Expression and localization of ATP binding cassette transporter A1 (ABCA1) in first trimester and term human placenta

Placenta

Volumn 31, Issue 5, 2010, Pages 423-430

  Bhattacharjee, J ^a   Ietta, F ^a   Giacomello, E ^a   Bechi, N ^a   Romagnoli, R ^a   Fava, A ^b   Paulesu, L ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b Obstetrics and Gynecology Division   (Italy)

Author keywords

ABCA1; Expression; Localization; Placenta; Pregnancy

Indexed keywords

ABC TRANSPORTER A1;

ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTROPHOBLAST; ENDOTHELIUM CELL; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; STROMA CELL; TERM BIRTH; WESTERN BLOTTING;

ADULT; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CHOLESTEROL; CHORIONIC VILLI; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IMMUNOHISTOCHEMISTRY; MATERNAL-FETAL EXCHANGE; MICROSCOPY, CONFOCAL; PREGNANCY; PREGNANCY TRIMESTER, FIRST; RNA, MESSENGER; TERM BIRTH; TROPHOBLASTS;

EID: 77952103942     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2010.02.015     Document Type: Article

References (45)

1. Woollett L.A. Maternal cholesterol in fetal development: transport of cholesterol from the maternal to the fetal circulation. Am J Clin Nutr 82 (2005) 1155-1161
2. Porter J.A., Young K.E., and Beachy P.A. Cholesterol modification of hedgehog signaling proteins in animal development. Science 274 (1996) 255-259
3. Martì E., and Bovolenta P. Sonic hedgehog in CNS development: one signal, multiple outputs. Trends Neurosci 25 (2002) 89-96
4. Cooper M.K., Wassif C.A., Krabowiak P.A., Taipale J., Gong R., Kelley R.I., et al. A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis. Nat Genet 33 (2003) 508-513
5. Kelley R.I. Inborn errors of cholesterol biosynthesis. Adv Pediatr 47 (2000) 1-53
6. Herman G.E. Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes. Hum Mol Genet 12 (2003) R75-R88
7. Napoli C., D'Armiento F.P., Mancini F.P., Postiglione A., Witztum J.L., Palumbo G., et al. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J Clin Invest 100 (1997) 2680-2690
8. McConihay J.A., Horn P.S., and Woollett L.A. Effect of maternal hypercholesterolemia on fetal sterol metabolism in the Golden Syrian hamster. J Lipid Res 42 (2001) 1111-1119
9. Schmid K.E., Davidson W.S., Myatt L., and Woollett L.A. Transport of cholesterol across a BeWo cell monolayer: implications for net transport of sterol from maternal to fetal circulation. J Lipid Res 44 (2003) 1909-1918
10. Yoshida S., and Wada Y. Transfer of maternal cholesterol to embryo and fetus in pregnant mice. J Lipid Res 46 (2005) 2168-2174
11. Wadsack C., Hammer A., Levak-Frank S., Desoye G., Kozarsky K.F., Hirschmugl B., et al. Selective cholesterol ester uptake from high density lipoprotein by human first trimester and villous trophoblast cells. Placenta 24 (2003) 131-143
12. Wyne K.L., and Woollett L.A. Transport of maternal LDL and HDL to the fetal membranes and placenta of the Golden Syrian hamster is mediated by receptor-dependent and receptor-independent processes. J Lipid Res 39 (1998) 518-530
13. Rothblat G.H., de la Llera-Moya M., Atger V., Kellner-Weibel G., Williams D.L., and Phillips M.C. Cell cholesterol efflux: integration of old and new observations provides new insights. J Lipid Res 40 (1999) 781-796
14. Yancey P.G., Bortnick A.E., Kellner-Weibel G., de la Llera-Moya M., Phillips M.C., and Rothblat G.H. Importance of different pathways of cellular cholesterol efflux. Arterioscler Thromb Vasc Biol 23 (2003) 712-719
15. Langmann T., Klucken J., Reil M., Liebisch G., Luciani M.F., Chimini G., et al. Molecular cloning of the human ATP-Binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. Biochem Biophys Res Commun 257 (1999) 29-33
16. Albrecht C., McVey J.H., Elliott J.I., Sardini A., Kasza I., Mumford A.D., et al. A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome. Blood 106 (2005) 542-549
17. Hamon Y., Broccardo C., Chambenoit O., Luciani M.F., Toti F., Chaslin S., et al. ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine. Nat Cell Biol 2 (2000) 399-406
18. Tanc C., Liu Y., Kessler P.S., Vaughan A.M., and Oram J.F. The macrophage cholesterol exporter ABCA1 functions as an anti-inflammatory receptor. J Biol Chem 284 (2009) 32336-32343
19. Yvan-Charvet L., Wang N., and Tall A.R. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. Atherioscler Thromb Vasc Biol 30 (2010) 139-143
20. Adler R.R., Ng A.K., and Rote N.S. Monoclonal antiphosphatidylserine antibody inhibits intercellular fusion of the choriocarcinoma line, JAR. Biol Reprod 53 (1995) 905-910
21. Huppertz B., and Kingdom J.C. Apoptosis in the trophoblast - role of apoptosis in placental morphogenesis. J Soc Gynecol Investig 11 (2004) 353-362
22. Bodzioch M., Orsó E., Klucken J., Langmann T., Böttcher A., Diederich W., et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet 22 (1999) 347-351
23. Marcil M., Brooks-Wilson A., Clee S.M., Roomp K., Zhang L.H., Yu L., et al. Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux. Lancet 354 (1999) 1341-1346
24. Christiansen-Weber T.A., Voland J.R., Wu Y., Ngo K., Roland B.L., Nguyen S., et al. Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency. Am J Pathol 157 (2000) 1017-1029
25. Albrecht C., Soumian S., Tetlow N., Patel P., Sullivan M.H.F., Lakasing L., et al. Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls. Placenta 28 (2007) 701-708
26. Lindegaard M.L., Wassif C.A., Vaisman B., Amar M., Wasmuth E.V., Shamburek R., et al. Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome. Hum Mol Genet 17 (2008) 3806-3813
27. Stefulj J., Panzenboeck U., Becker T., Hirschmugl B., Schweinzer C., Lang I., et al. Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1. Circ Res 104 (2009) 600-608
28. Moore M.K., and Viselli S.M. Staining and quantification of proteins transferred to polyvinylidene fluoride membranes. Anal Biochem 279 (2000) 241-242
29. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) method. Methods 25 (2001) 402-408
30. Pfaffl M.W., Horgan G.W., and Dempfle L. Relative expression tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30 (2002) e36
31. Zhu X., Lee L.Y., Timmins J.M., Brown J.M., Boudyguina E., Mulya A., et al. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances proinflammatory response of macrophages. J Biol Chem 283 (2008) 22930-22941
32. Ietta F, Bechi N, Romagnoli R, Bhattacharjee J, Realacci M, Di Vito M, et-al. 17β-Estradiol modulates the macrophage migration inhibatory factor secretary pathway by regulating ABCA1 expression in human first-trimester placenta. Am J Physiol Endocrinol Metab 2010; 298:E411-8.
33. Reddy S.T., Hama S., Ng C., Grijalva V., Navab M., and Fogelman A.M. ATP-Binding cassette transporter 1 participates in LDL oxidation by artery wall cells. Arterioscler Thromb Vasc Biol 22 (2002) 1877-1883
34. Oram J.F., Mendez A.J., Slotte J.P., and Johnson T.F. High density lipoprotein apolipoproteins mediate removal of sterol from intracellular pools but not from plasma membranes of cholesterol-loaded fibroblasts. Atherosclerosis 11 (1991) 403-414
35. Takahashi Y., and Smith J.D. Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway. Proc Natl Acad Sci U S A 96 (1999) 11358-11363
36. Chen W., Sun Y., Welch C., Gorelik A., Leventhal A.R., Tabas I., et al. Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. J Biol Chem 276 (2001) 43564-43569
37. Azuma Y., Takade M., Shin H.W., Kioka N., Nakayama K., and Ueda K. Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation. Genes Cells 14 (2009) 191-204
38. Jollie W.P. Development, morphology, and function of the yolk-sac placenta of laboratory rodents. Teratology 41 (1990) 361-381
39. Farese Jr. R.V., Cases S., Ruland S.L., Kayden H.J., Wong J.S., Young S.G., et al. A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. J Lipid Res 37 (1996) 347-360
40. Woollett L.A. The origins and roles of cholesterol and fatty acids in the fetus. Curr Opin Lipidol 12 (2001) 305-312
41. Moore K.L., and Persaud T.V.N. Placenta and fetal membranes. Before we are born. Essentials of embryology and birth defects. 5th ed. (1998), WB Saunders Company, Philadelphia, PA
42. Stulc J. Extracellular transport pathways in the haemochorial placenta. Placenta 10 (1989) 113-119
43. Mayhew T.M., Leach L., McGee R., Ismail W.W., Myklebust R., and Lammiman M.J. Proliferation, differentiation and apoptosis in villous trophoblast at 13-41 weeks of gestation (including observations on annulate lamellae and nuclear pore complexes). Placenta 20 (1999) 407-422
44. Zhang E.G., Burton G.J., Smith S.K., and Charnock-Jones D.S. Placental vessel adaptation during gestation and to high altitude: changes in diameter and perivascular cell coverage. Placenta 23 (2002) 751-762
45. Malassine A., Besse C., Roche A., Alsat E., Rebourcet R., Mondon F., et al. 1987 Ultrastructural visualization of the internalization of low density lipoprotein by human placental cells. Histochemistry 87 (1987) 457-464