Erythropoietin in cerebrospinal fluid: Age-related reference values and relevance in neurological disease

Neurochemical Research

Volumn 32, Issue 7, 2007, Pages 1163-1168

  Widl, Karin ^a   Brettschneider, Johannes ^a   Schattauer, Dagmar ^a   Süßmuth, Sigurd ^a   Huber, Roman ^a   Ludolph, Albert C ^a   Tumani, Hayrettin ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Age relation; Cerebrospinal fluid; Erythropoietin; Reference values

Indexed keywords

ERYTHROPOIETIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; DEPRESSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FREEZING; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TENSION HEADACHE; THAWING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; DEPRESSION; ERYTHROPOIETIN; HUMANS; MIDDLE AGED; NERVOUS SYSTEM DISEASES; REFERENCE VALUES; TENSION-TYPE HEADACHE;

EID: 34249333883     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9286-0     Document Type: Article

References (27)

1. Brines ML, Ghezzi P, Keenan S et al (2000) Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA 97:10526-10531
2. Juul SE, Anderson DK, Li Y et al (1998) Erythropoietin and erythropoietin receptor in the developing human central nervous system. Pediatr Res 43:40-49
3. Marti HH (2004) Erythropoietin and the hypoxic brain. J Exp Biol 207:3233-3242
4. Buemi M, Cavallaro E, Floccari F et al (2002) Erythropoietin and the brain: from neurodevelopment to neuroprotection. Clin Sci (Lond) 103:275-282
5. Knabe W, Knerlich F, Washausen S et al (2004) Expression patterns of erythropoietin and its receptor in the developing midbrain. Anat Embryol (Berl) 207:503-512
6. Sakanaka M, Wen TC, Matsuda S et al (1998) In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc Natl Acad Sci USA 95:4635-4640
7. Agnello D, Bigini P, Villa P et al (2002) Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res 952:128-134
8. Eid TBrines M (2002) Recombinant human erythropoietin for neuroprotection: what is the evidence? Clin. Breast Cancer 3(Suppl 3):S109-115
9. Brooks BR, Miller RG, Swash M et al (2000) El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:293-299
10. Strong M, Rosenfeld J (2003) Amyotrophic lateral sclerosis: a review of current concepts. Amyotroph Lateral Scler Other Motor Neuron Disord 4:136-143
11. McKhann G, Drachman D, Folstein M et al (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34:939-944
12. Neary D, Snowden JS, Gustafson L et al (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546-1554
13. Roman GC, Tatemichi TK, Erkinjuntti T et al (1993) Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN international workshop. Neurology 43:250-260
14. Petersen RC, Smith GE, Waring SC et al (1997) Aging, memory, and mild cognitive impairment. Int Psychogeriatr1:(Suppl 9) 65-69
15. Sussmuth SD, Tumani H, Ecker D et al (2003) Amyotrophic lateral sclerosis: disease stage related changes of tau protein and S100 beta in cerebrospinal fluid and creatine kinase in serum. Neurosci Lett 353:57-60
16. Felgenhauer K (1974) Protein size and cerebrospinal fluid composition. Klin Wochenschr 52:1158-1164
17. Fisher JW (2003) Erythropoietin: physiology and pharmacology update. Exp Biol Med (Maywood) 228:1-14
18. Xenocostas A, Cheung WK, Farrell F et al (2005) The pharmacokinetics of erythropoietin in the cerebrospinal fluid after intravenous administration of recombinant human erythropoietin. Eur J Clin Pharmacol 61:189-195
19. Nakamura T, Ebihara I, Shimada N et al (1998) Elevated levels of erythropoietin in cerebrospinal fluid of depressed patients. Am J Med Sci 315:199-201
20. Juul SE, Harcum J, Li Y et al (1997) Erythropoietin is present in the cerebrospinal fluid of neonates. J Pediatr 130:428-430
21. van Engelen BG, Lamers KJ, Gabreels FJ et al (1992) Age-related changes of neuron-specific enolase, S-100 protein, and myelin basic protein concentrations in cerebrospinal fluid. Clin Chem 38:813-816
22. May C, Kaye JA, Atack JR et al (1990) Cerebrospinal fluid production is reduced in healthy aging. Neurology 40:500-503
23. Eckardt KU, Kurtz A, Hirth P et al (1988) Evaluation of the stability of human erythropoietin in samples for radioimmunoassay. Klin Wochenschr 66:241-245
24. Springborg JB, Sonne B, Frederiksen HJ et al (2003) Erythropoietin in the cerebrospinal fluid of patients with aneurysmal subarachnoid haemorrhage originates from the brain. Brain Res 984:143-148
25. Sussmuth SD, Reiber H, Tumani H (2001) Tau protein in cerebrospinal fluid (CSF): a blood-CSF barrier related evaluation in patients with various neurological diseases. Neurosci Lett 300:95-98
26. Ehrenreich H, Hasselblatt M, Dembowski C et al (2002) Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 8:495-505
27. Ehrenreich H, Aust C, Krampe H et al (2004) Erythropoietin: novel approaches to neuroprotection in human brain disease. Metab Brain Dis 19:195-206