Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells

Immunopharmacology and Immunotoxicology

Volumn 32, Issue 2, 2010, Pages 251-257

  Kim, Do Sung ^a   Jeong, Seul Ki ^b   Kim, Hyung Ryong ^c   Kim, Dal Sik ^a   Chae, Soo Wan ^a   Chae, Han Jung ^a  

^a Chonbuk National University   (South Korea)

^b Chonbuk National University Medical School   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Apoptosis; ER stress; Insulin resistance; Metformin; Palmitate

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INSULIN RECEPTOR SUBSTRATE 1; METFORMIN; PALMITIC ACID; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN HEPG2; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CULTURE TECHNIQUES; CELL SURVIVAL; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNOPRECIPITATION; INSULIN; INSULIN RESISTANCE; LIVER; METFORMIN; MICROSCOPY, FLUORESCENCE; OXIDATIVE STRESS; PALMITIC ACID; PHOSPHORYLATION;

EID: 77952144424     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923970903252220     Document Type: Article

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