Effects of catechin, epicatechin and epigallocatechin gallate on testosterone production in rat leydig cells

Journal of Cellular Biochemistry

Volumn 110, Issue 2, 2010, Pages 333-342

  Yu, Po Ling ^a,b   Pu, Hsiao Fung ^b   Chen, Sung Yun ^b   Wang, Shyi Wu ^c   Wang, Paulus S ^a,b  

^a TAIPEI CITY HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Catechin; Epicatechin; Epigallocatechin gallate

Indexed keywords

8 BROMO CYCLIC AMP; 9 (TETRAHYDRO 2 FURYL)ADENINE; CALCIMYCIN; CALCIUM; CATECHIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; CYCLIC AMP; EPICATECHIN; EPIGALLOCATECHIN GALLATE; FORSKOLIN; GONADORELIN; LUTEINIZING HORMONE; NIFEDIPINE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE;

ADENOHYPOPHYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HORMONE SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; LEYDIG CELL; LUTEINIZING HORMONE RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROVOCATION TEST; RAT; STEROIDOGENESIS; STIMULATION; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE RELEASE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CATECHIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LEYDIG CELLS; MALE; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

RATTUS;

EID: 77952082866     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22541     Document Type: Article

References (25)

1. Basu A, Lucas EA. 2007. Mechanisms and effects of green tea on cardiovascular health. Nutr Rev 65:361-375. (Pubitemid 351804352)
2. Chiao YC, Cho WL, Wang PS. 2002. Inhibition of testosterone production by propylthiouracil in rat Leydig cells. Biol Reprod 67:416-422. (Pubitemid 34803923)
3. Chung SY, Landau JM. 2000. Effects of tea consumption on nutrition and health. J Nutr 130:2409-2412.
4. Costa RR, Varanda WA. 2007. Intracellular calcium changes in mice Leydig cells are dependent on calcium entry through T-type calcium channels. J Physiol 585:339-349.
5. Figueiroa MS, César Vieira JS, Leite DS, Filho RC, Ferreira F, Gouveia PS, Udrisar DP, Wanderley MI. 2009. Green tea polyphenols inhibit testosterone production in rat Leydig cells. Asian J Androl 11:362-370.
6. Frei B, Higdon JV. 2003. Antioxidant activity of tea polyphenols in vivo: Evidence from animal studies. J Nutr 133:3275S-3384S.
7. Hara Y, Honda M. 1990. The inhibition of a-amylase by tea polyphenols. Agr Biol Chem 54:1939-1945.
8. Hu MC, Guo IC, Lin JH, Chung BC. 1991. Regulated expression of cytochrome P-450scc (cholesterol-side-chain cleavage enzyme) in cultured cell lines detected by antibody against bacterially expressed human protein. Biochem J 274:813-817.
9. Kao YH, Hiipakka RA, Liao S. 2000. Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. Endocrinology 141:980-987. (Pubitemid 32260441)
10. Kuriyama S, Shimazu T, Ohmori K, Kikuchi N, Nakaya N, Nishino Y, Tsubono Y, Tsuji I. 2006. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: The Ohsaki study. JAMA 296:1255-1265. (Pubitemid 44394897)
11. Lin T, Hu J, Wang D, Stocco DM. 1998. Interferon-gamma inhibited the steroidogenic acute regulatory protein messenger ribonucleic acid expression and protein levels in primary cultures of rat Leydig cells. Endocrinology 139:2217-2222. (Pubitemid 28513739) (Pubitemid 28513739)
12. McFarland KC, Sprengel R, Phillips HS, Köhler M, Rosemblit N, Nikolics K, Segaloff DL, Seeburg PH. 1989. Lutropin-choriogonadotropin receptor: An unusual member of the G protein-coupled receptor family. Science 245:494-499. (Pubitemid 19203999)
13. Monteiro R, Assunção M, Andrade JP, Neves D, Calhau C, Azevedo I. 2008. Chronic green tea consumption decreases body mass, induces aromatase expression, and changes proliferation and apoptosis in adult male rat adipose tissue. J Nutr 138:2156-2163.
14. Mukhtar H, Ahmad N. 1999. Green tea in chemoprevention of cancer. Toxicol Sci 52:111-117.
15. Nomura M, Kaji A, He Z, Ma WY, Miyamoto K, Yang CS, Dong Z. 2001. Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem 276:46624-46631. (Pubitemid 37370925)
16. Satoh K, Sakamoto Y, Ogata A, Nagai F, Mikuriya H, Numazawa M, Yamada K, Aoki N. 2002. Inhibition of aromatase activity by green tea extract catechins and their endocrinological effects of oral administration in rats. Food Chem Toxicol 40:925-933. (Pubitemid 34626700)
17. Shapiro H, Lev S, Cohen J, Singer P. 2009. Polyphenols in the prevention and treatment of sepsis syndromes: Rationale and pre-clinical evidence. Nutrition 25:981-997.
18. Stebbing AR. 2009. Interpreting 'dose-response' curves using homeodynamic data: With an improved explanation for hormesis. Dose Response 7:221-233.
19. Tsai SC, Chiao YC, Lu CC, Doong ML, Chen YH, Shih HC, Liaw C, Wang SW, Wang PS. 1996. Inhibition by amphetamine of testosterone secretion through a mechanism involving an increase of cyclic AMP production in rat testes. Br J Pharmacol 118:984-988. (Pubitemid 26261272)
20. Tsai SC, Chiao YC, Lu CC, Wang PS. 2003. Stimulation of the secretion of luteinizing hormone by ginsenoside-Rb1 in male rats. Chin J Physiol 46:1-7. (Pubitemid 36417073)
21. Wang PS, Tsai SC, Hwang GS, Wang SW, Lu CC, Chen JJ, Liu SR, Lee KY, Chien EJ, Chien CH, Lee HY, Lau CP, Tsai CL. 1994. Calcitonin inhibits testosterone and luteinizing hormone secretion through a mechanism involving an increase in cAMP production in rats. J Bone Miner Res 9:1583-1590.
22. Wu AH, Arakawa K, Stanczyk FZ, Van Den Berg D, Koh WP, Yu MC. 2005. Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore. Carcinogenesis 26:976-980. (Pubitemid 41214327)
23. Yang CS, Chung JY, Yang G, Chhabra SK, Lee MJ. 2000. Tea and tea polyphenols in cancer prevention. J Nutr 130:472S-478S.
24. Yang CS, Wang X, Lu G, Picinich SC. 2009. Cancer prevention by tea: Animal studies, molecular mechanisms and human relevance. Nat Rev Cancer 9:429-439.
25. Yu PL, Chao HL, Wang SW, Wang PS. 2009. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by Zona fasciculata-reticularis cells in male rats. J Cell Biochem 108:469-475.