메뉴 건너뛰기




Volumn 125, Issue 7, 2009, Pages 1505-1513

Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo

Author keywords

ECRG4; ESCC; Prognosis; Tumor suppressor

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLOOXYGENASE 2; ESOPHAGEAL CANCER RELATED GENE 4 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 68549103547     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24513     Document Type: Article
Times cited : (94)

References (35)
  • 2
    • 33845485257 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of esophageal cancer
    • Holmes RS, Vaughan TL. Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol 2007;17:2-9.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 2-9
    • Holmes, R.S.1    Vaughan, T.L.2
  • 3
    • 1442351994 scopus 로고    scopus 로고
    • Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray
    • Luo A, Kong J, Hu G, Liew CC, Xiong M, Wang X, Ji J, Wang T, Zhi H, Wu M, Liu Z. Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene 2004;23:1291-9.
    • (2004) Oncogene , vol.23 , pp. 1291-1299
    • Luo, A.1    Kong, J.2    Hu, G.3    Liew, C.C.4    Xiong, M.5    Wang, X.6    Ji, J.7    Wang, T.8    Zhi, H.9    Wu, M.10    Liu, Z.11
  • 6
    • 0031722319 scopus 로고    scopus 로고
    • Cloning and identification of cDNA fragments related to human esophageal cancer
    • Su T, Liu H, Lu S. Cloning and identification of cDNA fragments related to human esophageal cancer. China J Oncol 1998;20:254-7.
    • (1998) China J Oncol , vol.20 , pp. 254-257
    • Su, T.1    Liu, H.2    Lu, S.3
  • 7
    • 0036433413 scopus 로고    scopus 로고
    • Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage
    • Steck E, Breit S, Breusch SJ, Axt M, Richter W. Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage. Biochem Biophys Res Commun 2002;299:109-15.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 109-115
    • Steck, E.1    Breit, S.2    Breusch, S.J.3    Axt, M.4    Richter, W.5
  • 8
    • 0037714882 scopus 로고    scopus 로고
    • Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma
    • Yue CM, Deng DJ, Bi MX, Guo LP, Lu SH. Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. World J Gastroenterol 2003;9:1174-8.
    • (2003) World J Gastroenterol , vol.9 , pp. 1174-1178
    • Yue, C.M.1    Deng, D.J.2    Bi, M.X.3    Guo, L.P.4    Lu, S.H.5
  • 10
    • 36148961616 scopus 로고    scopus 로고
    • ECRG2 inhibits cancer cell migration, invasion and metastasis through the downregulation of uPA/plasmin activity
    • Huang G, Hu Z, Li M, Cui Y, Li Y, Guo L, Jiang W, Lu SH. ECRG2 inhibits cancer cell migration, invasion and metastasis through the downregulation of uPA/plasmin activity. Carcinogenesis 2007;28:2274-81.
    • (2007) Carcinogenesis , vol.28 , pp. 2274-2281
    • Huang, G.1    Hu, Z.2    Li, M.3    Cui, Y.4    Li, Y.5    Guo, L.6    Jiang, W.7    Lu, S.H.8
  • 14
    • 0036147076 scopus 로고    scopus 로고
    • Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: Molecular basis of its occurrence
    • Thiagalingam S, Foy RL, Cheng KH, Lee HJ, Thiagalingam A, Ponte JF. Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence. Curr Opin Oncol 2002;14:65-72.
    • (2002) Curr Opin Oncol , vol.14 , pp. 65-72
    • Thiagalingam, S.1    Foy, R.L.2    Cheng, K.H.3    Lee, H.J.4    Thiagalingam, A.5    Ponte, J.F.6
  • 15
    • 0035576196 scopus 로고    scopus 로고
    • Comparative genomic hybridization of esophageal squamous cell carcinoma: Correlations between chromosomal aberrations and disease progression/prognosis
    • Yen CC, Chen YJ, Chen JT, Hsia JY, Chen PM, Liu JH, Fan FS, Chiou TJ, Wang WS, Lin CH. Comparative genomic hybridization of esophageal squamous cell carcinoma: correlations between chromosomal aberrations and disease progression/prognosis. Cancer 2001;92:2769-77.
    • (2001) Cancer , vol.92 , pp. 2769-2777
    • Yen, C.C.1    Chen, Y.J.2    Chen, J.T.3    Hsia, J.Y.4    Chen, P.M.5    Liu, J.H.6    Fan, F.S.7    Chiou, T.J.8    Wang, W.S.9    Lin, C.H.10
  • 16
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-28.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 17
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003;349:2042-54.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 18
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003;3:253-66.
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 19
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004;429:457-63.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 20
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?. Nat Rev Cancer 2006;6:107-16.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 21
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006;7:21-33.
    • (2006) Nat Rev Genet , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 22
    • 0038756374 scopus 로고    scopus 로고
    • Allele loss and promoter hypermethylation of VHL. RAR-beta RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma
    • Kuroki T, Trapasso F, Yendamuri S, Matsuyama A, Alder H, Mori M, Croce CM. Allele loss and promoter hypermethylation of VHL. RAR-beta RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 2003;63:3724-8.
    • (2003) Cancer Res , vol.63 , pp. 3724-3728
    • Kuroki, T.1    Trapasso, F.2    Yendamuri, S.3    Matsuyama, A.4    Alder, H.5    Mori, M.6    Croce, C.M.7
  • 23
    • 0023796588 scopus 로고
    • Amplification of the EGF receptor and c-myc genes in human esophageal cancers
    • Lu SH, Hsieh LL, Luo FC, Weinstein IB. Amplification of the EGF receptor and c-myc genes in human esophageal cancers. Int J Cancer 1988;42:502-5.
    • (1988) Int J Cancer , vol.42 , pp. 502-505
    • Lu, S.H.1    Hsieh, L.L.2    Luo, F.C.3    Weinstein, I.B.4
  • 24
    • 0029665180 scopus 로고    scopus 로고
    • Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: A review
    • Montesano R, Hollstein M, Hainaut P. Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review. Int J Cancer 1996;69:225-35.
    • (1996) Int J Cancer , vol.69 , pp. 225-235
    • Montesano, R.1    Hollstein, M.2    Hainaut, P.3
  • 25
    • 0032589744 scopus 로고    scopus 로고
    • Mechanisms of inactivation of p14ARF, p15INK4b and p16INK4a genes in human esophageal squamous cell carcinoma
    • Xing EP, Nie Y, Song Y, Yang GY, Cai YC, Wang LD, Yang CS. Mechanisms of inactivation of p14ARF, p15INK4b and p16INK4a genes in human esophageal squamous cell carcinoma. Clin Cancer Res 1999;5:2704-13.
    • (1999) Clin Cancer Res , vol.5 , pp. 2704-2713
    • Xing, E.P.1    Nie, Y.2    Song, Y.3    Yang, G.Y.4    Cai, Y.C.5    Wang, L.D.6    Yang, C.S.7
  • 26
    • 0032145266 scopus 로고    scopus 로고
    • Methylation of the 50 CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas
    • Tanaka H, Shimada Y, Harada H, Shinoda M, Hatooka S, Imamura M, Ishizaki K. Methylation of the 50 CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res 1998;58:3429-34.
    • (1998) Cancer Res , vol.58 , pp. 3429-3434
    • Tanaka, H.1    Shimada, Y.2    Harada, H.3    Shinoda, M.4    Hatooka, S.5    Imamura, M.6    Ishizaki, K.7
  • 27
    • 0035829016 scopus 로고    scopus 로고
    • E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells
    • Si HX, Tsao SW, Lam KY, Srivastava G, Liu Y, Wong YC, Shen ZY, Cheung AL. E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells. Cancer lett 2001;173:71-8.
    • (2001) Cancer lett , vol.173 , pp. 71-78
    • Si, H.X.1    Tsao, S.W.2    Lam, K.Y.3    Srivastava, G.4    Liu, Y.5    Wong, Y.C.6    Shen, Z.Y.7    Cheung, A.L.8
  • 28
    • 0038687773 scopus 로고    scopus 로고
    • Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma
    • Zhang L, Lu W, Miao X, Xing D, Tan W, Lin D. Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma. Carcinogenesis 2003;24:1039-44.
    • (2003) Carcinogenesis , vol.24 , pp. 1039-1044
    • Zhang, L.1    Lu, W.2    Miao, X.3    Xing, D.4    Tan, W.5    Lin, D.6
  • 30
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301-10.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 33
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention
    • Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-100.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1089-1100
    • Chun, K.S.1    Surh, Y.J.2
  • 34
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
    • Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer cell 2004;6:297-305.
    • (2004) Cancer cell , vol.6 , pp. 297-305
    • Luo, J.L.1    Maeda, S.2    Hsu, L.C.3    Yagita, H.4    Karin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.