The influence of raw and processed garlic and onions on plasma classical and non-classical atherosclerosis indices: Investigations in vitro and in vivo

Phytotherapy Research

Volumn 24, Issue 5, 2010, Pages 706-714

  Gorinstein, Shela ^a   Leontowicz, Hanna ^b   Leontowicz, Maria ^b   Jastrzebski, Zenon ^c   Najman, Katarzyna ^b   Tashma, Zev ^a   Katrich, Elena ^a   Heo, Buk Gu ^d   Cho, Ja Yong ^e   Park, Yun Jum ^f   Trakhtenberg, Simon ^g  

^a HEBREW UNIVERSITY   (Israel)

^b WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^c NATIONAL MEDICINES INSTITUTE   (Poland)

^d Naju Foundation of Natural Dyeing Culture   (South Korea)

^e Jeonnam Provincial College   (South Korea)

^f Wonkwang University   (South Korea)

^g KAPLAN MEDICAL CENTER   (Israel)

Author keywords

Antioxidants; CRP; Plasma lipids; Rats; Transaminases; Vegetables

Indexed keywords

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL DIET; CONTROLLED STUDY; GARLIC; HISTOPATHOLOGY; MALE; NONHUMAN; ONION; RAT;

ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; CHOLESTEROL, DIETARY; DIET, ATHEROGENIC; FOOD HANDLING; GARLIC; LIPIDS; MALE; ONIONS; RATS; RATS, WISTAR;

ALLIUM ATRORUBENS; ALLIUM CEPA; ALLIUM SATIVUM; RATTUS; RATTUS NORVEGICUS;

EID: 77952060810     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3001     Document Type: Article

References (42)

1. Akila M, Devaraj H. 2008. Synergistic effect of tincture of Crataegus and Mangifera indica L. extract on hyperlipidemic and antioxidant status in atherogenic rats. Vascul Pharmacol 49: 173-177.
2. Baluchnejadmojarad T, Roghani M. 2003. Garlic extract attenuates time-dependent changes in the reactivity of isolated aorta in streptozotocin-diabetic rats. Life Sci 73: 2281-2289. (Pubitemid 36980825)
3. Campos KE, Diniz YS, Cataneo AC, Faine LA, Alves MJQF, Novelli ELB. 2003. Hypoglycemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats. Int J Food Sci Nutr 54: 241-246.
4. Choi Y, Lee SM, Chun J, Lee HB, Lee J. 2006. Influence of heat treatment on the antioxidant activities and polyphenolic compounds of Shiitake (Lentinus edodes) mushroom. Food Chem 99: 381-387. (Pubitemid 44294481)
5. Corzo-Martínez M, Corzo N, Villamiel M. 2007. Biological properties of onions and garlic. Trends Food Sci Technol 18: 609-625.
6. Dallongeville J, Hercberg S, Amouyel P, Dauchet LA. 2006. Fruit and consumption and risk of coronary heart disease: A meta-analysis of cohort studies. J Nutr 136: 2588-2593. (Pubitemid 44521618)
7. Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, Lowe GDO, Pepys MB, Gudnason V. 2004. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. New Engl J Med 350: 1387-1397. (Pubitemid 38419992)
8. Deepa PR, Varalakshmi P. 2005. Atheroprotective effect of exogenous heparin-derivative treatment on the aortic disturbances and lipoprotein oxidation in hypercholesterolemic diet fed rats. Clin Chim Acta 355: 119-130. (Pubitemid 40501139)
9. Dembitsky VM, Abu-Lafi S, Hanus LO. 2007. Occurrence of sulfur- containing fatty acids in Allium sativum. Natural Product Communications 2: 771-774.
10. Faller ALK, Fialho E. 2009. The antioxidant capacity and polyphenol content of organic and conventional retail vegetables after domestic cooking. Food Res Intern 42: 210-215.
11. Geyas F, Young E, Blankenship SM, McFeeters RF. 1996. Dietary fiber composition of stark spur supreme delicious apple fruit as influenced by rootstock and growing region. Fruit Varieties J 1: 35-41. (Pubitemid 26263155)
12. Gorinstein S, Leontowicz H, Leontowicz M, Drzewiecki J, Najman K, Katrich E, Barasch D, Yamamoto K, Trakhtenberg S. 2006. Raw and boiled garlic enhances plasma antioxidant activity and improves plasma lipid metabolism in cholesterol-fed rats. Life Sci 78: 660-666.
13. Gorinstein S, Leontowicz H, Leontowicz M, Namiesnik J, Najman K, Drzewiecki J, Cvikrova M, Martincova O, Katrich E, Trakhtenberg S. 2008. Comparison of the main bioactive compounds and antioxidant activities in garlic and white and red onions after treatment protocols. J Agric Food Chem 56: 4418-4426. (Pubitemid 351999364)
14. Gorinstein S, Park YS, Heo BG, Namiesnik J, Leontowicz H, Leontowicz M, Ham KS, Cho JY, Kang SG. 2009. A comparative study of phenolic compounds and antioxidant and antiproliferative activities in frequently consumed raw vegetables. Eur Food Res Technol 228: 903-911.
15. Halvorsen BL, Carlsen MH, Phillips KM, Bøhn SK, Holte K, Jacobs DR, Blomhoff R. 2006. Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr 84: 95-135. (Pubitemid 44699176)
16. Ioannou GN, Weiss NS, Boyko EJ, Mozaffarian D, Lee SP. 2006. Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States. Hepatology 43: 1145-1151. (Pubitemid 43724639)
17. Kain K, Carter AM, Grant PJ, Scott EM. 2008. Alanine amino-transferase is associated with athero- thrombotic risk factors in a British South Asian population. J Throm Haemost 6: 737-741. (Pubitemid 351524531)
18. Kawamoto E, Sakai Y, Okamura Y, Yamamoto Y. 2004. Effects of boiling on the antihypertensive and antioxidant activities of onion. J Nutr Sci Vitaminol 50: 171-176. (Pubitemid 39045119)
19. Knai C, Pomerleau J, Lock K, McKee M. 2006. Getting children to eat more fruit and vegetables: A systematic review. Prev Med 42: 85-95. (Pubitemid 43210373)
20. Kung-chi Chan, Mei-chin Yin, Wan-ju Chao. 2007. Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats. Food Chem Toxicol 45: 502-507.
21. Kwon M-J, Song Y-S, Choi M-S, Park S-J, Jeong K-S, Song Y-O. 2003. Cholesteryl ester transfer protein activity and atherogenic parameters in rabbits supplemented with cholesterol and garlic powder. Life Sci 72: 2953-2964.
22. Liu C-T, Sheen L-Y, Lii C-K. 2007. Does garlic have a role as an antidiabetic agent? Review. Mol Nutr Food Res 51: 1353-1364.
23. Leontowicz H, Leontowicz M, Haruenkit R, Poovarodom S, Jastrzebski Z, Drzewiecki J, Martinez Ayala AL, Jesion I, Trakhtenberg S, Gorinstein, S. 2008. Durian (Durio zibethinus Murr.) cultivars as nutritional supplementation to rat's diets. Food Chem Toxicol 46: 581-589.
24. Lotito SB, Frei B. 2004. Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects. Free Rad Biol Med 36: 201-211. (Pubitemid 38117238)
25. Mahfouz MM, Kummerow FA. 2000. Cholesterol-rich diets have different effects on lipid peroxidation, cholesterol oxides, and antioxidant enzymes in rats and rabbits. J Nutr Biochem 11: 293-302.
26. Martinez-Gonzalez MA, Fernandez-Jarne E, Martinez-Losa E, Prado-Santamaria M, Brugarolas-Brufau C, Serrano- Martinez M. 2002. Role of fiber and fruits in the Mediterranean diet to protect against myocardial infarction: a case-control study in Spain. Eur J Clin Nutr 56: 715-722.
27. Nicoli MC, Anese M, Parpinel M. 1999. Influence of processing on the antioxidant properties of fruit and vegetables. Trends Food Sci Technol 10: 94-100. (Pubitemid 29449711)
28. Omar SH, Abshar UH, Nehal M. 2007. Anticarcinogenic and antitumorigenic effect of garlic and factors affecting its activity: a review. Pharmacognosy Reviews 1: 215-221.
29. Ou B, Huang D, Hampsch-Woodill M, Flanagan J, Deemer E. 2002. Analysis of antioxidant activities of common vegetables employing oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) assays: a comparative study. J Agric Food Chem 50: 3122-3128. (Pubitemid 34533610)
30. Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. 2002. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Rad Res 36: 217-233.
31. Randhir R, Kwon YI, Shetty K. 2008. Effect of thermal processing on phenolics, antioxidant activity and health-relevant functionality of select grain sprouts and seedlings. Inter Food Sci Emerg Technol 9: 355-364.
32. Ridker PM. 2003. Clinical application of C-Reactive Protein for cardiovascular disease detection and prevention. Circulation 107: 363-369. (Pubitemid 36158034)
33. Sahlin E, Savage GP, Lister CE. 2004. Investigation of the antioxidant properties of tomatoes after processing. J Food Comp Anal 17: 635-647. (Pubitemid 38979528)
34. Schindhelm R, Dekker J, Nijpels G, Bouter L, Stehouwer C, Heine R, Diamant M. 2007. Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study. Atherosclerosis 191: 391-396. (Pubitemid 46400701)
35. Smith GD, Timpson N, Lawlor DA. 2006. C-Reactive Protein and cardiovascular disease risk: still an unknown quantity. Ann Intern Med 145: 70-72. (Pubitemid 46780607)
36. Sun J, Chu YF, Wu XZ, Liu RH. 2002. Antioxidant and anti proliferative activities of common fruits. J Agric Food Chem 50: 7449-7454. (Pubitemid 35424917)
37. Singh U, Dasu MR, Yancey PG, Afify A, Devaraj S, Jialal I. 2008. Human C-Reactive Protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats. J Lipid Res 49: 1015-1023.
38. Utesch D, Feige K, Dasenbrock J, Broschard TH, Harwood M, Danielewska-Nikiel B, Lines TC. 2008. Evaluation of the potential in vivo genotoxicity of quercetin. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 654: 38-44.
39. Vainio H, Weiderpass E. 2006. Fruit and Vegetables in Cancer Prevention. Nutr Cancer 54: 111-142.
40. Valcheva-Kuzmanova S, Kuzmanov K, Mihova V, Krasnaliev I, Borisova P, Belcheva A. 2007. Antihyperlipidemic effect of Aronia melanocarpa fruit juice in rats fed a high-cholesterol diet. Plant Foods Hum Nutr 62: 19-24. (Pubitemid 46327408)
41. Wang Q, Zeng T, Yu L, Xie K. 2007. Preventive effect of garlic oil on fatty liver in experimental rats. Dulixue Zazhi 21: 450-453.
42. Wilson PWF, Nam BH, Pencina M, D'Agostino RB, Benjamin EJ, O'Donnell CJ, Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, Lowe GDO, Pepys MB, Gudnason V. 2005. C-Reactive protein and risk of cardiovascular disease in men and women from the Framingham heart study. Arch Intern Med 165: 2473-2478.