Overexpressing cellular repressor of E1A-stimulated genes protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt

Apoptosis

Volumn 15, Issue 4, 2010, Pages 463-473

  Deng, Jie ^a,b   Han, Yaling ^b   Yan, Chenhui ^b   Tian, Xiaoxiang ^b   Tao, Jie ^b   Kang, Jian ^b   Li, Shaohua ^c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b SHENYANG NORTHERN HOSPITAL   (China)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Akt; Apoptosis; Cellular repressor of E1A stimulated genes; Mesenchymal stem cells; P53

Indexed keywords

CASPASE 3; E1A PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; REPRESSOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; CELL CYCLE ARREST; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSFORMATION; MALE; MEMBRANE PERMEABILITY; MESENCHYMAL STEM CELL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL HYPOXIA; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYTOPROTECTION; DOWN-REGULATION; ENZYME ACTIVATION; MALE; MESENCHYMAL STEM CELLS; MITOCHONDRIA; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 77951665628     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0434-7     Document Type: Article

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