3-Hydroxyflavone inhibits endogenous Aurora B and induces growth inhibition of cancer cell line

Molecular Biology Reports

Volumn 37, Issue 3, 2010, Pages 1577-1583

  Lang, Qingyu ^a   Zhang, Haoxing ^a   Li, Jie ^a   Xie, Fang ^a   Zhang, Yifeng ^a   Wan, Bo ^a   Yu, Long ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Aurora B; Growth inhibition; HTS; Small molecule inhibitor; SPR

Indexed keywords

3 HYDROXYFLAVONE; AURORA B KINASE; CHOLECYSTOKININ OCTAPEPTIDE; HISTONE H3; 3-HYDROXYFLAVONE; ANTINEOPLASTIC AGENT; AURORA KINASE; FLAVONOID; HISTONE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HELA CELL; HIGH THROUGHPUT SCREENING; IC 50; IMAGE ANALYSIS; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HUMAN; METABOLISM; PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL PROLIFERATION; FLAVONOIDS; HELA CELLS; HISTONES; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SURFACE PLASMON RESONANCE; TUMOR STEM CELL ASSAY;

EID: 77951923197     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9562-y     Document Type: Article

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