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Volumn 88, Issue 4, 2010, Pages 431-437

Langerhans cells as targets for immunotherapy against skin cancer

Author keywords

Immunotherapy; Langerhans cells; Skin immunology

Indexed keywords

AGGRIPAL; CHOLERA TOXIN; CPG OLIGODEOXYNUCLEOTIDE; ESCHERICHIA COLI ENTEROTOXIN; GLYCOPROTEIN GP 100; HLA ANTIGEN CLASS 1; IMIQUIMOD; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; LANGERIN; MELANOMA ANTIGEN; OVALBUMIN; PROTEIN E7; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 77952222437     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.31     Document Type: Review
Times cited : (47)

References (96)
  • 1
    • 77349112874 scopus 로고    scopus 로고
    • Langerhans cells and more: Langerin-expressing dendritic cell subsets in the skin
    • Romani N, Clausen B, Stoitzner P. Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. Immunol Rev 2010; 234: 120-141.
    • (2010) Immunol Rev , vol.234 , pp. 120-141
    • Romani, N.1    Clausen, B.2    Stoitzner, P.3
  • 2
    • 37549019986 scopus 로고    scopus 로고
    • The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells
    • Poulin LF, Henri S, de Bovis B, Devilard E, Kissenpfennig A, Malissen B. The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med 2007; 204: 3119-3131.
    • (2007) J Exp Med , vol.204 , pp. 3119-3131
    • Poulin, L.F.1    Henri, S.2    De Bovis, B.3    Devilard, E.4    Kissenpfennig, A.5    Malissen, B.6
  • 3
    • 37549030450 scopus 로고    scopus 로고
    • Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state
    • Ginhoux F, Collin MP, Bogunovic M, Abel M, Leboeuf M, Helft J et al. Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med 2007; 204: 3133-3146.
    • (2007) J Exp Med , vol.204 , pp. 3133-3146
    • Ginhoux, F.1    Collin, M.P.2    Bogunovic, M.3    Abel, M.4    Leboeuf, M.5    Helft, J.6
  • 6
    • 0037141023 scopus 로고    scopus 로고
    • Rapid induction of tumor-specific type 1T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells
    • Schuler-Thurner B, Schultz ES, Berger TG, Weinlich G, Ebner S, Woerl P et al. Rapid induction of tumor-specific type 1T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells. J Exp Med 2002; 195: 1279-1288.
    • (2002) J Exp Med , vol.195 , pp. 1279-1288
    • Schuler-Thurner, B.1    Schultz, E.S.2    Berger, T.G.3    Weinlich, G.4    Ebner, S.5    Woerl, P.6
  • 7
    • 35748978808 scopus 로고    scopus 로고
    • Taming cancer by inducing immunity via dendritic cells
    • Palucka AK, Ueno H, Fay JW, Banchereau J. Taming cancer by inducing immunity via dendritic cells. Immunol Rev 2007; 220: 129-150.
    • (2007) Immunol Rev , vol.220 , pp. 129-150
    • Palucka, A.K.1    Ueno, H.2    Fay, J.W.3    Banchereau, J.4
  • 9
    • 0141678964 scopus 로고    scopus 로고
    • Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    • Bynoe MS, Evans JT, Viret C, Janeway Jr CA. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity 2003; 19: 317-328.
    • (2003) Immunity , vol.19 , pp. 317-328
    • Bynoe, M.S.1    Evans, J.T.2    Viret, C.3    Janeway Jr, C.A.4
  • 10
    • 33847775164 scopus 로고    scopus 로고
    • Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage
    • Nikolic WV, Bai Y, Obregon D, Hou H, Mori T, Zeng J et al. Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage. Proc Natl Acad Sci USA 2007; 104: 2507-2512.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2507-2512
    • Nikolic, W.V.1    Bai, Y.2    Obregon, D.3    Hou, H.4    Mori, T.5    Zeng, J.6
  • 11
    • 0034602670 scopus 로고    scopus 로고
    • Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis
    • Seo N, Tokura Y, Nishijima T, Hashizume H, Furukawa F, Takigawa M. Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis. Proc Natl Acad Sci USA 2000; 97: 371-376.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 371-376
    • Seo, N.1    Tokura, Y.2    Nishijima, T.3    Hashizume, H.4    Furukawa, F.5    Takigawa, M.6
  • 12
    • 33750561918 scopus 로고    scopus 로고
    • Induction of therapeutically relevant cytotoxic T lymphocytes in humans by percutaneous peptide immunization
    • Yagi H, Hashizume H, Horibe T, Yoshinari Y, Hata M, Ohshima A et al. Induction of therapeutically relevant cytotoxic T lymphocytes in humans by percutaneous peptide immunization. Cancer Res 2006; 66: 10136-10144.
    • (2006) Cancer Res , vol.66 , pp. 10136-10144
    • Yagi, H.1    Hashizume, H.2    Horibe, T.3    Yoshinari, Y.4    Hata, M.5    Ohshima, A.6
  • 13
    • 28844462706 scopus 로고    scopus 로고
    • Transcutaneous immunization in mice: Induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus-induced tumors
    • Dell K, Koesters R, Gissmann L. Transcutaneous immunization in mice: induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus- induced tumors. Int J Cancer 2006; 118: 364-372.
    • (2006) Int J Cancer , vol.118 , pp. 364-372
    • Dell, K.1    Koesters, R.2    Gissmann, L.3
  • 14
    • 45549087926 scopus 로고    scopus 로고
    • Memory Th1 cells augment tumor-specific CTL following transcutaneous peptide immunization
    • Hosoi A, Takeda Y, Furuichi Y, Kurachi M, Kimura K, Maekawa R et al. Memory Th1 cells augment tumor-specific CTL following transcutaneous peptide immunization. Cancer Res 2008; 68: 3941-3949.
    • (2008) Cancer Res , vol.68 , pp. 3941-3949
    • Hosoi, A.1    Takeda, Y.2    Furuichi, Y.3    Kurachi, M.4    Kimura, K.5    Maekawa, R.6
  • 15
    • 0032184817 scopus 로고    scopus 로고
    • Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge
    • Glenn GM, Scharton-Kersten T, Vassell R, Mallett CP, Hale TL, Alving CR. Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge. J Immunol 1998; 161: 3211-3214.
    • (1998) J Immunol , vol.161 , pp. 3211-3214
    • Glenn, G.M.1    Scharton-Kersten, T.2    Vassell, R.3    Mallett, C.P.4    Hale, T.L.5    Alving, C.R.6
  • 16
    • 0035925699 scopus 로고    scopus 로고
    • Transcutaneous immunization: T cell responses and boosting of existing immunity
    • Hammond SA, Walwender D, Alving CR, Glenn GM. Transcutaneous immunization: T cell responses and boosting of existing immunity. Vaccine 2001; 19: 2701-2707.
    • (2001) Vaccine , vol.19 , pp. 2701-2707
    • Hammond, S.A.1    Walwender, D.2    Alving, C.R.3    Glenn, G.M.4
  • 17
    • 0035074385 scopus 로고    scopus 로고
    • Immunization onto bare skin with heatlabile enterotoxin of Escherichia coli enhances immune responses to coadministered protein and peptide antigens and protects mice against lethal toxin challenge
    • Beignon AS, Briand JP, Muller S, Partidos CD. Immunization onto bare skin with heatlabile enterotoxin of Escherichia coli enhances immune responses to coadministered protein and peptide antigens and protects mice against lethal toxin challenge. Immunology 2001; 102: 344-351.
    • (2001) Immunology , vol.102 , pp. 344-351
    • Beignon, A.S.1    Briand, J.P.2    Muller, S.3    Partidos, C.D.4
  • 18
    • 44949230030 scopus 로고    scopus 로고
    • Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: A phase II, randomised, double-blind, placebo-controlled field trial
    • Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF et al. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet 2008; 371: 2019-2025.
    • (2008) Lancet , vol.371 , pp. 2019-2025
    • Frech, S.A.1    Dupont, H.L.2    Bourgeois, A.L.3    McKenzie, R.4    Belkind-Gerson, J.5    Figueroa, J.F.6
  • 19
    • 40749131709 scopus 로고    scopus 로고
    • Transcutaneous anti-influenza vaccination promotes both CD4 and CD8T cell immune responses in humans
    • Vogt A, Mahe B, Costagliola D, Bonduelle O, Hadam S, Schaefer G et al. Transcutaneous anti-influenza vaccination promotes both CD4 and CD8T cell immune responses in humans. J Immunol 2008; 180: 1482-1489.
    • (2008) J Immunol , vol.180 , pp. 1482-1489
    • Vogt, A.1    Mahe, B.2    Costagliola, D.3    Bonduelle, O.4    Hadam, S.5    Schaefer, G.6
  • 20
    • 1642272033 scopus 로고    scopus 로고
    • Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells
    • Belyakov IM, Hammond SA, Ahlers JD, Glenn GM, Berzofsky JA. Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells. J Clin Invest 2004; 113: 998-1007.
    • (2004) J Clin Invest , vol.113 , pp. 998-1007
    • Belyakov, I.M.1    Hammond, S.A.2    Ahlers, J.D.3    Glenn, G.M.4    Berzofsky, J.A.5
  • 21
    • 0024549594 scopus 로고
    • Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells
    • Romani N, Koide S, Crowley M, Witmer-Pack M, Livingstone AM, Fathman CG et al. Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells. J Exp Med 1989; 169: 1169-1178.
    • (1989) J Exp Med , vol.169 , pp. 1169-1178
    • Romani, N.1    Koide, S.2    Crowley, M.3    Witmer-Pack, M.4    Livingstone, A.M.5    Fathman, C.G.6
  • 22
    • 0021917676 scopus 로고
    • Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro
    • DOI 10.1084/jem.161.3.526
    • Schuler G, Steinman RM. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp Med 1985; 161: 526-546. (Pubitemid 15142803)
    • (1985) Journal of Experimental Medicine , vol.161 , Issue.3 , pp. 526-546
    • Schuler, G.1    Steinman, R.M.2
  • 23
    • 4043055798 scopus 로고    scopus 로고
    • Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermal-interstitial or monocyte-derived dendritic cells
    • Ratzinger G, Baggers J, de Cos MA, Yuan J, Dao T, Reagan JL et al. Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermal-interstitial or monocyte-derived dendritic cells. J Immunol 2004; 173: 2780-2791.
    • (2004) J Immunol , vol.173 , pp. 2780-2791
    • Ratzinger, G.1    Baggers, J.2    De Cos, M.A.3    Yuan, J.4    Dao, T.5    Reagan, J.L.6
  • 24
    • 34548735414 scopus 로고    scopus 로고
    • Both Langerhans cells and interstitial DC cross-present melanoma antigens and efficiently activate antigenspecific CTL
    • Cao T, Ueno H, Glaser C, Fay JW, Palucka AK, Banchereau J. Both Langerhans cells and interstitial DC cross-present melanoma antigens and efficiently activate antigenspecific CTL. Eur J Immunol 2007; 37: 2657-2667.
    • (2007) Eur J Immunol , vol.37 , pp. 2657-2667
    • Cao, T.1    Ueno, H.2    Glaser, C.3    Fay, J.W.4    Palucka, A.K.5    Banchereau, J.6
  • 25
    • 33745603724 scopus 로고    scopus 로고
    • Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells
    • Fay JW, Palucka AK, Paczesny S, Dhodapkar M, Johnston DA, Burkeholder S et al. Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells. Cancer Immunol Immunother 2006; 55: 1209-1218.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1209-1218
    • Fay, J.W.1    Palucka, A.K.2    Paczesny, S.3    Dhodapkar, M.4    Johnston, D.A.5    Burkeholder, S.6
  • 27
    • 0036147899 scopus 로고    scopus 로고
    • Specific peptide-mediated immunity against established melanoma tumors with dendritic cells requires IL-2 and fetal calf serum-free cell culture
    • Eggert AO, Becker JC, Ammon M, McLellan AD, Renner G, Merkel A et al. Specific peptide-mediated immunity against established melanoma tumors with dendritic cells requires IL-2 and fetal calf serum-free cell culture. Eur J Immunol 2002; 32: 122-127.
    • (2002) Eur J Immunol , vol.32 , pp. 122-127
    • Eggert, A.O.1    Becker, J.C.2    Ammon, M.3    McLellan, A.D.4    Renner, G.5    Merkel, A.6
  • 29
    • 0033984930 scopus 로고    scopus 로고
    • Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules
    • Valladeau J, Ravel O, Dezutter-Dambuyant C, Moore K, Kleijmeer M, Liu Y et al. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 2000; 12: 71-81.
    • (2000) Immunity , vol.12 , pp. 71-81
    • Valladeau, J.1    Ravel, O.2    Dezutter-Dambuyant, C.3    Moore, K.4    Kleijmeer, M.5    Liu, Y.6
  • 31
    • 0037289787 scopus 로고    scopus 로고
    • Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207
    • Stoitzner P, Holzmann S, McLellan AD, Ivarsson L, Stossel H, Kapp M et al. Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207. J Invest Dermatol 2003; 120: 266-274.
    • (2003) J Invest Dermatol , vol.120 , pp. 266-274
    • Stoitzner, P.1    Holzmann, S.2    McLellan, A.D.3    Ivarsson, L.4    Stossel, H.5    Kapp, M.6
  • 32
    • 22344443257 scopus 로고    scopus 로고
    • Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity
    • Bennett CL, van Rijn E, Jung S, Inaba K, Steinman RM, Kapsenberg ML et al. Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol 2005; 169: 569-576.
    • (2005) J Cell Biol , vol.169 , pp. 569-576
    • Bennett, C.L.1    Van Rijn, E.2    Jung, S.3    Inaba, K.4    Steinman, R.M.5    Kapsenberg, M.L.6
  • 33
    • 21144444056 scopus 로고    scopus 로고
    • Dynamics and function of Langerhans cells in vivo: Dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells
    • Kissenpfennig A, Henri S, Dubois B, Laplace-Builhe C, Perrin P, Romani N et al. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 2005; 22: 643-654.
    • (2005) Immunity , vol.22 , pp. 643-654
    • Kissenpfennig, A.1    Henri, S.2    Dubois, B.3    Laplace-Builhe, C.4    Perrin, P.5    Romani, N.6
  • 34
    • 28844492624 scopus 로고    scopus 로고
    • Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity
    • Kaplan DH, Jenison MC, Saeland S, Shlomchik WD, Shlomchik MJ. Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 2005; 23: 611-620.
    • (2005) Immunity , vol.23 , pp. 611-620
    • Kaplan, D.H.1    Jenison, M.C.2    Saeland, S.3    Shlomchik, W.D.4    Shlomchik, M.J.5
  • 35
    • 77349125610 scopus 로고    scopus 로고
    • Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10
    • Igyarto BZ, Jenison MC, Dudda JC, Roers A, Muller W, Koni PA et al. Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10. J Immunol 2009; 183: 5085-5093.
    • (2009) J Immunol , vol.183 , pp. 5085-5093
    • Igyarto, B.Z.1    Jenison, M.C.2    Dudda, J.C.3    Roers, A.4    Muller, W.5    Koni, P.A.6
  • 36
    • 55249092998 scopus 로고    scopus 로고
    • Insights into Langerhans cell function from Langerhans cell ablation models
    • Kaplan DH, Kissenpfennig A, Clausen BE. Insights into Langerhans cell function from Langerhans cell ablation models. Eur J Immunol 2008; 38: 2369-2376.
    • (2008) Eur J Immunol , vol.38 , pp. 2369-2376
    • Kaplan, D.H.1    Kissenpfennig, A.2    Clausen, B.E.3
  • 38
    • 65249099085 scopus 로고    scopus 로고
    • Crosspresentation of viral and self antigens by skin-derived CD103+ dendritic cells
    • Bedoui S, Whitney PG, Waithman J, Eidsmo L, Wakim L, Caminschi I et al. Crosspresentation of viral and self antigens by skin-derived CD103+ dendritic cells. Nat Immunol 2009; 10: 488-495.
    • (2009) Nat Immunol , vol.10 , pp. 488-495
    • Bedoui, S.1    Whitney, P.G.2    Waithman, J.3    Eidsmo, L.4    Wakim, L.5    Caminschi, I.6
  • 39
    • 0034327828 scopus 로고    scopus 로고
    • Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes
    • Ruedl C, Koebel P, Bachmann M, Hess M, Karjalainen K. Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes. J Immunol 2000; 165: 4910-4916.
    • (2000) J Immunol , vol.165 , pp. 4910-4916
    • Ruedl, C.1    Koebel, P.2    Bachmann, M.3    Hess, M.4    Karjalainen, K.5
  • 40
    • 0036721329 scopus 로고    scopus 로고
    • Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
    • Kamath AT, Henri S, Battye F, Tough DF, Shortman K. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 2002; 100: 1734-1741.
    • (2002) Blood , vol.100 , pp. 1734-1741
    • Kamath, A.T.1    Henri, S.2    Battye, F.3    Tough, D.F.4    Shortman, K.5
  • 42
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4T cells and stimulate different aspects of cell-mediated immunity
    • Itano AA, McSorley SJ, Reinhardt RL, Ehst BD, Ingulli E, Rudensky AY et al. Distinct dendritic cell populations sequentially present antigen to CD4T cells and stimulate different aspects of cell-mediated immunity. Immunity 2003; 19: 47-57.
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1    McSorley, S.J.2    Reinhardt, R.L.3    Ehst, B.D.4    Ingulli, E.5    Rudensky, A.Y.6
  • 43
    • 55349084353 scopus 로고    scopus 로고
    • Migratory and lymphoidresident dendritic cells cooperate to efficiently prime naive CD4T cells
    • Allenspach EJ, Lemos MP, Porrett PM, Turka LA, Laufer TM. Migratory and lymphoidresident dendritic cells cooperate to efficiently prime naive CD4T cells. Immunity 2008; 29: 795-806.
    • (2008) Immunity , vol.29 , pp. 795-806
    • Allenspach, E.J.1    Lemos, M.P.2    Porrett, P.M.3    Turka, L.A.4    Laufer, T.M.5
  • 44
    • 67649201015 scopus 로고    scopus 로고
    • Glycolipids injected into the skin are presented to NKT cells in the draining lymph node independently of migratory skin dendritic cells
    • Tripp CH, Sparber F, Hermans IF, Romani N, Stoitzner P. Glycolipids injected into the skin are presented to NKT cells in the draining lymph node independently of migratory skin dendritic cells. J Immunol 2009; 182: 7644-7654.
    • (2009) J Immunol , vol.182 , pp. 7644-7654
    • Tripp, C.H.1    Sparber, F.2    Hermans, I.F.3    Romani, N.4    Stoitzner, P.5
  • 45
    • 14044265101 scopus 로고    scopus 로고
    • Cutting edge: Priming of CTL by transcutaneous peptide immunization with imiquimod
    • Rechtsteiner G, Warger T, Osterloh P, Schild H, Radsak MP. Cutting edge: priming of CTL by transcutaneous peptide immunization with imiquimod. J Immunol 2005; 174: 2476-2480.
    • (2005) J Immunol , vol.174 , pp. 2476-2480
    • Rechtsteiner, G.1    Warger, T.2    Osterloh, P.3    Schild, H.4    Radsak, M.P.5
  • 46
    • 22144484148 scopus 로고    scopus 로고
    • Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation
    • Stoitzner P, Tripp CH, Douillard P, Saeland S, Romani N. Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation. J Invest Dermatol 2005; 125: 116-125.
    • (2005) J Invest Dermatol , vol.125 , pp. 116-125
    • Stoitzner, P.1    Tripp, C.H.2    Douillard, P.3    Saeland, S.4    Romani, N.5
  • 47
    • 33847071258 scopus 로고    scopus 로고
    • Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors
    • Le Gal FA, Widmer VM, Dutoit V, Rubio-Godoy V, Schrenzel J, Walker PR et al. Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors. J Invest Dermatol 2007; 127: 622-629.
    • (2007) J Invest Dermatol , vol.127 , pp. 622-629
    • Le Gal, F.A.1    Widmer, V.M.2    Dutoit, V.3    Rubio-Godoy, V.4    Schrenzel, J.5    Walker, P.R.6
  • 48
    • 0037033376 scopus 로고    scopus 로고
    • Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues
    • Campbell DJ, Butcher EC. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 2002; 195: 135-141.
    • (2002) J Exp Med , vol.195 , pp. 135-141
    • Campbell, D.J.1    Butcher, E.C.2
  • 49
    • 1542644156 scopus 로고    scopus 로고
    • Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: Role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets
    • Dudda JC, Simon JC, Martin S. Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets. J Immunol 2004; 172: 857-863.
    • (2004) J Immunol , vol.172 , pp. 857-863
    • Dudda, J.C.1    Simon, J.C.2    Martin, S.3
  • 50
    • 65249150347 scopus 로고    scopus 로고
    • Maintenance of peripheral tolerance through controlled tissue homing of antigenspecific T cells in K14-mOVA mice
    • Bianchi T, Pincus LB, Wurbel MA, Rich BE, Kupper TS, Fuhlbrigge RC et al. Maintenance of peripheral tolerance through controlled tissue homing of antigenspecific T cells in K14-mOVA mice. J Immunol 2009; 182: 4665-4674.
    • (2009) J Immunol , vol.182 , pp. 4665-4674
    • Bianchi, T.1    Pincus, L.B.2    Wurbel, M.A.3    Rich, B.E.4    Kupper, T.S.5    Fuhlbrigge, R.C.6
  • 51
    • 44449128686 scopus 로고    scopus 로고
    • Cutting edge: Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk
    • Chang SY, Cha HR, Igarashi O, Rennert PD, Kissenpfennig A, Malissen B et al. Cutting edge: Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk. J Immunol 2008; 180: 4361-4365.
    • (2008) J Immunol , vol.180 , pp. 4361-4365
    • Chang, S.Y.1    Cha, H.R.2    Igarashi, O.3    Rennert, P.D.4    Kissenpfennig, A.5    Malissen, B.6
  • 52
  • 53
    • 65249092828 scopus 로고    scopus 로고
    • Nanoparticle-based targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice
    • Mahe B, Vogt A, Liard C, Duffy D, Abadie V, Bonduelle O et al. Nanoparticle-based targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice. J Invest Dermatol 2009; 129: 1156-1164.
    • (2009) J Invest Dermatol , vol.129 , pp. 1156-1164
    • Mahe, B.1    Vogt, A.2    Liard, C.3    Duffy, D.4    Abadie, V.5    Bonduelle, O.6
  • 54
    • 0020062280 scopus 로고
    • Depletion of epidermal langerhans cells and Ia immunogenicity from tape-stripped mouse skin
    • Streilein JW, Lonsberry LW, Bergstresser PR. Depletion of epidermal langerhans cells and Ia immunogenicity from tape-stripped mouse skin. J Exp Med 1982; 155: 863-871.
    • (1982) J Exp Med , vol.155 , pp. 863-871
    • Streilein, J.W.1    Lonsberry, L.W.2    Bergstresser, P.R.3
  • 55
    • 2442484432 scopus 로고    scopus 로고
    • A model system using tape stripping for characterization of Langerhans cell-precursors in vivo
    • Holzmann S, Tripp CH, Schmuth M, Janke K, Koch F, Saeland S et al. A model system using tape stripping for characterization of Langerhans cell-precursors in vivo. J Invest Dermatol 2004; 122: 1165-1174.
    • (2004) J Invest Dermatol , vol.122 , pp. 1165-1174
    • Holzmann, S.1    Tripp, C.H.2    Schmuth, M.3    Janke, K.4    Koch, F.5    Saeland, S.6
  • 56
    • 0026706275 scopus 로고
    • Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice
    • Wood LC, Jackson SM, Elias PM, Grunfeld C, Feingold KR. Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 1992; 90: 482-487.
    • (1992) J Clin Invest , vol.90 , pp. 482-487
    • Wood, L.C.1    Jackson, S.M.2    Elias, P.M.3    Grunfeld, C.4    Feingold, K.R.5
  • 57
    • 0028295190 scopus 로고
    • Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin
    • Nickoloff BJ, Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 1994; 30: 535-546.
    • (1994) J Am Acad Dermatol , vol.30 , pp. 535-546
    • Nickoloff, B.J.1    Naidu, Y.2
  • 58
    • 0030748429 scopus 로고    scopus 로고
    • Altered permeability and disordered cutaneous immunoregulatory function in mice with acute barrier disruption
    • Nishijima T, Tokura Y, Imokawa G, Seo N, Furukawa F, Takigawa M. Altered permeability and disordered cutaneous immunoregulatory function in mice with acute barrier disruption. J Invest Dermatol 1997; 109: 175-182.
    • (1997) J Invest Dermatol , vol.109 , pp. 175-182
    • Nishijima, T.1    Tokura, Y.2    Imokawa, G.3    Seo, N.4    Furukawa, F.5    Takigawa, M.6
  • 59
    • 43049154961 scopus 로고    scopus 로고
    • Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch
    • Frerichs DM, Ellingsworth LR, Frech SA, Flyer DC, Villar CP, Yu J et al. Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch. Vaccine 2008; 26: 2782-2787.
    • (2008) Vaccine , vol.26 , pp. 2782-2787
    • Frerichs, D.M.1    Ellingsworth, L.R.2    Frech, S.A.3    Flyer, D.C.4    Villar, C.P.5    Yu, J.6
  • 60
    • 0033782851 scopus 로고    scopus 로고
    • Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice
    • Chen D, Endres RL, Erickson CA, Weis KF, McGregor MW, Kawaoka Y et al. Epidermal immunization by a needle-free powder delivery technology: immunogenicity of influenza vaccine and protection in mice. Nat Med 2000; 6: 1187-1190.
    • (2000) Nat Med , vol.6 , pp. 1187-1190
    • Chen, D.1    Endres, R.L.2    Erickson, C.A.3    Weis, K.F.4    McGregor, M.W.5    Kawaoka, Y.6
  • 61
    • 0036105150 scopus 로고    scopus 로고
    • Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    • Mikszta JA, Alarcon JB, Brittingham JM, Sutter DE, Pettis RJ, Harvey NG. Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery. Nat Med 2002; 8: 415-419.
    • (2002) Nat Med , vol.8 , pp. 415-419
    • Mikszta, J.A.1    Alarcon, J.B.2    Brittingham, J.M.3    Sutter, D.E.4    Pettis, R.J.5    Harvey, N.G.6
  • 62
    • 70349267509 scopus 로고    scopus 로고
    • Development of an ex vivo human skin model for intradermal vaccination: Tissue viability and Langerhans cell behaviour
    • Ng KW, Pearton M, Coulman S, Anstey A, Gateley C, Morrissey A et al. Development of an ex vivo human skin model for intradermal vaccination: tissue viability and Langerhans cell behaviour. Vaccine 2009; 27: 5948-5955.
    • (2009) Vaccine , vol.27 , pp. 5948-5955
    • Ng, K.W.1    Pearton, M.2    Coulman, S.3    Anstey, A.4    Gateley, C.5    Morrissey, A.6
  • 63
    • 32344439794 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocytes by electroporation-enhanced needle-free skin immunization
    • Zhao YL, Murthy SN, Manjili MH, Guan LJ, Sen A, Hui SW. Induction of cytotoxic T-lymphocytes by electroporation-enhanced needle-free skin immunization. Vaccine 2006; 24: 1282-1290.
    • (2006) Vaccine , vol.24 , pp. 1282-1290
    • Zhao, Y.L.1    Murthy, S.N.2    Manjili, M.H.3    Guan, L.J.4    Sen, A.5    Hui, S.W.6
  • 64
    • 0032568114 scopus 로고    scopus 로고
    • Skin immunization made possible by cholera toxin
    • Glenn GM, Rao M, Matyas GR, Alving CR. Skin immunization made possible by cholera toxin. Nature 1998; 391: 851.
    • (1998) Nature , vol.391 , pp. 851
    • Glenn, G.M.1    Rao, M.2    Matyas, G.R.3    Alving, C.R.4
  • 65
    • 0038381565 scopus 로고    scopus 로고
    • Optimization of epicutaneous immunization for the induction of CTL
    • Kahlon R, Hu Y, Orteu CH, Kifayet A, Trudeau JD, Tan R et al. Optimization of epicutaneous immunization for the induction of CTL. Vaccine 2003; 21: 2890-2899.
    • (2003) Vaccine , vol.21 , pp. 2890-2899
    • Kahlon, R.1    Hu, Y.2    Orteu, C.H.3    Kifayet, A.4    Trudeau, J.D.5    Tan, R.6
  • 67
    • 33751566641 scopus 로고    scopus 로고
    • Human Langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria
    • Flacher V, Bouschbacher M, Verronese E, Massacrier C, Sisirak V, Berthier-Vergnes O et al. Human Langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria. J Immunol 2006; 177: 7959-7967.
    • (2006) J Immunol , vol.177 , pp. 7959-7967
    • Flacher, V.1    Bouschbacher, M.2    Verronese, E.3    Massacrier, C.4    Sisirak, V.5    Berthier-Vergnes, O.6
  • 69
    • 33845475904 scopus 로고    scopus 로고
    • Innate immunity mediated by epidermal keratinocytes promotes acquired immunity involving Langerhans cells and T cells in the skin
    • Sugita K, Kabashima K, Atarashi K, Shimauchi T, Kobayashi M, Tokura Y. Innate immunity mediated by epidermal keratinocytes promotes acquired immunity involving Langerhans cells and T cells in the skin. Clin Exp Immunol 2007; 147: 176-183.
    • (2007) Clin Exp Immunol , vol.147 , pp. 176-183
    • Sugita, K.1    Kabashima, K.2    Atarashi, K.3    Shimauchi, T.4    Kobayashi, M.5    Tokura, Y.6
  • 70
    • 0842300069 scopus 로고    scopus 로고
    • Differential expression and function of toll-like receptors in Langerhans cells: Comparison with splenic dendritic cells
    • Mitsui H, Watanabe T, Saeki H, Mori K, Fujita H, Tada Y et al. Differential expression and function of toll-like receptors in Langerhans cells: comparison with splenic dendritic cells. J Invest Dermatol 2004; 122: 95-102.
    • (2004) J Invest Dermatol , vol.122 , pp. 95-102
    • Mitsui, H.1    Watanabe, T.2    Saeki, H.3    Mori, K.4    Fujita, H.5    Tada, Y.6
  • 71
    • 0035881267 scopus 로고    scopus 로고
    • Protective roles of mast cells against enterobacterial infection are mediated by toll-like receptor 4
    • Supajatura V, Ushio H, Nakao A, Okumura K, Ra C, Ogawa H. Protective roles of mast cells against enterobacterial infection are mediated by toll-like receptor 4. J Immunol 2001; 167: 2250-2256.
    • (2001) J Immunol , vol.167 , pp. 2250-2256
    • Supajatura, V.1    Ushio, H.2    Nakao, A.3    Okumura, K.4    Ra, C.5    Ogawa, H.6
  • 72
    • 2942731608 scopus 로고    scopus 로고
    • TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells
    • Matsushima H, Yamada N, Matsue H, Shimada S. TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells. J Immunol 2004; 173: 531-541.
    • (2004) J Immunol , vol.173 , pp. 531-541
    • Matsushima, H.1    Yamada, N.2    Matsue, H.3    Shimada, S.4
  • 75
    • 33845581291 scopus 로고    scopus 로고
    • Toll-like receptor-9 expression induced by tape-stripping triggers on effective immune response with CpG-oligodeoxynucleotides
    • Inoue J, Aramaki Y. Toll-like receptor-9 expression induced by tape-stripping triggers on effective immune response with CpG- oligodeoxynucleotides. Vaccine 2007; 25: 1007-1013.
    • (2007) Vaccine , vol.25 , pp. 1007-1013
    • Inoue, J.1    Aramaki, Y.2
  • 76
    • 33751246180 scopus 로고    scopus 로고
    • Cross-priming with an epicutaneously introduced soluble protein antigen generates Tc1 cells
    • Wang LF, Hsu CJ, Miaw SC, Chiu HC, Liu CY, Yu HS. Cross-priming with an epicutaneously introduced soluble protein antigen generates Tc1 cells. Eur J Immunol 2006; 36: 2904-2911.
    • (2006) Eur J Immunol , vol.36 , pp. 2904-2911
    • Wang, L.F.1    Hsu, C.J.2    Miaw, S.C.3    Chiu, H.C.4    Liu, C.Y.5    Yu, H.S.6
  • 77
    • 0036172532 scopus 로고    scopus 로고
    • Immunization onto bare skin with synthetic peptides: Immunomodulation with a CpG-containing oligodeoxynucleotide and effective priming of influenza virus-specific CD4+ T cells
    • Beignon AS, Briand JP, Muller S, Partidos CD. Immunization onto bare skin with synthetic peptides: immunomodulation with a CpG-containing oligodeoxynucleotide and effective priming of influenza virus-specific CD4+ T cells. Immunology 2002; 105: 204-212.
    • (2002) Immunology , vol.105 , pp. 204-212
    • Beignon, A.S.1    Briand, J.P.2    Muller, S.3    Partidos, C.D.4
  • 78
    • 0034120295 scopus 로고    scopus 로고
    • Imiquimod, a topical immune response modifier, induces migration of Langerhans cells
    • Suzuki H, Wang B, Shivji GM, Toto P, Amerio P, Tomai MA et al. Imiquimod, a topical immune response modifier, induces migration of Langerhans cells. J Invest Dermatol 2000; 114: 135-141.
    • (2000) J Invest Dermatol , vol.114 , pp. 135-141
    • Suzuki, H.1    Wang, B.2    Shivji, G.M.3    Toto, P.4    Amerio, P.5    Tomai, M.A.6
  • 79
    • 34547949557 scopus 로고    scopus 로고
    • Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice
    • Heib V, Becker M, Warger T, Rechtsteiner G, Tertilt C, Klein M et al. Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice. Blood 2007; 110: 946-953.
    • (2007) Blood , vol.110 , pp. 946-953
    • Heib, V.1    Becker, M.2    Warger, T.3    Rechtsteiner, G.4    Tertilt, C.5    Klein, M.6
  • 80
    • 0034541167 scopus 로고    scopus 로고
    • Tumorspecific CD4+ T cells have a major 'post-licensing' role in CTL mediated anti-tumor immunity
    • Marzo AL, Kinnear BF, Lake RA, Frelinger JJ, Collins EJ, Robinson BW et al. Tumorspecific CD4+ T cells have a major 'post-licensing' role in CTL mediated anti-tumor immunity. J Immunol 2000; 165: 6047-6055.
    • (2000) J Immunol , vol.165 , pp. 6047-6055
    • Marzo, A.L.1    Kinnear, B.F.2    Lake, R.A.3    Frelinger, J.J.4    Collins, E.J.5    Robinson, B.W.6
  • 81
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
    • Tacken PJ, de Vries IJ, Torensma R, Figdor CG. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 2007; 7: 790-802.
    • (2007) Nat Rev Immunol , vol.7 , pp. 790-802
    • Tacken, P.J.1    De Vries, I.J.2    Torensma, R.3    Figdor, C.G.4
  • 82
    • 44049103003 scopus 로고    scopus 로고
    • Cutting edge: Langerin/ CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC i and II products in vivo
    • Idoyaga J, Cheong C, Suda K, Suda N, Kim JY, Lee H et al. Cutting edge: langerin/ CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J Immunol 2008; 180: 3647-3650.
    • (2008) J Immunol , vol.180 , pp. 3647-3650
    • Idoyaga, J.1    Cheong, C.2    Suda, K.3    Suda, N.4    Kim, J.Y.5    Lee, H.6
  • 83
    • 33746864909 scopus 로고    scopus 로고
    • Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1
    • Carter RW, Thompson C, Reid DM, Wong SY, Tough DF. Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1. J Immunol 2006; 177: 2276-2284.
    • (2006) J Immunol , vol.177 , pp. 2276-2284
    • Carter, R.W.1    Thompson, C.2    Reid, D.M.3    Wong, S.Y.4    Tough, D.F.5
  • 84
    • 67349242708 scopus 로고    scopus 로고
    • Targeting of epidermal Langerhans cells with antigenic proteins: Attempts to harness their properties for immunotherapy
    • Flacher V, Sparber F, Tripp CH, Romani N, Stoitzner P. Targeting of epidermal Langerhans cells with antigenic proteins: attempts to harness their properties for immunotherapy. Cancer Immunol Immunother 2009; 58: 1137-1147.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1137-1147
    • Flacher, V.1    Sparber, F.2    Tripp, C.H.3    Romani, N.4    Stoitzner, P.5
  • 85
    • 76649115602 scopus 로고    scopus 로고
    • Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis
    • Flacher V, Tripp CH, Stoitzner P, Haid B, Ebner S, Del Frari B et al. Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol 2010; 130: 755-762.
    • (2010) J Invest Dermatol , vol.130 , pp. 755-762
    • Flacher, V.1    Tripp, C.H.2    Stoitzner, P.3    Haid, B.4    Ebner, S.5    Del Frari, B.6
  • 86
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001; 194: 769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3    Guo, M.4    Mahnke, K.5    Rivera, M.6
  • 87
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
    • Bonifaz LC, Bonnyay DP, Charalambous A, Darguste DI, Fujii S, Soares H et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 2004; 199: 815-824.
    • (2004) J Exp Med , vol.199 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3    Darguste, D.I.4    Fujii, S.5    Soares, H.6
  • 88
    • 0029991646 scopus 로고    scopus 로고
    • Epicutaneous exposure of protein antigen induces a predominant Th2-like response with high IgE production in mice
    • Wang LF, Lin JY, Hsieh KH, Lin RH. Epicutaneous exposure of protein antigen induces a predominant Th2-like response with high IgE production in mice. J Immunol 1996; 156: 4077-4082.
    • (1996) J Immunol , vol.156 , pp. 4077-4082
    • Wang, L.F.1    Lin, J.Y.2    Hsieh, K.H.3    Lin, R.H.4
  • 89
    • 0034108370 scopus 로고    scopus 로고
    • Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4
    • Herrick CA, MacLeod H, Glusac E, Tigelaar RE, Bottomly K. Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4. J Clin Invest 2000; 105: 765-775.
    • (2000) J Clin Invest , vol.105 , pp. 765-775
    • Herrick, C.A.1    MacLeod, H.2    Glusac, E.3    Tigelaar, R.E.4    Bottomly, K.5
  • 90
    • 4444342863 scopus 로고    scopus 로고
    • Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response
    • Strid J, Hourihane J, Kimber I, Callard R, Strobel S. Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response. Eur J Immunol 2004; 34: 2100-2109.
    • (2004) Eur J Immunol , vol.34 , pp. 2100-2109
    • Strid, J.1    Hourihane, J.2    Kimber, I.3    Callard, R.4    Strobel, S.5
  • 91
    • 35648935980 scopus 로고    scopus 로고
    • Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge
    • He R, Oyoshi MK, Jin H, Geha RS. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci USA 2007; 104: 15817-15822.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15817-15822
    • He, R.1    Oyoshi, M.K.2    Jin, H.3    Geha, R.S.4
  • 92
    • 32044442305 scopus 로고    scopus 로고
    • Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD4+CD25+ T regulatory cells and is dependent on host-derived IL-10
    • Ghoreishi M, Dutz JP. Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD4+CD25+ T regulatory cells and is dependent on host-derived IL-10. J Immunol 2006; 176: 2635-2644.
    • (2006) J Immunol , vol.176 , pp. 2635-2644
    • Ghoreishi, M.1    Dutz, J.P.2
  • 93
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med 2004; 10: 909-915.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 94
    • 51349093240 scopus 로고    scopus 로고
    • Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells
    • Klechevsky E, Morita R, Liu M, Cao Y, Coquery S, Thompson-Snipes L et al. Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity 2008; 29: 497-510.
    • (2008) Immunity , vol.29 , pp. 497-510
    • Klechevsky, E.1    Morita, R.2    Liu, M.3    Cao, Y.4    Coquery, S.5    Thompson-Snipes, L.6


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