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Volumn 196, Issue 1-2, 2004, Pages 117-125

Effects of chlorophyllin on transport of dibenzo(a,l)pyrene, 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine, and aflatoxin B1 across Caco-2 cell monolayers

Author keywords

2 Amino 1 methyl 6 phenylimidazo 4,5 b pyridine (PhIP); Aflatoxin B1 (AFB1); Caco 2 cells; Chlorophyllin (CHL); Dibenzo(a,l)pyrene (DBP); Polycyclic aromatic hydrocarbon (PAH)

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO [4,5 B]PYRIDINE; AFLATOXIN B1; CHLOROPHYLL; DIBENZO[A,L]PYRENE; PYRENE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 1242293748     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2003.11.008     Document Type: Article
Times cited : (31)

References (35)
  • 1
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P., Karlsson J. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem. Biophys. Res. Commun. 175:1991;880-885.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 2
    • 0035286778 scopus 로고    scopus 로고
    • Caco-2 monolayers in experimental and theoretical predictions of drug transport
    • Artursson P., Palm K., Luthman K. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv. Drug Deliv. 46:2001;27-43.
    • (2001) Adv. Drug Deliv. , vol.46 , pp. 27-43
    • Artursson, P.1    Palm, K.2    Luthman, K.3
  • 3
  • 4
    • 0030588644 scopus 로고    scopus 로고
    • The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development
    • Bailey C.A., Bryla P., Malick A.W. The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development. Adv. Drug Deliv. Rev. 22:1996;85-103.
    • (1996) Adv. Drug Deliv. Rev. , vol.22 , pp. 85-103
    • Bailey, C.A.1    Bryla, P.2    Malick, A.W.3
  • 5
    • 0027064361 scopus 로고
    • Antioxidants enzymes in he differentiated Caco-2 cell line
    • Baker S.S., Baker R.D. Jr. Antioxidants enzymes in he differentiated Caco-2 cell line. In Vitro Cell Dev. Biol. 28A:1992;643-647.
    • (1992) In Vitro Cell Dev. Biol. , vol.28 , pp. 643-647
    • Baker, S.S.1    Baker, R.D.Jr.2
  • 7
    • 0033566210 scopus 로고    scopus 로고
    • Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: An evaluation of reduced bioavailability vs. target organ protective mechanisms
    • Breinholt V., Arbogast D., Loveland P., Pereira C., Dashwood R., Hendricks J., Bailey G. Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: An evaluation of reduced bioavailability vs. target organ protective mechanisms. Toxicol. Appl. Pharmacol. 158:1999;141-151.
    • (1999) Toxicol. Appl. Pharmacol. , vol.158 , pp. 141-151
    • Breinholt, V.1    Arbogast, D.2    Loveland, P.3    Pereira, C.4    Dashwood, R.5    Hendricks, J.6    Bailey, G.7
  • 8
    • 0029063179 scopus 로고
    • Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: Complex formation with the carcinogen
    • Breinholt V., Schimerlik M., Dashwood R., Bailey G. Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: complex formation with the carcinogen. Chem. Res. Toxicol. 8:1995;506-514.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 506-514
    • Breinholt, V.1    Schimerlik, M.2    Dashwood, R.3    Bailey, G.4
  • 10
    • 0029964530 scopus 로고    scopus 로고
    • Study of the forces stabilizing complexes between chlorophylls and heterocyclic amine mutagens
    • Dashwood R., Yamane S., Larsen R. Study of the forces stabilizing complexes between chlorophylls and heterocyclic amine mutagens. Environ. Mol. Mutagen. 27:1996;211-218.
    • (1996) Environ. Mol. Mutagen. , vol.27 , pp. 211-218
    • Dashwood, R.1    Yamane, S.2    Larsen, R.3
  • 11
    • 0030898639 scopus 로고    scopus 로고
    • Chlorophylls as anticarcinogens (Review)
    • Dashwood R. Chlorophylls as anticarcinogens (Review). Int. J. Oncol. 10:1997;721-727.
    • (1997) Int. J. Oncol. , vol.10 , pp. 721-727
    • Dashwood, R.1
  • 12
    • 0032549474 scopus 로고    scopus 로고
    • Chemopreventive properties of chlorophylls towards aflatoxin B1: A review of the antimutagenicity and anticarcinogenicity data in rainbow trout
    • Dashwood R., Negishi T., Hayatsu H., Breinholt V., Hendricks J., Bailey G. Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout. Mutat. Res. 399:1998;245-253.
    • (1998) Mutat. Res. , vol.399 , pp. 245-253
    • Dashwood, R.1    Negishi, T.2    Hayatsu, H.3    Breinholt, V.4    Hendricks, J.5    Bailey, G.6
  • 13
    • 0030787532 scopus 로고    scopus 로고
    • A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: Advantages and limitations of the Caco-2 model
    • Delie F., Rubas W. A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model. Crit. Rev. Ther. Drug Carrier Syst. 14:1997;221-286.
    • (1997) Crit. Rev. Ther. Drug Carrier Syst. , vol.14 , pp. 221-286
    • Delie, F.1    Rubas, W.2
  • 14
    • 0033805542 scopus 로고    scopus 로고
    • Identification and characterization of chlorine(4) ethyl ester in sera of individuals participating in the chlorophyllin chemoprevention trial
    • Egner P.A., Stansbury K.H., Snyder E.P., Rogers M.E., Hintz P.A., Kensler T.W. Identification and characterization of chlorine(4) ethyl ester in sera of individuals participating in the chlorophyllin chemoprevention trial. Chem. Res. Toxicol. 13:2000;900-906.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 900-906
    • Egner, P.A.1    Stansbury, K.H.2    Snyder, E.P.3    Rogers, M.E.4    Hintz, P.A.5    Kensler, T.W.6
  • 16
    • 0034861702 scopus 로고    scopus 로고
    • Assessment of degradation and intestinal cell uptake of carotenoids and chlorophyll derivatives from spinach puree using an in vitro digestin and Caco-2 human cell model
    • Ferruzzi M.G., Failla M.L., Schwartz S.J. Assessment of degradation and intestinal cell uptake of carotenoids and chlorophyll derivatives from spinach puree using an in vitro digestin and Caco-2 human cell model. J. Agric. Food Chem. 49:2001;2082-2089.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 2082-2089
    • Ferruzzi, M.G.1    Failla, M.L.2    Schwartz, S.J.3
  • 17
    • 0037181331 scopus 로고    scopus 로고
    • Sodium copper chlorophyllin: In vitro digestive stability and accumulation by Caco-2 human intestinal cells
    • Ferruzzi M.G., Failla M.L., Schwartz S.J. Sodium copper chlorophyllin: in vitro digestive stability and accumulation by Caco-2 human intestinal cells. J. Agric. Food Chem. 50:2002;2173-2179.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 2173-2179
    • Ferruzzi, M.G.1    Failla, M.L.2    Schwartz, S.J.3
  • 18
    • 0034467658 scopus 로고    scopus 로고
    • Diet and Cancer. Perspectives of Prevention
    • Greenwald P. Diet and Cancer. Perspectives of Prevention. Adv. Exp. Med. Biol. 472:1999;1-19.
    • (1999) Adv. Exp. Med. Biol. , vol.472 , pp. 1-19
    • Greenwald, P.1
  • 19
    • 0031780682 scopus 로고    scopus 로고
    • Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: Comparison with the partental Caco-2 cell line
    • Grés M.-C., Julian B., Bourrié M., Meunier V., Roques C., Berger M., Boulenc X., Berger Y., Fabre G. Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: comparison with the partental Caco-2 cell line. Pharm. Res. 15(5):1998;726-733.
    • (1998) Pharm. Res. , vol.15 , Issue.5 , pp. 726-733
    • Grés, M.-C.1    Julian, B.2    Bourrié, M.3    Meunier, V.4    Roques, C.5    Berger, M.6    Boulenc, X.7    Berger, Y.8    Fabre, G.9
  • 20
    • 0025283870 scopus 로고
    • Antimutagens and anticarcinogens: A survey of putative interceptor molecules
    • Hartman P.E., Shankel D.M. Antimutagens and anticarcinogens: a survey of putative interceptor molecules. Environ. Mol. Mutagen. 15:1990;145-182.
    • (1990) Environ. Mol. Mutagen. , vol.15 , pp. 145-182
    • Hartman, P.E.1    Shankel, D.M.2
  • 21
    • 0028069481 scopus 로고
    • Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2
    • Hauri H.P., Sander B., Naim H. Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2. Eur. J. Biochem. 219:1994;539-546.
    • (1994) Eur. J. Biochem. , vol.219 , pp. 539-546
    • Hauri, H.P.1    Sander, B.2    Naim, H.3
  • 22
    • 0033973754 scopus 로고    scopus 로고
    • Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: Permeabilities via diffusion, inside- and outside-directed carrier-mediated transport
    • Hilgendorf C., Spahn-Langguth H., Regårdh C.G., Lipka E., Amidon G.L., Langguth P. Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport. J. Pharm. Sci. 89:2000;63-75.
    • (2000) J. Pharm. Sci. , vol.89 , pp. 63-75
    • Hilgendorf, C.1    Spahn-Langguth, H.2    Regårdh, C.G.3    Lipka, E.4    Amidon, G.L.5    Langguth, P.6
  • 23
    • 0026630977 scopus 로고
    • A survey of membrane peptidases in two human colonic cell lines, Caco-2 and HT-29
    • Howell S., Kenny A.J., Turner A.J. A survey of membrane peptidases in two human colonic cell lines, Caco-2 and HT-29. Biochem. J. 284:1992;595-601.
    • (1992) Biochem. J. , vol.284 , pp. 595-601
    • Howell, S.1    Kenny, A.J.2    Turner, A.J.3
  • 25
    • 0002472283 scopus 로고
    • Chlorophyll derivatives - Their chemistry, commercial preparation and uses
    • Kephart J.C. Chlorophyll derivatives - their chemistry, commercial preparation and uses. Econ. Bot. 9:1955;3-38.
    • (1955) Econ. Bot. , vol.9 , pp. 3-38
    • Kephart, J.C.1
  • 26
    • 0028787081 scopus 로고
    • The transport of acidic amino acids and their analogues across monolayers of human intestinal absorptive (Caco-2) cells in vitro
    • Nicklin P.L., Irwin W.J., Hassan I.F., Mackay M., Dixon H.B. The transport of acidic amino acids and their analogues across monolayers of human intestinal absorptive (Caco-2) cells in vitro. Biochem. Biophys. Acta. 1269:1995;176-186.
    • (1995) Biochem. Biophys. Acta , vol.1269 , pp. 176-186
    • Nicklin, P.L.1    Irwin, W.J.2    Hassan, I.F.3    MacKay, M.4    Dixon, H.B.5
  • 27
  • 28
    • 0032828744 scopus 로고    scopus 로고
    • Inhibition of dibenzo[a, l]pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout
    • Reddy A.P., Harttig U., Barth M.C., Baird W.M., Schimerlik M., Hendricks J.D., Bailey G.S. Inhibition of dibenzo[a, l]pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout. Carcinogenesis. 20:1999;1919-1926.
    • (1999) Carcinogenesis , vol.20 , pp. 1919-1926
    • Reddy, A.P.1    Harttig, U.2    Barth, M.C.3    Baird, W.M.4    Schimerlik, M.5    Hendricks, J.D.6    Bailey, G.S.7
  • 29
    • 0036545433 scopus 로고    scopus 로고
    • Preventive effects of chlorophyllin fixed on chitosan towards DNA adduct formation of 3-amino-1-methyl-5H-pyrido [4,3-b]indole in CDF1 mice
    • Sugiyama C., Nakandakari N., Hayatsu H., Arimoto-Kobayashi S. Preventive effects of chlorophyllin fixed on chitosan towards DNA adduct formation of 3-amino-1-methyl-5H-pyrido [4,3-b]indole in CDF1 mice. Biol. Pharm. Bull. 25:2002;520-522.
    • (2002) Biol. Pharm. Bull. , vol.25 , pp. 520-522
    • Sugiyama, C.1    Nakandakari, N.2    Hayatsu, H.3    Arimoto-Kobayashi, S.4
  • 30
    • 0028050207 scopus 로고
    • Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo[a]pyrene: Studies of enzyme inhibition, molecular complex formation and degradation of the ultimate carcinogen
    • Tachino N., Guo D., Dashwood W.M., Yamane S., Larsen R., Dashwood R. Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo[a]pyrene: studies of enzyme inhibition, molecular complex formation and degradation of the ultimate carcinogen. Mutat. Res. 308:1994;191-203.
    • (1994) Mutat. Res. , vol.308 , pp. 191-203
    • Tachino, N.1    Guo, D.2    Dashwood, W.M.3    Yamane, S.4    Larsen, R.5    Dashwood, R.6
  • 32
    • 0030990079 scopus 로고    scopus 로고
    • In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man -fact or myth
    • Yee S. In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man -fact or myth. Pharm. Res. 14:1997;763-766.
    • (1997) Pharm. Res. , vol.14 , pp. 763-766
    • Yee, S.1
  • 33
    • 0032723724 scopus 로고    scopus 로고
    • Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4, 5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: Role of efflux pumps
    • Walle U.K., Walle T. Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: role of efflux pumps. Carcinogenesis. 20:1999;2153-2157.
    • (1999) Carcinogenesis , vol.20 , pp. 2153-2157
    • Walle, U.K.1    Walle, T.2
  • 34
    • 0018921340 scopus 로고
    • Use of chlorophyllin in the care of geriatric patients
    • Young R.W., Beregi J.S. Jr. Use of chlorophyllin in the care of geriatric patients. J. Am. Geriatr. Soc. 28:1980;46-47.
    • (1980) J. Am. Geriatr. Soc. , vol.28 , pp. 46-47
    • Young, R.W.1    Beregi, J.S.Jr.2
  • 35
    • 0029064349 scopus 로고
    • Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes
    • Yun C.H., Jeong H.G., Jhoun J.W., Guengerich F.P. Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. Carcinogenesis. 16:1995;1437-1440.
    • (1995) Carcinogenesis , vol.16 , pp. 1437-1440
    • Yun, C.H.1    Jeong, H.G.2    Jhoun, J.W.3    Guengerich, F.P.4


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