expression in mammalian cells for recombinant protein production
    • Wurm F., and Bernard A. Large-scale transient expression in mammalian cells for recombinant protein production. Curr. Opin. Biotechnol. 10 (1999) 156-159
    • (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 156-159
    • Wurm, F.1    Bernard, A.2
  • 32
    • 0037457338 scopus 로고    scopus 로고
    • Stability of protein production from recombinant mammalian cells
    • Barnes L.M., et al. Stability of protein production from recombinant mammalian cells. Biotechnol. Bioeng. 81 (2003) 631-639
    • (2003) Biotechnol. Bioeng. , vol.81 , pp. 631-639
    • Barnes, L.M.1
  • 33
    • 31444448624 scopus 로고    scopus 로고
    • E unum pluribus: multiple proteins from a self-processing polyprotein
    • de Felipe P., et al. E unum pluribus: multiple proteins from a self-processing polyprotein. Trends Biotechnol. 24 (2006) 68-75
    • (2006) Trends Biotechnol. , vol.24 , pp. 68-75
    • de Felipe, P.1
  • 34
    • 20844456858 scopus 로고    scopus 로고
    • Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas
    • Rodriguez-Madoz J.R., et al. Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas. Mol. Ther. 12 (2005) 153-163
    • (2005) Mol. Ther. , vol.12 , pp. 153-163
    • Rodriguez-Madoz, J.R.1
  • 35
    • 0032906979 scopus 로고    scopus 로고
    • Two-helper RNA system for production of recombinant Semliki Forest virus particles
    • Smerdou C., and Liljestrom P. Two-helper RNA system for production of recombinant Semliki Forest virus particles. J. Virol. 73 (1999) 1092-1098
    • (1999) J. Virol. , vol.73 , pp. 1092-1098
    • Smerdou, C.1    Liljestrom, P.2
  • 36
    • 0032699093 scopus 로고    scopus 로고
    • Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy
    • Bordet T., et al. Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy. J. Clin. Invest. 104 (1999) 1077-1085
    • (1999) J. Clin. Invest. , vol.104 , pp. 1077-1085
    • Bordet, T.1
  • 37
    • 0023664821 scopus 로고
    • Expression of human insulin-like growth factor I in bacteria: use of optimized gene fusion vectors to facilitate protein purification
    • Moks T., et al. Expression of human insulin-like growth factor I in bacteria: use of optimized gene fusion vectors to facilitate protein purification. Biochemistry 26 (1987) 5239-5244
    • (1987) Biochemistry , vol.26 , pp. 5239-5244
    • Moks, T.1
  • 38
    • 0023933481 scopus 로고
    • Expression, purification and characterization of recombinant human insulin-like growth factor I in yeast
    • Bayne M.L., et al. Expression, purification and characterization of recombinant human insulin-like growth factor I in yeast. Gene 66 (1988) 235-244
    • (1988) Gene , vol.66 , pp. 235-244
    • Bayne, M.L.1
  • 39
    • 65549122095 scopus 로고    scopus 로고
    • Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function
    • Daniell H., et al. Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function. BMC Biotechnol. 9 (2009) 33
    • (2009) BMC Biotechnol. , vol.9 , pp. 33
    • Daniell, H.1
  • 40
    • 43449123620 scopus 로고    scopus 로고
    • High-density seedling expression system for the production of bioactive human cardiotrophin-1, a potential therapeutic cytokine, in transgenic tobacco chloroplasts
    • Farran I., et al. High-density seedling expression system for the production of bioactive human cardiotrophin-1, a potential therapeutic cytokine, in transgenic tobacco chloroplasts. Plant Biotechnol. J. 6 (2008) 516-527
    • (2008) Plant Biotechnol. J. , vol.6 , pp. 516-527
    • Farran, I.1
  • 41
    • 0027943965 scopus 로고
    • Large scale, in situ isolation of periplasmic IGF-I from E. coli
    • Hart R.A., et al. Large scale, in situ isolation of periplasmic IGF-I from E. coli. Biotechnology (NY) 12 (1994) 1113-1117
    • (1994) Biotechnology (NY) , vol.12 , pp. 1113-1117
    • Hart, R.A.1
  • 42
    • 0030592124 scopus 로고    scopus 로고
    • High-level expression and simple purification of recombinant human insulin-like growth factor I
    • Kim S.O., and Lee Y.I. High-level expression and simple purification of recombinant human insulin-like growth factor I. J. Biotechnol. 48 (1996) 97-105
    • (1996) J. Biotechnol. , vol.48 , pp. 97-105
    • Kim, S.O.1    Lee, Y.I.2
  • 43
    • 0026503891 scopus 로고
    • Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu3, following their expression in Escherichia coli as fusion proteins
    • King R., et al. Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu3, following their expression in Escherichia coli as fusion proteins. J. Mol. Endocrinol. 8 (1992) 29-41
    • (1992) J. Mol. Endocrinol. , vol.8 , pp. 29-41
    • King, R.1
  • 44
    • 0023221520 scopus 로고
    • Expression of a synthetic gene encoding human insulin-like growth factor I in cultured mouse fibroblasts
    • Bayne M.L., et al. Expression of a synthetic gene encoding human insulin-like growth factor I in cultured mouse fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 2638-2642
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 2638-2642
    • Bayne, M.L.1
  • 45
    • 0031003396 scopus 로고    scopus 로고
    • Chinese hamster ovary cells produce sufficient recombinant insulin-like growth factor I to support growth in serum-free medium. Serum-free growth of IGF-I producing CHO cells
    • Hunt S.M.N., et al. Chinese hamster ovary cells produce sufficient recombinant insulin-like growth factor I to support growth in serum-free medium. Serum-free growth of IGF-I producing CHO cells. Cytotechnology 24 (1997) 55-64
    • (1997) Cytotechnology , vol.24 , pp. 55-64
    • Hunt, S.M.N.1
  • 46
    • 0025909312 scopus 로고
    • Expression, purification and characterization of secreted recombinant human insulin-like growth factor-I (IGF-I) and the potent variant des(1-3) IGF-I in Chinese hamster ovary cells
    • McKinnon P., et al. Expression, purification and characterization of secreted recombinant human insulin-like growth factor-I (IGF-I) and the potent variant des(1-3) IGF-I in Chinese hamster ovary cells. J. Mol. Endocrinol. 6 (1991) 231-239
    • (1991) J. Mol. Endocrinol. , vol.6 , pp. 231-239
    • McKinnon, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.