-
1
-
-
14144253009
-
Mechanisms of resistance of malaria parasites to antifolates
-
Gregson A., and Plowe C.V. Mechanisms of resistance of malaria parasites to antifolates. Pharmacol. Rev. 57 (2005) 117-145
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 117-145
-
-
Gregson, A.1
Plowe, C.V.2
-
2
-
-
0033636607
-
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
-
Fidock D.A., Nomura T., Talley A.K., Cooper R.A., Dzekunov S.M., Ferdig M.T., et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell 6 (2000) 861-871
-
(2000)
Mol Cell
, vol.6
, pp. 861-871
-
-
Fidock, D.A.1
Nomura, T.2
Talley, A.K.3
Cooper, R.A.4
Dzekunov, S.M.5
Ferdig, M.T.6
-
3
-
-
0025269612
-
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
-
Foote S.J., Kyle D.E., Martin R.K., Oduola A.M., Forsyth K., Kemp D.J., et al. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345 (1990) 255-258
-
(1990)
Nature
, vol.345
, pp. 255-258
-
-
Foote, S.J.1
Kyle, D.E.2
Martin, R.K.3
Oduola, A.M.4
Forsyth, K.5
Kemp, D.J.6
-
4
-
-
0034732666
-
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin
-
Duraisingh M.T., Jones P., Sambou I., von Seidlein L., Pinder M., and Warhurst D.C. The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. Mol. Biochem. Parasitol. 108 (2000) 13-23
-
(2000)
Mol. Biochem. Parasitol.
, vol.108
, pp. 13-23
-
-
Duraisingh, M.T.1
Jones, P.2
Sambou, I.3
von Seidlein, L.4
Pinder, M.5
Warhurst, D.C.6
-
5
-
-
0000841123
-
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
-
Peterson D.S., Walliker D., and Wellems T.E. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci U S A 85 (1988) 9114-9118
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 9114-9118
-
-
Peterson, D.S.1
Walliker, D.2
Wellems, T.E.3
-
6
-
-
0030720799
-
Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance
-
Plowe C.V., Cortese J.F., Djimde A., Nwanyanwu O.C., Watkins W.M., Winstanley P.A., et al. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. J Infect Dis 176 (1997) 1590-1596
-
(1997)
J Infect Dis
, vol.176
, pp. 1590-1596
-
-
Plowe, C.V.1
Cortese, J.F.2
Djimde, A.3
Nwanyanwu, O.C.4
Watkins, W.M.5
Winstanley, P.A.6
-
7
-
-
67749098058
-
Stepwise acquisition of pyrimethamine resistance in the malaria parasite
-
Lozovsky E.R., Chookajorn T., Brown K.M., Imwong M., Shaw P.J., Kamchonwongpaisan S., et al. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc Natl Acad Sci U S A 106 (2009) 12025-12030
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12025-12030
-
-
Lozovsky, E.R.1
Chookajorn, T.2
Brown, K.M.3
Imwong, M.4
Shaw, P.J.5
Kamchonwongpaisan, S.6
-
8
-
-
0029013280
-
A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum
-
Wang P., Brooks D.R., Sims P.F., and Hyde J.E. A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum. Mol. Biochem. Parasitol. 71 (1995) 115-125
-
(1995)
Mol. Biochem. Parasitol.
, vol.71
, pp. 115-125
-
-
Wang, P.1
Brooks, D.R.2
Sims, P.F.3
Hyde, J.E.4
-
9
-
-
0031444278
-
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum
-
Triglia T., Menting J.G., Wilson C., and Cowman A.F. Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A 94 (1997) 13944-13949
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13944-13949
-
-
Triglia, T.1
Menting, J.G.2
Wilson, C.3
Cowman, A.F.4
-
11
-
-
0034968575
-
Short report: differences in dihydrofolate reductase but not dihydropteroate synthase alleles in Plasmodium falciparum isolates from geographically distinct areas in Malaysia
-
Cox-Singh J., Zakaria R., Abdullah M.S., Rahman H.A., Nagappan S., and Singh B. Short report: differences in dihydrofolate reductase but not dihydropteroate synthase alleles in Plasmodium falciparum isolates from geographically distinct areas in Malaysia. Am. J. Trop. Med. Hyg. 64 (2001) 28-31
-
(2001)
Am. J. Trop. Med. Hyg.
, vol.64
, pp. 28-31
-
-
Cox-Singh, J.1
Zakaria, R.2
Abdullah, M.S.3
Rahman, H.A.4
Nagappan, S.5
Singh, B.6
-
12
-
-
3042644635
-
Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh
-
Van Den Broek I.V., Van Der Wardt S., Talukder L., Chakma S., Brockman A., Nair S., et al. Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh. Trop. Med. Int. Health 9 (2004) 680-687
-
(2004)
Trop. Med. Int. Health
, vol.9
, pp. 680-687
-
-
Van Den Broek, I.V.1
Van Der Wardt, S.2
Talukder, L.3
Chakma, S.4
Brockman, A.5
Nair, S.6
-
13
-
-
0027420335
-
High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction
-
Snounou G., Viriyakosol S., Zhu X.P., Jarra W., Pinheiro L., do Rosario V.E., et al. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol. Biochem. Parasitol. 61 (1993) 315-320
-
(1993)
Mol. Biochem. Parasitol.
, vol.61
, pp. 315-320
-
-
Snounou, G.1
Viriyakosol, S.2
Zhu, X.P.3
Jarra, W.4
Pinheiro, L.5
do Rosario, V.E.6
-
14
-
-
0032079104
-
Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion
-
Duraisingh M.T., Curtis J., and Warhurst D.C. Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion. Exp. Parasitol. 89 (1998) 1-8
-
(1998)
Exp. Parasitol.
, vol.89
, pp. 1-8
-
-
Duraisingh, M.T.1
Curtis, J.2
Warhurst, D.C.3
-
15
-
-
0035945682
-
A molecular marker for chloroquine-resistant falciparum malaria
-
Djimde A., Doumbo O.K., Cortese J.F., Kayentao K., Doumbo S., Diourte Y., et al. A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med 344 (2001) 257-263
-
(2001)
N Engl J Med
, vol.344
, pp. 257-263
-
-
Djimde, A.1
Doumbo, O.K.2
Cortese, J.F.3
Kayentao, K.4
Doumbo, S.5
Diourte, Y.6
-
16
-
-
10744222802
-
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites
-
Nair S., Williams J.T., Brockman A., Paiphun L., Mayxay M., Newton P.N., Newton P.N., et al. A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites. Mol. Biol. Evol. 20 (2003) 1526-1536
-
(2003)
Mol. Biol. Evol.
, vol.20
, pp. 1526-1536
-
-
Nair, S.1
Williams, J.T.2
Brockman, A.3
Paiphun, L.4
Mayxay, M.5
Newton, P.N.6
Newton, P.N.7
-
17
-
-
33847629236
-
Independent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in Melanesia
-
Mita T., Tanabe K., Takahashi N., Tsukahara T., Eto H., Dysoley L., et al. Independent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in Melanesia. Antimicrob. Agents Chemother. 51 (2007) 1071-1077
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 1071-1077
-
-
Mita, T.1
Tanabe, K.2
Takahashi, N.3
Tsukahara, T.4
Eto, H.5
Dysoley, L.6
-
18
-
-
27844584255
-
Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites
-
Anderson T.J., Nair S., Sudimack D., Williams J.T., Mayxay M., Newton P.N., et al. Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites. Mol. Biol. Evol. 22 (2005) 2362-2374
-
(2005)
Mol. Biol. Evol.
, vol.22
, pp. 2362-2374
-
-
Anderson, T.J.1
Nair, S.2
Sudimack, D.3
Williams, J.T.4
Mayxay, M.5
Newton, P.N.6
-
19
-
-
1442300135
-
Plasmodium falciparum isolates in india exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance
-
Ahmed A., Bararia D., Vinayak S., Yameen M., Biswas S., Dev V., et al. Plasmodium falciparum isolates in india exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance. Antimicrob. Agents Chemother. 48 (2004) 879-889
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 879-889
-
-
Ahmed, A.1
Bararia, D.2
Vinayak, S.3
Yameen, M.4
Biswas, S.5
Dev, V.6
-
20
-
-
2442614219
-
Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiology
-
Wernsdorfer W.H., and Noedl H. Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiology. Curr Opin Infect Dis 16 (2003) 553-558
-
(2003)
Curr Opin Infect Dis
, vol.16
, pp. 553-558
-
-
Wernsdorfer, W.H.1
Noedl, H.2
-
21
-
-
0038095204
-
Prevalence of the K76T mutation in the pfcrt gene of Plasmodium falciparum among chloroquine responders in India
-
Vinayak S., Biswas S., Dev V., Kumar A., Ansari M.A., and Sharma Y.D. Prevalence of the K76T mutation in the pfcrt gene of Plasmodium falciparum among chloroquine responders in India. Acta Trop. 87 (2003) 287-293
-
(2003)
Acta Trop.
, vol.87
, pp. 287-293
-
-
Vinayak, S.1
Biswas, S.2
Dev, V.3
Kumar, A.4
Ansari, M.A.5
Sharma, Y.D.6
-
22
-
-
33646072188
-
Progressive increase in point mutations associated with chloroquine resistance in Plasmodium falciparum isolates from India
-
Mittra P., Vinayak S., Chandawat H., Das M.K., Singh N., Biswas S., et al. Progressive increase in point mutations associated with chloroquine resistance in Plasmodium falciparum isolates from India. J Infect Dis 193 (2006) 1304-1312
-
(2006)
J Infect Dis
, vol.193
, pp. 1304-1312
-
-
Mittra, P.1
Vinayak, S.2
Chandawat, H.3
Das, M.K.4
Singh, N.5
Biswas, S.6
-
23
-
-
67649194603
-
Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India
-
Valecha N., Srivastava P., Mohanty S.S., Mittra P., Sharma S.K., Tyagi P.K., et al. Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India. Malar J 8 (2009) 107
-
(2009)
Malar J
, vol.8
, pp. 107
-
-
Valecha, N.1
Srivastava, P.2
Mohanty, S.S.3
Mittra, P.4
Sharma, S.K.5
Tyagi, P.K.6
-
24
-
-
0035873715
-
High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1
-
Babiker H.A., Pringle S.J., Abdel-Muhsin A., Mackinnon M., Hunt P., and Walliker D. High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1. J Infect Dis 183 (2001) 1535-1538
-
(2001)
J Infect Dis
, vol.183
, pp. 1535-1538
-
-
Babiker, H.A.1
Pringle, S.J.2
Abdel-Muhsin, A.3
Mackinnon, M.4
Hunt, P.5
Walliker, D.6
-
25
-
-
33646883694
-
Role of pfmdr1 mutations on chloroquine resistance in Plasmodium falciparum isolates with pfcrt K76T from Papua New Guinea
-
Mita T., Kaneko A., Hombhanje F., Hwaihwangje I., Takahashi N., Osawa H., et al. Role of pfmdr1 mutations on chloroquine resistance in Plasmodium falciparum isolates with pfcrt K76T from Papua New Guinea. Acta Trop. 98 (2006) 137-144
-
(2006)
Acta Trop.
, vol.98
, pp. 137-144
-
-
Mita, T.1
Kaneko, A.2
Hombhanje, F.3
Hwaihwangje, I.4
Takahashi, N.5
Osawa, H.6
-
26
-
-
0038239207
-
Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi
-
Kublin J.G., Cortese J.F., Njunju E.M., Mukadam R.A., Wirima J.J., Kazembe P.N., et al. Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J Infect Dis 187 (2003) 1870-1875
-
(2003)
J Infect Dis
, vol.187
, pp. 1870-1875
-
-
Kublin, J.G.1
Cortese, J.F.2
Njunju, E.M.3
Mukadam, R.A.4
Wirima, J.J.5
Kazembe, P.N.6
-
27
-
-
14844327986
-
In vivo selection of Plasmodium falciparum pfmdr1 86 N coding alleles by artemether-lumefantrine (coartem)
-
Sisowath C., Stromberg J., Martensson A., Msellem M., Obondo C., Bjorkman A., et al. In vivo selection of Plasmodium falciparum pfmdr1 86 N coding alleles by artemether-lumefantrine (coartem). J Infect Dis 191 (2005) 1014-1017
-
(2005)
J Infect Dis
, vol.191
, pp. 1014-1017
-
-
Sisowath, C.1
Stromberg, J.2
Martensson, A.3
Msellem, M.4
Obondo, C.5
Bjorkman, A.6
-
28
-
-
3242704083
-
Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand
-
Lopes D., Rungsihirunrat K., Nogueira F., Seugorn A., Gil J.P., do Rosario V.E., et al. Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand. Malar J 1 (2002) 12
-
(2002)
Malar J
, vol.1
, pp. 12
-
-
Lopes, D.1
Rungsihirunrat, K.2
Nogueira, F.3
Seugorn, A.4
Gil, J.P.5
do Rosario, V.E.6
-
29
-
-
56949096093
-
Association between chloroquine resistance phenotypes and point mutations in pfcrt and pfmdr1 in Plasmodium falciparum isolates from Thailand
-
Rungsihirunrat K., Chaijareonkul W., Seugorn A., Na-Bangchang K., and Thaithong S. Association between chloroquine resistance phenotypes and point mutations in pfcrt and pfmdr1 in Plasmodium falciparum isolates from Thailand. Acta Trop. 109 (2009) 37-40
-
(2009)
Acta Trop.
, vol.109
, pp. 37-40
-
-
Rungsihirunrat, K.1
Chaijareonkul, W.2
Seugorn, A.3
Na-Bangchang, K.4
Thaithong, S.5
-
30
-
-
0035214291
-
In vitro susceptibility of Plasmodium falciparum isolates from Myanmar to antimalarial drugs
-
Wongsrichanalai C., Lin K., Pang L.W., Faiz M.A., Noedl H., Wimonwattrawatee T., et al. In vitro susceptibility of Plasmodium falciparum isolates from Myanmar to antimalarial drugs. Am. J. Trop. Med. Hyg. 65 (2001) 450-455
-
(2001)
Am. J. Trop. Med. Hyg.
, vol.65
, pp. 450-455
-
-
Wongsrichanalai, C.1
Lin, K.2
Pang, L.W.3
Faiz, M.A.4
Noedl, H.5
Wimonwattrawatee, T.6
-
31
-
-
2142769136
-
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
-
Price R.N., Uhlemann A.C., Brockman A., McGready R., Ashley E., Phaipun L., et al. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. Lancet 364 (2004) 438-447
-
(2004)
Lancet
, vol.364
, pp. 438-447
-
-
Price, R.N.1
Uhlemann, A.C.2
Brockman, A.3
McGready, R.4
Ashley, E.5
Phaipun, L.6
-
32
-
-
65649106581
-
Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness
-
Preechapornkul P., Imwong M., Chotivanich K., Pongtavornpinyo W., Dondorp A.M., Day N.P., et al. Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness. Antimicrob. Agents Chemother. 53 (2009) 1509-1515
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 1509-1515
-
-
Preechapornkul, P.1
Imwong, M.2
Chotivanich, K.3
Pongtavornpinyo, W.4
Dondorp, A.M.5
Day, N.P.6
-
33
-
-
0033775025
-
The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya
-
Mberu E.K., Mosobo M.K., Nzila A.M., Kokwaro G.O., Sibley C.H., and Watkins W.M. The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya. Am. J. Trop. Med. Hyg. 62 (2000) 396-401
-
(2000)
Am. J. Trop. Med. Hyg.
, vol.62
, pp. 396-401
-
-
Mberu, E.K.1
Mosobo, M.K.2
Nzila, A.M.3
Kokwaro, G.O.4
Sibley, C.H.5
Watkins, W.M.6
|