Effect of chlorophyllin against oxidative stress in splenic lymphocytes in vitro and in vivo

Biochimica et Biophysica Acta - General Subjects

Volumn 1672, Issue 2, 2004, Pages 100-111

  Kumar, S Santosh ^a   Shankar, Bhavani ^a   Sainis, Krishna B ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

2,2 azobis(2 propionimidinedihydrochloride); AAPH; Antioxidant; Apoptosis; CHL; Chlorophyllin; DCF; Dichlorodihydrofluorescein diacetate; H2DCF DA; Lipid peroxidation; Lymphocyte; Radioprotection; Reactive oxygen species; ROS

Indexed keywords

2,2' AZOBIS(2 PROPIONIMIDINE); ACETIC ACID DERIVATIVE; CATALASE; CHLOROPHYLL; CONCANAVALIN A; DICHLORODIHYDROFLUORESCEIN DIACETATE; GLUTATHIONE PEROXIDASE; PROPIONAMIDE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LIPID PEROXIDATION; LYMPHOCYTE ACTIVATION; MALE; MITOGENESIS; MITOSIS INHIBITION; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION DOSE; RADIATION PROTECTION; SPLEEN LYMPHOCYTE;

ANIMALS; APOPTOSIS; CHLOROPHYLLIDES; LYMPHOCYTES; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; SPLEEN;

EID: 1942510594     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2004.03.002     Document Type: Article

References (54)

1. Castro L., Freeman B.A. Reactive oxygen species in human health and disease. Nutrition. 17:2001;161-165.
2. Boveris A., Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. 134:1973;707-716.
3. Cross R., Jones O.T.G. Enzymic mechanisms of superoxide production. Biochim. Biophys. Acta. 1057:1991;281-298.
4. Picardo M., Passi S. Free radicals. Bos J.D. Skin Immune System (SIS). 1997;207-226 CRC Press, Boca Raton.
5. Halliwell B., Gutteridge J.M.C. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 219:1984;1-14.
6. Suzuki Y.J., Forman H.J., Sevanian A. Oxidants as stimulators of signal transduction. Free Radic. Biol. Med. 22:1997;269-285.
7. Thannickal V.J., Fanburg B.L. Reactive oxygen species in cell signaling. Am. J. Physiol. 279:2000;L1005-L1028.
8. Hensley K., Robinson K.A., Gabbita S.P., Salsman S., Floyd R.A. Reactive oxygen species, cell signaling, and cell injury. Free Radic. Biol. Med. 28:2000;1456-1462.
9. Schreck R., Albermann K., Baeuerle P.A. Nuclear factor kappa B: an oxidative stress response transcription factor of eukaryotic cells. Free Radic. Res. Commun. 17:1992;221-237.
10. Burdon R.H. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic. Biol. Med. 18:1995;775-794.
11. Mills E.M., Takeda K., Yu Z.X., Ferrans V., Katagiri Y., Jiang H., Lavigne M.C., Leto T.L., Guroff G. Nerve growth factor treatment prevents the increase in superoxide produced by epidermal growth factor in PC12 cells. J. Biol. Chem. 273:1998;22165-22168.
12. Wiseman H., Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313:1996;17-29.
13. Berlett B.S., Stadtman E.R. Protein oxidation in aging, disease and oxidative stress. J. Biol. Chem. 272:1997;20313-20316.
14. Hunt C.R., Sim J.E., Sullivan S.J., Featherstone T., Golden W., Kapp-Herr C.V., Hock R.A., Gomez R.A., Parsian A.J., Spitz D.R. Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress. Cancer Res. 58:1998;3986-3992.
15. Rollet-Labelle E., Grange M.J., Elbim C., Marquetty C., Gougerot-pocidalo M.A., Paquier C. Hydroxyl radical as a potential intracellular mediator of polymorphonuclear neutrophil apoptosis. Free Radic. Biol. Med. 24:1998;563-572.
16. Kehrer J.P. Free radicals as mediators of tissue injury and disease. Crit. Rev. Toxicol. 23:1993;21-48.
17. Kannan K., Jain S.K. Oxidative stress and apoptosis. Pathophysiology. 7:2000;153-163.
18. Riley P.A. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol. 65:1994;27-33.
19. Trush M.A., Mimnaugh E.C., Gram T.E. Activation of pharmacologic agents to radical intermediates: implication for the role of free radicals in drug action and toxicity. Biochem. Pharmacol. 31:1982;3335-3346.
20. Heng-Long H., Forsey R.J., Blades T.J., Barratt M.E.J., Parmar P., Powell J.R. Antioxidants may contribute in fight against ageing: an in vitro model. Mech. Ageing Dev. 121:2000;217-230.
21. Dewey W.C., Ling C.C., Meyn R.E. Radiation-induced apoptosis: relevance to radiotherapy Int. J. Radiat. Oncol. Biol. Phys. 21:1990;109-122.
22. Curtin J.F., Donovan M., Cotter T.G. Regulation and measurement of oxidative stress in apoptosis. J. Immunol. Methods. 265:2002;49-72.
23. Chandra J., Samali A., Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29:2000;323-333.
24. Gate L., Paul J., Nguyen Ba G., Tew K.D., Tapiero H. Oxidative stress induced in pathologies: the role of antioxidants. Biomed. Pharmacother. 53:1999;169-180.
25. Thompson C.B. Apoptosis in pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
26. Astley S.B. Dietary antioxidants - past, present and future? Trends Food Sci. Technol. 14:2003;93-98.
27. Greenstock C.L. Radiation and ageing: free radical damage, biological response and antioxidant intervention. Med. Hypotheses. 41:1993;473-482.
28. Egner P.A., Wang J.-B., Zhu Y.-R., Zhang B.-C., Wu Y., Zhang Q.-N., Qian Q.-S., Kuang S.-Y., Gange S.J., Jacobson L.P., Helzlsouer K.J., Bailey G.S., Groopman J.D., Kensler T.W. Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer. Proc. Natl. Acad. Sci. U. S. A. 98:2001;14601-14606.
29. Chernomorsky S., Rancourt R., Virdi K., Segelman A., Poretz R.D. Antimutageneicity, cytotoxicity and composition of chlorophyllin copper complex. Cancer Lett. 120:1997;141-147.
30. Ong T.M., Whong W.Z., Stewart J., Brockman H.E. Chlorophyllin: a potent antimutagen against environmental and dietary complex mixtures. Mutat. Res. 173:1986;111-115.
31. Waters M.D., Stack H.F., Jackson M.A., Brockman H.E., De Flora S. Activity profiles of antimutagens: in vitro and in vivo data. Mutat. Res. 350:1996;109-129.
32. Guo D., Horio D.T., Grove J.S., Dashwood R.H. Inhibition by chlorophyllin of 2-amino-3-methylimidazo-[4,5-f]quinoline induced tumorigenesis in male F344 rat. Cancer Lett. 95:1995;161-165.
33. Hasegawa R., Hirose M., Kato T., Hagiwara A., Boonyaphiphat P., Nagao M., Ito N., Shirai T. Inhibotory effect of chlorophyllin on PhIP-induced mammary carcinogenesis in female F344 rats. Carcinogenesis. 16:1995;2243-2246.
34. Park K.K., Surh Y.J. Chemopreventive activity of chlorophyllin against mouse skin carcinogenesis by benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol- 9,10-epoxide. Cancer Lett. 102:1996;143-149.
35. Te C., Gentile J.M., Baguley B.C., Pearson A.E., Gregory T., Ferguson L.R. In vivo effects of chlorophyllin on the antitumor agent cyclophosphamide. Int. J. Cancer. 70:1997;84-89.
36. Young R.W., Bergei J.S. Use of chlorophyllin in the care of geriatric patients. J. Am. Geriat. Soc. 24:1980;46-47.
37. Arimoto S., Fukuoka S., Itome C., Nakano H., Rai H., Hayatsu H. Binding of polycyclic planar mutagens to chlorophyllin resulting in inhibition of the mutagenic activity. Mutat. Res. 287:1993;293-305.
38. Yun C.H., Jeong H.G., Jhuon J.W., Gengerich F.P. Nonspecific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. Carcinogenesis. 16:1995;1437-1440.
39. Abraham S.K., Sarma L., Kesavan P.C. Role of chlorophyllin as an in vivo anticlastogen: protection against gamma radiation and chemical clastogens. Mutat. Res. 322:1994;209-212.
40. Morales-Ramirez P., Garcia-Rodriguez M.C. In vivo effect of chlorophyllin on γ-ray induced sister chromatid exchanges in murine bone marrow cells. Mutat. Res. 320:1994;329-334.
41. Morales-Ramirez P., Mendiola-Cruz M.T. In vivo radioprotective effect of chlorophyllin on sister chromatid exchange induction in murine spermatogonial cells. Mutat. Res. 344:1995;73-78.
42. Morales-Ramirez P., Vallarino-Kelley T., Rodriguez-Reyes R. Effect of chlorophyllin on gamma ray induced micronuclei in polychromatic erythrocytes of murine peripheral blood determined by the ABC strategy. Mutat. Res. 367:1996;51-56.
43. Santosh Kumar S., Chaubey R.C., Devasagayam T.P.A., Priyadarsini K.I., Chauhan P.S. Inhibition of radiation induced DNA damage in plasmid pBR322 by chlorophyllin and possible mechanism(s) action. Mutat. Res. 425:1999;71-79.
44. Santosh Kumar S., Devasagayam T.P.A., Bhushan B., Verma N.C. Scavenging of reactive oxygen species by chlorophyllin: an ESR study. Free Radic. Res. 35:2001;563-574.
45. 2-induced apoptosis of HL-60 Human Leukemia cells. J. Biol. Chem. 275:2000;22461-22469.
46. Lyons A.B., Doherty K.V. Flow cytometric analysis of cell division by dye dilution. Current Protocols in Cytometry. 1998;9.11.1-9.11.9 Wiley.
47. Bhavani S., Santosh Kumar S., Sainis K.B. Generation of reactive oxygen species and radiation response in lymphocytes and tumor cells. Radiat. Res. 160:2003;150-159.
48. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
49. Bergmeyer H.V. Meth. Enz. Anal. vol. 1:1974;438 Academic Press, NewYork.
50. Mosca L., Marcellini S., Perluigi M., Mastroiacovo P., Moretti S., Famularo G., Peluso I., Santini G., Simone C.D. Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula. Biochem. Pharmacol. 63:2002;1305-1314.
51. Weiss J.F., Simic M.G. Perspectives in radioprotection. Pharmacol. Ther. 39:1988;1-414.
52. Bump E.A., Malaker K. Radioprotectors: Chemical, Biological and Clinical Perspective. 1998;1-431 CRC Press, Boca Raton, FL.
53. Weiss J.F., Kumar K.S., Walden T.L., Neta R., Landauer M.R., Clark E.P. Advances in radioprotection through the use of combined agent regimens. Int. J. Radiat. Biol. 57:1990;709-722.
54. Sato M., Imal K., Kimura R., Murata T. Effect of sodium copper chlorophyllin on lipid peroxidation: VI. Effects of its administration on mitochondria and microsomal lipid peroxidation in rat liver. Chem. Pharm. Bull. 32:1984;715-722.