Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000-01 FFCD/SFRO study

Annals of Oncology

Volumn 19, Issue 9, 2008, Pages 1592-1599

  Chauffert, B ^a   Mornex, F ^b   Bonnetain, F ^c,o   Rougier, P ^d   Mariette, C ^e   Bouche O ^f   Bosset, J F ^g   Aparicio, T ^h   Mineur, L ⁱ   Azzedine, A ^j   Hammel, P ^k   Butel, J ^l   Stremsdoerfer, N ^m   Maingon, P ^a   Bedenne, L ⁿ  

^a Centre Anti Cancer GF Leclerc   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c Statistics Department   (France)

^d HÔPITAL AMBROISE PARÉ   (France)

^e Lille1 University   (France)

^f REIMS UNIVERSITY HOSPITAL   (France)

^g UNIVERSITY HOSPITAL OF BESANÇON   (France)

^h BICHAT HOSPITAL   (France)

ⁱ Sainte Catherine Institute   (France)

^j CENTRE HOSPITALIER D AVIGNON   (France)

^k BEAUJON HOSPITAL   (France)

^l Abbeville Hospital   (France)

^m CHP Oudot   (France)

ⁿ DIJON UNIVERSITY HOSPITAL   (France)

^o INSERM   (France)

more..

Author keywords

5 fluorouracil; Chemoradiotherapy; Cisplatin; Gemcitabine; Maintenance; Overall survival; Pancreatic cancer; Randomized phase III trial

Indexed keywords

CISPLATIN; FLUOROURACIL; GEMCITABINE;

ADULT; ADVANCED CANCER; AGED; ANEMIA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG INTERMITTENT THERAPY; FEBRILE NEUTROPENIA; FEMALE; HUMAN; INFECTION; INOPERABLE CANCER; KIDNEY DISEASE; LEUKOPENIA; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTIMODALITY CANCER THERAPY; NAUSEA AND VOMITING; NEUROTOXICITY; NEUTROPENIA; OVERALL SURVIVAL; PANCREAS CANCER; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION DOSE; RANDOMIZED CONTROLLED TRIAL; SKIN DISEASE; STOMATITIS; SURVIVAL TIME; THROMBOCYTOPENIA; UNSPECIFIED SIDE EFFECT;

EID: 50849115450     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn281     Document Type: Article

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