In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces disruption of glands of the prostate and fibrosis in rhesus monkeys

Reproductive Toxicology

Volumn 29, Issue 3, 2010, Pages 317-322

  Arima, Akihiro ^a,b   Kato, Hirohito ^a   Ise, Ryota ^a   Ooshima, Yojiro ^a   Inoue, Ayumi ^a   Muneoka, Atsunobu ^a   Kamimura, Shunichi ^b,c   Fukusato, Toshio ^d   Kubota, Shunichiro ^e   Sumida, Hiroshi ^f   Yasuda, Mineo ^f  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

^c UNIVERSITY OF MIYAZAKI   (Japan)

^d TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

Fibrosis; Inflammatory response; Microarray; Offspring; Prostate; Prostatic dysfunction; Rhesus monkey; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; COLLAGEN TYPE 1; GELATINASE A; MESSENGER RNA; PROTEIN COL1A1; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN TGM4; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; FIBROSIS; GENE CONTROL; GENE EXPRESSION; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY CELL; LACTATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENATAL EXPOSURE; PROSTATE DISEASE; RHESUS MONKEY; SEXUAL MATURATION; TOXICOKINETICS; UPREGULATION;

ANIMALS; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROSIS; LACTATION; MACACA MULATTA; MALE; MUSCULOSKELETAL SYSTEM; PREGNANCY; PROSTATE; SEMEN ANALYSIS; TETRACHLORODIBENZODIOXIN; UP-REGULATION;

MACACA MULATTA;

EID: 77951620715     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2009.12.007     Document Type: Article

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