Pharmacophore modeling, virtual screening and molecular docking studies for identification of new inverse agonists of human histamine H1 receptor

Bulletin of the Korean Chemical Society

Volumn 31, Issue 1, 2010, Pages 52-58

  Thangapandian, Sundarapandian ^a   Krishnamoorthy, Navaneethakrishnan ^a   John, Shalini ^a   Sakkiah, Sugunadevi ^a   Lazar, Prettina ^a   Lee, Yuno ^a   Lee, Keun Woo ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Histamine H1 receptor; Inverse agonists; Ligandfit; Lipinski's rule; Pharmacophore

Indexed keywords

ACTIVE SITE; BEST MODEL; CORRELATION COEFFICIENT; CORRELATION VALUE; G PROTEIN COUPLED RECEPTORS; HOMOLOGY MODELS; HYDROGEN BOND ACCEPTORS; MOLECULAR DOCKING; NOVEL MOLECULES; PHARMACOPHORE MODELING; PHARMACOPHORE MODELS; PHARMACOPHORES; TEST SETS; TRAINING SETS; VIRTUAL SCREENING;

AMINO ACIDS; CATALYST ACTIVITY; HYDROGEN BONDS; ORGANIC ACIDS; PHARMACODYNAMICS; VIRTUAL REALITY;

THREE DIMENSIONAL;

EID: 77951872679     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2010.31.01.052     Document Type: Article

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