메뉴 건너뛰기




Volumn 40, Issue 5, 2010, Pages 1396-1407

Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells

Author keywords

CD127; CD8+ T cells; IL 4; IL 7; Thymocytes

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; MESSENGER RNA; STAT5 PROTEIN;

EID: 77951741877     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940093     Document Type: Article
Times cited : (18)

References (64)
  • 1
    • 0038655228 scopus 로고    scopus 로고
    • Cytokine control of memory T-cell development and survival
    • Schluns, K. S. and Lefrancois, L., Cytokine control of memory T-cell development and survival. Nat. Rev. Immunol. 2003. 3: 269-279.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 269-279
    • Schluns, K.S.1    Lefrancois, L.2
  • 3
    • 0034283945 scopus 로고    scopus 로고
    • An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire
    • Hare, K. J., Jenkinson, E. J. and Anderson, G., An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire. J. Immunol. 2000. 165: 2410-2414.
    • (2000) J. Immunol. , vol.165 , pp. 2410-2414
    • Hare, K.J.1    Jenkinson, E.J.2    Anderson, G.3
  • 4
    • 32044457728 scopus 로고    scopus 로고
    • Increased plasma Interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection
    • Sasson, S. C., Zaunders, J. J., Zanetti, G., King, E. M., Merlin, K. M., Smith, D. E., Stanley, K. K. et al., Increased plasma Interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection. J. Infect. Dis. 2006. 193: 505-514.
    • (2006) J. Infect. Dis. , vol.193 , pp. 505-514
    • Sasson, S.C.1    Zaunders, J.J.2    Zanetti, G.3    King, E.M.4    Merlin, K.M.5    Smith, D.E.6    Stanley, K.K.7
  • 5
    • 0035894221 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy
    • MacPherson, P. A., Fex, C., Sanchez-Dardon, J., Hawley-Foss, N. and Angel, J. B., Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 2001. 28: 454-457.
    • (2001) J. Acquir. Immune Defic. Syndr. , vol.28 , pp. 454-457
    • MacPherson, P.A.1    Fex, C.2    Sanchez-Dardon, J.3    Hawley-Foss, N.4    Angel, J.B.5
  • 6
    • 27944461008 scopus 로고    scopus 로고
    • Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV
    • Boutboul, F., Puthier, D., Appay, V., Pelle, O., Ait-Mohand, H., Combadiere, B., Carcelain, G. et al., Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV. Aids 2005. 19: 1981-1986.
    • (2005) Aids , vol.19 , pp. 1981-1986
    • Boutboul, F.1    Puthier, D.2    Appay, V.3    Pelle, O.4    Ait-Mohand, H.5    Combadiere, B.6    Carcelain, G.7
  • 7
    • 33750994934 scopus 로고    scopus 로고
    • Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence
    • Golden-Mason, L., Burton, J. R., Jr., Castelblanco, N., Klarquist, J., Benlloch, S., Wang, C. and Rosen, H. R., Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence. Hepatology 2006. 44: 1098-1109.
    • (2006) Hepatology , vol.44 , pp. 1098-1109
    • Golden-Mason, L.1    Burton Jr., J.R.2    Castelblanco, N.3    Klarquist, J.4    Benlloch, S.5    Wang, C.6    Rosen, H.R.7
  • 8
    • 18644370174 scopus 로고    scopus 로고
    • Cutting edge: Emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help
    • Fuller, M. J., Hildeman, D. A., Sabbaj, S., Gaddis, D. E., Tebo, A. E., Shang, L., Goepfert, P. A. and Zajac, A. J., Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. J. Immunol. 2005. 174: 5926-5930.
    • (2005) J. Immunol. , vol.174 , pp. 5926-5930
    • Fuller, M.J.1    Hildeman, D.A.2    Sabbaj, S.3    Gaddis, D.E.4    Tebo, A.E.5    Shang, L.6    Goepfert, P.A.7    Zajac, A.J.8
  • 9
    • 34548291989 scopus 로고    scopus 로고
    • Reduced numbers of IL-7 receptor (CD127) expressing immune cells and IL-7-signaling defects in peripheral blood from patients with breast cancer
    • Vudattu, N. K., Magalhaes, I., Schmidt, M., Seyfert-Margolis, V. and Maeurer, M. J., Reduced numbers of IL-7 receptor (CD127) expressing immune cells and IL-7-signaling defects in peripheral blood from patients with breast cancer. Int. J. Cancer 2007. 121: 1512-1519.
    • (2007) Int. J. Cancer , vol.121 , pp. 1512-1519
    • Vudattu, N.K.1    Magalhaes, I.2    Schmidt, M.3    Seyfert-Margolis, V.4    Maeurer, M.J.5
  • 10
    • 20044382810 scopus 로고    scopus 로고
    • Loss of CD127 expression defines an expansion of effector CD8+T cells in HIV-infected individuals
    • Paiardini, M., Cervasi, B., Albrecht, H., Muthukumar, A., Dunham, R., Gordon, S., Radziewicz, H. et al., Loss of CD127 expression defines an expansion of effector CD8+T cells in HIV-infected individuals. J. Immunol. 2005. 174: 2900-2909.
    • (2005) J. Immunol. , vol.174 , pp. 2900-2909
    • Paiardini, M.1    Cervasi, B.2    Albrecht, H.3    Muthukumar, A.4    Dunham, R.5    Gordon, S.6    Radziewicz, H.7
  • 11
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park, J. H., Yu, Q., Erman, B., Appelbaum, J. S., Montoya-Durango, D., Grimes, H. L. and Singer, A., Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 2004. 21: 289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, Q.2    Erman, B.3    Appelbaum, J.S.4    Montoya-Durango, D.5    Grimes, H.L.6    Singer, A.7
  • 13
    • 36248954476 scopus 로고    scopus 로고
    • IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD81T cells
    • Vranjkovic, A., Crawley, A. M., Gee, K., Kumar, A. and Angel, J. B., IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD81T cells. Int. Immunol. 2007. 19: 1329-1339.
    • (2007) Int. Immunol. , vol.19 , pp. 1329-1339
    • Vranjkovic, A.1    Crawley, A.M.2    Gee, K.3    Kumar, A.4    Angel, J.B.5
  • 14
    • 33646901608 scopus 로고    scopus 로고
    • Optimization of culture and storage conditions for an in vitro system to evaluate thymocyte phenotype and function
    • Young, C. D. and Angel, J. B., Optimization of culture and storage conditions for an in vitro system to evaluate thymocyte phenotype and function. J. Immunol. Methods 2006. 312: 157-166.
    • (2006) J. Immunol. Methods , vol.312 , pp. 157-166
    • Young, C.D.1    Angel, J.B.2
  • 15
    • 33645072224 scopus 로고    scopus 로고
    • CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - Reversal by highly active anti-retroviral therapy (HAART)
    • Colle, J. H., Moreau, J. L., Fontanet, A., Lambotte, O., Joussemet, M., Delfraissy, J. F. and Theze, J., CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - reversal by highly active anti-retroviral therapy (HAART). Clin. Exp. Immunol. 2006. 143: 398-403.
    • (2006) Clin. Exp. Immunol. , vol.143 , pp. 398-403
    • Colle, J.H.1    Moreau, J.L.2    Fontanet, A.3    Lambotte, O.4    Joussemet, M.5    Delfraissy, J.F.6    Theze, J.7
  • 16
    • 33646874634 scopus 로고    scopus 로고
    • IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes
    • Swainson, L., Verhoeyen, E., Cosset, F. L. and Taylor, N., IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes. J. Immunol. 2006. 176: 6702-6708.
    • (2006) J. Immunol. , vol.176 , pp. 6702-6708
    • Swainson, L.1    Verhoeyen, E.2    Cosset, F.L.3    Taylor, N.4
  • 18
    • 67650590873 scopus 로고    scopus 로고
    • IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection
    • Sereti, I., Dunham, R. M., Spritzler, J., Aga, E., Proschan, M. A., Medvik, K., Battaglia, C. A. et al., IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood 2009. 113: 6304-6314.
    • (2009) Blood , vol.113 , pp. 6304-6314
    • Sereti, I.1    Dunham, R.M.2    Spritzler, J.3    Aga, E.4    Proschan, M.A.5    Medvik, K.6    Battaglia, C.A.7
  • 19
    • 33746690674 scopus 로고    scopus 로고
    • Decreased CD127 expression on T Cells in HIV-1-infected adults receiving antiretroviral therapy with or without intermittent IL-2 therapy
    • Read, S. W., Higgins, J., Metcalf, J. A., Stevens, R. A., Rupert, A., Nason, M. C., Lane, H. C. and Sereti, I., Decreased CD127 expression on T Cells in HIV-1-infected adults receiving antiretroviral therapy with or without intermittent IL-2 therapy. J. Acquir. Immune Defic. Syndr. 2006. 42: 537-544.
    • (2006) J. Acquir. Immune Defic. Syndr. , vol.42 , pp. 537-544
    • Read, S.W.1    Higgins, J.2    Metcalf, J.A.3    Stevens, R.A.4    Rupert, A.5    Nason, M.C.6    Lane, H.C.7    Sereti, I.8
  • 20
    • 30744443482 scopus 로고    scopus 로고
    • IL-7 induces immunological improvement in SIV-infected rhesus macaques under antiviral therapy
    • Beq, S., Nugeyre, M. T., Ho Tsong Fang, R., Gautier, D., Legrand, R., Schmitt, N., Estaquier, J. et al., IL-7 induces immunological improvement in SIV-infected rhesus macaques under antiviral therapy. J. Immunol. 2006. 176: 914-922.
    • (2006) J. Immunol. , vol.176 , pp. 914-922
    • Beq, S.1    Nugeyre, M.T.2    Ho Tsong Fang, R.3    Gautier, D.4    Legrand, R.5    Schmitt, N.6    Estaquier, J.7
  • 21
    • 0037443464 scopus 로고    scopus 로고
    • IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates
    • Fry, T. J., Moniuszko, M., Creekmore, S., Donohue, S. J., Douek, D. C., Giardina, S., Hecht, T. T. et al., IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood 2003. 101: 2294-2299.
    • (2003) Blood , vol.101 , pp. 2294-2299
    • Fry, T.J.1    Moniuszko, M.2    Creekmore, S.3    Donohue, S.J.4    Douek, D.C.5    Giardina, S.6    Hecht, T.T.7
  • 22
    • 33947599886 scopus 로고    scopus 로고
    • The duplicitous effects of interleukin 4 on tumour immunity: How can the same cytokine improve or impair control of tumour growth?
    • Olver, S., Apte, S., Baz, A. and Kienzle, N., The duplicitous effects of interleukin 4 on tumour immunity: how can the same cytokine improve or impair control of tumour growth? Tissue Antigens 2007. 69: 293-298.
    • (2007) Tissue Antigens , vol.69 , pp. 293-298
    • Olver, S.1    Apte, S.2    Baz, A.3    Kienzle, N.4
  • 23
    • 13544266571 scopus 로고    scopus 로고
    • Progressive differentiation and commitment of CD8+T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4
    • Kienzle, N., Olver, S., Buttigieg, K., Groves, P., Janas, M. L., Baz, A. and Kelso, A., Progressive differentiation and commitment of CD8+T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4. J. Immunol. 2005. 174: 2021-2029.
    • (2005) J. Immunol. , vol.174 , pp. 2021-2029
    • Kienzle, N.1    Olver, S.2    Buttigieg, K.3    Groves, P.4    Janas, M.L.5    Baz, A.6    Kelso, A.7
  • 25
    • 32944465821 scopus 로고    scopus 로고
    • Autocrine production of interleukin-4 and interleukin-10 is required for survival and growth of thyroid cancer cells
    • Todaro, M., Zerilli, M., Ricci-Vitiani, L., Bini, M., Perez Alea, M., Maria Florena, A., Miceli, L. et al., Autocrine production of interleukin-4 and interleukin-10 is required for survival and growth of thyroid cancer cells. Cancer Res. 2006. 66: 1491-1499.
    • (2006) Cancer Res. , vol.66 , pp. 1491-1499
    • Todaro, M.1    Zerilli, M.2    Ricci-Vitiani, L.3    Bini, M.4    Perez Alea, M.5    Maria Florena, A.6    Miceli, L.7
  • 26
    • 0036786349 scopus 로고    scopus 로고
    • Differential regulation of interleukin (IL)-4, IL-5, and IL-10 during measles in Zambian children
    • Moss,W. J., Ryon, J. J., Monze, M. and Griffin, D. E., Differential regulation of interleukin (IL)-4, IL-5, and IL-10 during measles in Zambian children. J. Infect. Dis. 2002. 186: 879-887.
    • (2002) J. Infect. Dis. , vol.186 , pp. 879-887
    • Moss, W.J.1    Ryon, J.J.2    Monze, M.3    Griffin, D.E.4
  • 28
    • 0028110057 scopus 로고
    • Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus
    • Tang, Y. W. and Graham, B. S., Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus. J. Clin. Invest. 1994. 94: 1953-1958.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1953-1958
    • Tang, Y.W.1    Graham, B.S.2
  • 29
    • 0028275847 scopus 로고
    • Increased levels of interferon-gamma (IFN-gamma), IL-4 and transforming growth factorbeta (TGF-beta) mRNA expressing blood mononuclear cells in human HIV infection
    • Navikas, V., Link, J.,Wahren, B., Persson, C. and Link, H., Increased levels of interferon-gamma (IFN-gamma), IL-4 and transforming growth factorbeta (TGF-beta) mRNA expressing blood mononuclear cells in human HIV infection. Clin. Exp. Immunol. 1994. 96: 59-63.
    • (1994) Clin. Exp. Immunol. , vol.96 , pp. 59-63
    • Navikas, V.1    Link, J.2    Wahren, B.3    Persson, C.4    Link, H.5
  • 31
    • 0038633458 scopus 로고    scopus 로고
    • TH1 and TH2 cytokine mRNA and protein levels in human immunodeficiency virus (HIV)-seropositive and HIV-seronegative youths
    • Douglas, S. D., Durako, S., Sullivan, K. E., Camarca, M., Moscicki, A. B. and Wilson, C. M., TH1 and TH2 cytokine mRNA and protein levels in human immunodeficiency virus (HIV)-seropositive and HIV-seronegative youths. Clin. Diagn. Lab. Immunol. 2003. 10: 399-404.
    • (2003) Clin. Diagn. Lab. Immunol. , vol.10 , pp. 399-404
    • Douglas, S.D.1    Durako, S.2    Sullivan, K.E.3    Camarca, M.4    Moscicki, A.B.5    Wilson, C.M.6
  • 32
    • 0027340164 scopus 로고
    • ATH1- 4TH2 switch is a critical step in the etiology of HIV infection
    • DOI 10.1016/0167-5699(93)90208-3
    • Clerici, M. and Shearer, G. M., ATH1- 4TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 1993. 14: 107-111. 33 Biasin, M., Boasso, A., Piacentini, L., Trabattoni, D., Magri, G., Deshmuks, R., Deshpande, A. and Clerici, M., IL-4 and CXCR4 upregulation in HIV-infected and uninfected individuals from Maharashtra-Mumbai. Aids 2003. 17: 1563-1565. (Pubitemid 23068292)
    • (1993) Immunology Today , vol.14 , Issue.3 , pp. 107-111
    • Clerici, M.1    Shearer, G.M.2
  • 33
    • 0028609301 scopus 로고
    • The IL4-induced switch of CD8+T cells to a TH2 phenotype and its possible relationship to the onset of AIDS
    • discussion 645-646
    • Erard, F., Dunbar, P. R. and Le Gros, G., The IL4-induced switch of CD8+T cells to a TH2 phenotype and its possible relationship to the onset of AIDS. Res. Immunol. 1994. 145: 643-645; discussion 645-646.
    • (1994) Res. Immunol. , vol.145 , pp. 643-645
    • Erard, F.1    Dunbar, P.R.2    Le Gros, G.3
  • 34
    • 0028848420 scopus 로고
    • Kinetics of cytokine production by thymocytes during murine AIDS caused by LPBM5 retrovirus infection
    • Wang, J., Huang, D. S.,Wood, S., Giger, P. T. andWatson, R. R., Kinetics of cytokine production by thymocytes during murine AIDS caused by LPBM5 retrovirus infection. Immunol. Lett. 1995. 47: 187-192.
    • (1995) Immunol. Lett. , vol.47 , pp. 187-192
    • Wang, J.1    Huang, D.S.2    Wood, S.3    Giger, P.T.4    Watson, R.R.5
  • 35
    • 0035188296 scopus 로고    scopus 로고
    • CD4+Thy1- Thymocytes with a Th-type 2 cytokine response
    • Cerasoli, D. M., Kelsoe, G. and Sarzotti, M., CD4+Thy1- thymocytes with a Th-type 2 cytokine response. Int. Immunol. 2001. 13: 75-83.
    • (2001) Int. Immunol. , vol.13 , pp. 75-83
    • Cerasoli, D.M.1    Kelsoe, G.2    Sarzotti, M.3
  • 36
    • 0036203073 scopus 로고    scopus 로고
    • IL-4 increases Simian immunodeficiency virus replication despite enhanced SIV immune responses in infected rhesus macaques
    • Boyer, J. D., Nath, B., Schumann, K., Curley, E., Manson, K., Kim, J. and Weiner, D. B., IL-4 increases Simian immunodeficiency virus replication despite enhanced SIV immune responses in infected rhesus macaques. Int. J. Parasitol. 2002. 32: 543-550.
    • (2002) Int. J. Parasitol. , vol.32 , pp. 543-550
    • Boyer, J.D.1    Nath, B.2    Schumann, K.3    Curley, E.4    Manson, K.5    Kim, J.6    Weiner, D.B.7
  • 37
    • 0028589592 scopus 로고
    • Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection
    • Carini, C., McLane, M. F., Mayer, K. H. and Essex, M., Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection. Eur. J. Immunol. 1994. 24: 2927-2934.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2927-2934
    • Carini, C.1    McLane, M.F.2    Mayer, K.H.3    Essex, M.4
  • 38
    • 0025350049 scopus 로고
    • Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily
    • DOI 10.1016/0092-8674(90)90342-C
    • Goodwin, R. G., Friend, D., Ziegler, S. F., Jerzy, R., Falk, B. A., Gimpel, S., Cosman, D. et al., Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. Cell 1990. 60: 941-951. (Pubitemid 20103876)
    • (1990) Cell , vol.60 , Issue.6 , pp. 941-951
    • Goodwin, R.G.1    Friend, D.2    Ziegler, S.F.3    Jerzy, R.4    Falk, B.A.5    Gimpel, S.6    Cosman, D.7    Dower, S.K.8    March, C.J.9    Namen, A.E.10    Park, L.S.11
  • 41
    • 77951700631 scopus 로고    scopus 로고
    • Soluble IL-7R alpha (CD127) decreases IL-7 activity on CD8+T-cells and is elevated in HIV infection
    • In press
    • Crawley, A. M. and Angel, J. B., Soluble IL-7R alpha (CD127) decreases IL-7 activity on CD8+T-cells and is elevated in HIV infection. J. Immunol. 2010 In press.
    • (2010) J. Immunol.
    • Crawley, A.M.1    Angel, J.B.2
  • 42
    • 0037023689 scopus 로고    scopus 로고
    • Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain
    • Olosz, F. and Malek, T. R., Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain. J. Biol. Chem. 2002. 277: 12047-12052.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12047-12052
    • Olosz, F.1    Malek, T.R.2
  • 43
    • 0025200120 scopus 로고
    • Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms
    • Varma, C., Chantry, D., Brennan, F., Turner, M., Katz, F. and Feldmann, M., Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms. Cytokine 1990. 2: 55-59.
    • (1990) Cytokine , vol.2 , pp. 55-59
    • Varma, C.1    Chantry, D.2    Brennan, F.3    Turner, M.4    Katz, F.5    Feldmann, M.6
  • 44
    • 58049198420 scopus 로고    scopus 로고
    • IL-2 receptor gamma chain cytokines differentially regulate human CD8+CD127+and CD8+ CD127- T cell division and susceptibility to apoptosis
    • Crawley, A. M., Katz, T., Parato, K. and Angel, J. B., IL-2 receptor gamma chain cytokines differentially regulate human CD8+CD127+and CD8+ CD127- T cell division and susceptibility to apoptosis. Int. Immunol. 2009. 21: 29-42.
    • (2009) Int. Immunol. , vol.21 , pp. 29-42
    • Crawley, A.M.1    Katz, T.2    Parato, K.3    Angel, J.B.4
  • 47
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: Intelligent design
    • Mazzucchelli, R. and Durum, S. K., Interleukin-7 receptor expression: intelligent design. Nat. Rev. Immunol. 2007. 7: 144-154.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 48
    • 0025108018 scopus 로고
    • Inhibitory effect of murine recombinant IL-4 on thymocyte development in fetal thymus organ cultures
    • Plum, J., De Smedt, M., Leclercq, G. and Tison, B., Inhibitory effect of murine recombinant IL-4 on thymocyte development in fetal thymus organ cultures. J. Immunol. 1990. 145: 1066-1073. (Pubitemid 20258706)
    • (1990) Journal of Immunology , vol.145 , Issue.4 , pp. 1066-1073
    • Plum, J.1    De Smedt, M.2    Leclercq, G.3    Tison, B.4
  • 49
    • 0024535021 scopus 로고
    • Selective stimulation of human thymocyte subpopulations by recombinant IL-4 and IL-3
    • DOI 10.1016/0008-8749(89)90386-9
    • Ueno, Y., Boone, T. and Uittenbogaart, C. H., Selective stimulation of human thymocyte subpopulations by recombinant IL-4 and IL-3. Cell Immunol. 1989. 118: 382-393. (Pubitemid 19051458)
    • (1989) Cellular Immunology , vol.118 , Issue.2 , pp. 382-393
    • Ueno, Y.1    Boone, T.2    Uittenbogaart, C.H.3
  • 51
    • 0024462361 scopus 로고
    • IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets
    • Murray, R., Suda, T.,Wrighton, N., Lee, F. and Zlotnik, A., IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets. Int. Immunol. 1989. 1: 526-531.
    • (1989) Int. Immunol. , vol.1 , pp. 526-531
    • Murray, R.1    Suda, T.2    Wrighton, N.3    Lee, F.4    Zlotnik, A.5
  • 52
    • 0025083185 scopus 로고
    • IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice
    • DOI 10.1016/0092-8674(90)90011-3
    • Tepper, R. I., Levinson, D. A., Stanger, B. Z., Campos-Torres, J., Abbas, A. K. and Leder, P., IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice. Cell 1990. 62: 457-467. (Pubitemid 20263216)
    • (1990) Cell , vol.62 , Issue.3 , pp. 457-467
    • Tepper, R.I.1    Levinson, D.A.2    Stanger, B.Z.3    Campos-Torres, J.4    Abbas, A.K.5    Leder, P.6
  • 53
    • 33846861326 scopus 로고    scopus 로고
    • IL-7-induced proliferation of recent thymic emigrants requires activation of the PI3K pathway
    • DOI 10.1182/blood-2006-06-027912
    • Swainson, L., Kinet, S., Mongellaz, C., Sourisseau, M., Henriques, T. and Taylor, N., IL-7-induced proliferation of recent thymic emigrants requires activation of the PI3K pathway. Blood 2007. 109: 1034-1042. (Pubitemid 46220649)
    • (2007) Blood , vol.109 , Issue.3 , pp. 1034-1042
    • Swainson, L.1    Kinet, S.2    Mongellaz, C.3    Sourisseau, M.4    Henriques, T.5    Taylor, N.6
  • 54
    • 0031277415 scopus 로고    scopus 로고
    • IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts
    • Rosenthal, L. A., Winestock, K. D. and Finbloom, D. S., IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts. Cell Immunol. 1997. 181: 172-181.
    • (1997) Cell Immunol. , vol.181 , pp. 172-181
    • Rosenthal, L.A.1    Winestock, K.D.2    Finbloom, D.S.3
  • 55
    • 0036826681 scopus 로고    scopus 로고
    • Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: Resistance to suppression of multiple serine kinase pathways
    • Nagy, Z. S.,Wang, Y., Erwin-Cohen, R. A., Aradi, J., Monia, B.,Wang, L. H., Stepkowski, S. M. et al., Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways. J. Leukoc. Biol. 2002. 72: 819-828.
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 819-828
    • Nagy, Z.S.1    Wang, Y.2    Erwin-Cohen, R.A.3    Aradi, J.4    Monia, B.5    Wang, L.H.6    Stepkowski, S.M.7
  • 56
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • DOI 10.1016/S1074-7613(00)80439-2
    • Kaplan, M. H., Schindler, U., Smiley, S. T. and Grusby, M. J., Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996. 4: 313-319. (Pubitemid 26132509)
    • (1996) Immunity , vol.4 , Issue.3 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 57
    • 0033083261 scopus 로고    scopus 로고
    • IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells
    • Castro, A., Sengupta, T. K., Ruiz, D. C., Yang, E. and Ivashkiv, L. B., IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells. J. Immunol. 1999. 162: 1261-1269. (Pubitemid 29306994)
    • (1999) Journal of Immunology , vol.162 , Issue.3 , pp. 1261-1269
    • Castro, A.1    Sengupta, T.K.2    Ruiz, D.C.3    Yang, E.4    Ivashkiv, L.B.5
  • 58
    • 0032964501 scopus 로고    scopus 로고
    • IL-4 inhibits human CD8 T cell expression of the common IL-2 receptor gamma chain
    • Vyas, B., Vukmanovic-Stejic, M., Noble, A. and Kemeny, D. M., IL-4 inhibits human CD8 T cell expression of the common IL-2 receptor gamma chain. Int. Arch. Allergy Immunol. 1999. 118: 433-436.
    • (1999) Int. Arch. Allergy Immunol. , vol.118 , pp. 433-436
    • Vyas, B.1    Vukmanovic-Stejic, M.2    Noble, A.3    Kemeny, D.M.4
  • 59
    • 0028980744 scopus 로고
    • Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor
    • He, Y. W., Adkins, B., Furse, R. K. and Malek, T. R., Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor. J. Immunol. 1995. 154: 1596-1605.
    • (1995) J. Immunol. , vol.154 , pp. 1596-1605
    • He, Y.W.1    Adkins, B.2    Furse, R.K.3    Malek, T.R.4
  • 60
    • 31344480910 scopus 로고    scopus 로고
    • Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
    • Yu, Q., Park, J. H., Doan, L. L., Erman, B., Feigenbaum, L. and Singer, A., Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection. J. Exp. Med. 2006. 203: 165-175.
    • (2006) J. Exp. Med. , vol.203 , pp. 165-175
    • Yu, Q.1    Park, J.H.2    Doan, L.L.3    Erman, B.4    Feigenbaum, L.5    Singer, A.6
  • 64
    • 0025275713 scopus 로고
    • Growth-promoting activity of IL-1 alpha, IL-6, and tumor necrosis factor-alpha in combination with IL-2, IL-4, or IL-7 on murine thymocytes. Differential effects on CD4/CD8 subsets and on CD3+/CD3- Double-negative thymocytes
    • Suda, T., Murray, R., Guidos, C. and Zlotnik, A., Growth-promoting activity of IL-1 alpha, IL-6, and tumor necrosis factor-alpha in combination with IL-2, IL-4, or IL-7 on murine thymocytes. Differential effects on CD4/CD8 subsets and on CD3+/CD3- double-negative thymocytes. J. Immunol. 1990. 144: 3039-3045.
    • (1990) J. Immunol. , vol.144 , pp. 3039-3045
    • Suda, T.1    Murray, R.2    Guidos, C.3    Zlotnik, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.