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Volumn 90, Issue 5, 2010, Pages 685-695

Bone marrow mononuclear cells attenuate fibrosis development after severe acute kidney injury

Author keywords

Acute kidney injury; Bone marrow; Fibrosis; Inflammation; Ischemia reperfusion injury; Mesenchymal stem cell

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; HEME OXYGENASE 1; INTERFERON RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; OSTEOGENIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

EID: 77951802604     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.45     Document Type: Article
Times cited : (33)

References (75)
  • 1
    • 41649120196 scopus 로고    scopus 로고
    • Long-term outcomes after acute kidney injury
    • Morgera S, Schneider M, Neumayer HH. Long-term outcomes after acute kidney injury. Crit Care Med 2008;36(4 Suppl):S193-S197.
    • (2008) Crit Care Med , vol.36 , Issue.4 SUPPL.
    • Morgera, S.1    Schneider, M.2    Neumayer, H.H.3
  • 3
    • 4143120048 scopus 로고    scopus 로고
    • Delta analysis of posttransplantation tubulointerstitial damage
    • Nankivell BJ, Borrows RJ, Fung CL, et al. Delta analysis of posttransplantation tubulointerstitial damage. Transplantation 2004;78:434-441.
    • (2004) Transplantation , vol.78 , pp. 434-441
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 5
    • 20844462254 scopus 로고    scopus 로고
    • Persistent renal and extrarenal immune changes after severe ischemic injury
    • Burne-Taney MJ, Yokota N, Rabb H. Persistent renal and extrarenal immune changes after severe ischemic injury. Kidney Int 2005;67:1002-1009.
    • (2005) Kidney Int , vol.67 , pp. 1002-1009
    • Burne-Taney, M.J.1    Yokota, N.2    Rabb, H.3
  • 6
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003;112:1776-1784.
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 7
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, et al. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006;172:973-981.
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3
  • 8
    • 52049087551 scopus 로고    scopus 로고
    • Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis
    • Zeisberg M, Kalluri R. Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis. Front Biosci 2008;13:6991-6998.
    • (2008) Front Biosci , vol.13 , pp. 6991-6998
    • Zeisberg, M.1    Kalluri, R.2
  • 9
    • 34250733867 scopus 로고    scopus 로고
    • The role of tubular epithelial-mesenchymal transition in progressive kidney disease
    • Burns WC, Kantharidis P, Thomas MC. The role of tubular epithelial-mesenchymal transition in progressive kidney disease. Cells Tissues Organs 2007;185:222-231.
    • (2007) Cells Tissues Organs , vol.185 , pp. 222-231
    • Burns, W.C.1    Kantharidis, P.2    Thomas, M.C.3
  • 10
    • 0036783550 scopus 로고    scopus 로고
    • TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells
    • Gore-Hyer E, Shegogue D, Markiewicz M, et al. TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells. Am J Physiol Renal Physiol 2002;283:F707-F716.
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Gore-Hyer, E.1    Shegogue, D.2    Markiewicz, M.3
  • 11
    • 33748486969 scopus 로고    scopus 로고
    • Connective tissue growth factor is a biomarker and mediator of kidney allograft fibrosis
    • Cheng O, Thuillier R, Sampson E, et al. Connective tissue growth factor is a biomarker and mediator of kidney allograft fibrosis. Am J Transplant 2006;6:2292-2306.
    • (2006) Am J Transplant , vol.6 , pp. 2292-2306
    • Cheng, O.1    Thuillier, R.2    Sampson, E.3
  • 13
    • 0036785218 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice
    • Yang J, Dai C, Liu Y. Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice. J Am Soc Nephrol 2002;13:2464-2477.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2464-2477
    • Yang, J.1    Dai, C.2    Liu, Y.3
  • 14
    • 33846189299 scopus 로고    scopus 로고
    • Mycophenolate mofetil is associated with altered expression of chronic renal transplant histology
    • Nankivell BJ, Wavamunno MD, Borrows RJ, et al. Mycophenolate mofetil is associated with altered expression of chronic renal transplant histology. Am J Transplant 2007;7:366-376.
    • (2007) Am J Transplant , vol.7 , pp. 366-376
    • Nankivell, B.J.1    Wavamunno, M.D.2    Borrows, R.J.3
  • 15
    • 33745016299 scopus 로고    scopus 로고
    • Mycophenolate mofetil ameliorates accelerated progressive nephropathy in rat
    • Bloudickova S, Rajnoch J, Lodererova A, et al. Mycophenolate mofetil ameliorates accelerated progressive nephropathy in rat. Kidney Blood Press Res 2006;29:60-66.
    • (2006) Kidney Blood Press Res , vol.29 , pp. 60-66
    • Bloudickova, S.1    Rajnoch, J.2    Lodererova, A.3
  • 17
    • 0242582117 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
    • Zeisberg M, Bottiglio C, Kumar N, et al. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol 2003;285: F1060-F1067.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Zeisberg, M.1    Bottiglio, C.2    Kumar, N.3
  • 18
    • 42549116610 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 (BMP7) in chronic kidney disease
    • Mitu G, Hirschberg R. Bone morphogenetic protein-7 (BMP7) in chronic kidney disease. Front Biosci 2008;13:4726-4739.
    • (2008) Front Biosci , vol.13 , pp. 4726-4739
    • Mitu, G.1    Hirschberg, R.2
  • 19
    • 33645008016 scopus 로고    scopus 로고
    • Renoprotective effects of renin-angiotensin-system inhibitors
    • author reply-2
    • de Zeeuw D, Lewis EJ, Remuzzi G, et al. Renoprotective effects of renin-angiotensin-system inhibitors. Lancet 2006;367:899-900; author reply-2.
    • (2006) Lancet , vol.367 , pp. 899-900
    • De Zeeuw, D.1    Lewis, E.J.2    Remuzzi, G.3
  • 20
    • 0037117570 scopus 로고    scopus 로고
    • Chronic renal diseases: Renoprotective benefits of renin-angiotensin system inhibition
    • Remuzzi G, Ruggenenti P, Perico N. Chronic renal diseases: renoprotective benefits of renin-angiotensin system inhibition. Ann Intern Med 2002;136:604-615.
    • (2002) Ann Intern Med , vol.136 , pp. 604-615
    • Remuzzi, G.1    Ruggenenti, P.2    Perico, N.3
  • 21
    • 52749083291 scopus 로고    scopus 로고
    • Stem cell based therapy for skeletal muscle diseases
    • Bhagavati S. Stem cell based therapy for skeletal muscle diseases. Curr Stem Cell Res Ther 2008;3:219-228.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 219-228
    • Bhagavati, S.1
  • 22
    • 52749092498 scopus 로고    scopus 로고
    • Adult stem cell transplantation in stroke: Its limitations and prospects
    • Roh JK, Jung KH, Chu K. Adult stem cell transplantation in stroke: its limitations and prospects. Curr Stem Cell Res Ther 2008;3:185-196.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 185-196
    • Roh, J.K.1    Jung, K.H.2    Chu, K.3
  • 24
    • 34249662219 scopus 로고    scopus 로고
    • IFN-gamma and TNF-alpha differentially regulate immunomodulation by murine mesenchymal stem cells
    • English K, Barry FP, Field-Corbett CP, et al. IFN-gamma and TNF-alpha differentially regulate immunomodulation by murine mesenchymal stem cells. Immunol Lett 2007;110:91-100.
    • (2007) Immunol Lett , vol.110 , pp. 91-100
    • English, K.1    Barry, F.P.2    Field-Corbett, C.P.3
  • 25
    • 33746889097 scopus 로고    scopus 로고
    • Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
    • Krampera M, Cosmi L, Angeli R, et al. Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells 2006;24:386-398.
    • (2006) Stem Cells , vol.24 , pp. 386-398
    • Krampera, M.1    Cosmi, L.2    Angeli, R.3
  • 26
    • 41649101896 scopus 로고    scopus 로고
    • Renal repair and recovery
    • Liu KD, Brakeman PR. Renal repair and recovery. Crit Care Med 2008;36(4 Suppl):S187-S192.
    • (2008) Crit Care Med , vol.36 , Issue.4 SUPPL.
    • Liu, K.D.1    Brakeman, P.R.2
  • 27
    • 39649113771 scopus 로고    scopus 로고
    • Mesenchymal stem cells in acute kidney injury
    • Humphreys BD, Bonventre JV. Mesenchymal stem cells in acute kidney injury. Annu Rev Med 2008;59:311-325.
    • (2008) Annu Rev Med , vol.59 , pp. 311-325
    • Humphreys, B.D.1    Bonventre, J.V.2
  • 28
    • 20844440562 scopus 로고    scopus 로고
    • Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
    • DOI 10.1152/ajprenal.00007.2005
    • Togel F, Hu Z, Weiss K, et al. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289: F31-F42. (Pubitemid 40863570)
    • (2005) American Journal of Physiology - Renal Physiology , vol.289 , Issue.1
    • Togel, F.1    Hu, Z.2    Weiss, K.3    Isaac, J.4    Lange, C.5    Westenfelder, C.6
  • 29
    • 33847716669 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury
    • Semedo P, Wang PM, Andreucci TH, et al. Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury. Transplant Proc 2007;39:421-423.
    • (2007) Transplant Proc , vol.39 , pp. 421-423
    • Semedo, P.1    Wang, P.M.2    Andreucci, T.H.3
  • 30
    • 42949116571 scopus 로고    scopus 로고
    • Effect of whole bone marrow cell infusion in the progression of experimental chronic renal failure
    • Caldas HC, Fernandes IM, Gerbi F, et al. Effect of whole bone marrow cell infusion in the progression of experimental chronic renal failure. Transplant Proc 2008;40:853-855.
    • (2008) Transplant Proc , vol.40 , pp. 853-855
    • Caldas, H.C.1    Fernandes, I.M.2    Gerbi, F.3
  • 31
    • 44949153476 scopus 로고    scopus 로고
    • Long-term outcomes of acute kidney injury
    • Goldberg R, Dennen P. Long-term outcomes of acute kidney injury. Adv Chronic Kidney Dis 2008;15:297-307.
    • (2008) Adv Chronic Kidney Dis , vol.15 , pp. 297-307
    • Goldberg, R.1    Dennen, P.2
  • 32
    • 52449133909 scopus 로고    scopus 로고
    • Acute kidney injury: New concepts, renal recovery
    • Bell M. Acute kidney injury: new concepts, renal recovery. Nephron Clin Pract 2008;109:c224-c228.
    • (2008) Nephron Clin Pract , vol.109
    • Bell, M.1
  • 34
    • 48149106014 scopus 로고    scopus 로고
    • Acute kidney injury leads to inflammation and functional changes in the brain
    • Liu M, Liang Y, Chigurupati S, et al. Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol 2008;19:1360-1370.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1360-1370
    • Liu, M.1    Liang, Y.2    Chigurupati, S.3
  • 35
    • 51849102110 scopus 로고    scopus 로고
    • Uremic lung: New insights into a forgotten condition
    • Scheel PJ, Liu M, Rabb H. Uremic lung: new insights into a forgotten condition. Kidney Int 2008;74:849-851.
    • (2008) Kidney Int , vol.74 , pp. 849-851
    • Scheel, P.J.1    Liu, M.2    Rabb, H.3
  • 36
    • 65549094658 scopus 로고    scopus 로고
    • Kidney-lung crosstalk in the critically ill patient
    • Ko GJ, Rabb H, Hassoun HT. Kidney-lung crosstalk in the critically ill patient. Blood Purif 2009;28:75-83.
    • (2009) Blood Purif , vol.28 , pp. 75-83
    • Ko, G.J.1    Rabb, H.2    Hassoun, H.T.3
  • 37
    • 65549118392 scopus 로고    scopus 로고
    • Effects of different periods of renal ischemia on liver as a remote organ
    • Kadkhodaee M, Golab F, Zahmatkesh M, et al. Effects of different periods of renal ischemia on liver as a remote organ. World J Gastroenterol 2009;15:1113-1118.
    • (2009) World J Gastroenterol , vol.15 , pp. 1113-1118
    • Kadkhodaee, M.1    Golab, F.2    Zahmatkesh, M.3
  • 38
    • 0029592790 scopus 로고
    • Acute renal injury in the interferon-gamma gene knockout mouse: Effect on cytokine gene expression
    • Goes N, Urmson J, Vincent D, et al. Acute renal injury in the interferon-gamma gene knockout mouse: effect on cytokine gene expression. Transplantation 1995;60:1560-1564.
    • (1995) Transplantation , vol.60 , pp. 1560-1564
    • Goes, N.1    Urmson, J.2    Vincent, D.3
  • 39
    • 40449094520 scopus 로고    scopus 로고
    • The local and systemic inflammatory transcriptome after acute kidney injury
    • Grigoryev DN, Liu M, Hassoun HT, et al. The local and systemic inflammatory transcriptome after acute kidney injury. J Am Soc Nephrol 2008;19:547-558.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 547-558
    • Grigoryev, D.N.1    Liu, M.2    Hassoun, H.T.3
  • 40
    • 33746054494 scopus 로고    scopus 로고
    • Interleukin-5 regulates genes involved in B-cell terminal maturation
    • Horikawa K, Takatsu K. Interleukin-5 regulates genes involved in B-cell terminal maturation. Immunology 2006;118:497-508.
    • (2006) Immunology , vol.118 , pp. 497-508
    • Horikawa, K.1    Takatsu, K.2
  • 42
    • 33745231146 scopus 로고    scopus 로고
    • Immune modulation by mesenchymal stem cells
    • Rasmusson I. Immune modulation by mesenchymal stem cells. Exp Cell Res 2006;312:2169-2179.
    • (2006) Exp Cell Res , vol.312 , pp. 2169-2179
    • Rasmusson, I.1
  • 43
    • 34447576602 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells and immune tolerance
    • Noel D, Djouad F, Bouffi C, et al. Multipotent mesenchymal stromal cells and immune tolerance. Leuk Lymphoma 2007;48:1283-1289.
    • (2007) Leuk Lymphoma , vol.48 , pp. 1283-1289
    • Noel, D.1    Djouad, F.2    Bouffi, C.3
  • 44
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B, et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 45
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 46
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002;99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 47
    • 52949115668 scopus 로고    scopus 로고
    • Immunosuppressive properties of mesenchymal stem cells derived from bone marrow of patients with chronic myeloid leukemia
    • Zhao ZG, Li WM, Chen ZC, et al. Immunosuppressive properties of mesenchymal stem cells derived from bone marrow of patients with chronic myeloid leukemia. Immunol Invest 2008;37:726-739.
    • (2008) Immunol Invest , vol.37 , pp. 726-739
    • Zhao, Z.G.1    Li, W.M.2    Chen, Z.C.3
  • 48
    • 33846006154 scopus 로고    scopus 로고
    • Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
    • Sato K, Ozaki K, Oh I, et al. Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007;109:228-234.
    • (2007) Blood , vol.109 , pp. 228-234
    • Sato, K.1    Ozaki, K.2    Oh, I.3
  • 49
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, et al. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004;103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3
  • 50
    • 37249067491 scopus 로고    scopus 로고
    • Adult bone marrow-derived stem cells for organ regeneration and repair
    • DOI 10.1002/dvdy.21258
    • Togel F, Westenfelder C. Adult bone marrow-derived stem cells for organ regeneration and repair. Dev Dyn 2007;236:3321-3331. (Pubitemid 350276389)
    • (2007) Developmental Dynamics , vol.236 , Issue.12 , pp. 3321-3331
    • Togel, F.1    Westenfelder, C.2
  • 51
    • 49649087513 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition in early transplant tubulointerstitial damage
    • Vitalone MJ, O'Connell PJ, Jimenez-Vera E, et al. Epithelial-to- mesenchymal transition in early transplant tubulointerstitial damage. J Am Soc Nephrol 2008;19:1571-1583.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1571-1583
    • Vitalone, M.J.1    O'Connell, P.J.2    Jimenez-Vera, E.3
  • 52
    • 60749103842 scopus 로고    scopus 로고
    • EMT and proteinuria as progression factors
    • Aug 20
    • Strutz FM. EMT and proteinuria as progression factors. Kidney Int 2008, Aug 20.
    • (2008) Kidney Int
    • Strutz, F.M.1
  • 53
    • 44649088828 scopus 로고    scopus 로고
    • Molecular pathways involved in loss of kidney graft function with tubular atrophy and interstitial fibrosis
    • Maluf DG, Mas VR, Archer KJ, et al. Molecular pathways involved in loss of kidney graft function with tubular atrophy and interstitial fibrosis. Mol Med 2008;14:276-285.
    • (2008) Mol Med , vol.14 , pp. 276-285
    • Maluf, D.G.1    Mas, V.R.2    Archer, K.J.3
  • 54
    • 49649101155 scopus 로고    scopus 로고
    • Early epithelial phenotypic changes predict graft fibrosis
    • Hertig A, Anglicheau D, Verine J, et al. Early epithelial phenotypic changes predict graft fibrosis. J Am Soc Nephrol 2008;19:1584-1591.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1584-1591
    • Hertig, A.1    Anglicheau, D.2    Verine, J.3
  • 55
    • 36148955109 scopus 로고    scopus 로고
    • Mechanisms of progression of chronic kidney disease
    • Fogo AB. Mechanisms of progression of chronic kidney disease. Pediatr Nephrol 2007;22:2011-2022.
    • (2007) Pediatr Nephrol , vol.22 , pp. 2011-2022
    • Fogo, A.B.1
  • 56
    • 57349194661 scopus 로고    scopus 로고
    • Inflammatory cytokines augments TGF-beta1-induced epithelial-mesenchymal transition in A549 cells by up-regulating TbetaR-I
    • Liu X. Inflammatory cytokines augments TGF-beta1-induced epithelial-mesenchymal transition in A549 cells by up-regulating TbetaR-I. Cell Motil Cytoskeleton 2008;65:935-944.
    • (2008) Cell Motil Cytoskeleton , vol.65 , pp. 935-944
    • Liu, X.1
  • 57
    • 36849021771 scopus 로고    scopus 로고
    • Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
    • Higgins DF, Kimura K, Bernhardt WM, et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 2007;117:3810-3820.
    • (2007) J Clin Invest , vol.117 , pp. 3810-3820
    • Higgins, D.F.1    Kimura, K.2    Bernhardt, W.M.3
  • 58
    • 36248929390 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition and chronic allograft tubulointerstitial fibrosis
    • Bedi S, Vidyasagar A, Djamali A. Epithelial-to-mesenchymal transition and chronic allograft tubulointerstitial fibrosis. Transplant Rev (Orlando) 2008;22:1-5.
    • (2008) Transplant Rev (Orlando) , vol.22 , pp. 1-5
    • Bedi, S.1    Vidyasagar, A.2    Djamali, A.3
  • 59
    • 34250665408 scopus 로고    scopus 로고
    • Molecular evidence of injury and inflammation in normal and fibrotic renal allografts one year posttransplant
    • Park W, Griffin M, Grande JP, et al. Molecular evidence of injury and inflammation in normal and fibrotic renal allografts one year posttransplant. Transplantation 2007;83:1466-1476.
    • (2007) Transplantation , vol.83 , pp. 1466-1476
    • Park, W.1    Griffin, M.2    Grande, J.P.3
  • 60
    • 43249107158 scopus 로고    scopus 로고
    • Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells
    • Chuang MJ, Sun KH, Tang SJ, et al. Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells. Cancer Sci 2008;99:905-913.
    • (2008) Cancer Sci , vol.99 , pp. 905-913
    • Chuang, M.J.1    Sun, K.H.2    Tang, S.J.3
  • 61
    • 0035061819 scopus 로고    scopus 로고
    • Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro
    • Fan JM, Huang XR, Ng YY, et al. Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro. Am J Kidney Dis 2001;37:820-831.
    • (2001) Am J Kidney Dis , vol.37 , pp. 820-831
    • Fan, J.M.1    Huang, X.R.2    Ng, Y.Y.3
  • 62
    • 34147176657 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: Effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone
    • Copeland JW, Beaumont BW, Merrilees MJ, et al. Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone. Transplantation 2007;83:809-814.
    • (2007) Transplantation , vol.83 , pp. 809-814
    • Copeland, J.W.1    Beaumont, B.W.2    Merrilees, M.J.3
  • 63
    • 36749101547 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 delays podocyte injury due to high glucose
    • De Petris L, Hruska KA, Chiechio S, et al. Bone morphogenetic protein-7 delays podocyte injury due to high glucose. Nephrol Dial Transplant 2007;22:3442-3450.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 3442-3450
    • De Petris, L.1    Hruska, K.A.2    Chiechio, S.3
  • 64
    • 34250696880 scopus 로고    scopus 로고
    • Reversal of renal disease: Is it enough to inhibit the action of angiotensin II?
    • Dussaule JC, Chatziantoniou C. Reversal of renal disease: is it enough to inhibit the action of angiotensin II? Cell Death Differ 2007;14: 1343-1349.
    • (2007) Cell Death Differ , vol.14 , pp. 1343-1349
    • Dussaule, J.C.1    Chatziantoniou, C.2
  • 65
    • 33748062324 scopus 로고    scopus 로고
    • Renal bone morphogenetic protein-7 protects against diabetic nephropathy
    • Wang S, de Caestecker M, Kopp J, et al. Renal bone morphogenetic protein-7 protects against diabetic nephropathy. J Am Soc Nephrol 2006;17:2504-2512.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2504-2512
    • Wang, S.1    De Caestecker, M.2    Kopp, J.3
  • 66
    • 33644864525 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 and the kidney: Current concepts and open questions
    • Zeisberg M. Bone morphogenic protein-7 and the kidney: current concepts and open questions. Nephrol Dial Transplant 2006;21:568-573.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 568-573
    • Zeisberg, M.1
  • 67
    • 27844595882 scopus 로고    scopus 로고
    • BMP7 signaling in renal development and disease
    • Patel SR, Dressler GR. BMP7 signaling in renal development and disease. Trends Mol Med 2005;11:512-518.
    • (2005) Trends Mol Med , vol.11 , pp. 512-518
    • Patel, S.R.1    Dressler, G.R.2
  • 68
    • 24044443901 scopus 로고    scopus 로고
    • Downregulation of the expression of bone morphogenetic protein 7 in experimental pyelonephritis
    • Biyikli NK, Tugtepe H, Cakalagaoglu F, et al. Downregulation of the expression of bone morphogenetic protein 7 in experimental pyelonephritis. Pediatr Nephrol 2005;20:1230-1236.
    • (2005) Pediatr Nephrol , vol.20 , pp. 1230-1236
    • Biyikli, N.K.1    Tugtepe, H.2    Cakalagaoglu, F.3
  • 69
    • 3242883324 scopus 로고    scopus 로고
    • Osteogenic protein-1: Gene expression and treatment in rat remnant kidney model
    • Dube PH, Almanzar MM, Frazier KS, et al. Osteogenic protein-1: gene expression and treatment in rat remnant kidney model. Toxicol Pathol 2004;32:384-392.
    • (2004) Toxicol Pathol , vol.32 , pp. 384-392
    • Dube, P.H.1    Almanzar, M.M.2    Frazier, K.S.3
  • 70
    • 47749136233 scopus 로고    scopus 로고
    • Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease
    • Zeisberg M, Kalluri R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatr Nephrol 2008;23:1395-1398.
    • (2008) Pediatr Nephrol , vol.23 , pp. 1395-1398
    • Zeisberg, M.1    Kalluri, R.2
  • 71
    • 17644396635 scopus 로고    scopus 로고
    • Setting a trap for tissue fibrosis
    • Neilson EG. Setting a trap for tissue fibrosis. Nat Med 2005;11:373-374.
    • (2005) Nat Med , vol.11 , pp. 373-374
    • Neilson, E.G.1
  • 72
    • 55749110617 scopus 로고    scopus 로고
    • Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis
    • Feitoza CQ, Goncalves GM, Semedo P, et al. Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis. Mol Med 2008;14:724-730.
    • (2008) Mol Med , vol.14 , pp. 724-730
    • Feitoza, C.Q.1    Goncalves, G.M.2    Semedo, P.3
  • 73
    • 13844280253 scopus 로고    scopus 로고
    • Heme oxygenase-1 (HO-1), a protective gene that prevents chronic graft dysfunction
    • Camara NO, Soares MP. Heme oxygenase-1 (HO-1), a protective gene that prevents chronic graft dysfunction. Free Radic Biol Med 2005;38:426-435.
    • (2005) Free Radic Biol Med , vol.38 , pp. 426-435
    • Camara, N.O.1    Soares, M.P.2
  • 74
    • 33646356719 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects rat kidney from ureteral obstruction via an antiapoptotic pathway
    • Kim JH, Yang JI, Jung MH, et al. Heme oxygenase-1 protects rat kidney from ureteral obstruction via an antiapoptotic pathway. J Am Soc Nephrol 2006;17:1373-1381.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1373-1381
    • Kim, J.H.1    Yang, J.I.2    Jung, M.H.3
  • 75
    • 54749083116 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis
    • Kie JH, Kapturczak MH, Traylor A, et al. Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis. J Am Soc Nephrol 2008;19:1681-1691.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1681-1691
    • Kie, J.H.1    Kapturczak, M.H.2    Traylor, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.