Evaluation of the cytotoxicity, genotoxicity and mutagenicity of diphenyl ditelluride in several biological models

Mutagenesis

Volumn 25, Issue 3, 2010, Pages 257-269

  Degrandi, Tiago Hoerbe ^a   De Oliveira, Iuri Marques ^a   D'Almeida, Gabriel Silveira ^a   Garcia, Cícero Rafael Leão ^a   Villela, Izabel Vianna ^a   Guecheva, Temenouga Nikolova ^a   Rosa, Renato Moreira ^b   Henriques, João Antonio Pêgas ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BIOLOGICAL MARKER; CHEMICAL COMPOUND; DIPHENYL DITELLURIDE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDONUCLEASE; ENDONUCLEASE III; GLUTATHIONE; GLUTATHIONE DISULFIDE; LACTATE DEHYDROGENASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; CELL STRAIN V 79; CHINESE HAMSTER; COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; FRAMESHIFT MUTATION; GENETIC RECOMBINATION; GENOTOXICITY; MICRONUCLEUS; MUTAGENICITY; NONHUMAN; OXIDATIVE STRESS; POINT MUTATION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SALMONELLA TYPHIMURIUM; SINGLE STRANDED DNA BREAK; YEAST;

ANIMALS; BENZENE DERIVATIVES; BIOLOGICAL MARKERS; CELL DEATH; CELL LINE; CELL PROLIFERATION; CRICETINAE; CRICETULUS; DNA DAMAGE; L-LACTATE DEHYDROGENASE; MICROBIAL VIABILITY; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICROSOMES; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; MUTAGENS; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; POINT MUTATION; SACCHAROMYCES CEREVISIAE; SALMONELLA; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

CRICETULUS GRISEUS; SACCHAROMYCES CEREVISIAE; SALMONELLA TYPHIMURIUM;

EID: 77951949601     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq002     Document Type: Article

References (55)

1. Chasteen, T. G., Fuentes, D. E., Tantaleán, J. C. and Vásquez, C. C. (2009) Tellurite: history, oxidative stress, and molecular mechanisms of resistance. FEMS Microbiol. Rev., 1-13.
2. Bienert, G. P., Schüssler, M. D. and Jahn, T. P. (2008) Met al.loids: essential, beneficial or toxic? Major intrinsic proteins sort it out. Trends Biochem. Sci., 33, 20-26.
3. Goodrum, J. F. (1998) Role of organotellurium species in tellurium neuropathy. Neurochem. Res., 23, 1313-1319.
4. Toews, A. D., Eckermann, C. E., Roberson, M. D., Lee, S. Y. and Morell, P. (1991) Primary demyelination induced by exposure to tellurium alters mRNA levels for nerve growth factor receptor, SCIP, 2', 3'-cyclic nucleotide 3'-phosphodiesterase, and myelin proteolipid protein in rat sciatic nerve. Brain Res. Mol. Brain Res., 11, 321-325.
5. Stangherlin, E. C., Rocha, J. B. and Nogueira, C. W. (2009) Diphenyl ditelluride impairs short term memory and alters neurochemical parameters in young rats. Pharmacol. Biochem. Behav., 91, 430-435.
6. Nogueira, C. W., Zen, G. and Rocha, J. B. (2004) Organoselenium and organotellurium compounds: toxicology and pharmacology. Chem. Rev., 104, 6255-6285.
7. Friedman, M., Bayer, I., Letko, I., Duvdevani, R., Zavaro-Levy, O., Ron, B., Albeck, M. and Sredni, B. (2009) Topical treatment for human papillomavirus associated genital warts in humans with the novel tellurium immunomodulator AS101: assessment of its safety and efficacy. Br. J. Dermatol., 160, 403-408.
8. Sailer, B. L., Liles, N., Dickerson, S. and Chasteen, T. G. (2003) Cytometric determination of novel organotellurium compound toxicity in a promyelocytic (HL-60) cell line. Arch. Toxicol., 77, 30-36.
9. Nogueira, C. W., Rotta, L. N., Perry, M. L., Souza, D. O. and Rocha, J. B. (2001) Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo. Brain Res., 906, 157-163.
10. Borges, V. C., Rocha, J. B. and Nogueira, C. W. (2005) Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na (+), K (+) - ATPase activity in rats. Toxicology, 215, 191-197.
11. Moretto, M. B., Boff, B., Franco, J., Posser, T., Roessler, T. M., Souza, D. O., Nogueira, C. W., Wofchuk, S. and Rocha, J. B. (2007) Ca (2+) influx in rat brain: effect of diorganylchalcogenides compounds. Toxicol. Sci., 99, 566-571.
12. Roman, S. S., Nava, A., Favero, A. M., Weis, S. N., Zeni, G., Rocha, J. B. and Nogueira, C. W. (2007) Diphenyl ditelluride effect on embryo/fet al. development in mice: interspecies differences. Toxicology, 231, 243-249.
13. Maciel, E. N., Bolzan, R. C., Braga, A. L. and Rocha, J. B. (2000) Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice. J. Biochem. Mol. Toxicol., 14, 310-319.
14. Schiar, V. P., Dos Santos, D. B., Paixão, M. W., Nogueira, C. W., Rocha, J. B. and Zeni, G. (2009) Human erythrocyte hemolysis induced by selenium and tellurium compounds increased by GSH or glucose: a possible involvement of reactive oxygen species. Chem. Biol. Interact., 177, 28-33.
15. Hassan, W., Ibrahim, M., Nogueira, C. W., Braga, A. L., Deobald, A. M., Mohammadzai, I. U. and Rocha, J. B. (2009) Influence of pH on the reactivity of diphenyl ditelluride with thiols and anti-oxidant potential in rat brain. Chem. Biol. Interact., 180, 47-53.
16. Braga, A. L., Silveira, C. C., Reckziegel, A. and Menezes, P. H. (1993) Convenient preparation of alkynyl selenides, sulfides and tellurides from terminal alkynes and phenylchalcogenyl halides in the presence of copper (I) iodide. Tetrahedron Lett., 34, 8041-8042.
17. Mortelmans, K. and Zeiger, E. (2000) The Ames Salmonella/microsome mutagenicity assay. Mutat. Res., 455, 29-60.
18. Maron, D. M. and Ames, B. N. (1983) Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215.
19. Burke, D., Dawson, D. and Stearns, T. (2000) Methods in Yeast Genetics, Cold Spring Harbour Laboratory Course Manual. CSH Laboratory Press, New York, USA.
20. Von Borstel, R. C., Cain, K. T. and Steinberg, C. M. (1971) Inheritance of spontaneous mutability in yeast. Genetics, 69, 17-27.
21. Bradford, M. A. (1976) Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
22. Salgo, M. G. and Pryor, W. A. (1996) Trolox inhibits peroxynitritemediated oxidative stress and apoptosis in rat thymocytes. Arch. Biochem. Biophys., 15, 482-488.
23. Akerboom, T. and Sies, H. (1981) Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. Meth. Enzymol., 77, 373-382.
24. Decker, T. and Lohmann-Matthes, M. L. (1988) A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J. Immunol. Methods, 115, 61-69.
25. Singh, N. P., McCoy, M. T., Tice, R. R. and Scheider, E. L. (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
26. Tice, R. R., Agurell, E., Anderson, D. et al. (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen., 35, 206-221.
27. Ku, W. W., Bigger, A., Brambilla, G. et al. (2007) Strategy Expert Group, IWGT, Strategy for genotoxicity testing-metabolic considerations. Mutat. Res., 627, 59-77.
28. Bonacker, D., Stoiber, T., Wang, M., Bohm, K. J., Prots, I., Unger, E., Their, R., Bolt, H. M. and Degen, G. H. (2004) Genotoxicity of inorganic mercury salts based on disturbed microtubule function. Arch. Toxicol., 78, 575-583.
29. Fenech, M. (2000) The in vitro micronucleus technique. Mutat. Res., 455, 81-95.
30. Myers, L., Adams, N., Kier, L., Rao, T. K., Shaw, B. and Williams, L. (1991) Microcomputer software for data management and statistical analysis of the Ames/Salmonella test. In Krewski, D. and Franklin, C. A. (eds), Statistics in Toxicology. Gordon and Breach, New York, pp. 265-279.
31. Dizdaroglu, M. (2005) Base-excision repair of oxidative DNA damage by DNA glycosylases. Mutat. Res., 591, 45-59.
32. Gharieb, M. M. and Gadd, G. M. (1998) Evidence for the involvement of vacuolar activity in met al. (loid) tolerance: vacuolar-lacking and-defective mutants of Saccharomyces cerevisiae display higher sensitivity to chromate, tellurite and selenite. Biomet al.s, 2, 101-106.
33. Sailer, B. L., Liles, N., Dickerson, S., Sumners, S. and Chasteen, T. G. (2004) Organotellurium compound toxicity in a promyelocytic cell line compared to non-tellurium-containing organic analog. Toxicol. In Vitro, 18, 475-482.
34. Engman, L., Kandra, T., Gallegos, A., Williams, R. and Powis, G. (2000) Water-soluble organotellurium compounds inhibit thioredoxin reductase and the growth of human cancer cells. Anticancer Drug Des., 15, 323-330.
35. McNaughton, M., Engman, L., Birmingham, A., Powis, G. and Cotgreave, I. A. (2004) Cyclodextrin-derived diorganyl tellurides as glutathione peroxidase mimics and inhibitors of thioredoxin reductase and cancer cell growth. J. Med. Chem., 47, 233-239.
36. Comasseto, J. V., Ling, L. W., Petragnani, N. and Stefani, H. A. (1997) Vinylic selenides and tellurides-preparation, reactivity and synthetic applications. Synthesis, 4, 373-403.
37. Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M. and Mazur, M. (2006) Free radicals, met al.s and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact., 160, 1-40.
38. Borges, V. C., Rocha, J. B., Savegnago, L. and Nogueira, C. W. (2007) Repeated administration of diphenyl ditelluride induces hematological disorders in rats. Food Chem. Toxicol., 45, 1453-1458.
39. Stangherlin, E. C., Ardais, A. P., Rocha, J. B. and Nogueira, C. W. (2009) Exposure to diphenyl ditelluride, via maternal milk, causes oxidative stress in cerebral cortex, hippocampus and striatum of young rats. Arch. Toxicol., 83, 485-491.
40. Zafarullah, M., Li, W. Q., Sylvester, J. and Ahmad, M. (2003) Molecular mechanisms of N-acetylcysteine actions. Cell. Mol. Life Sci., 60, 6-20.
41. Estrela, J. M., Ortega, A. and Obrador, E. (2006) Glutathione in cancer biology and therapy. Crit. Rev. Clin. Lab. Sci, 43, 143-181.
42. Rosa, R. M., Picada, J. D., Saffi, J. and Henriques, J. A. (2007) Cytotoxic, genotoxic, and mutagenic effects of diphenyl diselenide in Chinese hamster lung fibroblasts. Mutat. Res., 628, 87-98.
43. Rosa, R. M., Hoch, N. C., Furtado, G. V., Saffi, J. and Henriques, J. A.
44. -(2007) DNA damage in tissues and organs of mice treated with diphenyl diselenide. Mutat. Res., 633, 35-45.
45. Rosa, R. M., Sulzbacher, K., Picada, J. N., Roesler, R., Saffi, J., Brendel, M. and Henriques, J. A. (2004) Genotoxicity of diphenyl diselenide in bacteria and yeast. Mutat. Res., 563, 107-115.
46. Nogueira, C. W., Borges, V. C., Zeni, G. and Rocha, J. B. (2003) Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro. Toxicology, 191, 169-178.
47. Moretto, M. B., Thomazi, A. P., Godinho, G., Roessler, T. M., Nogueira, C. W., Souza, D. O., Wofchuk, S. and Rocha, J. B. (2007) Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH. Toxicol. In Vitro, 21, 639-645.
48. Boiteux, S. and Guillet, M. (2004) Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair, 3, 1-12.
49. Prakash, S. and Prakash, L. (2000) Nucleotide excision repair in yeast. Mutat. Res., 451, 13-24.
50. Gan, G. N., Wittschieben, J. P., Wittschieben, B. O. and Wood, R. D. (2008) DNA polymerase zeta in higher eukaryotes. Cell Res., 18, 174-183.
51. Yang, Z., Waldmann, A. S. and Wyatt, M. D. (2008) DNA damage and homologous recombination signaling induced by thymidylate deprivation. Biochem. Pharmacol., 76, 987-996.
52. Pastwa, E. and Blasiak, J. (2003) Non-homologous DNA end joining. Acta Biochim. Polonica, 50, 891-908.
53. David, S. S., O'Shea, V. L. and Kundu, S. (2007) Base-excision repair of oxidative DNA damage. Nature, 447, 941-950.
54. Tiano, L., Fedeli, D., Santroni, A. M., Villarini, M., Engman, L. and Falcioni, G. (2000) Effect of three diaryl tellurides, and an organoselenium compound in trout erythrocytes exposed to oxidative stress in vitro. Mutat. Res., 464, 269-277.
55. Migliore, L., Cocchi, L., Nesti, C. and Sabbioni, E. (1999) Micronuclei assay and FISH analysis in human lymphocytes treated with six met al. salts. Environ. Mol. Mutagen., 34, 279-284.