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Volumn 15, Issue 4, 2010, Pages 372-381

Recent advances in combined modality therapy

Author keywords

Chemotherapy; Radiation; Radiosensitization; Targeted therapy

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CELL RECEPTOR; CETUXIMAB; CISPLATIN; CYTOTOXIC AGENT; ENZYME; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; FLUOROURACIL; GEFITINIB; GEMCITABINE; IRINOTECAN; OXALIPLATIN; PACLITAXEL; PROCARBAZINE; TEMOZOLOMIDE;

EID: 77951762464     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2009-S105     Document Type: Article
Times cited : (32)

References (77)
  • 1
    • 0031864830 scopus 로고    scopus 로고
    • Oxaliplatin: Mechanism of action and antineoplastic activity
    • Raymond E, Faivre S, Woynarowski JM et al. Oxaliplatin: Mechanism of action and antineoplastic activity. Semin Oncol 1998;25(suppl 5):4-12.
    • (1998) Semin Oncol , vol.25 , Issue.SUPPL. 5 , pp. 4-12
    • Raymond, E.1    Faivre, S.2    Woynarowski, J.M.3
  • 2
    • 0141954386 scopus 로고    scopus 로고
    • Oxaliplatin: In vitro evidence of its radiation sensitizing activity-preclinical observations relevant to clinical trials
    • Blackstock AW, Hess S, Chaney S et al. Oxaliplatin: In vitro evidence of its radiation sensitizing activity-preclinical observations relevant to clinical trials. Int J Radiat Oncol Biol Phys 1999;46:724.
    • (1999) Int J Radiat Oncol Biol Phys , vol.46 , pp. 724
    • Blackstock, A.W.1    Hess, S.2    Chaney, S.3
  • 3
    • 0028828382 scopus 로고
    • Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers
    • Pendyala L, Kidani Y, Perez R et al. Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers. Cancer Lett 1995;97:177-184.
    • (1995) Cancer Lett , vol.97 , pp. 177-184
    • Pendyala, L.1    Kidani, Y.2    Perez, R.3
  • 4
    • 0000460127 scopus 로고    scopus 로고
    • Oxaliplatin, tetraplatin, cisplatin, and carboplatin: Spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel
    • Rixe O, Ortuzar W, Alvarez M et al. Oxaliplatin, tetraplatin, cisplatin, and carboplatin: Spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel. Biochem Pharmacol 1996;52:1855-1865.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1855-1865
    • Rixe, O.1    Ortuzar, W.2    Alvarez, M.3
  • 5
    • 0030986840 scopus 로고    scopus 로고
    • Comparative cytotoxicity of oxaliplatin and cisplatin in non-seminomatous germ cell cancer cell lines
    • Dunn TA, Schmoll HJ, Grnwald V et al. Comparative cytotoxicity of oxaliplatin and cisplatin in non-seminomatous germ cell cancer cell lines. Invest New Drugs 1997;15:109-114.
    • (1997) Invest New Drugs , vol.15 , pp. 109-114
    • Dunn, T.A.1    Schmoll, H.J.2    Grnwald, V.3
  • 6
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil and leucovorin as adjuvant treatment for colon cancer
    • André T, Boni C, Mounedji-Boudiaf L et al. Oxaliplatin, fluorouracil and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004;350: 2343-2351.
    • (2004) N Engl J Med , vol.350 , pp. 2343-2351
    • André, T.1    Boni, C.2    Mounedji-Boudiaf, L.3
  • 7
    • 33745005080 scopus 로고    scopus 로고
    • Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901
    • Ryan DP, Niedzwiecki D, Hollis D et al. Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901. J Clin Oncol 2006;24:2557-2562.
    • (2006) J Clin Oncol , vol.24 , pp. 2557-2562
    • Ryan, D.P.1    Niedzwiecki, D.2    Hollis, D.3
  • 8
    • 34648814228 scopus 로고    scopus 로고
    • Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer: A phase I-II multicenter study of the Dutch Colorectal Cancer Group
    • Hospers GA, Punt CJ, Tesselaar ME et al. Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer: A phase I-II multicenter study of the Dutch Colorectal Cancer Group. Ann Surg Oncol 2007;14:2773-2779.
    • (2007) Ann Surg Oncol , vol.14 , pp. 2773-2779
    • Hospers, G.A.1    Punt, C.J.2    Tesselaar, M.E.3
  • 9
    • 77951748036 scopus 로고    scopus 로고
    • Multicenter phase II trial of preoperative radiotherapy with concurrent and adjuvant capecitabine and oxaliplatin in locally advanced rectal cancer
    • Roedel C, Arnold D, Hipp M et al. Multicenter phase II trial of preoperative radiotherapy with concurrent and adjuvant capecitabine and oxaliplatin in locally advanced rectal cancer. J Clin Oncol 2006;24(18 suppl):349.
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL. , pp. 349
    • Roedel, C.1    Arnold, D.2    Hipp, M.3
  • 10
    • 0029792222 scopus 로고    scopus 로고
    • Dependence of 5-fluorouracil mediated radiosensitization on DNA-directed effects
    • Lawrence TS, Davis MA, Maybaum J. Dependence of 5-fluorouracil mediated radiosensitization on DNA-directed effects. Int J Radiat Oncol Biol Phys 1996;70:273-280.
    • (1996) Int J Radiat Oncol Biol Phys , vol.70 , pp. 273-280
    • Lawrence, T.S.1    Davis, M.A.2    Maybaum, J.3
  • 11
    • 0030066442 scopus 로고    scopus 로고
    • Fluorodeoxyuridine-mediated cytotoxicity and radiosensitization requires S phase progression
    • Lawrence TS, Davis MA, Tang TY et al. Fluorodeoxyuridine-mediated cytotoxicity and radiosensitization requires S phase progression. Int J Radiat Oncol Biol Phys 1996;34:617-621.
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , pp. 617-621
    • Lawrence, T.S.1    Davis, M.A.2    Tang, T.Y.3
  • 12
    • 0032695102 scopus 로고    scopus 로고
    • X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts
    • Sawada N, Ishikawa T, Sekiguchi F et al. X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts. Clin Cancer Res 1999;5:2948-2953.
    • (1999) Clin Cancer Res , vol.5 , pp. 2948-2953
    • Sawada, N.1    Ishikawa, T.2    Sekiguchi, F.3
  • 13
    • 33244485826 scopus 로고    scopus 로고
    • Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: Expression analysis of genes related to outcome
    • Saif MW, Eloubeidi MA, Russo S et al. Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: Expression analysis of genes related to outcome. J Clin Oncol 2005; 23:8679-8687.
    • (2005) J Clin Oncol , vol.23 , pp. 8679-8687
    • Saif, M.W.1    Eloubeidi, M.A.2    Russo, S.3
  • 14
    • 27744498513 scopus 로고    scopus 로고
    • Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer
    • Schneider BJ, Ben-Josef E, McGinn CJ et al. Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 2005;63:1325-1330.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 1325-1330
    • Schneider, B.J.1    Ben-Josef, E.2    McGinn, C.J.3
  • 15
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • Dunst J, Reese T, Sutter T et al. Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. J Clin Oncol 2002;20:3983-3991.
    • (2002) J Clin Oncol , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3
  • 16
    • 0028240063 scopus 로고
    • Metabolism of 2,2 -difluoro-2 -deoxycytidine and radiation sensitization of human colon carcinoma cells
    • Shewach DS, Hahn TM, Chang E et al. Metabolism of 2,2 -difluoro-2 -deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Res 1994;54:3218-3223.
    • (1994) Cancer Res , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3
  • 17
    • 0026984625 scopus 로고
    • Effect of 2,2 -difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro
    • Rockwell S, Grindley GB. Effect of 2,2 -difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro. Oncol Res 1992;4:151-155.
    • (1992) Oncol Res , vol.4 , pp. 151-155
    • Rockwell, S.1    Grindley, G.B.2
  • 18
    • 0030005273 scopus 로고    scopus 로고
    • Radiosensitization of pancreatic cancer cells by 2,2 -difluoro-2 -deoxycytidine
    • Lawrence TS, Chang EY, Hahn TM et al. Radiosensitization of pancreatic cancer cells by 2,2 -difluoro-2 -deoxycytidine. Int J Radiat Oncol Biol Phys 1996;34:867-872.
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , pp. 867-872
    • Lawrence, T.S.1    Chang, E.Y.2    Hahn, T.M.3
  • 19
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA 3rd, Moore MJ, Andersen J et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 20
    • 48949101462 scopus 로고    scopus 로고
    • A randomized phase III study of gemcitabine in combination with radiation therapy versus gemcitabine alone in patients with localized unresectable pancreatic cancer
    • Loehrer PJ, Powell ME, Cardenes L et al. A randomized phase III study of gemcitabine in combination with radiation therapy versus gemcitabine alone in patients with localized unresectable pancreatic cancer. J Clin Oncol 2008;26(15 suppl):4506.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL. , pp. 4506
    • Loehrer, P.J.1    Powell, M.E.2    Cardenes, L.3
  • 21
    • 50849115450 scopus 로고    scopus 로고
    • Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000-01 FFCD/SFRO study
    • Chauffert B, Mornex F, Bonnetain F et al. Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000-01 FFCD/SFRO study. Ann Oncol 2008;19:1592-1599.
    • (2008) Ann Oncol , vol.19 , pp. 1592-1599
    • Chauffert, B.1    Mornex, F.2    Bonnetain, F.3
  • 22
    • 0034880820 scopus 로고    scopus 로고
    • Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma
    • Wolff RA, Evans DB, Gravel DM et al. Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma. Clin Cancer Res 2001;7:2246-2253.
    • (2001) Clin Cancer Res , vol.7 , pp. 2246-2253
    • Wolff, R.A.1    Evans, D.B.2    Gravel, D.M.3
  • 23
    • 1342289781 scopus 로고    scopus 로고
    • Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer
    • Muler JH, McGinn CJ, Normolle D et al. Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer. J Clin Oncol 2004;22:238-243.
    • (2004) J Clin Oncol , vol.22 , pp. 238-243
    • Muler, J.H.1    McGinn, C.J.2    Normolle, D.3
  • 24
    • 35648954155 scopus 로고    scopus 로고
    • Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer
    • Desai SP, Ben-Josef E, Normolle DP et al. Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer. J Clin Oncol 2007;25:4587-4592.
    • (2007) J Clin Oncol , vol.25 , pp. 4587-4592
    • Desai, S.P.1    Ben-Josef, E.2    Normolle, D.P.3
  • 25
    • 34249332089 scopus 로고    scopus 로고
    • Full-dose gemcitabine and concurrent radiotherapy for unresectable pancreatic cancer
    • Murphy JD, Adusumilli S, Griffith KA et al. Full-dose gemcitabine and concurrent radiotherapy for unresectable pancreatic cancer. Int J Radiat Oncol Biol Phys 2007;68:801-808.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 801-808
    • Murphy, J.D.1    Adusumilli, S.2    Griffith, K.A.3
  • 26
    • 68649128785 scopus 로고    scopus 로고
    • Phase I radiation dose-escalation trial of intensity modulated radiotherapy (IMRT) with concurrent fixed dose-rate gemcitabine (FDR-G) for unresectable pancreatic cancer
    • Ben-Josef E, Griffith K, Francis IR et al. Phase I radiation dose-escalation trial of intensity modulated radiotherapy (IMRT) with concurrent fixed dose-rate gemcitabine (FDR-G) for unresectable pancreatic cancer. J Clin Oncol 2009;27(15 suppl):4602.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL. , pp. 4602
    • Ben-Josef, E.1    Griffith, K.2    Francis, I.R.3
  • 27
    • 40449113435 scopus 로고    scopus 로고
    • Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: A randomized controlled trial
    • Regine WF, Winter KA, Abrams RA et al. Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: A randomized controlled trial. JAMA 2008;299:1019-1026.
    • (2008) JAMA , vol.299 , pp. 1019-1026
    • Regine, W.F.1    Winter, K.A.2    Abrams, R.A.3
  • 28
    • 3242667277 scopus 로고    scopus 로고
    • Adjuvant therapy in pancreatic cancer: Phase I trial of radiation dose escalation with concurrent full-dose gemcitabine
    • Allen AM, Zalupski MM, Robertson JM et al. Adjuvant therapy in pancreatic cancer: Phase I trial of radiation dose escalation with concurrent full-dose gemcitabine. Int J Radiat Oncol Biol Phys 2004;59:1461-1467.
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 1461-1467
    • Allen, A.M.1    Zalupski, M.M.2    Robertson, J.M.3
  • 29
    • 52549124954 scopus 로고    scopus 로고
    • Induction chemotherapy with cisplatin and gemcitabine followed by concurrent chemoradiation with twice-weekly gemcitabine in unresectable stage III non-small cell lung cancer: Final results of a phase II study
    • Blanco R, Solé J, Montesinos J et al. Induction chemotherapy with cisplatin and gemcitabine followed by concurrent chemoradiation with twice-weekly gemcitabine in unresectable stage III non-small cell lung cancer: Final results of a phase II study. Lung Cancer 2008;62:62-71.
    • (2008) Lung Cancer , vol.62 , pp. 62-71
    • Blanco, R.1    Solé, J.2    Montesinos, J.3
  • 30
    • 45149128875 scopus 로고    scopus 로고
    • Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105
    • Socinski MA, Blackstock AW, Bogart JA et al. Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105. J Clin Oncol 2008;26:2457-2463.
    • (2008) J Clin Oncol , vol.26 , pp. 2457-2463
    • Socinski, M.A.1    Blackstock, A.W.2    Bogart, J.A.3
  • 31
    • 61549108337 scopus 로고    scopus 로고
    • RTOG 0017: A phase I trial of concurrent gemcitabine/carboplatin or gemcitabine/paclitaxel and radiation therapy ("ping-pong trial") followed by adjuvant chemotherapy for patients with favorable prognosis inoperable stage IIIA/B non-small cell lung cancer
    • Choy H, Jain AK, Moughan J et al. RTOG 0017: A phase I trial of concurrent gemcitabine/carboplatin or gemcitabine/paclitaxel and radiation therapy ("ping-pong trial") followed by adjuvant chemotherapy for patients with favorable prognosis inoperable stage IIIA/B non-small cell lung cancer. J Thorac Oncol 2009;4:80-86.
    • (2009) J Thorac Oncol , vol.4 , pp. 80-86
    • Choy, H.1    Jain, A.K.2    Moughan, J.3
  • 32
    • 68349116963 scopus 로고    scopus 로고
    • High frequency of radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent radiotherapy and gemcitabine after induction gemcitabine and carboplatin
    • Arrieta O, Gallardo-Rincón D, Villarreal-Garza C et al. High frequency of radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent radiotherapy and gemcitabine after induction gemcitabine and carboplatin. J Thorac Oncol 2009;4:845-852.
    • (2009) J Thorac Oncol , vol.4 , pp. 845-852
    • Arrieta, O.1    Gallardo-Rincón, D.2    Villarreal-Garza, C.3
  • 33
    • 57649088626 scopus 로고    scopus 로고
    • Dose escalation of gemcitabine is possible with concurrent chest three-dimensional rather than two-dimensional radiotherapy: A phase I trial in patients with stage III non-small cell lung cancer
    • Zinner RG, Komaki R, Cox JD et al. Dose escalation of gemcitabine is possible with concurrent chest three-dimensional rather than two-dimensional radiotherapy: A phase I trial in patients with stage III non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2009;73:119-127.
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 119-127
    • Zinner, R.G.1    Komaki, R.2    Cox, J.D.3
  • 34
    • 0028169689 scopus 로고
    • 3 -(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin
    • Rao S, Krauss NE, Heerding JM et al. 3 -(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin. J Biol Chem 1994; 269:3132-3134.
    • (1994) J Biol Chem , vol.269 , pp. 3132-3134
    • Rao, S.1    Krauss, N.E.2    Heerding, J.M.3
  • 35
    • 0021229643 scopus 로고
    • Taxol: An antimitotic agent with a new mechanism of action
    • Manfredt JJ, Horwitz SB. Taxol: An antimitotic agent with a new mechanism of action. Pharmacol Ther 1984;25:83-125.
    • (1984) Pharmacol Ther , vol.25 , pp. 83-125
    • Manfredt, J.J.1    Horwitz, S.B.2
  • 36
    • 0029144003 scopus 로고
    • Role of reoxygenation in induction of enhancement of tumor response by paclitaxel
    • Milas L, Hunter NR, Mason KA et al. Role of reoxygenation in induction of enhancement of tumor response by paclitaxel. Cancer Res 1995;55:3564-3568.
    • (1995) Cancer Res , vol.55 , pp. 3564-3568
    • Milas, L.1    Hunter, N.R.2    Mason, K.A.3
  • 37
    • 34249111679 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity
    • Feng FY, Varambally S, Tomlins SA et al. Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity. Oncogene 2007;26:3431-3439.
    • (2007) Oncogene , vol.26 , pp. 3431-3439
    • Feng, F.Y.1    Varambally, S.2    Tomlins, S.A.3
  • 38
    • 24944542868 scopus 로고    scopus 로고
    • Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non-small-cell lung cancer: A randomized phase II locally advanced multi-modality protocol
    • Belani CP, Choy H, Bonomi P et al. Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non-small-cell lung cancer: A randomized phase II locally advanced multi-modality protocol. J Clin Oncol 2005;23:5883-5891.
    • (2005) J Clin Oncol , vol.23 , pp. 5883-5891
    • Belani, C.P.1    Choy, H.2    Bonomi, P.3
  • 39
    • 0000676381 scopus 로고    scopus 로고
    • Induction chemotherapy with paclitaxel and carboplatin followed by concurrent thoracic radiotherapy and weekly PC for patients with unresectable stage III non-small cell lung cancer: Preliminary analysis of a phase II trial by the CALGB [abstract 1915]
    • Akerley BW, Herndon J, Turrisi AT et al. Induction chemotherapy with paclitaxel and carboplatin followed by concurrent thoracic radiotherapy and weekly PC for patients with unresectable stage III non-small cell lung cancer: Preliminary analysis of a phase II trial by the CALGB [abstract 1915]. Proc Am Soc Clin Oncol 2000;19.
    • (2000) Proc Am Soc Clin Oncol , pp. 19
    • Akerley, B.W.1    Herndon, J.2    Turrisi, A.T.3
  • 40
    • 10844240941 scopus 로고    scopus 로고
    • Induction chemotherapy followed by concomitant chemoradiotherapy (CT/XRT) versus CT/XRT alone for regionally advanced unresectable non-small cell lung cancer: Initial analysis of a randomized phase III trial
    • Vokes EE, Herndon J, Kelley MJ et al. Induction chemotherapy followed by concomitant chemoradiotherapy (CT/XRT) versus CT/XRT alone for regionally advanced unresectable non-small cell lung cancer: Initial analysis of a randomized phase III trial. J Clin Oncol 2004;22(14 suppl):7005.
    • (2004) J Clin Oncol , vol.22 , Issue.14 SUPPL. , pp. 7005
    • Vokes, E.E.1    Herndon, J.2    Kelley, M.J.3
  • 41
    • 34548541943 scopus 로고    scopus 로고
    • Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cellcarcinomas of the larynx or oropharynx: Results of Eastern Cooperative Oncology Group Study E2399
    • Cmelak AJ, Li S, Goldwasser MA et al. Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cellcarcinomas of the larynx or oropharynx: Results of Eastern Cooperative Oncology Group Study E2399. J Clin Oncol 2007;25:3971-3977.
    • (2007) J Clin Oncol , vol.25 , pp. 3971-3977
    • Cmelak, A.J.1    Li, S.2    Goldwasser, M.A.3
  • 42
    • 34547852264 scopus 로고    scopus 로고
    • Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer
    • Agarwala SS, Cano E, Heron DE et al. Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer. Ann Oncol 2007;18:1224-1229.
    • (2007) Ann Oncol , vol.18 , pp. 1224-1229
    • Agarwala, S.S.1    Cano, E.2    Heron, D.E.3
  • 43
    • 41649090652 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy with weekly paclitaxel and carboplatin for locally advanced head and neck caner: Long-term follow-up of a Brown University Oncology Group phase II study (HN-53)
    • Chougule PB, Akhtar MS, Rathore R et al. Concurrent chemoradiotherapy with weekly paclitaxel and carboplatin for locally advanced head and neck caner: Long-term follow-up of a Brown University Oncology Group phase II study (HN-53). Head Neck 2008;30:289-296.
    • (2008) Head Neck , vol.30 , pp. 289-296
    • Chougule, P.B.1    Akhtar, M.S.2    Rathore, R.3
  • 44
    • 53049103005 scopus 로고    scopus 로고
    • Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: A multi-institutional phase II trial investigating three radiotherapy dose levels
    • Salama JK, Stenson KM, Kistner EO et al. Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: A multi-institutional phase II trial investigating three radiotherapy dose levels. Ann Oncol 2008;19:1787-1794.
    • (2008) Ann Oncol , vol.19 , pp. 1787-1794
    • Salama, J.K.1    Stenson, K.M.2    Kistner, E.O.3
  • 45
    • 33847364433 scopus 로고    scopus 로고
    • MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
    • Donson AM, Addo-Yobo SO, Handler MH et al. MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma. Pediatr Blood Cancer 2007;48:403-407.
    • (2007) Pediatr Blood Cancer , vol.48 , pp. 403-407
    • Donson, A.M.1    Addo-Yobo, S.O.2    Handler, M.H.3
  • 46
    • 0029011186 scopus 로고
    • Activity of temozolomide in the treatment of central nervous system tumor xenografts
    • Friedman HS, Dolan ME, Pegg AE et al. Activity of temozolomide in the treatment of central nervous system tumor xenografts. Cancer Res 1995;55:2853-2857.
    • (1995) Cancer Res , vol.55 , pp. 2853-2857
    • Friedman, H.S.1    Dolan, M.E.2    Pegg, A.E.3
  • 47
    • 0030911619 scopus 로고    scopus 로고
    • Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: An evaluation in a human melanoma xenograft model
    • Wedge SR, Porteous JK, Newlands ES. Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: An evaluation in a human melanoma xenograft model. Cancer Chemother Pharmacol 1997;40:266-272.
    • (1997) Cancer Chemother Pharmacol , vol.40 , pp. 266-272
    • Wedge, S.R.1    Porteous, J.K.2    Newlands, E.S.3
  • 48
    • 0033897173 scopus 로고    scopus 로고
    • A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
    • Yung WK, Albright RE, Olson J et al. A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 2000;83:588-593.
    • (2000) Br J Cancer , vol.83 , pp. 588-593
    • Yung, W.K.1    Albright, R.E.2    Olson, J.3
  • 49
    • 0036499085 scopus 로고    scopus 로고
    • Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide
    • Stupp R, Dietrich PY, Ostermann Kraljevic S et al. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol 2002;20:1375-1382.
    • (2002) J Clin Oncol , vol.20 , pp. 1375-1382
    • Stupp, R.1    Dietrich, P.Y.2    Ostermann Kraljevic, S.3
  • 50
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 51
    • 55549112218 scopus 로고    scopus 로고
    • Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases
    • Addeo R, De Rosa C, Faiola V et al. Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases. Cancer 2008;113:2524-2531.
    • (2008) Cancer , vol.113 , pp. 2524-2531
    • Addeo, R.1    de Rosa, C.2    Faiola, V.3
  • 52
    • 49249095295 scopus 로고    scopus 로고
    • EGFR, p16, HPV titer, Bcl-xL and p53, sex and smoking as indicators of response to therapy and survival in oropharyngeal cancer
    • Kumar B, Cordell KG, Lee JS et al. EGFR, p16, HPV titer, Bcl-xL and p53, sex and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol 2008;26:3128-3137.
    • (2008) J Clin Oncol , vol.26 , pp. 3128-3137
    • Kumar, B.1    Cordell, K.G.2    Lee, J.S.3
  • 53
    • 20044387209 scopus 로고    scopus 로고
    • Prognostic impact of the epidermal growth factor rector levels for patients with larynx and hypopharynx cancer
    • Pivot X, Magné N, Guardiola E et al. Prognostic impact of the epidermal growth factor rector levels for patients with larynx and hypopharynx cancer. Oral Oncol 2005;41:320-327.
    • (2005) Oral Oncol , vol.41 , pp. 320-327
    • Pivot, X.1    Magné, N.2    Guardiola, E.3
  • 54
    • 33750357154 scopus 로고    scopus 로고
    • Integration of EGFR inhibitors with radiochemotherapy
    • Nyati MK, Morgan MA, Feng FY et al. Integration of EGFR inhibitors with radiochemotherapy. Nat Rev Cancer 2006;6:876-885.
    • (2006) Nat Rev Cancer , vol.6 , pp. 876-885
    • Nyati, M.K.1    Morgan, M.A.2    Feng, F.Y.3
  • 55
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Eng J Med 2006;354:567-578.
    • (2006) N Eng J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 56
    • 44649168832 scopus 로고    scopus 로고
    • A brief report on the safety of induction chemotherapy followed by synchronous radiotherapy and cetuximab in stage III non-small cell lung cancer (NSCLC): SCRATCH study
    • Hughes S, Liong J, Miah A et al. A brief report on the safety of induction chemotherapy followed by synchronous radiotherapy and cetuximab in stage III non-small cell lung cancer (NSCLC): SCRATCH study. J Thor Oncol 2008;3:648-651.
    • (2008) J Thor Oncol , vol.3 , pp. 648-651
    • Hughes, S.1    Liong, J.2    Miah, A.3
  • 57
    • 33746602232 scopus 로고    scopus 로고
    • Treatment of non-small cell lung cancer with intensity-modulated radiation therapy in combination with cetuximab: The NEAR protocol (NCT00115518)
    • Jensen AD, Munter MW, Bischoff H et al. Treatment of non-small cell lung cancer with intensity-modulated radiation therapy in combination with cetuximab: The NEAR protocol (NCT00115518). BMC Cancer 2006;6:122.
    • (2006) BMC Cancer , vol.6 , pp. 122
    • Jensen, A.D.1    Munter, M.W.2    Bischoff, H.3
  • 58
    • 67650867224 scopus 로고    scopus 로고
    • Final results of a phase II trial for patients with primary inoperable locally advanced pancreatic cancer combining intensity modulated radiotherapy (IMRT) with cetuximab and gemcitabine
    • Munter M, Timke C, Abdollahi A et al. Final results of a phase II trial for patients with primary inoperable locally advanced pancreatic cancer combining intensity modulated radiotherapy (IMRT) with cetuximab and gemcitabine. J Clin Oncol 2008;26(15 suppl):4613.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL. , pp. 4613
    • Munter, M.1    Timke, C.2    Abdollahi, A.3
  • 59
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008;359: 1757-1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 60
    • 31544464043 scopus 로고    scopus 로고
    • Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma
    • Chun PY, Feng FY, Scheurer AM et al. Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma. Cancer Res 2006;66:981-988.
    • (2006) Cancer Res , vol.66 , pp. 981-988
    • Chun, P.Y.1    Feng, F.Y.2    Scheurer, A.M.3
  • 61
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 1
    • Giaccone G, Herbst RS, Manegold C et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 1. J Clin Oncol 2004;22:777-784.
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 62
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 2
    • Herbst RS, Giaccone G, Schiller JH et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 2. J Clin Oncol 2004;22:785-794.
    • (2004) J Clin Oncol , vol.22 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 63
    • 63049115966 scopus 로고    scopus 로고
    • The "lazarus response" in treatment-naive, poor performance status patients with non-small-cell lung cancer and epidermal growth factor receptor mutation
    • Langer CJ. The "lazarus response" in treatment-naive, poor performance status patients with non-small-cell lung cancer and epidermal growth factor receptor mutation. J Clin Oncol 2009;27:1350-1354.
    • (2009) J Clin Oncol , vol.27 , pp. 1350-1354
    • Langer, C.J.1
  • 64
    • 67449127097 scopus 로고    scopus 로고
    • Role of cell cycle in epidermal growth factor receptor inhibitor-mediated radiosensitization
    • Ahsan A, Hiniker SM, Davis MA et al. Role of cell cycle in epidermal growth factor receptor inhibitor-mediated radiosensitization. Cancer Res 2009;69:5108-5114.
    • (2009) Cancer Res , vol.69 , pp. 5108-5114
    • Ahsan, A.1    Hiniker, S.M.2    Davis, M.A.3
  • 65
    • 43249088259 scopus 로고    scopus 로고
    • Induction chemotherapy with carboplatin, irinotecan, and paclitaxel followed by high dose three-dimensional conformal thoracic radiotherapy with concurrent carboplatin, paclitaxel, and gefitinib in unresectable stage IIIA and stage IIIB non-small cell lung cancer
    • Stinchcombe TE, Morris DE, Lee CB et al. Induction chemotherapy with carboplatin, irinotecan, and paclitaxel followed by high dose three-dimensional conformal thoracic radiotherapy with concurrent carboplatin, paclitaxel, and gefitinib in unresectable stage IIIA and stage IIIB non-small cell lung cancer. J Thorac Oncol 2008;3:250-257.
    • (2008) J Thorac Oncol , vol.3 , pp. 250-257
    • Stinchcombe, T.E.1    Morris, D.E.2    Lee, C.B.3
  • 66
    • 44649128868 scopus 로고    scopus 로고
    • Updated results of a phase II trial integrating gefitinib into concurrent chemoradiation followed by G adjuvant therapy for locally advanced head and neck cancer
    • Ahmed SM, Cohen EE, Haraf DJ et al. Updated results of a phase II trial integrating gefitinib into concurrent chemoradiation followed by G adjuvant therapy for locally advanced head and neck cancer. J Clin Oncol 2007; 25(18 suppl):6028.
    • (2007) J Clin Oncol , vol.25 , Issue.18 SUPPL. , pp. 6028
    • Ahmed, S.M.1    Cohen, E.E.2    Haraf, D.J.3
  • 67
    • 77951756526 scopus 로고    scopus 로고
    • Feasibility study of erlotinib plus radiotherapy in patients with locally advanced or recurrent rectal carcinoma [abstract 153]
    • Van Triest B, Kuenen B, Ghotra V et al. Feasibility study of erlotinib plus radiotherapy in patients with locally advanced or recurrent rectal carcinoma [abstract 153]. Int J Radiat Oncol Biol Phys 2008;72 (suppl 1):S69.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , Issue.SUPPL. 1
    • van Triest, B.1    Kuenen, B.2    Ghotra, V.3
  • 68
    • 57149118473 scopus 로고    scopus 로고
    • Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177
    • Brown PD, Krishnan S, Sarkaria JN et al. Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177. J Clin Oncol 2008;26:5603-5609.
    • (2008) J Clin Oncol , vol.26 , pp. 5603-5609
    • Brown, P.D.1    Krishnan, S.2    Sarkaria, J.N.3
  • 69
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Goldstein D, Hamm J et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007;25:1960-1966.
    • (2007) J Clin Oncol , vol.25 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 70
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • Willett CG, Boucher Y, di Tomaso E et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004;10:145-147.
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    di Tomaso, E.3
  • 71
    • 57849102707 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant bevacizumab, capecitabine and radiotherapy for locally advanced rectal cancer
    • Crane CH, Eng C, Feig BW et al. Phase II trial of neoadjuvant bevacizumab, capecitabine and radiotherapy for locally advanced rectal cancer. J Clin Oncol 2008;26(15 suppl):4091.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL. , pp. 4091
    • Crane, C.H.1    Eng, C.2    Feig, B.W.3
  • 72
    • 77951709362 scopus 로고    scopus 로고
    • Radiotherapy, temozolomide and bevacizumab followed by irinotecan, temozolomide and bevacizumab in newly diagnosed glioblastoma mutliforme: Preliminary results from an ongoing phase II trial [abstract 2089]
    • Kirkpatrick JP, Desjardins A, Reardon DA et al. Radiotherapy, temozolomide and bevacizumab followed by irinotecan, temozolomide and bevacizumab in newly diagnosed glioblastoma mutliforme: Preliminary results from an ongoing phase II trial [abstract 2089]. Int J Radiat Oncol Biol Phys 2008;72(1 suppl):S209.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , Issue.1 SUPPL.
    • Kirkpatrick, J.P.1    Desjardins, A.2    Reardon, D.A.3
  • 73
    • 77951742970 scopus 로고    scopus 로고
    • A phase II trial of weekly gemcitabine and bevacizumab in combination with abdominal radiation therapy in patients with localized pancreatic cancer [abstract 13]
    • Small W, Mulcahy M, Rademaker A et al. A phase II trial of weekly gemcitabine and bevacizumab in combination with abdominal radiation therapy in patients with localized pancreatic cancer [abstract 13]. Int J Radiat Oncol Biol Phys 2008;72(1 suppl):S6.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , Issue.1 SUPPL.
    • Small, W.1    Mulcahy, M.2    Rademaker, A.3
  • 74
    • 53949100896 scopus 로고    scopus 로고
    • Preoperative gemcitabine and bevacizumab-based chemoradiation for resectable pancreatic adenocarcinoma
    • Varadhachary GR, Wolff RA, Crane CH et al. Preoperative gemcitabine and bevacizumab-based chemoradiation for resectable pancreatic adenocarcinoma. J Clin Oncol 2008;26(15 suppl):4630.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL. , pp. 4630
    • Varadhachary, G.R.1    Wolff, R.A.2    Crane, C.H.3
  • 75
    • 33644968548 scopus 로고    scopus 로고
    • Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer
    • Crane CH, Ellis LM, Abbruzzese JL et al. Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol 2006;24:1145-1151.
    • (2006) J Clin Oncol , vol.24 , pp. 1145-1151
    • Crane, C.H.1    Ellis, L.M.2    Abbruzzese, J.L.3
  • 76
    • 52649108603 scopus 로고    scopus 로고
    • The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer
    • Morgan MA, Parsels LA, Kollar LE et al. The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer. Clin Cancer Res 2008;14:5142-5149.
    • (2008) Clin Cancer Res , vol.14 , pp. 5142-5149
    • Morgan, M.A.1    Parsels, L.A.2    Kollar, L.E.3
  • 77
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 2003;21:2787-2799.
    • (2003) J Clin Oncol , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2


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