메뉴 건너뛰기




Volumn 38, Issue 5, 2009, Pages 1559-1574

Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA PRECURSOR; T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 77951658657     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1115     Document Type: Article
Times cited : (9)

References (63)
  • 2
    • 34247197937 scopus 로고    scopus 로고
    • The nonsense-mediated decay RNA surveillance pathway
    • Chang, Y.F., Imam, J.S. and Wilkinson, M.F. (2007) The nonsense-mediated decay RNA surveillance pathway. Annu. Rev. Biochem., 76, 51-74.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 51-74
    • Chang, Y.F.1    Imam, J.S.2    Wilkinson, M.F.3
  • 3
    • 49949105213 scopus 로고    scopus 로고
    • The multiple lives of NMD factors: balancing roles in gene and genome regulation
    • Isken, O. and Maquat, L.E. (2008) The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat. Rev. Genet., 9, 699-712.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 699-712
    • Isken, O.1    Maquat, L.E.2
  • 6
    • 0028884942 scopus 로고
    • A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro
    • Carter, M.S., Doskow, J., Morris, P., Li, S., Nhim, R.P., Sandstedt, S. and Wilkinson, M.F. (1995) A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro. J. Biol. Chem., 270, 28995-29003.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28995-29003
    • Carter, M.S.1    Doskow, J.2    Morris, P.3    Li, S.4    Nhim, R.P.5    Sandstedt, S.6    Wilkinson, M.F.7
  • 7
    • 0032006979 scopus 로고    scopus 로고
    • Nonsense surveillance in lymphocytes?
    • Li, S. and Wilkinson, M.F. (1998) Nonsense surveillance in lymphocytes? Immunity, 8, 135-141.
    • (1998) Immunity , vol.8 , pp. 135-141
    • Li, S.1    Wilkinson, M.F.2
  • 8
    • 0037080771 scopus 로고    scopus 로고
    • T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts
    • Gudikote, J.P. and Wilkinson, M.F. (2002) T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts. EMBO J., 21, 125-134.
    • (2002) EMBO J , vol.21 , pp. 125-134
    • Gudikote, J.P.1    Wilkinson, M.F.2
  • 9
    • 0037166282 scopus 로고    scopus 로고
    • A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation
    • Wang, J., Vock, V.M., Li, S., Olivas, O.R. and Wilkinson, M.F. (2002) A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation. J. Biol. Chem., 277, 18489-18493.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18489-18493
    • Wang, J.1    Vock, V.M.2    Li, S.3    Olivas, O.R.4    Wilkinson, M.F.5
  • 13
    • 0037064145 scopus 로고    scopus 로고
    • Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts
    • Mendell, J.T., ap Rhys, C.M. and Dietz, H.C. (2002) Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science, 298, 419-422.
    • (2002) Science , vol.298 , pp. 419-422
    • Mendell, J.T.1    ap Rhys, C.M.2    Dietz, H.C.3
  • 14
    • 0036809882 scopus 로고    scopus 로고
    • Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay
    • Wang, J., Chang, Y.F., Hamilton, J.I. and Wilkinson, M.F. (2002) Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay. Mol. Cell, 10, 951-957.
    • (2002) Mol. Cell , vol.10 , pp. 951-957
    • Wang, J.1    Chang, Y.F.2    Hamilton, J.I.3    Wilkinson, M.F.4
  • 15
    • 0037025175 scopus 로고    scopus 로고
    • Alternatively spliced TCR mRNA induced by disruption of reading frame
    • Wang, J., Hamilton, J.I., Carter, M.S., Li, S. and Wilkinson, M.F. (2002) Alternatively spliced TCR mRNA induced by disruption of reading frame. Science, 297, 108-110.
    • (2002) Science , vol.297 , pp. 108-110
    • Wang, J.1    Hamilton, J.I.2    Carter, M.S.3    Li, S.4    Wilkinson, M.F.5
  • 16
    • 35648958676 scopus 로고    scopus 로고
    • Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame
    • Chang, Y.F., Chan, W.K., Imam, J.S. and Wilkinson, M.F. (2007) Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. J. Biol. Chem., 282, 29738-29747.
    • (2007) J. Biol. Chem. , vol.282 , pp. 29738-29747
    • Chang, Y.F.1    Chan, W.K.2    Imam, J.S.3    Wilkinson, M.F.4
  • 17
    • 0037099302 scopus 로고    scopus 로고
    • A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer
    • Caputi, M., Kendzior, R.J. Jr and Beemon, K.L. (2002) A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer. Genes Dev., 16, 1754-1759.
    • (2002) Genes Dev. , vol.16 , pp. 1754-1759
    • Caputi, M.1    Kendzior R.J., Jr.2    Beemon, K.L.3
  • 18
    • 0028136599 scopus 로고
    • Maintenance of an open reading frame as an additional level of scrutiny during splice site selection
    • Dietz, H.C. and Kendzior, R.J. Jr (1994) Maintenance of an open reading frame as an additional level of scrutiny during splice site selection. Nat. Genet., 8, 183-188.
    • (1994) Nat. Genet. , vol.8 , pp. 183-188
    • Dietz, H.C.1    Kendzior R.J. Jr2
  • 19
    • 0033529631 scopus 로고    scopus 로고
    • A premature termination codon in either exon of minute virus of mice P4 promoter-generated pre-mRNA can inhibit nuclear splicing of the intervening intron in an open reading frame-dependent manner
    • Gersappe, A., Burger, L. and Pintel, D.J. (1999) A premature termination codon in either exon of minute virus of mice P4 promoter-generated pre-mRNA can inhibit nuclear splicing of the intervening intron in an open reading frame-dependent manner. J. Biol. Chem., 274, 22452-22458.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22452-22458
    • Gersappe, A.1    Burger, L.2    Pintel, D.J.3
  • 20
    • 0033019838 scopus 로고    scopus 로고
    • A premature termination codon interferes with the nuclear function of an exon splicing enhancer in an open reading frame-dependent manner
    • Gersappe, A. and Pintel, D.J. (1999) A premature termination codon interferes with the nuclear function of an exon splicing enhancer in an open reading frame-dependent manner. Mol. Cell. Biol., 19, 1640-1650.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1640-1650
    • Gersappe, A.1    Pintel, D.J.2
  • 21
    • 0035158730 scopus 로고    scopus 로고
    • A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes
    • Liu, H.X., Cartegni, L., Zhang, M.Q. and Krainer, A.R. (2001) A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes. Nat. Genet., 27, 55-58.
    • (2001) Nat. Genet. , vol.27 , pp. 55-58
    • Liu, H.X.1    Cartegni, L.2    Zhang, M.Q.3    Krainer, A.R.4
  • 22
    • 0037099212 scopus 로고    scopus 로고
    • NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on
    • Maquat, L.E. (2002) NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on. Genes Dev., 16, 1743-1753.
    • (2002) Genes Dev , vol.16 , pp. 1743-1753
    • Maquat, L.E.1
  • 24
    • 1642528941 scopus 로고    scopus 로고
    • Premature termination codons do not affect the rate of splicing of neighboring introns
    • Lytle, J.R. and Steitz, J.A. (2004) Premature termination codons do not affect the rate of splicing of neighboring introns. RNA, 10, 657-668.
    • (2004) RNA , vol.10 , pp. 657-668
    • Lytle, J.R.1    Steitz, J.A.2
  • 25
    • 15844406352 scopus 로고    scopus 로고
    • Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis
    • Aoufouchi, S., Yelamos, J. and Milstein, C. (1996) Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell, 85, 415-422.
    • (1996) Cell , vol.85 , pp. 415-422
    • Aoufouchi, S.1    Yelamos, J.2    Milstein, C.3
  • 26
    • 0028147091 scopus 로고
    • Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing
    • Lozano, F., Maertzdorf, B., Pannell, R. and Milstein, C. (1994) Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. EMBO J., 13, 4617-4622.
    • (1994) EMBO J , vol.13 , pp. 4617-4622
    • Lozano, F.1    Maertzdorf, B.2    Pannell, R.3    Milstein, C.4
  • 27
    • 0026694808 scopus 로고
    • Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product
    • Naeger, L.K., Schoborg, R.V., Zhao, Q., Tullis, G.E. and Pintel, D.J. (1992) Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product. Genes Dev., 6, 1107-1119.
    • (1992) Genes Dev. , vol.6 , pp. 1107-1119
    • Naeger, L.K.1    Schoborg, R.V.2    Zhao, Q.3    Tullis, G.E.4    Pintel, D.J.5
  • 28
    • 0036205348 scopus 로고    scopus 로고
    • Boundary-independent polar nonsense-mediated decay
    • Wang, J., Gudikote, J.P., Olivas, O.R. and Wilkinson, M.F. (2002) Boundary-independent polar nonsense-mediated decay. EMBO Rep., 3, 274-279.
    • (2002) EMBO Rep. , vol.3 , pp. 274-279
    • Wang, J.1    Gudikote, J.P.2    Olivas, O.R.3    Wilkinson, M.F.4
  • 29
    • 0036245628 scopus 로고    scopus 로고
    • 0 overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi, M. and Taira, K. (2002) U6 promoter-driven siRNAs with four uridine 30 overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol., 20, 497-500.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 30
    • 0027410487 scopus 로고
    • T cell receptor-beta mRNA splicing: regulation of unusual splicing intermediates
    • Qian, L., Theodor, L., Carter, M., Vu, M.N., Sasaki, A.W. and Wilkinson, M.F. (1993) T cell receptor-beta mRNA splicing: regulation of unusual splicing intermediates. Mol. Cell. Biol., 13, 1686-1696.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1686-1696
    • Qian, L.1    Theodor, L.2    Carter, M.3    Vu, M.N.4    Sasaki, A.W.5    Wilkinson, M.F.6
  • 31
    • 0027536976 scopus 로고
    • Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA
    • Cheng, J. and Maquat, L.E. (1993) Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Mol. Cell. Biol., 13, 1892-1902.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1892-1902
    • Cheng, J.1    Maquat, L.E.2
  • 32
    • 0029908912 scopus 로고    scopus 로고
    • A splicing-dependent regulatory mechanism that detects translation signals
    • Carter, M.S., Li, S. and Wilkinson, M.F. (1996) A splicing-dependent regulatory mechanism that detects translation signals. EMBO J., 15, 5965-5975.
    • (1996) EMBO J , vol.15 , pp. 5965-5975
    • Carter, M.S.1    Li, S.2    Wilkinson, M.F.3
  • 33
    • 0029330286 scopus 로고
    • When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells
    • Maquat, L.E. (1995) When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. RNA, 1, 453-465.
    • (1995) RNA , vol.1 , pp. 453-465
    • Maquat, L.E.1
  • 34
    • 0031004756 scopus 로고    scopus 로고
    • T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: a nuclear-associated translation-like mechanism
    • Li, S., Leonard, D. and Wilkinson, M.F. (1997) T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: a nuclear-associated translation-like mechanism. J. Exp. Med., 185, 985-992.
    • (1997) J. Exp. Med. , vol.185 , pp. 985-992
    • Li, S.1    Leonard, D.2    Wilkinson, M.F.3
  • 35
    • 7044227587 scopus 로고    scopus 로고
    • Stop codon-mediated suppression of splicing is a novel nuclear scanning mechanism not affected by elements of protein synthesis and NMD
    • Wachtel, C., Li, B., Sperling, J. and Sperling, R. (2004) Stop codon-mediated suppression of splicing is a novel nuclear scanning mechanism not affected by elements of protein synthesis and NMD. RNA, 10, 1740-1750.
    • (2004) RNA , vol.10 , pp. 1740-1750
    • Wachtel, C.1    Li, B.2    Sperling, J.3    Sperling, R.4
  • 36
    • 1842635464 scopus 로고    scopus 로고
    • Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression
    • Zheng, Z.M. (2004) Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. J. Biomed. Sci., 11, 278-294.
    • (2004) J. Biomed. Sci. , vol.11 , pp. 278-294
    • Zheng, Z.M.1
  • 37
    • 0034161419 scopus 로고    scopus 로고
    • Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases
    • Blencowe, B.J. (2000) Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases. Trends Biochem. Sci., 25, 106-110.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 106-110
    • Blencowe, B.J.1
  • 38
    • 60849108914 scopus 로고    scopus 로고
    • Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing
    • Zhang, X.H., Arias, M.A., Ke, S. and Chasin, L.A. (2009) Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing. RNA, 15, 367-376.
    • (2009) RNA , vol.15 , pp. 367-376
    • Zhang, X.H.1    Arias, M.A.2    Ke, S.3    Chasin, L.A.4
  • 39
    • 0042242582 scopus 로고    scopus 로고
    • ESEfinder: A web resource to identify exonic splicing enhancers
    • Cartegni, L., Wang, J., Zhu, Z., Zhang, M.Q. and Krainer, A.R. (2003) ESEfinder: A web resource to identify exonic splicing enhancers. Nucleic Acids Res., 31, 3568-3571.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3568-3571
    • Cartegni, L.1    Wang, J.2    Zhu, Z.3    Zhang, M.Q.4    Krainer, A.R.5
  • 40
    • 0037047644 scopus 로고    scopus 로고
    • Predictive identification of exonic splicing enhancers in human genes
    • Fairbrother, W.G., Yeh, R.F., Sharp, P.A. and Burge, C.B. (2002) Predictive identification of exonic splicing enhancers in human genes. Science, 297, 1007-1013.
    • (2002) Science , vol.297 , pp. 1007-1013
    • Fairbrother, W.G.1    Yeh, R.F.2    Sharp, P.A.3    Burge, C.B.4
  • 41
    • 0026607344 scopus 로고
    • Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene
    • Steingrimsdottir, H., Rowley, G., Dorado, G., Cole, J. and Lehmann, A.R. (1992) Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene. Nucleic Acids Res., 20, 1201-1208.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1201-1208
    • Steingrimsdottir, H.1    Rowley, G.2    Dorado, G.3    Cole, J.4    Lehmann, A.R.5
  • 42
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore, C., Lee, V.M. and Trojanowski, J.Q. (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci., 8, 663-672.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 43
    • 0027507225 scopus 로고
    • Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene
    • Chen, I.T. and Chasin, L.A. (1993) Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol. Cell. Biol., 13, 289-300.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 289-300
    • Chen, I.T.1    Chasin, L.A.2
  • 44
    • 18144386947 scopus 로고    scopus 로고
    • Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution
    • Pagani, F., Raponi, M. and Baralle, F.E. (2005) Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution. Proc. Natl Acad. Sci. USA, 102, 6368-6372.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 6368-6372
    • Pagani, F.1    Raponi, M.2    Baralle, F.E.3
  • 45
    • 0346786528 scopus 로고    scopus 로고
    • Cytoplasmic degradation of splice-defective pre-mRNAs and intermediates
    • Hilleren, P.J. and Parker, R. (2003) Cytoplasmic degradation of splice-defective pre-mRNAs and intermediates. Mol. Cell, 12, 1453-1465.
    • (2003) Mol. Cell , vol.12 , pp. 1453-1465
    • Hilleren, P.J.1    Parker, R.2
  • 46
    • 0034664803 scopus 로고    scopus 로고
    • Identification of a regulated pathway for nuclear pre-mRNA turnover
    • Bousquet-Antonelli, C., Presutti, C. and Tollervey, D. (2000) Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell, 102, 765-775.
    • (2000) Cell , vol.102 , pp. 765-775
    • Bousquet-Antonelli, C.1    Presutti, C.2    Tollervey, D.3
  • 47
    • 0037154964 scopus 로고    scopus 로고
    • A conserved mRNA export machinery coupled to pre-mRNA splicing
    • Reed, R. and Hurt, E. (2002) A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell, 108, 523-531.
    • (2002) Cell , vol.108 , pp. 523-531
    • Reed, R.1    Hurt, E.2
  • 48
    • 33746611927 scopus 로고    scopus 로고
    • Mutant LYS2 mRNAs retained and degraded in the nucleus of Saccharomyces cerevisiae
    • Das, B., Das, S. and Sherman, F. (2006) Mutant LYS2 mRNAs retained and degraded in the nucleus of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 103, 10871-10876.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 10871-10876
    • Das, B.1    Das, S.2    Sherman, F.3
  • 49
    • 0035983990 scopus 로고    scopus 로고
    • Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs
    • Torchet, C., Bousquet-Antonelli, C., Milligan, L., Thompson, E., Kufel, J. and Tollervey, D. (2002) Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs. Mol. Cell, 9, 1285-1296.
    • (2002) Mol. Cell , vol.9 , pp. 1285-1296
    • Torchet, C.1    Bousquet-Antonelli, C.2    Milligan, L.3    Thompson, E.4    Kufel, J.5    Tollervey, D.6
  • 50
    • 0038054468 scopus 로고    scopus 로고
    • RNAse III-mediated degradation of unspliced pre-mRNAs and lariat introns
    • Danin-Kreiselman, M., Lee, C.Y. and Chanfreau, G. (2003) RNAse III-mediated degradation of unspliced pre-mRNAs and lariat introns. Mol. Cell, 11, 1279-1289.
    • (2003) Mol. Cell , vol.11 , pp. 1279-1289
    • Danin-Kreiselman, M.1    Lee, C.Y.2    Chanfreau, G.3
  • 51
    • 0742304306 scopus 로고    scopus 로고
    • Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1
    • Galy, V., Gadal, O., Fromont-Racine, M., Romano, A., Jacquier, A. and Nehrbass, U. (2004) Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1. Cell, 116, 63-73.
    • (2004) Cell , vol.116 , pp. 63-73
    • Galy, V.1    Gadal, O.2    Fromont-Racine, M.3    Romano, A.4    Jacquier, A.5    Nehrbass, U.6
  • 52
    • 33745608077 scopus 로고    scopus 로고
    • A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention
    • Scherrer, F.W. Jr and Spingola, M. (2006) A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention. RNA, 12, 1361-1372.
    • (2006) RNA , vol.12 , pp. 1361-1372
    • Scherrer F.W., Jr.1    Spingola, M.2
  • 53
    • 57749097695 scopus 로고    scopus 로고
    • An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex
    • Trowitzsch, S., Weber, G., Luhrmann, R. and Wahl, M.C. (2008) An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. J. Biol. Chem., 283, 32317-32327.
    • (2008) J. Biol. Chem. , vol.283 , pp. 32317-32327
    • Trowitzsch, S.1    Weber, G.2    Luhrmann, R.3    Wahl, M.C.4
  • 54
    • 0036784630 scopus 로고    scopus 로고
    • In vivo kinetics of mRNA splicing and transport in mammalian cells
    • Audibert, A., Weil, D. and Dautry, F. (2002) In vivo kinetics of mRNA splicing and transport in mammalian cells. Mol. Cell. Biol., 22, 6706-6718.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6706-6718
    • Audibert, A.1    Weil, D.2    Dautry, F.3
  • 55
    • 70350754211 scopus 로고    scopus 로고
    • Rates of in situ transcription and splicing in large human genes
    • Singh, J. and Padgett, R.A. (2009) Rates of in situ transcription and splicing in large human genes. Nat. Struct. Mol. Biol., 11, 1123-1124.
    • (2009) Nat. Struct. Mol. Biol. , vol.11 , pp. 1123-1124
    • Singh, J.1    Padgett, R.A.2
  • 56
    • 0027495952 scopus 로고
    • Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA
    • Kessler, O., Jiang, Y. and Chasin, L.A. (1993) Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA. Mol. Cell. Biol., 13, 6211-6222.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6211-6222
    • Kessler, O.1    Jiang, Y.2    Chasin, L.A.3
  • 57
    • 0027330895 scopus 로고
    • T cell receptor-beta mRNA splicing during thymic maturation in vivo and in an inducible T cell clone in vitro
    • Qian, L., Vu, M.N., Carter, M.S., Doskow, J. and Wilkinson, M.F. (1993) T cell receptor-beta mRNA splicing during thymic maturation in vivo and in an inducible T cell clone in vitro. J. Immunol., 151, 6801-6814.
    • (1993) J. Immunol. , vol.151 , pp. 6801-6814
    • Qian, L.1    Vu, M.N.2    Carter, M.S.3    Doskow, J.4    Wilkinson, M.F.5
  • 58
    • 0028895417 scopus 로고
    • Exon recognition in vertebrate splicing
    • Berget, S.M. (1995) Exon recognition in vertebrate splicing. J. Biol. Chem., 270, 2411-2414.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2411-2414
    • Berget, S.M.1
  • 59
    • 35348897138 scopus 로고    scopus 로고
    • Role of purine-rich exonic splicing enhancers in nuclear retention of pre-mRNAs
    • Taniguchi, I., Masuyama, K. and Ohno, M. (2007) Role of purine-rich exonic splicing enhancers in nuclear retention of pre-mRNAs. Proc. Natl Acad. Sci. USA, 104, 13684-13689.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 13684-13689
    • Taniguchi, I.1    Masuyama, K.2    Ohno, M.3
  • 60
    • 0028025033 scopus 로고
    • A splicing enhancer exhibits both constitutive and regulated activities
    • Tian, M. and Maniatis, T. (1994) A splicing enhancer exhibits both constitutive and regulated activities. Genes Dev., 8, 1703-1712.
    • (1994) Genes Dev. , vol.8 , pp. 1703-1712
    • Tian, M.1    Maniatis, T.2
  • 61
    • 0037275978 scopus 로고    scopus 로고
    • Nuclear translation: what is the evidence?
    • Dahlberg, J.E., Lund, E. and Goodwin, E.B. (2003) Nuclear translation: what is the evidence? RNA, 9, 1-8.
    • (2003) RNA , vol.9 , pp. 1-8
    • Dahlberg, J.E.1    Lund, E.2    Goodwin, E.B.3
  • 62
    • 0036300610 scopus 로고    scopus 로고
    • RNA surveillance by nuclear scanning?
    • Wilkinson, M.F. and Shyu, A.B. (2002) RNA surveillance by nuclear scanning? Nat. Cell. Biol., 4, E144-E147.
    • (2002) Nat. Cell. Biol. , vol.4
    • Wilkinson, M.F.1    Shyu, A.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.