-
1
-
-
0035966059
-
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway
-
Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA, et al. Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway. J Biol Chem 2001;276:49077-49082.
-
(2001)
J Biol Chem
, vol.276
, pp. 49077-49082
-
-
Faouzi, S.1
Burckhardt, B.E.2
Hanson, J.C.3
Campe, C.B.4
Schrum, L.W.5
Rippe, R.A.6
-
2
-
-
1242336980
-
Apoptosis: The nexus of liver injury and fibrosis
-
Canbay A, Friedman S, Gores GJ. Apoptosis: the nexus of liver injury and fibrosis. HEPATOLOGY 2004;39:273-278.
-
(2004)
HEPATOLOGY
, vol.39
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
3
-
-
7044220856
-
Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury
-
Bantel H, Lugering A, Heidemann J, Volkmann X, Poremba C, Strassburg CP, et al. Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury. HEPATOLOGY 2004;40:1078-1087.
-
(2004)
HEPATOLOGY
, vol.40
, pp. 1078-1087
-
-
Bantel, H.1
Lugering, A.2
Heidemann, J.3
Volkmann, X.4
Poremba, C.5
Strassburg, C.P.6
-
4
-
-
0142151769
-
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
-
Canbay A, Feldstein AE, Higuchi H, Werneburg N, Grambihler A, Bronk SF, et al. Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. HEPATOLOGY 2003;38:1188-1198.
-
(2003)
HEPATOLOGY
, vol.38
, pp. 1188-1198
-
-
Canbay, A.1
Feldstein, A.E.2
Higuchi, H.3
Werneburg, N.4
Grambihler, A.5
Bronk, S.F.6
-
5
-
-
33644524120
-
Apoptosis and necrosis in the liver: A tale of two deaths?
-
Malhi H, Gores GJ, Lemasters JJ. Apoptosis and necrosis in the liver: a tale of two deaths? HEPATOLOGY 2006;43:S31-S44.
-
(2006)
HEPATOLOGY
, vol.43
-
-
Malhi, H.1
Gores, G.J.2
Lemasters, J.J.3
-
6
-
-
0027291205
-
Lethal effect of the anti-Fas antibody in mice
-
Ogasawara J, Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugai T, Kitamura Y, et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993;364:806-809.
-
(1993)
Nature
, vol.364
, pp. 806-809
-
-
Ogasawara, J.1
Watanabe-Fukunaga, R.2
Adachi, M.3
Matsuzawa, A.4
Kasugai, T.5
Kitamura, Y.6
-
7
-
-
85047689502
-
Hepatoprotection via the IL-6/Stat3 pathway
-
Taub R. Hepatoprotection via the IL-6/Stat3 pathway. J Clin Invest 2003;112:978-980.
-
(2003)
J Clin Invest
, vol.112
, pp. 978-980
-
-
Taub, R.1
-
8
-
-
0036256644
-
What does Stat3 do?
-
Levy DE, Lee CK. What does Stat3 do? J Clin Invest 2002;109:1143-1148.
-
(2002)
J Clin Invest
, vol.109
, pp. 1143-1148
-
-
Levy, D.E.1
Lee, C.K.2
-
9
-
-
0038730615
-
Protection against liver damage by cardiotrophin-1: A hepatocyte survival factor up-regulated in the regenerating liver in rats
-
Bustos M, Beraza N, Lasarte JJ, Baixeras E, Alzuguren P, Bordet T, et al. Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats. Gastroenterology 2003;125:192-201.
-
(2003)
Gastroenterology
, vol.125
, pp. 192-201
-
-
Bustos, M.1
Beraza, N.2
Lasarte, J.J.3
Baixeras, E.4
Alzuguren, P.5
Bordet, T.6
-
10
-
-
0035866059
-
Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons
-
Oppenheim RW, Wiese S, Prevette D, Armanini M, Wang S, Houenou LJ, et al. Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons. J Neurosci 2001;21:1283-1291.
-
(2001)
J Neurosci
, vol.21
, pp. 1283-1291
-
-
Oppenheim, R.W.1
Wiese, S.2
Prevette, D.3
Armanini, M.4
Wang, S.5
Houenou, L.J.6
-
11
-
-
14244262565
-
Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration
-
Beraza N, Marques JM, Martinez-Anso E, Iniguez M, Prieto J, Bustos M. Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration. HEPATOLOGY 2005;41:460-469.
-
(2005)
HEPATOLOGY
, vol.41
, pp. 460-469
-
-
Beraza, N.1
Marques, J.M.2
Martinez-Anso, E.3
Iniguez, M.4
Prieto, J.5
Bustos, M.6
-
12
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
13
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 2000;25:25-29.
-
(2000)
Nat Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
Cherry, J.M.6
-
14
-
-
44649171642
-
-
Segura V, Podhorski A, Guruceaga E, Sevilla JL, Corrales FJ, Rubio A. GARBAN II: An integrative framework for extracting biological information from proteomic and genomic data. Proteomics 2006;6(Suppl 1):S12-S15.
-
Segura V, Podhorski A, Guruceaga E, Sevilla JL, Corrales FJ, Rubio A. GARBAN II: An integrative framework for extracting biological information from proteomic and genomic data. Proteomics 2006;6(Suppl 1):S12-S15.
-
-
-
-
15
-
-
0242348793
-
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms
-
Haga S, Terui K, Zhang HQ, Enosawa S, Ogawa W, Inoue H, et al. Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J Clin Invest 2003;112:989-998.
-
(2003)
J Clin Invest
, vol.112
, pp. 989-998
-
-
Haga, S.1
Terui, K.2
Zhang, H.Q.3
Enosawa, S.4
Ogawa, W.5
Inoue, H.6
-
16
-
-
33746139034
-
Altered expression and activation of STATs (signal transduction and activator of transcription) in HCV infection: In vivo and in vitro studies
-
Larrea E, Aldabe R, Molano E, Fernandez-Rodriguez CM, Ametzazurra A, Civeira MP, et al. Altered expression and activation of STATs (signal transduction and activator of transcription) in HCV infection: in vivo and in vitro studies. Gut 2005;55:1188-1196.
-
(2005)
Gut
, vol.55
, pp. 1188-1196
-
-
Larrea, E.1
Aldabe, R.2
Molano, E.3
Fernandez-Rodriguez, C.M.4
Ametzazurra, A.5
Civeira, M.P.6
-
17
-
-
0035854780
-
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL
-
Kovalovich K, Li W, DeAngelis R, Greenbaum LE, Ciliberto G, Taub R. Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. J Biol Chem 2001;276:26605-26613.
-
(2001)
J Biol Chem
, vol.276
, pp. 26605-26613
-
-
Kovalovich, K.1
Li, W.2
DeAngelis, R.3
Greenbaum, L.E.4
Ciliberto, G.5
Taub, R.6
-
18
-
-
13344279418
-
Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice
-
Lacronique V, Mignon A, Fabre M, Viollet B, Rouquet N, Molina T, et al. Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice. Nat Med 1996;2:80-86.
-
(1996)
Nat Med
, vol.2
, pp. 80-86
-
-
Lacronique, V.1
Mignon, A.2
Fabre, M.3
Viollet, B.4
Rouquet, N.5
Molina, T.6
-
19
-
-
0031028140
-
Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
-
Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc Natl Acad Sci U S A 1997;94:1441-1446.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1441-1446
-
-
Yamada, Y.1
Kirillova, I.2
Peschon, J.J.3
Fausto, N.4
-
20
-
-
0037248312
-
Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice
-
Leu JI, Crissey MA, Taub R. Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice. J Clin Invest 2003;111:129-139.
-
(2003)
J Clin Invest
, vol.111
, pp. 129-139
-
-
Leu, J.I.1
Crissey, M.A.2
Taub, R.3
-
21
-
-
0032898002
-
Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis
-
Kohli V, Madden JF, Bentley RC, Clavien PA. Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis. Gastroenterology 1999;116:168-178.
-
(1999)
Gastroenterology
, vol.116
, pp. 168-178
-
-
Kohli, V.1
Madden, J.F.2
Bentley, R.C.3
Clavien, P.A.4
-
22
-
-
0042733742
-
Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants
-
Limaye PB, Apte UM, Shankar K, Bucci TJ, Warbritton A, Mehendale HM. Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants. Toxicol Appl Pharmacol 2003;191:211-226.
-
(2003)
Toxicol Appl Pharmacol
, vol.191
, pp. 211-226
-
-
Limaye, P.B.1
Apte, U.M.2
Shankar, K.3
Bucci, T.J.4
Warbritton, A.5
Mehendale, H.M.6
-
23
-
-
0034060334
-
Apoptosis and liver disease
-
Rust C, Gores GJ. Apoptosis and liver disease. Am J Med 2000;108:567-574.
-
(2000)
Am J Med
, vol.108
, pp. 567-574
-
-
Rust, C.1
Gores, G.J.2
-
24
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003;125:437-443.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
-
25
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003;9:347-351.
-
(2003)
Nat Med
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
Ince, N.4
Ouyang, N.5
Min, J.6
-
26
-
-
0031002790
-
Essential roles of the Fas ligand in the development of hepatitis
-
Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S. Essential roles of the Fas ligand in the development of hepatitis. Nat Med 1997;3:409-413.
-
(1997)
Nat Med
, vol.3
, pp. 409-413
-
-
Kondo, T.1
Suda, T.2
Fukuyama, H.3
Adachi, M.4
Nagata, S.5
-
27
-
-
0033067527
-
Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice
-
Kosai K, Matsumoto K, Funakoshi H, Nakamura T. Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice. HEPATOLOGY 1999;30:151-159.
-
(1999)
HEPATOLOGY
, vol.30
, pp. 151-159
-
-
Kosai, K.1
Matsumoto, K.2
Funakoshi, H.3
Nakamura, T.4
-
28
-
-
21444455580
-
Novel role for amphiregulin in protection from liver injury
-
Berasain C, Garcia-Trevijano ER, Castillo J, Erroba E, Santamaria M, Lee DC, et al. Novel role for amphiregulin in protection from liver injury. J Biol Chem 2005;280:19012-19020.
-
(2005)
J Biol Chem
, vol.280
, pp. 19012-19020
-
-
Berasain, C.1
Garcia-Trevijano, E.R.2
Castillo, J.3
Erroba, E.4
Santamaria, M.5
Lee, D.C.6
-
29
-
-
33646149962
-
In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: A comparative study to HGF
-
Khai NC, Takahashi T, Ushikoshi H, Nagano S, Yuge K, Esaki M, et al. In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: a comparative study to HGF. J Hepatol 2006;44:1046-1054.
-
(2006)
J Hepatol
, vol.44
, pp. 1046-1054
-
-
Khai, N.C.1
Takahashi, T.2
Ushikoshi, H.3
Nagano, S.4
Yuge, K.5
Esaki, M.6
-
30
-
-
32944463507
-
-
Gao B. Cytokines, STATs and liver disease. Cell Mol Immunol 2005;2:92-100.
-
Gao B. Cytokines, STATs and liver disease. Cell Mol Immunol 2005;2:92-100.
-
-
-
-
32
-
-
29144528036
-
STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells
-
Bhattacharya S, Ray RM, Johnson LR. STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. Biochem J 2005;392:335-344.
-
(2005)
Biochem J
, vol.392
, pp. 335-344
-
-
Bhattacharya, S.1
Ray, R.M.2
Johnson, L.R.3
-
33
-
-
0028895940
-
Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release
-
Leist M, Gantner F, Jilg S, Wendel A. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol 1995;154:1307-1316.
-
(1995)
J Immunol
, vol.154
, pp. 1307-1316
-
-
Leist, M.1
Gantner, F.2
Jilg, S.3
Wendel, A.4
-
34
-
-
0141503509
-
Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1: Potential role of inflammatory mediators
-
Gardner CR, Laskin JD, Dambach DM, Chiu H, Durham SK, Zhou P, et al. Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1: potential role of inflammatory mediators. Toxicol Appl Pharmacol 2003;192:119-130.
-
(2003)
Toxicol Appl Pharmacol
, vol.192
, pp. 119-130
-
-
Gardner, C.R.1
Laskin, J.D.2
Dambach, D.M.3
Chiu, H.4
Durham, S.K.5
Zhou, P.6
-
35
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
Dauer DJ, Ferraro B, Song L, Yu B, Mora L, Buettner R, et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene 2005;24:3397-3408.
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
Ferraro, B.2
Song, L.3
Yu, B.4
Mora, L.5
Buettner, R.6
-
36
-
-
26444609646
-
Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion
-
Barrier A, Olaya N, Chiappini F, Roser F, Scatton O, Artus C, et al. Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion. FASEB J 2005;19:1617-1626.
-
(2005)
FASEB J
, vol.19
, pp. 1617-1626
-
-
Barrier, A.1
Olaya, N.2
Chiappini, F.3
Roser, F.4
Scatton, O.5
Artus, C.6
-
37
-
-
0029925907
-
A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia
-
Arora AS, de Groen P, Emori Y, Gores GJ. A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia. Am J Physiol 1996;270:G238-G245.
-
(1996)
Am J Physiol
, vol.270
-
-
Arora, A.S.1
de Groen, P.2
Emori, Y.3
Gores, G.J.4
-
39
-
-
18144391161
-
Calpain: A death protein that mediates progression of liver injury
-
Mehendale HM, Limaye PB. Calpain: a death protein that mediates progression of liver injury. Trends Pharmacol Sci 2005;26:232-236.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 232-236
-
-
Mehendale, H.M.1
Limaye, P.B.2
|