Mesenchymal Stem Cells Ameliorate Tissue Damages Triggered by Renal Ischemia and Reperfusion Injury

Transplantation Proceedings

Volumn 39, Issue 2, 2007, Pages 421-423

  Semedo, P ^a   Wang, P M ^a   Andreucci, T H ^a   Cenedeze, M A ^a   Teixeira, V P A ^b   Reis, M A ^b   Pacheco Silva, A ^a   Camara N O S ^a,c  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Triangulo Mineiro Medical School   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYCLINE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 4; MESSENGER RNA; UREA;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MORTALITY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGENERATION; REPERFUSION INJURY; TISSUE INJURY; UREA BLOOD LEVEL;

ANIMALS; BONE MARROW CELLS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-4; KIDNEY DISEASES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; REPERFUSION INJURY; TREATMENT OUTCOME;

EID: 33847716669     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.01.036     Document Type: Article

References (14)

1. Lin F. Stem cells in kidney regeneration following acute renal injury. Pediatr Res 59 (2006) 74R
2. National Institutes of Health. Stem cells handbook. Available from www.stemcell.nhi.com.
3. Bonventre J.V. Mechanisms of ischemic acute renal failure. Kidney Int 43 (1993) 1160
4. Baud L., Haymann J.P., Bellocq A., et al. Contribution of stem cells to renal repair after ischemia/reperfusion. Bull Acad Natl Med 189 (2005) 635
5. Poulsom R., Forbes S.J., Hodivala-Dilke K., et al. Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol 195 (2001) 229
6. Gupta S., Verfaillie C., Chmielewski D., et al. A role for extra-renal cells in the regeneration following acute renal failure. Kidney Int 62 (2002) 1285
7. Duffield J.S., Park K.M., Hsiao L.L., et al. Restoration of tubular epithelial cells during repair of the post-ischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 115 (2005) 1743
8. Kale S., Karihaloo A., Clark P.R., et al. Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. J Clin Invest 112 (2003) 42
9. Morigi M., Imberti B., Zoja C., et al. Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol 15 (2004) 1794
10. Togel F., Hu Z., Weiss K., et al. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 289 (2005) F31
11. Morigi M., Benigni A., Remuzzi G., et al. The regenerative potential of stem cells in acute renal failure. Cell Transplant 1 (2006) S111
12. Humphreys B.D., Duffield J.D., and Bonventre J.V. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol 58 (2006) 13
13. Pittenger M.F., Mackay A.M., Beck S.C., et al. Multi-lineage potential of adult human mesenchymal stem cells. Science 284 (1999) 143
14. Duffield J.S., and Bonventre J.V. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int 68 (2005) 1956