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Volumn 115, Issue 17, 2010, Pages 3580-3588

Clonal expansions of cytotoxic T cells exist in the blood of patients with Waldenström macroglobulinemia but exhibit anergic properties and are eliminated by nucleoside analogue therapy

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NUCLEOSIDE ANALOG; T CELL RECEPTOR VBETA; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 77951740292     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-10-246991     Document Type: Article
Times cited : (31)

References (50)
  • 1
    • 0010686026 scopus 로고    scopus 로고
    • Role of interferon-alpha and clonally expanded T cells in the immunotherapy of chronic myelogenous leukemia
    • Fujii S. Role of interferon-alpha and clonally expanded T cells in the immunotherapy of chronic myelogenous leukemia. Leuk Lymphoma. 2000;38(1-2):21-38. (Pubitemid 30224320)
    • (2000) Leukemia and Lymphoma , vol.38 , Issue.1-2 , pp. 21-38
    • Fujii, S.-I.1
  • 2
    • 3242728548 scopus 로고    scopus 로고
    • T cell receptor Vbeta repertoire usage and clonal expansion of T cells in chronic myelogenous leukemia
    • Li YQ, Yang LJ, Chen SH, et al. T cell receptor Vbeta repertoire usage and clonal expansion of T cells in chronic myelogenous leukemia. Chin Med J. 2004;117(6):840-843.
    • (2004) Chin Med J , vol.117 , Issue.6 , pp. 840-843
    • Li, Y.Q.1    Yang, L.J.2    Chen, S.H.3
  • 3
    • 68749108104 scopus 로고    scopus 로고
    • Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
    • Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia. 2009;23(8):1398-1405.
    • (2009) Leukemia , vol.23 , Issue.8 , pp. 1398-1405
    • Mustjoki, S.1    Ekblom, M.2    Arstila, T.P.3
  • 4
    • 33947388858 scopus 로고    scopus 로고
    • Prevalence and clinical association of clonal T cell expansions in myelodysplastic syndrome
    • Epling-Burnette PK, Painter JS, Rollison DE, et al. Prevalence and clinical association of clonal T cell expansions in myelodysplastic syndrome. Leukemia. 2007;21(4):659-667.
    • (2007) Leukemia , vol.21 , Issue.4 , pp. 659-667
    • Epling-Burnette, P.K.1    Painter, J.S.2    Rollison, D.E.3
  • 6
    • 0030923576 scopus 로고    scopus 로고
    • The prognostic significance of T cell receptor beta gene rearrangements and idiotype-reactive T cells in multiple myeloma
    • Brown RD, Yuen E, Nelson M, et al. The prognostic significance of T cell receptor beta gene rearrangements and idiotype-reactive T cells in multiple myeloma. Leukemia. 1997;11(8):1312-1317. (Pubitemid 27387309)
    • (1997) Leukemia , vol.11 , Issue.8 , pp. 1312-1317
    • Brown, R.D.1    Yuen, E.2    Nelson, M.3    Gibson, J.4    Joshua, D.5
  • 8
    • 0035525736 scopus 로고    scopus 로고
    • Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8+CD57+CD28+ compartment
    • Sze DM-Y, Giesajtis G, Brown RD, et al. Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8+CD57+CD28+ compartment. Blood. 2001;98(9):2817-2827.
    • (2001) Blood , vol.98 , Issue.9 , pp. 2817-2827
    • Sze, D.M.-Y.1    Giesajtis, G.2    Brown, R.D.3
  • 10
    • 0141535454 scopus 로고    scopus 로고
    • Clonal cytotoxic T cells in myeloma
    • Sze DM-Y, Brown RD, Yuen E, et al. Clonal cytotoxic T cells in myeloma. Leuk Lymphoma. 2003;44(10):1667-1674.
    • (2003) Leuk Lymphoma , vol.44 , Issue.10 , pp. 1667-1674
    • Sze, D.M.-Y.1    Brown, R.D.2    Yuen, E.3
  • 11
    • 64649097986 scopus 로고    scopus 로고
    • The immunomodulatory action of thalidomide in patients with multiple myeloma involves a clonal expansion of late-differentiated cytotoxic effector cells
    • abstract Abstract 5108
    • Brown RD, Murray A, Sze DM, et al. The immunomodulatory action of thalidomide in patients with multiple myeloma involves a clonal expansion of late-differentiated cytotoxic effector cells [abstract]. Blood. 2005;106(11):359b. Abstract 5108.
    • (2005) Blood , vol.106 , Issue.11
    • Brown, R.D.1    Murray, A.2    Sze, D.M.3
  • 12
    • 0035281541 scopus 로고    scopus 로고
    • Distinct T-cell clonal expansion in the vicinity of tumor cells in plasmacytoma
    • DOI 10.1002/1097-0142(20010301)91:5<900::AID-CNCR1079>3.0.CO;2-Y
    • Lim SH, Badros A, Lue C, et al. Distinct T cell clonal expansion in the vicinity of tumor cells in plasmacytoma. Cancer. 2001;91(5):900-908. (Pubitemid 32198602)
    • (2001) Cancer , vol.91 , Issue.5 , pp. 900-908
    • Strik, H.M.1    Schluesener, H.J.2    Seid, K.3    Meyermann, R.4    Deininger, M.H.5
  • 15
    • 0032970781 scopus 로고    scopus 로고
    • Altered T cell repertoire usage in CD4 and CD8 subsets of multiple myeloma patients, a study of the Eastern Cooperative Oncology Group (E9487)
    • Kay N, Leong T, Kyle RA, et al. Altered T cell repertoire usage in CD4 and CD8 subsets of multiple myeloma patients, a study of the Eastern Cooperative Oncology Group (E9487). Leuk Lymphoma. 1999;33(1-2):127-133. (Pubitemid 29116402)
    • (1999) Leukemia and Lymphoma , vol.33 , Issue.1-2 , pp. 127-133
    • Kay, N.1    Leong, T.2    Kyle, R.A.3    Greipp, P.4    Van Ness, B.5    Bone, N.6    Oken, M.M.7
  • 16
    • 71049147113 scopus 로고    scopus 로고
    • Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma
    • Brown RD, Spencer A, Ho PJ, et al. Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma. Leuk Lymphoma. 2009;50(11):1860-1864.
    • (2009) Leuk Lymphoma , vol.50 , Issue.11 , pp. 1860-1864
    • Brown, R.D.1    Spencer, A.2    Ho, P.J.3
  • 17
    • 58249093949 scopus 로고    scopus 로고
    • Increased incidence of transformation and myelodysplasia/ acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs
    • Leleu X, Soumerai J, Roccaro A, et al. Increased incidence of transformation and myelodysplasia/ acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs. J Clin Oncol. 2009;27(2):250-255.
    • (2009) J Clin Oncol , vol.27 , Issue.2 , pp. 250-255
    • Leleu, X.1    Soumerai, J.2    Roccaro, A.3
  • 18
    • 67649522702 scopus 로고    scopus 로고
    • Balancing risk versus benefit in the treatment of Waldenström's macroglobulinemia patients with nucleoside analogue-based therapy
    • Leleu X, Tamburini J, Roccaoro A, et al. Balancing risk versus benefit in the treatment of Waldenström's macroglobulinemia patients with nucleoside analogue-based therapy. Clin Lymphoma Myeloma. 2009;9(1):71-73.
    • (2009) Clin Lymphoma Myeloma , vol.9 , Issue.1 , pp. 71-73
    • Leleu, X.1    Tamburini, J.2    Roccaoro, A.3
  • 19
    • 11244307997 scopus 로고    scopus 로고
    • Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: Diagnostic and prognostic implications
    • DOI 10.1182/blood-2004-06-2220
    • Assaf C, Hummel M, Steinhoff M, et al. Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications. Blood. 2005;105(2):503-510. (Pubitemid 40070728)
    • (2005) Blood , vol.105 , Issue.2 , pp. 503-510
    • Assaf, C.1    Hummel, M.2    Steinhoff, M.3    Geilen, C.C.4    Orawa, H.5    Stein, H.6    Orfanos, C.E.7
  • 20
    • 0027205203 scopus 로고
    • Human T cells respond to mouse mammary tumor virus-encoded superantigen: Vbeta restriction and conserved evolutionary features
    • Labrecque N, McGrath HSubramanyam M, et al. Human T cells respond to mouse mammary tumor virus-encoded superantigen: V beta restriction and conserved evolutionary features. J Exp Med. 1993;177(6):1735-1743. (Pubitemid 23146140)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.6 , pp. 1735-1743
    • Labrecque, N.1    McGrath, H.2    Subramanyam, M.3    Huber, B.T.4    Sekaly, R.-P.5
  • 21
    • 0024346908 scopus 로고
    • Interaction of Staphylococcus aureus toxin "superantigens" with human T cells
    • Choi YW, Kotzin B, Herron L, et al. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989;86(22):8941-8945.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , Issue.22 , pp. 8941-8945
    • Choi, Y.W.1    Kotzin, B.2    Herron, L.3
  • 22
    • 9644277298 scopus 로고    scopus 로고
    • IMGT/JunctionAnalysis: The first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONs
    • DOI 10.1093/bioinformatics/bth945
    • Yousfi Monod M, Giudicelli V, Chaume D, et al. IMGT/JunctionAnalysis: the first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONs. Bioinformatics. 2004;20(suppl 1):i379-i385. (Pubitemid 41296713)
    • (2004) Bioinformatics , vol.20 , Issue.SUPPL. 1
    • Monod, M.Y.1    Giudicelli, V.2    Chaume, D.3    Lefranc, M.-P.4
  • 23
    • 1342288026 scopus 로고    scopus 로고
    • Affy - Analysis of Affymetrix GeneChip data at the probe level
    • DOI 10.1093/bioinformatics/btg405
    • Gautier L, Cope L, Bolstad BM, et al. Affy: analysis of Affymetrix GeneChip data at the probe level. Bioinformatics. 2004;20(3):307-315. (Pubitemid 38262761)
    • (2004) Bioinformatics , vol.20 , Issue.3 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 24
    • 0030305457 scopus 로고    scopus 로고
    • R: A language for data analysis and graphics
    • Ihaka R, Gentleman R. R: a language for data analysis and graphics. J Comput Graph Stat. 1996;5(3):299-314.
    • (1996) J Comput Graph Stat , vol.5 , Issue.3 , pp. 299-314
    • Ihaka, R.1    Gentleman, R.2
  • 25
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DJ, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80.1-R80.16.
    • (2004) Genome Biol , vol.5 , Issue.10
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.J.3
  • 28
    • 84870532154 scopus 로고    scopus 로고
    • Accessed May 12, 2009
    • National Center for Biotechnology Information. Gene Expression Omnibus (GEO). http://www.ncbi.nlm.nih.gov/geo. Accessed May 12, 2009.
    • Gene Expression Omnibus (GEO)
  • 29
    • 61849130012 scopus 로고    scopus 로고
    • Microarray analysis reveals similarity between CD8+CD28- T cells from young and elderly persons, but not of CD8+CD28+ T cells
    • Lazuardi L, Herndler-Brandstetter D, Brunner S, et al. Microarray analysis reveals similarity between CD8+CD28- T cells from young and elderly persons, but not of CD8+CD28+ T cells. Biogerontology. 2009;10(2):191-202.
    • (2009) Biogerontology , vol.10 , Issue.2 , pp. 191-202
    • Lazuardi, L.1    Herndler-Brandstetter, D.2    Brunner, S.3
  • 32
    • 50949127683 scopus 로고    scopus 로고
    • Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: Perforin and granzyme B)
    • Araki Y, Fann M, Wersto R, et al. Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). J Immunol. 2008;180(12):8102-8108.
    • (2008) J Immunol , vol.180 , Issue.12 , pp. 8102-8108
    • Araki, Y.1    Fann, M.2    Wersto, R.3
  • 34
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article 3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article 3.
    • (2004) Stat Appl Genet Mol Biol , pp. 3
    • Smyth, G.K.1
  • 35
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A. 2003;100(16):9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.16 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 36
    • 33748668261 scopus 로고    scopus 로고
    • Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line
    • Fiebig AA, Zhu W, Hollerbach C, et al. Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line. BMC Cancer. 2006;6:213-227.
    • (2006) BMC Cancer , vol.6 , pp. 213-227
    • Fiebig, A.A.1    Zhu, W.2    Hollerbach, C.3
  • 37
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
    • DOI 10.1038/43474
    • Romashkova JA, Makarov SS. NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature. 1999;401(6748):86-90. (Pubitemid 29418448)
    • (1999) Nature , vol.401 , Issue.6748 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 38
    • 2342641439 scopus 로고    scopus 로고
    • Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway
    • DOI 10.1038/sj.onc.1207485
    • Makino K, Day CP, Wang SC, et al. Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway. Oncogene. 2004;23(21):3883-3887. (Pubitemid 38725701)
    • (2004) Oncogene , vol.23 , Issue.21 , pp. 3883-3887
    • Makino, K.1    Day, C.-P.2    Wang, S.-C.3    Li, Y.M.4    Hung, M.-C.5
  • 40
    • 0034703099 scopus 로고    scopus 로고
    • Transmembrane phosphoprotein Cbp positively regulates the activity of the carboxyl-terminal Src kinase, Csk
    • DOI 10.1074/jbc.C000326200
    • Takeuchi S, Takayama Y, Ogawa A, et al. Transmembrane phosphoprotein Cbp positively regulates the activity of the carboxyl-terminal Src kinase, Csk. J Biol Chem. 2000;275(38):29183-29186. (Pubitemid 32043785)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.38 , pp. 29183-29186
    • Takeuchi, S.1    Takayama, Y.2    Ogawa, A.3    Tamura, K.4    Okada, M.5
  • 42
    • 65949115703 scopus 로고    scopus 로고
    • Tob, a member of the APRO family, regulates immunological quiescence and tumor suppression
    • Tzachanis D, Boussiotis VA. Tob, a member of the APRO family, regulates immunological quiescence and tumor suppression. Cell Cycle. 2009;8(7):1019-1025.
    • (2009) Cell Cycle , vol.8 , Issue.7 , pp. 1019-1025
    • Tzachanis, D.1    Boussiotis, V.A.2
  • 44
    • 0030996527 scopus 로고    scopus 로고
    • Activin a induction of cell-cycle arrest involves modulation of cyclin D2 and(CIP1/WAF1) in plasmacytic cells
    • DOI 10.1210/me.11.8.1044
    • Yamato K, Koseki T, Ohguchi M, et al. Activin A induction of cell-cycle arrest involves modulation of Cyclin D2 and p21CIP1/WAF1 in plasmacytic cells. Mol Endocrinol. 1997;11(8):1044-1052. (Pubitemid 27278827)
    • (1997) Molecular Endocrinology , vol.11 , Issue.8 , pp. 1044-1052
    • Yamato, K.1    Koseki, T.2    Ohguchi, M.3    Kizaki, M.4    Ikeda, Y.5    Nishihara, T.6
  • 45
    • 0032996623 scopus 로고    scopus 로고
    • c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points
    • Mateyak MK, Obaya AJ, Sedivy JM. c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points. Mol Cell Biol. 1999;19(7):4672-4683.
    • (1999) Mol Cell Biol , vol.19 , Issue.7 , pp. 4672-4683
    • Mateyak, M.K.1    Obaya, A.J.2    Sedivy, J.M.3
  • 46
    • 33747872306 scopus 로고    scopus 로고
    • A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclindependent kinase 4/6
    • Baughn LB, Liberto MD, Wu KD, et al. A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclindependent kinase 4/6. Cancer Res. 2006;66(15):7661-7667.
    • (2006) Cancer Res , vol.66 , Issue.15 , pp. 7661-7667
    • Baughn, L.B.1    Liberto, M.D.2    Wu, K.D.3
  • 47
    • 1642414254 scopus 로고    scopus 로고
    • Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: Dynamics and subcellular location
    • DOI 10.1042/BJ20031244
    • Nika K, Hyunh H, Williams S, et al. Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location. Biochem J. 2004;378(pt 2):335-342. (Pubitemid 38367224)
    • (2004) Biochemical Journal , vol.378 , Issue.2 , pp. 335-342
    • Nika, K.1    Hyunh, H.2    Williams, S.3    Paul, S.4    Bottini, N.5    Tasken, K.6    Lombroso, P.J.7    Mustelin, T.8
  • 48
    • 0032546961 scopus 로고    scopus 로고
    • Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP)
    • DOI 10.1074/jbc.273.25.15340
    • Saxena M, Williams S, Gilman J, et al. Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP). J Biol Chem. 1998;273(25):15340-15344. (Pubitemid 28298136)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.25 , pp. 15340-15344
    • Saxena, M.1    Williams, S.2    Gilman, J.3    Mustelin, T.4
  • 49
    • 0033598783 scopus 로고    scopus 로고
    • c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation
    • Cong F, Goff SP. c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation. Proc Natl Acad Sci U S A. 1999;96(24):13819-13824.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.24 , pp. 13819-13824
    • Cong, F.1    Goff, S.P.2


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