The Human Breast Cancer Resistance Protein (BCRP/ABCG2) Shows Conformational Changes with Mitoxantrone

Structure

Volumn 18, Issue 4, 2010, Pages 482-493

  Rosenberg, Mark F ^a   Bikadi, Zsolt ^b,c   Chan, Janice ^a   Liu, Xiaoping ^b   Ni, Zhanglin ^b   Cai, Xiaokun ^b   Ford, Robert C ^a   Mao, Qingcheng ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Virtua Drug Ltd   (Hungary)

Author keywords

Humdisease; Proteins

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MITOXANTRONE; NUCLEOTIDE;

ALPHA HELIX; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTALLIZATION; DRUG PROTEIN BINDING; ENZYME SUBSTRATE COMPLEX; MOLECULAR MODEL; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELL MEMBRANE; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HUMANS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MITOXANTRONE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NEOPLASM PROTEINS; PICHIA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY;

PICHIA PASTORIS;

EID: 77951651875     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2010.01.017     Document Type: Article

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