PLC-dependent intracellular Ca2+ release was associated with C6-ceramide-induced inhibition of Na+ current in rat granule cells

Journal of Neurochemistry

Volumn 106, Issue 6, 2008, Pages 2463-2475

  Liu, Zheng ^a   Fei, Xiao Wei ^a   Fang, Yan Jia ^a   Shi, Wen Jie ^a   Zhang, Yu Qiu ^a   Mei, Yan Ai ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

C6 ceramide; Cell death; Granule cells; Intracellular Ca 2+ release; Na+ current; Ryanodine receptor

Indexed keywords

ACETIC ACID DERIVATIVE; CAFFEINE; CALCIUM CHELATING AGENT; CALCIUM ION; CALMODULIN INHIBITOR; CERAMIDE DERIVATIVE; DANTROLENE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); PHOSPHATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; RYANODINE RECEPTOR;

AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL VIABILITY; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; GRANULE CELL; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SARCOPLASMIC RETICULUM; SODIUM CURRENT; STAINING; STEADY STATE;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CALCIUM SIGNALING; CELL DEATH; CELL MEMBRANE; CELLS, CULTURED; CERAMIDES; CEREBELLAR CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; INTRACELLULAR FLUID; MEMBRANE POTENTIALS; NEURAL INHIBITION; NEURONS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SODIUM CHANNELS; TYPE C PHOSPHOLIPASES;

RATTUS;

EID: 50849108816     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05562.x     Document Type: Article

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