메뉴 건너뛰기




Volumn 11, Issue 3, 2009, Pages 362-370

Green tea polyphenols inhibit testosterone production in rat Leydig cells

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; ANDROSTENEDIONE; CHORIONIC GONADOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPICATECHIN; EPIGALLOCATECHIN GALLATE; GONADORELIN; GREEN TEA EXTRACT; PROTEIN KINASE C ACTIVATOR; TESTOSTERONE; FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; PROTEIN KINASE C;

EID: 69249217971     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2009.2     Document Type: Article
Times cited : (39)

References (41)
  • 2
    • 0027492737 scopus 로고
    • Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures
    • Morel I, Lescoat G, Cogrel P, Sergent O, Pasdeloup N, et al. Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures. Biochem Pharmacol 1993; 45: 13-9.
    • (1993) Biochem Pharmacol , vol.45 , pp. 13-19
    • Morel, I.1    Lescoat, G.2    Cogrel, P.3    Sergent, O.4    Pasdeloup, N.5
  • 3
    • 0030582664 scopus 로고    scopus 로고
    • Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes
    • Guo Q, Zhao B, Li M, Shen S, Xin W. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1996; 1304: 210-22.
    • (1996) Biochim Biophys Acta , vol.1304 , pp. 210-222
    • Guo, Q.1    Zhao, B.2    Li, M.3    Shen, S.4    Xin, W.5
  • 4
    • 0036285967 scopus 로고    scopus 로고
    • Inhibition of aromatase activity by green tea extract catechins and their endocrinological effects of oral administration in rats
    • Satoh K, Sakamoto Y, Ogata A, Nagai F, Mikuriya H, et al. Inhibition of aromatase activity by green tea extract catechins and their endocrinological effects of oral administration in rats. Food Chem Toxicol 2002; 40: 925-33.
    • (2002) Food Chem Toxicol , vol.40 , pp. 925-933
    • Satoh, K.1    Sakamoto, Y.2    Ogata, A.3    Nagai, F.4    Mikuriya, H.5
  • 5
    • 0345410331 scopus 로고    scopus 로고
    • Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse
    • Goodin MG, Rosegren RJ. Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. Toxicol Sci 2003; 76: 262-70.
    • (2003) Toxicol Sci , vol.76 , pp. 262-270
    • Goodin, M.G.1    Rosegren, R.J.2
  • 6
    • 31044449456 scopus 로고    scopus 로고
    • Inhibition of angiotensin converting enzyme activity by flavanol-rich foods
    • Actis-Goretta L, Ottaviani JI, Fraga CG. Inhibition of angiotensin converting enzyme activity by flavanol-rich foods. J Agirc Food Chem 2006; 54: 229-34.
    • (2006) J Agirc Food Chem , vol.54 , pp. 229-234
    • Actis-Goretta, L.1    Ottaviani, J.I.2    Fraga, C.G.3
  • 7
    • 0030049841 scopus 로고    scopus 로고
    • Inhibition of thyroid peroxidase by dietary flavonoids
    • Divi RL, Doerge DR. Inhibition of thyroid peroxidase by dietary flavonoids. Chem Res Toxicol 1996; 9: 16-23.
    • (1996) Chem Res Toxicol , vol.9 , pp. 16-23
    • Divi, R.L.1    Doerge, D.R.2
  • 8
    • 0032945173 scopus 로고    scopus 로고
    • Green tea polyphenols and cancer: Biologic mechanisms and practical implications
    • Ahmad N, Mukhtar H. Green tea polyphenols and cancer: Biologic mechanisms and practical implications. Nutr Rev 1999; 57: 78-83.
    • (1999) Nutr Rev , vol.57 , pp. 78-83
    • Ahmad, N.1    Mukhtar, H.2
  • 9
    • 0031020769 scopus 로고    scopus 로고
    • Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells
    • Ripple MO, Henry WF, Rago RP, Wilding G. Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells. J Natl Cancer Inst 1997; 89: 40-8.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 40-48
    • Ripple, M.O.1    Henry, W.F.2    Rago, R.P.3    Wilding, G.4
  • 10
    • 0031867690 scopus 로고    scopus 로고
    • Diet, nutrition, and prostate cancer
    • Clinton SK, Giovannucci E. Diet, nutrition, and prostate cancer. Ann Rev Nutr 1998; 18: 413-40.
    • (1998) Ann Rev Nutr , vol.18 , pp. 413-440
    • Clinton, S.K.1    Giovannucci, E.2
  • 11
    • 0035467993 scopus 로고    scopus 로고
    • Global cancer statistics in the year 2000
    • Parkin DM. Global cancer statistics in the year 2000. Lancet Oncol 2001; 2: 533-43.
    • (2001) Lancet Oncol , vol.2 , pp. 533-543
    • Parkin, D.M.1
  • 12
    • 0029124096 scopus 로고
    • Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate
    • Liao S, Umekita Y, Guo J, Kokontis JM, Hiipakka RA. Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett 1995; 96: 239-43.
    • (1995) Cancer Lett , vol.96 , pp. 239-243
    • Liao, S.1    Umekita, Y.2    Guo, J.3    Kokontis, J.M.4    Hiipakka, R.A.5
  • 13
    • 0034465753 scopus 로고    scopus 로고
    • Modulation of endocrine systems and food intake by green tea epigallocatechin gallate
    • Kao YH, Hiipakka RA, Liao S. Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. Endocrinology 2000; 141: 980-7.
    • (2000) Endocrinology , vol.141 , pp. 980-987
    • Kao, Y.H.1    Hiipakka, R.A.2    Liao, S.3
  • 14
    • 0020401109 scopus 로고
    • Luteinizing hormone receptors and gonadotropic activation of purified rat Leydig cells
    • Dehejia A, Nozu K, Catt KJ, Dufau ML. Luteinizing hormone receptors and gonadotropic activation of purified rat Leydig cells. J Biol Chem 1982; 257: 13781-6.
    • (1982) J Biol Chem , vol.257 , pp. 13781-13786
    • Dehejia, A.1    Nozu, K.2    Catt, K.J.3    Dufau, M.L.4
  • 15
    • 0029844581 scopus 로고    scopus 로고
    • Pretreatment with phorbol ester and an LHRH agonist reduces testosterone production and protein kinase C activity in rat Leydig cells challenged with PDBu and LHRH
    • Wanderley MI, Negro-Vilar A. Pretreatment with phorbol ester and an LHRH agonist reduces testosterone production and protein kinase C activity in rat Leydig cells challenged with PDBu and LHRH. Braz J Med Biol Res 1996; 29: 1557-65.
    • (1996) Braz J Med Biol Res , vol.29 , pp. 1557-1565
    • Wanderley, M.I.1    Negro-Vilar, A.2
  • 16
    • 0036780991 scopus 로고    scopus 로고
    • Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways
    • Lin JK. Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways. Arch Pharm Res 2002; 25: 561-71.
    • (2002) Arch Pharm Res , vol.25 , pp. 561-571
    • Lin, J.K.1
  • 17
    • 0038661168 scopus 로고    scopus 로고
    • Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate
    • Levites Y, Amit T, Mandel S, Youdim MB. Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J 2003; 17: 952-4.
    • (2003) FASEB J , vol.17 , pp. 952-954
    • Levites, Y.1    Amit, T.2    Mandel, S.3    Youdim, M.B.4
  • 18
    • 1242294387 scopus 로고    scopus 로고
    • A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation
    • Lorenz M, Wessler S, Follmann E, Michaelis W, Dusterhoft T, et al. A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation. J Biol Chem 2004; 279: 6190-5.
    • (2004) J Biol Chem , vol.279 , pp. 6190-6195
    • Lorenz, M.1    Wessler, S.2    Follmann, E.3    Michaelis, W.4    Dusterhoft, T.5
  • 19
    • 0026575898 scopus 로고
    • Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-Otetradecanoylphorbol-13-acetate in the skin of SKH-1 mice
    • Wang ZY, Huang MT, Ferraro T, Wong CQ, Lou YR, et al. Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-Otetradecanoylphorbol-13-acetate in the skin of SKH-1 mice. Cancer Res 1992; 52: 1162-70.
    • (1992) Cancer Res , vol.52 , pp. 1162-1170
    • Wang, Z.Y.1    Huang, M.T.2    Ferraro, T.3    Wong, C.Q.4    Lou, Y.R.5
  • 20
    • 0022850688 scopus 로고
    • Monoclonal antibodies against rat Leydig cell surface antigens
    • Hedger MP, Eddy EM. Monoclonal antibodies against rat Leydig cell surface antigens. Biol Reprod 1986; 35: 1309-19.
    • (1986) Biol Reprod , vol.35 , pp. 1309-1319
    • Hedger, M.P.1    Eddy, E.M.2
  • 21
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 22
    • 24644490030 scopus 로고    scopus 로고
    • Reduction of MTT by flavonoids in the absence of cells
    • Peng L, Wang B, Ren P. Reduction of MTT by flavonoids in the absence of cells. Colloids Surf B Biointerfaces 2005; 45: 108-11.
    • (2005) Colloids Surf B Biointerfaces , vol.45 , pp. 108-111
    • Peng, L.1    Wang, B.2    Ren, P.3
  • 23
    • 1642325138 scopus 로고    scopus 로고
    • Inhibitory effects of green tea polyphenols on the production of a virulence factor of the periodontal-disease-causing anaerobic bacterium Porphyromonas gingivalis
    • Sakanaka S, Okada Y. Inhibitory effects of green tea polyphenols on the production of a virulence factor of the periodontal-disease-causing anaerobic bacterium Porphyromonas gingivalis. J Agric Food Chem 2004; 52: 1688-92.
    • (2004) J Agric Food Chem , vol.52 , pp. 1688-1692
    • Sakanaka, S.1    Okada, Y.2
  • 24
    • 0016462675 scopus 로고
    • Use of specific antibodies for quantification of steroid hormones
    • O'Malley BW, Hardman JG, editors, New York: Academic Press Inc
    • Niswender GD, Akbar AM, Nett TM. Use of specific antibodies for quantification of steroid hormones. In: O'Malley BW, Hardman JG, editors. Methods in Enzymology. New York: Academic Press Inc.; 1975. p 16-34.
    • (1975) Methods in Enzymology , pp. 16-34
    • Niswender, G.D.1    Akbar, A.M.2    Nett, T.M.3
  • 25
    • 0026649978 scopus 로고
    • Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: Regulation by a mitochondrial diazepam binding inhibitor receptor
    • Papapadopoulos V, Guarneri P, Krueger KE, Guidotti A, Costa E. Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: Regulation by a mitochondrial diazepam binding inhibitor receptor. Proc Natl Acad Sci USA 1992; 89: 5113-7.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5113-5117
    • Papapadopoulos, V.1    Guarneri, P.2    Krueger, K.E.3    Guidotti, A.4    Costa, E.5
  • 26
    • 33747877987 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate (EGCG): Chemical and biomedical perspectives
    • Nagle DG, Ferreira D, Zhou YD. Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives. Phytochemistry 2006; 67: 1849-55.
    • (2006) Phytochemistry , vol.67 , pp. 1849-1855
    • Nagle, D.G.1    Ferreira, D.2    Zhou, Y.D.3
  • 27
    • 0037163110 scopus 로고    scopus 로고
    • Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y, Amit T, Youdim MB, Mandel S. Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J Biol Chem 2002; 277: 30574-80.
    • (2002) J Biol Chem , vol.277 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Youdim, M.B.3    Mandel, S.4
  • 28
    • 0035918278 scopus 로고    scopus 로고
    • Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
    • Nam S, Smith DM, Dou QP. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem 2001; 276: 13322-30.
    • (2001) J Biol Chem , vol.276 , pp. 13322-13330
    • Nam, S.1    Smith, D.M.2    Dou, Q.P.3
  • 29
    • 0037087689 scopus 로고    scopus 로고
    • Structure-activity relationships for inhibition of human 5alphareductases by polyphenols
    • Hiipakka RA, Zhang HZ, Dai W, Dai Q, Liao S. Structure-activity relationships for inhibition of human 5alphareductases by polyphenols. Biochem Pharmacol 2002; 63: 1165-76.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1165-1176
    • Hiipakka, R.A.1    Zhang, H.Z.2    Dai, W.3    Dai, Q.4    Liao, S.5
  • 30
    • 22144448203 scopus 로고    scopus 로고
    • Trapping of growth factors by catechins: A possible therapeutical target for prevention of proliferative diseases
    • Doss MX, Potta SP, Hescheler J, Sachinidis A. Trapping of growth factors by catechins: A possible therapeutical target for prevention of proliferative diseases. J Nutr Biochem 2005; 16: 259-66.
    • (2005) J Nutr Biochem , vol.16 , pp. 259-266
    • Doss, M.X.1    Potta, S.P.2    Hescheler, J.3    Sachinidis, A.4
  • 31
    • 59449089120 scopus 로고    scopus 로고
    • Gonadotrophin-releasing hormone-I and -II stimulate steroidogenesis in prepubertal murine Leydig cells in vitro
    • Lin YM, Liu MY, Poon SL, Leu SF, Huang BM. Gonadotrophin-releasing hormone-I and -II stimulate steroidogenesis in prepubertal murine Leydig cells in vitro. Asian J Androl 2008; 10:929-36.
    • (2008) Asian J Androl , vol.10 , pp. 929-936
    • Lin, Y.M.1    Liu, M.Y.2    Poon, S.L.3    Leu, S.F.4    Huang, B.M.5
  • 32
    • 0033796721 scopus 로고    scopus 로고
    • Regulation of Leydig cell steroidogenic function during aging
    • Zirkin BR, Chen H. Regulation of Leydig cell steroidogenic function during aging. Biol Reprod 2000; 63: 977-98.
    • (2000) Biol Reprod , vol.63 , pp. 977-998
    • Zirkin, B.R.1    Chen, H.2
  • 33
    • 0002038268 scopus 로고    scopus 로고
    • Structure, function and regulation of steroidogenic enzymes in the Leydig cell
    • Payne AH, Hardy MP, Russel LD, editors, Vienna, IL: Cache River Press;
    • Payne AH, O'Shaughnessy PJ. Structure, function and regulation of steroidogenic enzymes in the Leydig cell. In: Payne AH, Hardy MP, Russel LD, editors. The Leydig Cell. Vienna, IL: Cache River Press; 1996. p 259-86.
    • (1996) The Leydig Cell , pp. 259-286
    • Payne, A.H.1    O'Shaughnessy, P.J.2
  • 34
    • 0033233309 scopus 로고    scopus 로고
    • Wong CK, Keung WM. Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1.145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): Characterization and its inhibition by isoflavones. J Steroid Biochem Mol Biol 1999; 71: 191-202.
    • Wong CK, Keung WM. Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1.145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): Characterization and its inhibition by isoflavones. J Steroid Biochem Mol Biol 1999; 71: 191-202.
  • 35
    • 0034712219 scopus 로고    scopus 로고
    • Effects of phytoestrogens on aromatase, 3beta and 17betahydroxysteroid dehydrogenase activities and human breast cancer cells
    • Le Bail JC, Champavier Y, Chulia AJ, Habrioux G. Effects of phytoestrogens on aromatase, 3beta and 17betahydroxysteroid dehydrogenase activities and human breast cancer cells. Life Sci 2000; 66: 1281-91.
    • (2000) Life Sci , vol.66 , pp. 1281-1291
    • Le Bail, J.C.1    Champavier, Y.2    Chulia, A.J.3    Habrioux, G.4
  • 36
    • 0035931322 scopus 로고    scopus 로고
    • Phytoestrogens inhibit human 17beta-hydroxysteroid dehydrogenase type 5
    • Krazeisen A, Breitling R, Möller G, Adamski J. Phytoestrogens inhibit human 17beta-hydroxysteroid dehydrogenase type 5. Mol Cell Endocrinol 2001; 171: 151-62.
    • (2001) Mol Cell Endocrinol , vol.171 , pp. 151-162
    • Krazeisen, A.1    Breitling, R.2    Möller, G.3    Adamski, J.4
  • 37
    • 0036231186 scopus 로고    scopus 로고
    • Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells
    • Ohno S, Shinoda S, Toyoshima S, Nakazawa H, Makino T, et al. Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells. J Steroid Biochem Mol Biol 2002; 80: 355-63.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 355-363
    • Ohno, S.1    Shinoda, S.2    Toyoshima, S.3    Nakazawa, H.4    Makino, T.5
  • 38
    • 23144467911 scopus 로고    scopus 로고
    • Dose-response effects of phytoestrogens on the activity and expression of 3beta-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells
    • Lacey M, Bohday J, Fonseka SM, Ullah AI, Whitehead SA. Dose-response effects of phytoestrogens on the activity and expression of 3beta-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells. J Steroid Biochem Mol Biol 2005; 96: 279-86.
    • (2005) J Steroid Biochem Mol Biol , vol.96 , pp. 279-286
    • Lacey, M.1    Bohday, J.2    Fonseka, S.M.3    Ullah, A.I.4    Whitehead, S.A.5
  • 39
    • 30444435041 scopus 로고    scopus 로고
    • Effects of extracts from Hibiscus macranthus and Basella alba mixture on testosterone production in vitro adult rat testes slices
    • Moundipa PF, Ngouela S, Kamtchouing P, Tsamo E, Tchouanguep FM, et al Effects of extracts from Hibiscus macranthus and Basella alba mixture on testosterone production in vitro adult rat testes slices. Asian J Androl 2006; 8: 111-4.
    • (2006) Asian J Androl , vol.8 , pp. 111-114
    • Moundipa, P.F.1    Ngouela, S.2    Kamtchouing, P.3    Tsamo, E.4    Tchouanguep, F.M.5
  • 40
    • 45849101302 scopus 로고    scopus 로고
    • The inhibitory effects on adult male reproductive functions of crude garlic (Allium sativum) feeding
    • Hammami I, Nahdi A, Mauduit C, Benahmed M, Amri M, et al. The inhibitory effects on adult male reproductive functions of crude garlic (Allium sativum) feeding. Asian J Androl 2008; 10: 593-601.
    • (2008) Asian J Androl , vol.10 , pp. 593-601
    • Hammami, I.1    Nahdi, A.2    Mauduit, C.3    Benahmed, M.4    Amri, M.5
  • 41
    • 14744275870 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate from green tea negatively affects swine granulosa cell function
    • Basini G, Bianco F, Grasselli F. Epigallocatechin-3-gallate from green tea negatively affects swine granulosa cell function. Domest Anim Endocrinol 2005; 28: 243-56.
    • (2005) Domest Anim Endocrinol , vol.28 , pp. 243-256
    • Basini, G.1    Bianco, F.2    Grasselli, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.