Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis

Journal of Biological Chemistry

Volumn 285, Issue 18, 2010, Pages 13827-13838

  Widau, Ryan C ^a   Jin, Yijun ^b   Dixon, Shelley A ^a   Wadzinski, Brian E ^c   Gallagher, Patricia J ^a  

^a INDIANA UNIVERSITY   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANOIKIS; AUTOPHOSPHORYLATION; CALMODULIN BINDING DOMAIN; CATALYTIC ACTIVITY; CELL ROUNDING; CERAMIDES; CONTROL-CELL; CYTOSKELETAL DYNAMICS; DEATH-ASSOCIATED PROTEINS; DEPHOSPHORYLATIONS; ENZYMATIC ACTIVITIES; HEK293 CELLS; IN-VITRO; KINASE ACTIVITY; OVER-EXPRESSION; PROTEASOMES; PROTEIN PHOSPHATASE 2A; TUMOR SUPPRESSORS; WILD TYPES;

ADHESION; AMIDES; CALCIUM; CALMODULIN; CELL ADHESION; DEGRADATION;

PHOSPHATASES;

CERAMIDE; DEATH ASSOCIATED PROTEIN KINASE; HOLOENZYME; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2A REGULATORY B ALPHA SUBUNIT C; PHOSPHOPROTEIN PHOSPHATASE 2A REGULATORY B DELTA SUBUNIT C; UNCLASSIFIED DRUG;

ANOIKIS; APOPTOSIS; ARTICLE; CELL ADHESION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

AMINO ACID SUBSTITUTION; ANOIKIS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELL ADHESION; CERAMIDES; CYTOSKELETON; HELA CELLS; HOLOENZYMES; HUMANS; MUTATION, MISSENSE; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; TUMOR SUPPRESSOR PROTEINS;

EID: 77951615510     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.085076     Document Type: Article

References (43)

1. Bialik, S., and Kimchi, A. (2006) Annu. Rev. Biochem. 75, 189-210
2. Zalckvar, E., Berissi, H., Eisenstein, M., and Kimchi, A. (2009) Autophagy 5, 720-722
3. Jin, Y., Blue, E. K., and Gallagher, P. J. (2006) J. Biol. Chem. 281, 39033-39040
4. Kuo, J. C., Wang, W. J., Yao, C. C., Wu, P. R., and Chen, R. H. (2006) J. Cell Biol. 172, 619-631
5. Wang, W. J., Kuo, J. C., Yao, C. C., and Chen, R. H. (2002) J. Cell Biol. 159, 169-179
6. Lin, Y., Stevens, C., and Hupp, T. (2007) J. Biol. Chem. 282, 16792-16802
7. Inbal, B., Cohen, O., Polak-Charcon, S., Kopolovic, J., Vadai, E., Eisenbach, L., and Kimchi, A. (1997) Nature 390, 180-184
8. Raval, A., Tanner, S. M., Byrd, J. C., Angerman, E. B., Perko, J. D., Chen, S. S., Hackanson, B., Grever, M. R., Lucas, D. M., Matkovic, J. J., Lin, T. S., Kipps, T. J., Murray, F., Weisenburger, D., Sanger, W., Lynch, J., Watson, P., Jansen, M., Yoshinaga, Y., Rosenquist, R., de Jong, P. J., Coggill, P., Beck, S., Lynch, H., de la Chapelle, A., and Plass, C. (2007) Cell 129, 879-890
9. Mukhopadhyay, R., Ray, P. S., Arif, A., Brady, A. K., Kinter, M., and Fox, P. L. (2008) Mol. Cell 32, 371-382
10. Zhang, L., Nephew, K. P., and Gallagher, P. J. (2007) J. Biol. Chem. 282, 11795-11804
11. Jin, Y., Blue, E. K., Dixon, S., Shao, Z., and Gallagher, P. J. (2002) J. Biol. Chem. 277, 46980-46986
12. Lin, Y., Stevens, C., Harrison, B., Pathuri, S., Amin, E., and Hupp, T. R. (2009) Mol. Cell. Biochem. 328, 101-107
13. Shohat, G., Spivak-Kroizman, T., Cohen, O., Bialik, S., Shani, G., Berrisi, H., Eisenstein, M., and Kimchi, A. (2001) J. Biol. Chem. 276, 47460-47467
14. Gozuacik, D., Bialik, S., Raveh, T., Mitou, G., Shohat, G., Sabanay, H., Mizushima, N., Yoshimori, T., and Kimchi, A. (2008) Cell Death Differ. 15, 1875-1886
15. Eichhorn, P. J., Creyghton, M. P., and Bernards, R. (2009) Biochim. Biophys. Acta 1795, 1-15
16. Adams, D. G., Coffee, R. L., Jr., Zhang, H., Pelech, S., Strack, S., and Wadzinski, B. E. (2005) J. Biol. Chem. 280, 42644-42654
17. Pelled, D., Raveh, T., Riebeling, C., Fridkin, M., Berissi, H., Futerman, A. H., and Kimchi, A. (2002) J. Biol. Chem. 277, 1957-1961
18. Yamamoto, M., Hioki, T., Ishii, T., Nakajima-Iijima, S., and Uchino, S. (2002) Eur. J. Biochem. 269, 139-147
19. Bialik, S., Bresnick, A. R., and Kimchi, A. (2004) Cell Death Differ. 11, 631-644
20. Strack, S., Chang, D., Zaucha, J. A., Colbran, R. J., and Wadzinski, B. E. (1999) FEBS Lett. 460, 462-466
21. Jin, Y., Blue, E. K., Dixon, S., Hou, L., Wysolmerski, R. B., and Gallagher, P. J. (2001) J. Biol. Chem. 276, 39667-39678
22. Westphal, R. S., Coffee, R. L., Jr., Marotta, A., Pelech, S. L., and Wadzinski, B. E. (1999) J. Biol. Chem. 274, 687-692
23. Zhou, J., Zhang, M., Fang, H., El-Mounayri, O., Rodenberg, J. M., Imbalzano, A. N., and Herring, B. P. (2009) Arterioscler. Thromb. Vasc. Biol. 29, 921-928
24. Adams, D. G., and Wadzinski, B. E. (2007) Methods Mol. Biol. 365, 101-111
25. Ma, J., Arnold, H. K., Lilly, M. B., Sears, R. C., and Kraft, A. S. (2007) Oncogene 26, 5145-5153
26. Goldberg, J., Huang, H. B., Kwon, Y. G., Greengard, P., Nairn, A. C., and Kuriyan, J. (1995) Nature 376, 745-753
27. Yan, L., Lavin, V. A., Moser, L. R., Cui, Q., Kanies, C., and Yang, E. (2008) J. Biol. Chem. 283, 7411-7420
28. Westphal, R. S., Anderson, K. A., Means, A. R., and Wadzinski, B. E. (1998) Science 280, 1258-1261
29. MacKintosh, C., Beattie, K. A., Klumpp, S., Cohen, P., and Codd, G. A. (1990) FEBS Lett. 264, 187-192
30. Cohen, P., and Cohen, P. T. (1989) J. Biol. Chem. 264, 21435-21438
31. Ishihara, H., Martin, B. L., Brautigan, D. L., Karaki, H., Ozaki, H., Kato, Y., Fusetani, N., Watabe, S., Hashimoto, K., Uemura, D., et al. (1989) Biochem. Biophys. Res. Commun. 159, 871-877
32. Swingle, M., Ni, L., and Honkanen, R. E. (2007) Methods Mol. Biol. 365, 23-38
33. Mao, L., Yang, L., Arora, A., Choe, E. S., Zhang, G., Liu, Z., Fibuch, E. E., and Wang, J. Q. (2005) J. Biol. Chem. 280, 12602-12610
34. Neviani, P., Santhanam, R., Oaks, J. J., Eiring, A. M., Notari, M., Blaser, B. W., Liu, S., Trotta, R., Muthusamy, N., Gambacorti-Passerini, C., Druker, B. J., Cortes, J., Marcucci, G., Chen, C. S., Verrills, N. M., Roy, D. C., Caligiuri, M. A., Bloomfield, C. D., Byrd, J. C., and Perrotti, D. (2007) J. Clin. Invest. 117, 2408-2421
35. Dobrowsky, R. T., Kamibayashi, C., Mumby, M. C., and Hannun, Y. A. (1993) J. Biol. Chem. 268, 15523-15530
36. Chalfant, C. E., Szulc, Z., Roddy, P., Bielawska, A., and Hannun, Y. A. (2004) J. Lipid Res. 45, 496-506
37. Hu, W., Xu, R., Zhang, G., Jin, J., Szulc, Z. M., Bielawski, J., Hannun, Y. A., Obeid, L. M., and Mao, C. (2005) Mol. Biol. Cell 16, 1555-1567
38. Cohen, O., Feinstein, E., and Kimchi, A. (1997) EMBO J. 16, 998-1008
39. Chalfant, C. E., Kishikawa, K., Mumby, M. C., Kamibayashi, C., Bielawska, A., and Hannun, Y. A. (1999) J. Biol. Chem. 274, 20313-20317
40. Ruvolo, P. P., Deng, X., Ito, T., Carr, B. K., and May, W. S. (1999) J. Biol. Chem. 274, 20296-20300
41. Frisch, S. M., and Francis, H. (1994) J. Cell Biol. 124, 619-626
42. Liu, Z., Fei, X. W., Fang, Y. J., Shi, W. J., Zhang, Y. Q., and Mei, Y. A. (2008) J. Neurochem. 106, 2463-2475
43. Liu, Z., Xu, J. G., Zhang, H., Fang, Y. J., and Mei, Y. A. (2007) J. Cell. Physiol. 213, 151-160