Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas

Molecular Therapy

Volumn 12, Issue 1, 2005, Pages 153-163

  Rodriguez Madoz, Juan R ^a   Prieto, Jesus ^a   Smerdou, Cristian ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Colon adenocarcinoma; Gene therapy; IL 12; MC38; Semliki Forest virus vectors; SFV translation enhancer

Indexed keywords

INTERLEUKIN 12; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER REGRESSION; CANCER SURVIVAL; CELLULAR IMMUNITY; COLON ADENOCARCINOMA; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOTOXIC T LYMPHOCYTE; DOSE RESPONSE; DRUG RESPONSE; FEMALE; GENE THERAPY; IMMUNOGENICITY; MOUSE; NONHUMAN; PHARMACEUTICAL ENGINEERING; PROMOTER REGION; PROTEIN EXPRESSION; SEMLIKI FOREST ALPHAVIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS PARTICLE; VIRUS TRANSCRIPTION;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; GENE THERAPY; GENETIC VECTORS; IMMUNITY, CELLULAR; INTERLEUKIN-12; MICE; SEMLIKI FOREST VIRUS; T-LYMPHOCYTES, CYTOTOXIC;

ADENOVIRIDAE; ALPHAVIRUS; ANIMALIA; MIRIDAE; MURINAE; RABBIT FIBROMA VIRUS; SEMLIKI FOREST VIRUS;

EID: 20844456858     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.02.011     Document Type: Article

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