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Volumn 7, Issue 1, 2010, Pages 29-38

2D DIGE of the cerebrospinal fluid proteome in neurological diseases

Author keywords

2D DIGE; Biomarker; Cerebrospinal fluid; Neurological disease; Proteome

Indexed keywords

ACTIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; ANGIOTENSINOGEN; APOLIPOPROTEIN A4; APOLIPOPROTEIN E; ARYLDIALKYLPHOSPHATASE 1; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CATHEPSIN D; CERULOPLASMIN; CHROMOGRANIN B; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; CYSTATIN C; FIBRINOGEN; GELSOLIN; HAPTOGLOBIN; IMMUNOGLOBULIN HEAVY CHAIN; INITIATION FACTOR 4G; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEURON SPECIFIC ENOLASE; OSTEOPONTIN; PREALBUMIN; PROCOLLAGEN; PROSTAGLANDIN D SYNTHASE; PROTEIN 14 3 3; PROTEINASE; TRANSFERRIN; VITAMIN D BINDING PROTEIN;

EID: 77951643449     PISSN: 14789450     EISSN: 17448387     Source Type: Journal    
DOI: 10.1586/epr.09.99     Document Type: Review
Times cited : (25)

References (52)
  • 1
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred defnitions and conceptual framework
    • Biomarkers and surrogate endpoints: preferred defnitions and conceptual framework. Clin. Pharmacol. Ther. 69(3), 89-95 (2001).
    • (2001) Clin. Pharmacol. Ther. , vol.69 , Issue.3 , pp. 89-95
  • 2
    • 3142556134 scopus 로고    scopus 로고
    • Development of biomarkers in multiple sclerosis
    • Bielekova B, Martin R. Development of biomarkers in multiple sclerosis. Brain 127(Pt 7), 1463-1478 (2004).
    • (2004) Brain , vol.127 , Issue.PART 7 , pp. 1463-1478
    • Bielekova, B.1    Martin, R.2
  • 3
    • 0024520844 scopus 로고
    • Surrogate endpoints in clinical trials: Defnition and operational criteria
    • Prentice RL. Surrogate endpoints in clinical trials: defnition and operational criteria. Stat. Med. 8(4), 431-440 (1989).
    • (1989) Stat. Med. , vol.8 , Issue.4 , pp. 431-440
    • Prentice, R.L.1
  • 5
    • 42749100518 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for Alzheimer's disease
    • Birks J. Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst. Rev. (1), CD005593 (2006).
    • (2006) Cochrane Database Syst. Rev. , vol.1
    • Birks, J.1
  • 7
    • 0028269876 scopus 로고
    • Flow rate of cerebrospinal fuid (CSF)-a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases
    • Reiber H. Flow rate of cerebrospinal fuid (CSF)-a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases. J. Neurol. Sci. 122(2), 189-203 (1994).
    • (1994) J. Neurol. Sci. , vol.122 , Issue.2 , pp. 189-203
    • Reiber, H.1
  • 8
    • 33947632445 scopus 로고    scopus 로고
    • Proteome analysis of cerebrospinal fuid in Guillain-Barré syndrome (GBS)
    • Lehmensiek V, Sussmuth SD, Brettschneider J et al. Proteome analysis of cerebrospinal fuid in Guillain-Barré syndrome (GBS). J. Neuroimmunol. 185(1-2), 190-194 (2007).
    • (2007) J. Neuroimmunol. , vol.185 , Issue.1-2 , pp. 190-194
    • Lehmensiek, V.1    Sussmuth, S.D.2    Brettschneider, J.3
  • 9
    • 35848966977 scopus 로고    scopus 로고
    • Cerebrospinal fuid proteome profle in multiple sclerosis
    • Lehmensiek V, Sussmuth SD, Tauscher G et al. Cerebrospinal fuid proteome profle in multiple sclerosis. Mult. Scler. 13(7), 840-849 (2007).
    • (2007) Mult. Scler. , vol.13 , Issue.7 , pp. 840-849
    • Lehmensiek, V.1    Sussmuth, S.D.2    Tauscher, G.3
  • 10
    • 0027373325 scopus 로고
    • Low frequency of post-lumbar puncture headache in demented patients
    • Blennow K, Wallin A, Hager O. Low frequency of post-lumbar puncture headache in demented patients. Acta Neurol. Scand. 88(3), 221-223 (1993).
    • (1993) Acta Neurol. Scand. , vol.88 , Issue.3 , pp. 221-223
    • Blennow, K.1    Wallin, A.2    Hager, O.3
  • 11
    • 36148965162 scopus 로고    scopus 로고
    • Use of proteomic approaches to identify disease biomarkers
    • Teunissen CE, Scheltens P. Use of proteomic approaches to identify disease biomarkers. Lancet Neurol. 6(12), 1036-1037 (2007).
    • (2007) Lancet Neurol. , vol.6 , Issue.12 , pp. 1036-1037
    • Teunissen, C.E.1    Scheltens, P.2
  • 12
    • 3142676333 scopus 로고    scopus 로고
    • Proteomics for protein expression profling in neuroscience
    • Freeman WM, Hemby SE. Proteomics for protein expression profling in neuroscience. Neurochem. Res. 29(6), 1065-1081 (2004).
    • (2004) Neurochem. Res. , vol.29 , Issue.6 , pp. 1065-1081
    • Freeman, W.M.1    Hemby, S.E.2
  • 13
    • 21244495253 scopus 로고    scopus 로고
    • The development of the DIGE system: 2D fuorescence difference gel analysis technology
    • Marouga R, David S, Hawkins E. The development of the DIGE system: 2D fuorescence difference gel analysis technology. Anal. Bioanal. Chem. 382(3), 669-678 (2005).
    • (2005) Anal. Bioanal. Chem. , vol.382 , Issue.3 , pp. 669-678
    • Marouga, R.1    David, S.2    Hawkins, E.3
  • 14
    • 0343376097 scopus 로고    scopus 로고
    • Difference gel electrophoresis: A single gel method for detecting changes in protein extracts
    • Unlü M, Morgan ME, Minden JS. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 18(11), 2071-2077 (1997).
    • (1997) Electrophoresis , vol.18 , Issue.11 , pp. 2071-2077
    • Unlü, M.1    Morgan, M.E.2    Minden, J.S.3
  • 15
    • 31544471805 scopus 로고    scopus 로고
    • Proteome studies of CSF in AD patients
    • Davidsson P, Sjogren M. Proteome studies of CSF in AD patients. Mech. Ageing Dev. 127(2), 133-137 (2006).
    • (2006) Mech. Ageing Dev. , vol.127 , Issue.2 , pp. 133-137
    • Davidsson, P.1    Sjogren, M.2
  • 16
    • 29244434070 scopus 로고    scopus 로고
    • Comparative proteomic analysis of intra-and interindividual variation in human cerebrospinal fuid
    • Hu Y, Malone JP, Fagan AM, Townsend RR, Holtzman DM. Comparative proteomic analysis of intra-and interindividual variation in human cerebrospinal fuid. Mol. Cell. Proteomics 4(12), 2000-2009 (2005).
    • (2005) Mol. Cell. Proteomics , vol.4 , Issue.12 , pp. 2000-2009
    • Hu, Y.1    Malone, J.P.2    Fagan, A.M.3    Townsend, R.R.4    Holtzman, D.M.5
  • 17
    • 56449084674 scopus 로고    scopus 로고
    • Independent protein-profling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues
    • Huang JT, Wang L, Prabakaran S et al. Independent protein-profling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues. Mol. Psychiatry 13(12), 1118-1128 (2008).
    • (2008) Mol. Psychiatry , vol.13 , Issue.12 , pp. 1118-1128
    • Huang, J.T.1    Wang, L.2    Prabakaran, S.3
  • 18
    • 39749171224 scopus 로고    scopus 로고
    • CSF metabolic and proteomic profles in patients prodromal for psychosis
    • Huang JT, Leweke FM, Tsang TM et al. CSF metabolic and proteomic profles in patients prodromal for psychosis. PLoS ONE 2(1), e756 (2007).
    • (2007) PLoS ONE , vol.2 , Issue.1
    • Huang, J.T.1    Leweke, F.M.2    Tsang, T.M.3
  • 19
    • 34249333883 scopus 로고    scopus 로고
    • Erythropoietin in cerebrospinal fuid: Age-related reference values and relevance in neurological disease
    • Widl K, Brettschneider J, Schattauer D et al. Erythropoietin in cerebrospinal fuid: age-related reference values and relevance in neurological disease. Neurochem. Res. 32(7), 1163-1168 (2007).
    • (2007) Neurochem. Res. , vol.32 , Issue.7 , pp. 1163-1168
    • Widl, K.1    Brettschneider, J.2    Schattauer, D.3
  • 21
    • 0036424643 scopus 로고    scopus 로고
    • Identifcation of proteins in human cerebrospinal fuid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation mass spectrometry
    • Davidsson P, Folkesson S, Christiansson M et al. Identifcation of proteins in human cerebrospinal fuid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation mass spectrometry. Rapid Commun. Mass Spectrom. 16(22), 2083-2088 (2002).
    • (2002) Rapid Commun. Mass Spectrom. , vol.16 , Issue.22 , pp. 2083-2088
    • Davidsson, P.1    Folkesson, S.2    Christiansson, M.3
  • 22
    • 13844310832 scopus 로고    scopus 로고
    • Proteomics analysis of prefractionated human lumbar cerebrospinal fuid
    • Yuan X, Desiderio DM. Proteomics analysis of prefractionated human lumbar cerebrospinal fuid. Proteomics 5(2), 541-550 (2005).
    • (2005) Proteomics , vol.5 , Issue.2 , pp. 541-550
    • Yuan, X.1    Desiderio, D.M.2
  • 23
    • 27744583045 scopus 로고    scopus 로고
    • All about DIGE: Quantifcation technology for differential-display 2D-gel proteomics
    • Lilley KS, Friedman DB. All about DIGE: quantifcation technology for differential-display 2D-gel proteomics. Expert Rev. Proteomics 1(4), 401-409 (2004).
    • (2004) Expert Rev. Proteomics , vol.1 , Issue.4 , pp. 401-409
    • Lilley, K.S.1    Friedman, D.B.2
  • 24
    • 52549129652 scopus 로고    scopus 로고
    • Proteome analysis of cerebrospinal fuid in amyotrophic lateral sclerosis (ALS)
    • Brettschneider J, Mogel H, Lehmensiek V et al. Proteome analysis of cerebrospinal fuid in amyotrophic lateral sclerosis (ALS). Neurochem. Res. 33(11), 2358-2363 (2008).
    • (2008) Neurochem. Res. , vol.33 , Issue.11 , pp. 2358-2363
    • Brettschneider, J.1    Mogel, H.2    Lehmensiek, V.3
  • 25
    • 55749111850 scopus 로고    scopus 로고
    • Cerebrospinal fuid-optimized two-dimensional difference gel electrophoresis (2D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease
    • Brechlin P, Jahn O, Steinacker P et al. Cerebrospinal fuid-optimized two-dimensional difference gel electrophoresis (2D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease. Proteomics 8(20), 4357-4366 (2008).
    • (2008) Proteomics , vol.8 , Issue.20 , pp. 4357-4366
    • Brechlin, P.1    Jahn, O.2    Steinacker, P.3
  • 26
    • 0036463947 scopus 로고    scopus 로고
    • Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system
    • Gharbi S, Gaffney P, Yang A et al. Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system. Mol. Cell. Proteomics 1(2), 91-98 (2002).
    • (2002) Mol. Cell. Proteomics , vol.1 , Issue.2 , pp. 91-98
    • Gharbi, S.1    Gaffney, P.2    Yang, A.3
  • 27
    • 68949157002 scopus 로고    scopus 로고
    • The synergy of elemental and biomolecular mass spectrometry: New analytical strategies in life sciences
    • Becker JS, Jakubowski N. The synergy of elemental and biomolecular mass spectrometry: new analytical strategies in life sciences. Chem. Soc. Rev. 38(7), 1969-1983 (2009).
    • (2009) Chem. Soc. Rev. , vol.38 , Issue.7 , pp. 1969-1983
    • Becker, J.S.1    Jakubowski, N.2
  • 28
    • 84875463071 scopus 로고
    • Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers
    • Hillenkamp F, Karas M, Beavis RC, Chait BT. Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers. Anal. Chem. 63(24), A1193-A1203 (1991).
    • (1991) Anal. Chem. , vol.63 , Issue.24
    • Hillenkamp, F.1    Karas, M.2    Beavis, R.C.3    Chait, B.T.4
  • 29
    • 0028429419 scopus 로고
    • Protein identifcation by peptide mass fngerprinting
    • Cottrell JS. Protein identifcation by peptide mass fngerprinting. Pept. Res. 7(3), 115-124 (1994).
    • (1994) Pept. Res. , vol.7 , Issue.3 , pp. 115-124
    • Cottrell, J.S.1
  • 30
    • 4444335470 scopus 로고    scopus 로고
    • The ABC's (and XYZ's) of peptide sequencing
    • Steen H, Mann M. The ABC's (and XYZ's) of peptide sequencing. Nat. Rev. Mol. Cell Biol. 5(9), 699-711 (2004).
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , Issue.9 , pp. 699-711
    • Steen, H.1    Mann, M.2
  • 31
    • 35348863046 scopus 로고    scopus 로고
    • The application of proteomic techniques to fungal protein identifcation and quantifcation
    • Rohrbough JG, Galgiani JN, Wysocki VH. The application of proteomic techniques to fungal protein identifcation and quantifcation. Ann. NY Acad. Sci. 1111, 133-146 (2007).
    • (2007) Ann. NY Acad. Sci. , vol.1111 , pp. 133-146
    • Rohrbough, J.G.1    Galgiani, J.N.2    Wysocki, V.H.3
  • 32
    • 57349139499 scopus 로고    scopus 로고
    • Utility of mass spectrometry for proteome analysis: Part I. Conceptual and experimental approaches
    • Ahmed FE. Utility of mass spectrometry for proteome analysis: part I. Conceptual and experimental approaches. Expert Rev. Proteomics 5(6), 841-864 (2008).
    • (2008) Expert Rev. Proteomics , vol.5 , Issue.6 , pp. 841-864
    • Ahmed, F.E.1
  • 33
    • 57349120112 scopus 로고    scopus 로고
    • Utility of mass spectrometry for proteome analysis: Part II. Ion-activation methods, statistics, bioinformatics and annotation
    • Ahmed FE. Utility of mass spectrometry for proteome analysis: part II. Ion-activation methods, statistics, bioinformatics and annotation. Expert Rev. Proteomics 6(2), 171-197 (2009).
    • (2009) Expert Rev. Proteomics , vol.6 , Issue.2 , pp. 171-197
    • Ahmed, F.E.1
  • 34
    • 0041358773 scopus 로고    scopus 로고
    • A panel of cerebrospinal fuid potential biomarkers for the diagnosis of Alzheimer's disease
    • Carrette O, Demalte I, Scherl A et al. A panel of cerebrospinal fuid potential biomarkers for the diagnosis of Alzheimer's disease. Proteomics 3(8), 1486-1494 (2003).
    • (2003) Proteomics , vol.3 , Issue.8 , pp. 1486-1494
    • Carrette, O.1    Demalte, I.2    Scherl, A.3
  • 35
    • 0031947586 scopus 로고    scopus 로고
    • Cerebrospinal fuid tau protein as a biochemical marker for Alzheimer's disease: A community based follow up study
    • Andreasen N, Vanmechelen E, Van de Voorde A et al. Cerebrospinal fuid tau protein as a biochemical marker for Alzheimer's disease: a community based follow up study. J. Neurol. Neurosurg. Psychiatry 64(3), 298-305 (1998).
    • (1998) J. Neurol. Neurosurg. Psychiatry , vol.64 , Issue.3 , pp. 298-305
    • Andreasen, N.1    Vanmechelen, E.2    Van De Voorde, A.3
  • 36
    • 35948933394 scopus 로고    scopus 로고
    • Classifcation and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    • Ray S, Britschgi M, Herbert C et al. Classifcation and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat. Med. 13(11), 1359-1362 (2007).
    • (2007) Nat. Med. , vol.13 , Issue.11 , pp. 1359-1362
    • Ray, S.1    Britschgi, M.2    Herbert, C.3
  • 37
    • 25144468377 scopus 로고    scopus 로고
    • Isolated blood-cerebrospinal fuid barrier dysfunction: Prevalence and associated diseases
    • Brettschneider J, Claus A, Kassubek J, Tumani H. Isolated blood-cerebrospinal fuid barrier dysfunction: prevalence and associated diseases. J. Neurol. 252(9), 1067-1073 (2005).
    • (2005) J. Neurol. , vol.252 , Issue.9 , pp. 1067-1073
    • Brettschneider, J.1    Claus, A.2    Kassubek, J.3    Tumani, H.4
  • 38
    • 0037232979 scopus 로고    scopus 로고
    • The STARD statement for reporting studies of diagnostic accuracy: Explanation and elaboration
    • Bossuyt PM, Reitsma JB, Bruns DE et al. The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Clin. Chem. 49(1), 7-18 (2003).
    • (2003) Clin. Chem. , vol.49 , Issue.1 , pp. 7-18
    • Bossuyt, P.M.1    Reitsma, J.B.2    Bruns, D.E.3
  • 39
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME)-toward standards for microarray data
    • Brazma A, Hingamp P, Quackenbush J et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat. Genet. 29(4), 365-371 (2001).
    • (2001) Nat. Genet. , vol.29 , Issue.4 , pp. 365-371
    • Brazma, A.1    Hingamp, P.2    Quackenbush, J.3
  • 41
    • 31344448066 scopus 로고    scopus 로고
    • Guidelines for the next 10 years of proteomics
    • Wilkins MR, Appel RD, Van Eyk JE et al. Guidelines for the next 10 years of proteomics. Proteomics 6(1), 4-8 (2006).
    • (2006) Proteomics , vol.6 , Issue.1 , pp. 4-8
    • Wilkins, M.R.1    Appel, R.D.2    Van Eyk, J.E.3
  • 42
    • 34249062964 scopus 로고    scopus 로고
    • The minimum information about a proteomics experiment (MIAPE)
    • Taylor CF, Paton N W, Lilley KS et al. The minimum information about a proteomics experiment (MIAPE). Nat. Biotechnol. 25(8), 887-893 (2007).
    • (2007) Nat. Biotechnol. , vol.25 , Issue.8 , pp. 887-893
    • Taylor, C.F.1    Paton, N.W.2    Lilley, K.S.3
  • 43
    • 0035289178 scopus 로고    scopus 로고
    • Validation and development of fuorescence two-dimensional differential gel electrophoresis proteomics technology
    • Tonge R, Shaw J, Middleton B et al. Validation and development of fuorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics 1(3), 377-396 (2001).
    • (2001) Proteomics , vol.1 , Issue.3 , pp. 377-396
    • Tonge, R.1    Shaw, J.2    Middleton, B.3
  • 44
    • 36349014934 scopus 로고    scopus 로고
    • Cerebrospinal fuid proteomic profling of HIV-1-infected patients with cognitive impairment
    • Rozek W, Ricardo-Dukelow M, Holloway S et al. Cerebrospinal fuid proteomic profling of HIV-1-infected patients with cognitive impairment. J. Proteome Res. 6(11), 4189-4199 (2007).
    • (2007) J. Proteome Res. , vol.6 , Issue.11 , pp. 4189-4199
    • Rozek, W.1    Ricardo-Dukelow, M.2    Holloway, S.3
  • 45
    • 33846787156 scopus 로고    scopus 로고
    • A gel-based proteomic comparison of human cerebrospinal fuid between inficted and non-inficted pediatric traumatic brain injury
    • Gao WM, Chadha MS, Berger RP et al. A gel-based proteomic comparison of human cerebrospinal fuid between inficted and non-inficted pediatric traumatic brain injury. J. Neurotrauma 24(1), 43-53 (2007).
    • (2007) J. Neurotrauma , vol.24 , Issue.1 , pp. 43-53
    • Gao, W.M.1    Chadha, M.S.2    Berger, R.P.3
  • 46
    • 34247139196 scopus 로고    scopus 로고
    • Proteomic identifcation of potential protein markers in cerebrospinal fuid of GBS patients
    • Jin T, Hu LS, Chang M, Wu J, Winblad B, Zhu J. Proteomic identifcation of potential protein markers in cerebrospinal fuid of GBS patients. Eur. J. Neurol. 14(5), 563-568 (2007).
    • (2007) Eur. J. Neurol. , vol.14 , Issue.5 , pp. 563-568
    • Jin, T.1    Hu, L.S.2    Chang, M.3    Wu, J.4    Winblad, B.5    Zhu, J.6
  • 47
    • 60049100278 scopus 로고    scopus 로고
    • Alteration of DBP levels in CSF of patients with MS by proteomics analysis
    • Qin Z, Qin Y, Liu S. Alteration of DBP levels in CSF of patients with MS by proteomics analysis. Cell. Mol. Neurobiol. 29(2), 203-210 (2009).
    • (2009) Cell. Mol. Neurobiol. , vol.29 , Issue.2 , pp. 203-210
    • Qin, Z.1    Qin, Y.2    Liu, S.3
  • 48
    • 70349306691 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of the cerebrospinal fuid of patients with multiple sclerosis
    • Liu S, Bai S, Qin Z, Yang Y, Cui Y, Qin Y. Quantitative proteomic analysis of the cerebrospinal fuid of patients with multiple sclerosis. J. Cell. Mol. Med. 13(8A), 1586-1603 (2009).
    • (2009) J. Cell. Mol. Med. , vol.13 , Issue.8 A , pp. 1586-1603
    • Liu, S.1    Bai, S.2    Qin, Z.3    Yang, Y.4    Cui, Y.5    Qin, Y.6
  • 49
    • 68149157428 scopus 로고    scopus 로고
    • Preliminary analysis of cerebrospinal fuid proteome in patients with neurocysticercosis
    • Tian XJ, Li JY, Huang Y, Xue Y P. Preliminary analysis of cerebrospinal fuid proteome in patients with neurocysticercosis. Chin. Med. J. (Engl.) 122(9), 1003-1008 (2009).
    • (2009) Chin. Med. J. (Engl.) , vol.122 , Issue.9 , pp. 1003-1008
    • Tian, X.J.1    Li, J.Y.2    Huang, Y.3    Xue, Y.P.4
  • 50
    • 0017572709 scopus 로고
    • Principles of albumin and IgG analyses in neurological disorders. III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis
    • Link H, Tibbling G. Principles of albumin and IgG analyses in neurological disorders. III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis. Scand. J. Clin. Lab. Invest. 37(5), 397-401 (1977).
    • (1977) Scand. J. Clin. Lab. Invest. , vol.37 , Issue.5 , pp. 397-401
    • Link, H.1    Tibbling, G.2
  • 51
    • 0023112582 scopus 로고
    • Protein transfer at the blood cerebrospinal fuid barrier and the quantitation of the humoral immune response within the central nervous system
    • Reiber H, Felgenhauer K. Protein transfer at the blood cerebrospinal fuid barrier and the quantitation of the humoral immune response within the central nervous system. Clin. Chim. Acta. 163(3), 319-328 (1987).
    • (1987) Clin. Chim. Acta. , vol.163 , Issue.3 , pp. 319-328
    • Reiber, H.1    Felgenhauer, K.2
  • 52
    • 0035282811 scopus 로고    scopus 로고
    • Cerebrospinal fuid analysis: Disease-related data patterns and evaluation programs
    • Reiber H, Peter JB. Cerebrospinal fuid analysis: disease-related data patterns and evaluation programs. J. Neurol. Sci. 184(2), 101-122 (2001).
    • (2001) J. Neurol. Sci. , vol.184 , Issue.2 , pp. 101-122
    • Reiber, H.1    Peter, J.B.2


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