Interpreting 'dose-response' curves using homeodynamic data: With an improved explanation for hormesis

Dose-Response

Volumn 7, Issue 3, 2009, Pages 221-233

  Stebbing, A R D ^a  

^a PLYMOUTH MARINE LABORATORY   (United Kingdom)

Author keywords

Acquired tolerance; Control mechanism; Homeodynamic; Hormesis; curve; curve

Indexed keywords

EID: 70349570863     PISSN: None     EISSN: 15593258     Source Type: Journal    
DOI: 10.2203/dose-response.08-020.stebbing     Document Type: Article

References (24)

1. Ashby WR. 1958. Requisite variety and its implications for the control of complex systems. Cybernetica 1: 8399
2. Ashby WR. 1960. Design for a Brain. Chapman and Hall, London
3. Calabrese EJ. 1999. Evidence that hormesis represents an "overcompensation" response to a disruption in homeostasis. Ecotoxicol Environ Safe 42: 135137
4. Calabrese EJ. 2005a. Hormetic dose-response relationships in immunology: occurrence, quantitative features of dose-reponse, mechanistic foundations and clinical implications. Crit Rev Toxicol, 35(2-3): 89-295.
5. Calabrese EJ. 2005b. Cancer biology and hormesis: human tumpur cell lines commonly display hormetic (biphasic) dose-responses. Crit Rev Toxicol, 35:463-582.
6. Calabrese EJ. Baldwin LA. 1997. A quantitatively based methodology for the evaluation of chemical hormesis. Hum Ecol Risk Assess, 3(4): 545-554.
7. Calabrese EJ. Baldwin LA. 2000. Special issue on hormesis. Hum Exp Toxicol 19(1): 2-97
8. Calabrese EJ. Baldwin LA. 2001. Scientific foundations of hormesis. Special Issue. Crit Rev Toxicol, 31 (4-5): 349-681.
9. Calabrese EJ Baldwin LA. 2003. Toxicology rethinks its central belief. Nature 421: 691692
10. Schmidt-Nielsen K. 1979. Animal Physiology. Adaptation and environment. Cambridge University Press, Cambridge.
11. Stebbing ARD. 1976. The effects of low meal levels on a clonal hydroid. J Marine Biol Assoc UK 56: 977994
12. Stebbing ARD. 1981a. The kinetics of growth control in a colonial hydroid. J Marine Biol Assoc UK 61: 3563
13. Stebbing ARD. 1981b. Hormesis - stimulation of colony growth in Campanularia flexuosa (Hydrozoa) by copper, cadmium and other toxicants. Aquatic Toxicol, 1: 227238
14. Stebbing ARD. 1981c. The effects of reduced salinity on colonial growth and membership in a hydroid. J Exp Marine Biol Ecol, 55: 233241
15. Stebbing ARD. 1982. Hormesis - the stimulation of growth by low levels of inhibitors. Sci Total Environ, 22: 213234
16. Stebbing ARD. 1998. A theory for growth hormesis. Mut Res, 403: 249258
17. Stebbing ARD. 2000. Hormesis: interpreting the β-curve using control theory. J Appl Toxicol, 20: 93101
18. Stebbing ARD. 2003. Adaptive responses account for the β-curve- hormesis is linked to acquired tolerance. Non-linearity Biol Toxicol Med, 1: 493511
19. Stebbing ARD. Cleary JJ. Brinsley M. Goodchild C. Santiago-Fandiño V. 1983. Responses of a hydroid to surface water samples in the River Tamar and Plymouth Sound in relation to metal concentration. J Marine Biol Assoc UK, 63: 695711
20. Stebbing ARD. Norton JP. Brinsley M. D. 1984. Dynamics of growth control in a marine yeast subject to perturbation. J Gen Microbiol, 130: 17991808
21. Stebbing ARD. Pomroy AJ. 1978. A sublethal technique for assessing the effects of contaminants using Hydra littoralis. Wat Res, 12:631-635.
22. Teigen KH. 1994. Yerkes-Dodson: a law for all seasons. Theor Psychol, 4(4): 525-547
23. Townsend JF. Luckey TD. 1960. Hormoligosis in pharmacology. JAMA, 173: 4448
24. Yerkes RM. Dodson JD. 1908. The relation of strength of stimulus to rapidity of habit-formation. J Comp Neurol Psychol, 18: 459482