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Volumn 3, Issue 3, 2006, Pages 311-324

Nanoparticle-aptamer bioconjugates for cancer targeting

Author keywords

Aptamer; Cancer therapy; Controlled release; In vitro selection; Nanoparticles; SELEX; Targeted drug delivery

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; APTAMER; CELL PROTEIN; DENILEUKIN DIFTITOX; EPIDERMAL GROWTH FACTOR RECEPTOR 3; LIGAND; NANOPARTICLE; NUCLEIC ACID; NUCLEOLIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; POLYMER; PROSTATE SPECIFIC MEMBRANE ANTIGEN; RITUXIMAB; SIALYL LEWIS X ANTIGEN; T LYMPHOCYTE ANTIGEN; TENASCIN;

EID: 33646851877     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.3.3.311     Document Type: Review
Times cited : (247)

References (111)
  • 1
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: Opportunities and challenges
    • FERRARI M: Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer (2005) 5:161-171.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 2
    • 1842484779 scopus 로고    scopus 로고
    • Designing materials for biology and medicine
    • LANGER R, TIRRELL DA: Designing materials for biology and medicine. Nature (2004) 428:487-492.
    • (2004) Nature , vol.428 , pp. 487-492
    • Langer, R.1    Tirrell, D.A.2
  • 3
    • 8644275490 scopus 로고    scopus 로고
    • A polymer library approach to suicide gene therapy for cancer
    • ANDERSON DG, PENG W, AKINC A et al.: A polymer library approach to suicide gene therapy for cancer. Proc. Natl. Acad. Sci. USA (2004) 101:16028-16033.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16028-16033
    • Anderson, D.G.1    Peng, W.2    Akinc, A.3
  • 4
    • 0025188193 scopus 로고
    • Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
    • SULLENGER BA, GALLARDO HF, UNGERS GE, GILBOA E: Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication. Cell (1990) 63:601-608.
    • (1990) Cell , vol.63 , pp. 601-608
    • Sullenger, B.A.1    Gallardo, H.F.2    Ungers, G.E.3    Gilboa, E.4
  • 5
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • ELLINGTON AD, SZOSTAK JW: In vitro selection of RNA molecules that bind specific ligands. Nature (1990) 346:818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 6
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • TUERK C, GOLD L: Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990) 249:505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 7
    • 0031555233 scopus 로고    scopus 로고
    • FDA approves new kind of lymphoma treatment. Food and Drug Administration
    • JAMES JS, DUBS G: FDA approves new kind of lymphoma treatment. Food and Drug Administration. AIDS Treat. News (1997) 284:2-3.
    • (1997) AIDS Treat. News , vol.284 , pp. 2-3
    • James, J.S.1    Dubs, G.2
  • 8
    • 0034280315 scopus 로고    scopus 로고
    • DAB(389)IL-2 (ONTAK): A novel fusion toxin therapy for lymphoma
    • FOSS FM: DAB(389)IL-2 (ONTAK): a novel fusion toxin therapy for lymphoma. Clin. Lymphoma (2000) 1:110-116.
    • (2000) Clin. Lymphoma , vol.1 , pp. 110-116
    • Foss, F.M.1
  • 9
    • 1642408770 scopus 로고    scopus 로고
    • Selection of internalizing antibodies for drug delivery
    • MARKS JD: Selection of internalizing antibodies for drug delivery. Methods Mol. Biol. (2004) 248:201-208.
    • (2004) Methods Mol. Biol. , vol.248 , pp. 201-208
    • Marks, J.D.1
  • 10
    • 14744301121 scopus 로고
    • Human antibody fragments specific for human blood group antigens from a phage display library
    • MARKS JD, OUWEHAND WH, BYE JM et al: Human antibody fragments specific for human blood group antigens from a phage display library. Biotechnology (1993) 11:1145-1149.
    • (1993) Biotechnology , vol.11 , pp. 1145-1149
    • Marks, J.D.1    Ouwehand, W.H.2    Bye, J.M.3
  • 11
    • 22744446011 scopus 로고    scopus 로고
    • Pegaptanib: The first antiangiogenic agent approved for neovascular macular degeneration
    • DOGGRELL SA: Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration. Expert Opin. Pharmacother. (2005) 6:1421-1423.
    • (2005) Expert Opin. Pharmacother. , vol.6 , pp. 1421-1423
    • Doggrell, S.A.1
  • 12
    • 0033790673 scopus 로고    scopus 로고
    • Escort aptamers: A delivery service for diagnosis and therapy
    • HICKE BJ, STEPHENS AW: Escort aptamers: a delivery service for diagnosis and therapy. J. Clin. Invest. (2000) 106:923-928.
    • (2000) J. Clin. Invest. , vol.106 , pp. 923-928
    • Hicke, B.J.1    Stephens, A.W.2
  • 14
    • 33646833734 scopus 로고    scopus 로고
    • Targeted nanoparticle-aptamer bioconjugates result in significant tumor reduction in vivo
    • In press
    • FAROKHZAD OC, CHENG J, TEPLY BA et al.: Targeted nanoparticle-aptamer bioconjugates result in significant tumor reduction in vivo. Proc. Natl. Acad. Sci. USA (2006). In press.
    • (2006) Proc. Natl. Acad. Sci. USA
    • Farokhzad, O.C.1    Cheng, J.2    Teply, B.A.3
  • 16
    • 0034466813 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
    • DROLET DW, NELSON J, TUCKER CE et al.: Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys. Pharm. Res. (2000) 17:1503-1510.
    • (2000) Pharm. Res. , vol.17 , pp. 1503-1510
    • Drolet, D.W.1    Nelson, J.2    Tucker, C.E.3
  • 17
    • 0034603154 scopus 로고    scopus 로고
    • Adaptive recognition by nucleic acid aptamers
    • HERMANN T, PATEL DJ: Adaptive recognition by nucleic acid aptamers. Science (2000) 287:820-825.
    • (2000) Science , vol.287 , pp. 820-825
    • Hermann, T.1    Patel, D.J.2
  • 18
    • 0032853242 scopus 로고    scopus 로고
    • In vitro selection of functional nucleic acids
    • WILSON DS, SZOSTAK JW: In vitro selection of functional nucleic acids. Ann. Rev. Biochem. (1999) 68:611-647.
    • (1999) Ann. Rev. Biochem. , vol.68 , pp. 611-647
    • Wilson, D.S.1    Szostak, J.W.2
  • 19
    • 0028224199 scopus 로고
    • High-resolution molecular discrimination by RNA
    • JENISON RD, GILL SC, PARDI A, POLISKY B: High-resolution molecular discrimination by RNA. Science (1994) 263:1425-1429.
    • (1994) Science , vol.263 , pp. 1425-1429
    • Jenison, R.D.1    Gill, S.C.2    Pardi, A.3    Polisky, B.4
  • 21
    • 0031279943 scopus 로고    scopus 로고
    • In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase
    • CHARLTON J, SENNELLO J, SMITH D: In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem. Biol. (1997) 4:809-816.
    • (1997) Chem. Biol. , vol.4 , pp. 809-816
    • Charlton, J.1    Sennello, J.2    Smith, D.3
  • 22
    • 0028858581 scopus 로고
    • Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance
    • BEIGELMAN L, MCSWIGGEN JA, DRAPER KG et al.: Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance. J. Biol. Chem. (1995) 270:25702-25708.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25702-25708
    • Beigelman, L.1    Mcswiggen, J.A.2    Draper, K.G.3
  • 23
    • 0026802348 scopus 로고
    • 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase
    • AURUP H, WILLIAMS DM, ECKSTEIN F: 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase. Biochemistry (1992) 31:9636-9641.
    • (1992) Biochemistry , vol.31 , pp. 9636-9641
    • Aurup, H.1    Williams, D.M.2    Eckstein, F.3
  • 24
    • 0026337408 scopus 로고
    • Kinetic characterization of ribonuclease-resistant 2′-modified hammerhead ribozymes
    • PIEKEN WA, OLSEN DB, BENSELER F, AURUP H, ECKSTEIN F: Kinetic characterization of ribonuclease-resistant 2′-modified hammerhead ribozymes. Science (1991) 253:314-317.
    • (1991) Science , vol.53 , pp. 314-317
    • Pieken, W.A.1    Olsen, D.B.2    Benseler, F.3    Aurup, H.4    Eckstein, F.5
  • 25
    • 0142043453 scopus 로고    scopus 로고
    • Spiegelmers: Biostable aptamers
    • EULBERG D, KLUSSMANN S: Spiegelmers: biostable aptamers. Chembiochem. (2003) 4:979-983.
    • (2003) Chembiochem , vol.4 , pp. 979-983
    • Eulberg, D.1    Klussmann, S.2
  • 26
    • 10244257661 scopus 로고    scopus 로고
    • Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
    • SCHMIDT KS, BORKOWSKI S, KURRECK J et al.: Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res. (2004) 32:5757-5765.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5757-5765
    • Schmidt, K.S.1    Borkowski, S.2    Kurreck, J.3
  • 27
    • 25844498391 scopus 로고    scopus 로고
    • Conjugation to polyethylene glycol polymer promotes aptamer biodistribution to healthy and inflamed tissues
    • BOOMER RM, LEWIS SD, HEALY JM, KURZ M, WILSON C, MCCAULEY TG: Conjugation to polyethylene glycol polymer promotes aptamer biodistribution to healthy and inflamed tissues. Oligonucleotides (2005) 15:183-195.
    • (2005) Oligonucleotides , vol.15 , pp. 183-195
    • Boomer, R.M.1    Lewis, S.D.2    Healy, J.M.3    Kurz, M.4    Wilson, C.5    Mccauley, T.G.6
  • 28
    • 17644399512 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of novel aptamer compositions
    • HEALY JM, LEWIS SD, KURZ M et al.: Pharmacokinetics and biodistribution of novel aptamer compositions. Pharm. Res. (2004) 21:2234-2246.
    • (2004) Pharm. Res. , vol.21 , pp. 2234-2246
    • Healy, J.M.1    Lewis, S.D.2    Kurz, M.3
  • 29
    • 0032214640 scopus 로고    scopus 로고
    • Aptamers as ligands in affinity probe capillary electrophoresis
    • GERMAN I, BUCHANAN DD, KENNEDY RT: Aptamers as ligands in affinity probe capillary electrophoresis. Anal. Chem. (1998) 70:4540-4545.
    • (1998) Anal. Chem. , vol.70 , pp. 4540-4545
    • German, I.1    Buchanan, D.D.2    Kennedy, R.T.3
  • 30
    • 0032566763 scopus 로고    scopus 로고
    • Quantum dot bioconjugates for ultrasensitive nonisotopic detection
    • CHAN WC, NIE S: Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science (1998) 281:2016-2018.
    • (1998) Science , vol.281 , pp. 2016-2018
    • Chan, W.C.1    Nie, S.2
  • 31
    • 0038469746 scopus 로고    scopus 로고
    • Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
    • HARISINGHANI MG, BARENTSZ J, HAHN PF et al.: Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N. Engl. J. Med. (2003) 348:2491-2499.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2491-2499
    • Harisinghani, M.G.1    Barentsz, J.2    Hahn, P.F.3
  • 32
    • 0032426610 scopus 로고    scopus 로고
    • Superparamagnetic agents in magnetic resonance imaging: Physicochemical characteristics and clinical applications. A review
    • BONNEMAIN B: Superparamagnetic agents in magnetic resonance imaging: physicochemical characteristics and clinical applications. A review. J. Drug Target. (1998) 6:167-174.
    • (1998) J. Drug Target , vol.6 , pp. 167-174
    • Bonnemain, B.1
  • 33
    • 0036359767 scopus 로고    scopus 로고
    • Scaling down imaging: Molecular mapping of cancer in mice
    • WEISSLEDER R: Scaling down imaging: molecular mapping of cancer in mice. Nat. Rev. Cancer (2002) 2:11-18.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 11-18
    • Weissleder, R.1
  • 34
    • 24744466474 scopus 로고    scopus 로고
    • Aptamers against extracellular targets for in vivo applications
    • PESTOURIE C, TAVITIAN B, DUCONGE F: Aptamers against extracellular targets for in vivo applications. Biochimie (2005) 87:921-930.
    • (2005) Biochimie , vol.87 , pp. 921-930
    • Pestourie, C.1    Tavitian, B.2    Duconge, F.3
  • 35
    • 0041923790 scopus 로고    scopus 로고
    • Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
    • CHEN CH, CHERNIS GA, HOANG VQ, LANDGRAF R: Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proc. Natl. Acad. Sci. USA (2003) 100:9226-9231.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9226-9231
    • Chen, C.H.1    Chernis, G.A.2    Hoang, V.Q.3    Landgraf, R.4
  • 37
    • 0037099536 scopus 로고    scopus 로고
    • Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
    • LUPOLD SE, HICKE BJ, LIN Y, COFFEY DS: Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. (2002) 62:4029-4033.
    • (2002) Cancer Res. , vol.62 , pp. 4029-4033
    • Lupold, S.E.1    Hicke, B.J.2    Lin, Y.3    Coffey, D.S.4
  • 38
    • 0030436735 scopus 로고    scopus 로고
    • Internalization of anti-nucleolin antibody into viable HEp-2 cells
    • DENG JS, BALLOU B, HOFMEISTER JK: Internalization of anti-nucleolin antibody into viable HEp-2 cells. Mol. Biol. Rep. (1996) 23:191-195.
    • (1996) Mol. Biol. Rep. , vol.23 , pp. 191-195
    • Deng, J.S.1    Ballou, B.2    Hofmeister, J.K.3
  • 39
    • 0344304541 scopus 로고    scopus 로고
    • Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
    • CHRISTIAN S, PILCH J, AKERMAN ME, PORKKA K, LAAKKONEN P, RUOSLAHTI E: Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. J. Cell Biol. (2003) 163:871-878.
    • (2003) J. Cell Biol. , vol.163 , pp. 871-878
    • Christian, S.1    Pilch, J.2    Akerman, M.E.3    Porkka, K.4    Laakkonen, P.5    Ruoslahti, E.6
  • 40
    • 0038476179 scopus 로고    scopus 로고
    • Biophysical and biological properties of quadruplex oligodeoxyribonucleotides
    • DAPIC V, ABDOMEROVIC V, MARRINGTON R et al.: Biophysical and biological properties of quadruplex oligodeoxyribonucleotides. Nucleic Acidc Res. (2003) 31:2097-2107.
    • (2003) Nucleic Acidc Res. , vol.31 , pp. 2097-2107
    • Dapic, V.1    Abdomerovic, V.2    Marrington, R.3
  • 41
    • 33646823080 scopus 로고    scopus 로고
    • AGRO100: The translation from lab to clinic of a tumor-targeted nucleic acid aptamer
    • Abstract
    • BARNHART KM, LABER DA, BATES PJ, TRENT JO, MILLER DM; AGRO100: The translation from lab to clinic of a tumor-targeted nucleic acid aptamer. J. Clin. Oncol. (2004) 22(14S):Abstract 3126.
    • (2004) J. Clin. Oncol. , vol.22 , Issue.14 S , pp. 3126
    • Barnhart, K.M.1    Laber, D.A.2    Bates, P.J.3    Trent, J.O.4    Miller, D.M.5
  • 43
    • 0034814741 scopus 로고    scopus 로고
    • In vitro selection of the RNA aptamer against the Sialyl Lewis X and its inhibition of the cell adhesion
    • JEONG S, EOM T, KIM S, LEE S, YU J: In vitro selection of the RNA aptamer against the Sialyl Lewis X and its inhibition of the cell adhesion. Biochem. Biophys. Res. Commun. (2001) 281:237-243.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 237-243
    • Jeong, S.1    Eom, T.2    Kim, S.3    Lee, S.4    Yu, J.5
  • 45
    • 0035966106 scopus 로고    scopus 로고
    • Tenascin-C aptamers are generated using tumor cells and purified protein
    • HICKE BJ, MARION C, CHANG YF et al.: Tenascin-C aptamers are generated using tumor cells and purified protein. J. Biol. Chem. (2001) 276:48644-48654.
    • (2001) J. Biol. Chem. , vol.276 , pp. 48644-48654
    • Hicke, B.J.1    Marion, C.2    Chang, Y.F.3
  • 46
    • 0036790060 scopus 로고    scopus 로고
    • Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
    • PIETRAS K, RUBIN K, SJOBLOM T et al.: Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res. (2002) 62:5476-5484.
    • (2002) Cancer Res. , vol.62 , pp. 5476-5484
    • Pietras, K.1    Rubin, K.2    Sjoblom, T.3
  • 47
    • 0035297541 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
    • PIETRAS K, OSTMAN A, SJOQUIST M et al.: Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res. (2001) 61:2929-2934.
    • (2001) Cancer Res. , vol.61 , pp. 2929-2934
    • Pietras, K.1    Ostman, A.2    Sjoquist, M.3
  • 48
    • 0035844150 scopus 로고    scopus 로고
    • Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen
    • BLANK M, WEINSCHENK T, PRIEMER M, SCHLUESENER H: Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen. J. Biol. Chem. (2001) 276:16464-16468.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3    Schluesener, H.4
  • 50
    • 4444326623 scopus 로고    scopus 로고
    • Evolution of a T7 RNA polymerase variant that transcribes 2′-O-methyl RNA
    • CHELLISERRYKATTIL J, ELLINGTON AD: Evolution of a T7 RNA polymerase variant that transcribes 2′-O-methyl RNA. Nat. Biotechnol. (2004) 22:1155-1160.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1155-1160
    • Chelliserrykattil, J.1    Ellington, A.D.2
  • 51
    • 19944428130 scopus 로고    scopus 로고
    • Direct in vitro selection of a 2′-O-methyl aptamer to VEGF
    • BURMEISTER PE, LEWIS SD, SILVA RF et al.: Direct in vitro selection of a 2′-O-methyl aptamer to VEGF. Chem. Biol. (2005) 12:25-33.
    • (2005) Chem. Biol. , vol.12 , pp. 25-33
    • Burmeister, P.E.1    Lewis, S.D.2    Silva, R.F.3
  • 52
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • LANGER R: Drug delivery and targeting. Nature (1998) 392:5-10.
    • (1998) Nature , vol.392 , pp. 5-10
    • Langer, R.1
  • 54
    • 10744227569 scopus 로고    scopus 로고
    • Large porous particles for pulmonary drug delivery
    • EDWARDS DA, HANES J, CAPONETTI G et al.: Large porous particles for pulmonary drug delivery. Science (1997) 276:1868-1871.
    • (1997) Science , vol.276 , pp. 1868-1871
    • Edwards, D.A.1    Hanes, J.2    Caponetti, G.3
  • 55
    • 0141765877 scopus 로고    scopus 로고
    • Small-scale systems for in vivo drug delivery
    • LAVAN DA, MCGUIRE T, LANGER R: Small-scale systems for in vivo drug delivery. Nat. Biotechnology (2003) 21:1184-1191.
    • (2003) Nat Biotechnology , vol.21 , pp. 1184-1191
    • Lavan, D.A.1    Mcguire, T.2    Langer, R.3
  • 56
    • 0035656898 scopus 로고    scopus 로고
    • Controlled-release of IGF-1 and TGF-β1 in a photopolymerizing hydrogel for cartilage tissue engineering
    • ELISSEEFF J, MCINTOSH W, FU K, BLUNK BT, LANCER R: Controlled-release of IGF-1 and TGF-β1 in a photopolymerizing hydrogel for cartilage tissue engineering. J. Orthop. Res. (2001) 19:1098-1104.
    • (2001) J. Orthop. Res. , vol.19 , pp. 1098-1104
    • Elisseeff, J.1    Mcintosh, W.2    Fu, K.3    Blunk, B.T.4    Lancer, R.5
  • 58
  • 59
    • 0032883731 scopus 로고    scopus 로고
    • New developments in the treatment of Type 1 diabetes mellitus
    • HAAK T: New developments in the treatment of Type 1 diabetes mellitus. Exp. Clin. Endocrinol. Diabetes (1999) 107(Suppl. 3):S108-S113.
    • (1999) Exp. Clin. Endocrinol. Diabetes , vol.107 , Issue.SUPPL. 3
    • Haak, T.1
  • 60
    • 1042291304 scopus 로고    scopus 로고
    • Recent advances in brain tumor therapy: Local intracerebral drug delivery by polymers
    • GUERIN C, OLIVI A, WEINGART JD, LAWSON HC, BREM H: Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest. New Drugs (2004) 22:27-37.
    • (2004) Invest. New Drugs , vol.22 , pp. 27-37
    • Guerin, C.1    Olivi, A.2    Weingart, J.D.3    Lawson, H.C.4    Brem, H.5
  • 61
    • 9244253168 scopus 로고    scopus 로고
    • Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens
    • JIANG W, GUPTA RK, DESHPANDE MC, SCHWENDEMAN SP: Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens. Adv. Drug Deliv. Rev. (2005) 57:391-410.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 391-410
    • Jiang, W.1    Gupta, R.K.2    Deshpande, M.C.3    Schwendeman, S.P.4
  • 62
    • 0037284448 scopus 로고    scopus 로고
    • Treatment outcome of two-stage revision total hip arthroplasty for infected hip arthroplasty using antibiotic-impregnated cement spacer
    • TAKAHIRA N, ITOMAN M, HIGASHI K, UCHIYAMA K, MIYABE M, NARUSE K: Treatment outcome of two-stage revision total hip arthroplasty for infected hip arthroplasty using antibiotic-impregnated cement spacer. J. Orthop. Sci. (2003) 8:26-31.
    • (2003) J. Orthop. Sci. , vol.8 , pp. 26-31
    • Takahira, N.1    Itoman, M.2    Higashi, K.3    Uchiyama, K.4    Miyabe, M.5    Naruse, K.6
  • 63
    • 0035805277 scopus 로고    scopus 로고
    • pH-responsive polymer microspheres: Rapid release of encapsulated material within the range of intracellular pH
    • LYNN DM, AMIJI MM, LANGER R: pH-responsive polymer microspheres: rapid release of encapsulated material within the range of intracellular pH. Angew Chem. Int. Ed. Engl. (2001) 40:1707-1710.
    • (2001) Angew Chem. Int. Ed. Engl. , vol.40 , pp. 1707-1710
    • Lynn, D.M.1    Amiji, M.M.2    Langer, R.3
  • 64
  • 65
    • 0037204998 scopus 로고    scopus 로고
    • Biodegradable, elastic shape-memory polymers for potential biomedical applications
    • LENDLEIN A, LANGER R: Biodegradable, elastic shape-memory polymers for potential biomedical applications. Science (2002) 296: 1673-1676.
    • (2002) Science , vol.296 , pp. 1673-1676
    • Lendlein, A.1    Langer, R.2
  • 66
    • 33646845742 scopus 로고    scopus 로고
    • Glucose responsive nanoparticle for controlled insulin delivery
    • Boston, MA, USA
    • ZION TC, YING JY: Glucose responsive nanoparticle for controlled insulin delivery. Materials Research Society Fall Meeting, Boston, MA, USA (2003).
    • (2003) Materials Research Society Fall Meeting
    • Zion, T.C.1    Ying, J.Y.2
  • 69
    • 3843124278 scopus 로고    scopus 로고
    • Biomimetic polymers in pharmaceutical and biomedical sciences
    • DROTLEFF S, LUNGWITZ U, BREUNIG M et al.: Biomimetic polymers in pharmaceutical and biomedical sciences. Eur. J. Pharm. Biopharm (2004) 58:385-407.
    • (2004) Eur. J. Pharm. Biopharm , vol.58 , pp. 385-407
    • Drotleff, S.1    Lungwitz, U.2    Breunig, M.3
  • 70
    • 14644396096 scopus 로고    scopus 로고
    • Nanomedicine: Current status and future prospects
    • MOGHIMI SM, HUNTER AC, MURRAY JC: Nanomedicine: current status and future prospects. FASEB J. (2005) 19:311-330.
    • (2005) FASEB J. , vol.19 , pp. 311-330
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 71
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • PANYAM J, LABHASETWAR V: Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv. Drug Deliv. Rev. (2003) 55:329-347.
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 73
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • MAEDA H, WU J, SAWA T, MATSUMURA Y, HORI K: Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release (2000) 65:271-284.
    • (2000) J. Control. Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 75
    • 0026567096 scopus 로고
    • Role of liposome size and RES blockade in controlling biodistriburion and tumor uptake of GM1-containing liposomes
    • LIU D, MORI A, HUANG L: Role of liposome size and RES blockade in controlling biodistriburion and tumor uptake of GM1-containing liposomes. Biochim. Biophys. Acta (1992) 1104:95-101.
    • (1992) Biochim. Biophys. Acta , vol.1104 , pp. 95-101
    • Liu, D.1    Mori, A.2    Huang, L.3
  • 76
    • 0028205133 scopus 로고
    • Biodegradable microspheres as controlled-release tetanus toxoid delivery systems
    • ALONSO MJ, GUPTA RK, MIN C, SIBER GR, LANGER R: Biodegradable microspheres as controlled-release tetanus toxoid delivery systems. Vaccine (1994) 12:299-306.
    • (1994) Vaccine , vol.12 , pp. 299-306
    • Alonso, M.J.1    Gupta, R.K.2    Min, C.3    Siber, G.R.4    Langer, R.5
  • 77
    • 0037148662 scopus 로고    scopus 로고
    • Characterization of nanoparticle uptake by endothelial cells
    • DAVDA J, LABHASETWAR V: Characterization of nanoparticle uptake by endothelial cells. Int. J. Pharm. (2002) 233:51-59.
    • (2002) Int. J. Pharm. , vol.233 , pp. 51-59
    • Davda, J.1    Labhasetwar, V.2
  • 78
  • 79
    • 0032850436 scopus 로고    scopus 로고
    • A polycaprolactone nanoparticle formulation of cyclosporin-A improves the prediction of area under the curve using a limited sampling strategy
    • MOLPECERES J, CHACON M, GUZMAN M, BERGES L, DEL ROSARIO ABERTURAS M: A polycaprolactone nanoparticle formulation of cyclosporin-A improves the prediction of area under the curve using a limited sampling strategy. Int. J. Pharm. (1999) 187:101-113.
    • (1999) Int. J. Pharm. , vol.187 , pp. 101-113
    • Molpeceres, J.1    Chacon, M.2    Guzman, M.3    Berges, L.4    Del Rosario Aberturas, M.5
  • 80
  • 81
    • 0031989440 scopus 로고    scopus 로고
    • Surface modification of polyanhydride microspheres
    • GAO J, NIKLASON L, ZHAO XM, LANGER R: Surface modification of polyanhydride microspheres. J. Pharm. Sci. (1998) 87:246-248.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 246-248
    • Gao, J.1    Niklason, L.2    Zhao, X.M.3    Langer, R.4
  • 83
    • 4544227115 scopus 로고    scopus 로고
    • Micropartide formation and its mechanism in single and double emulsion solvent evaporation
    • ROSCA ID, WATARI F, UO M: Micropartide formation and its mechanism in single and double emulsion solvent evaporation. J. Control. Release (2004) 99:271-280.
    • (2004) J. Control. Release , vol.99 , pp. 271-280
    • Rosca, I.D.1    Watari, F.2    Uo, M.3
  • 84
    • 20144367507 scopus 로고    scopus 로고
    • Poly(D,L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency
    • BILATI U, ALLEMANN E, DOELKER E: Poly(D,L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency. J. Microencapsul. (2005) 22:205-214.
    • (2005) J. Microencapsul. , vol.22 , pp. 205-214
    • Bilati, U.1    Allemann, E.2    Doelker, E.3
  • 85
    • 11144228000 scopus 로고    scopus 로고
    • Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles
    • BILATI U, ALLEMANN E, DOELKER E: Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles. Eur J. Pharm. Sci. (2005) 24:67-75.
    • (2005) Eur J. Pharm. Sci. , vol.24 , pp. 67-75
    • Bilati, U.1    Allemann, E.2    Doelker, E.3
  • 86
    • 0037202148 scopus 로고    scopus 로고
    • Lipophilic drug loaded nanospheres prepared by nanoprecipitation: Effect of formulation variables on size, drug recovery and release kinetics
    • CHORNY M, FISHBEIN I, DANENBERG HD, GOLOMB G: Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics. J. Control. Release (2002) 83:389-400.
    • (2002) J. Control. Release , vol.83 , pp. 389-400
    • Chorny, M.1    Fishbein, I.2    Danenberg, H.D.3    Golomb, G.4
  • 87
    • 0035816535 scopus 로고    scopus 로고
    • Drug delivery. Drugs on target
    • LANGER R: Drug delivery. Drugs on target. Science (2001) 293:58-59.
    • (2001) Science , vol.293 , pp. 58-59
    • Langer, R.1
  • 88
    • 0346256860 scopus 로고    scopus 로고
    • Advances in biomaterials, drug delivery, and bionanotechnology
    • LANGER R, PEPPAS NA: Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J. (2003) 49:2990-3006.
    • (2003) AIChE J. , vol.49 , pp. 2990-3006
    • Langer, R.1    Peppas, N.A.2
  • 89
    • 0029120601 scopus 로고
    • Tissue reaction of bioabsorbable ultra high strength poly(L-lactide) rod. A long-term study in rabbits
    • MATSUSUE Y, HANAFUSA S, YAMAMURO T, SHIKINAMI Y, IKADA Y: Tissue reaction of bioabsorbable ultra high strength poly(L-lactide) rod. A long-term study in rabbits. Clin. Orthop. Relat. Res. (1995) 317:246-253.
    • (1995) Clin. Orthop. Relat. Res. , vol.317 , pp. 246-253
    • Matsusue, Y.1    Hanafusa, S.2    Yamamuro, T.3    Shikinami, Y.4    Ikada, Y.5
  • 90
    • 0026052844 scopus 로고
    • The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes
    • CHONN A, CULLIS PR, DEVINE DV: The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes. J. Immunol. (1991) 146:4234-4241.
    • (1991) J. Immunol. , vol.146 , pp. 4234-4241
    • Chonn, A.1    Cullis, P.R.2    Devine, D.V.3
  • 91
    • 0036897324 scopus 로고    scopus 로고
    • Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors
    • CAMPBELL RB, FUKUMURA D, BROWN EB et al.: Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res. (2002) 62:6831-6836.
    • (2002) Cancer Res. , vol.62 , pp. 6831-6836
    • Campbell, R.B.1    Fukumura, D.2    Brown, E.B.3
  • 92
    • 4444289982 scopus 로고    scopus 로고
    • Layer-by-layer surface modification and patterned electrodeposition of quantum dots
    • JAFFAR S, NAM KT, KHADEMHOSSEINI A, XING J, LANGER R, BELCHER AM: Layer-by-layer surface modification and patterned electrodeposition of quantum dots. Nano Lett. (2004) 4:1421-1425.
    • (2004) Nano Lett. , vol.4 , pp. 1421-1425
    • Jaffar, S.1    Nam, K.T.2    Khademhosseini, A.3    Xing, J.4    Langer, R.5    Belcher, A.M.6
  • 93
    • 24644502180 scopus 로고    scopus 로고
    • Microfluidic system for studying the interaction of nanoparticles and microparticles with cells
    • FAROKHZAD OC, KHADEMHOSSEINI A, JON S et al.: Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Anal. Chem. (2005) 77:5453-5459.
    • (2005) Anal. Chem. , vol.77 , pp. 5453-5459
    • Farokhzad, O.C.1    Khademhosseini, A.2    Jon, S.3
  • 94
    • 0030629959 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-coated nanospheres: Potential carriers for intravenous drug administration
    • GREF R, MINAMITAKE Y, PERACCHIA MT et al.: Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration. Pharm. Biotechnol. (1997) 10:167-198.
    • (1997) Pharm. Biotechnol. , vol.10 , pp. 167-198
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 98
    • 24044454384 scopus 로고    scopus 로고
    • Influence of polysaccharide coating on the interactions of nanoparticles with biological systems
    • LEMARCHAND C, GREF R, PASSIRANI C et al.: Influence of polysaccharide coating on the interactions of nanoparticles with biological systems. Biomaterials (2006) 27:108-118.
    • (2006) Biomaterials , vol.27 , pp. 108-118
    • Lemarchand, C.1    Gref, R.2    Passirani, C.3
  • 99
    • 27944496941 scopus 로고    scopus 로고
    • Cell-specific targeting of nanoparticles by multivalent attachment of small molecules
    • WEISSLEDER R, KELLY K, SUN EY, SHTATLAND T, JOSEPHSON L: Cell-specific targeting of nanoparticles by multivalent attachment of small molecules. Nat. Biotechnol (2005) 23:1418-1423.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1418-1423
    • Weissleder, R.1    Kelly, K.2    Sun, E.Y.3    Shtatland, T.4    Josephson, L.5
  • 100
    • 0034781649 scopus 로고    scopus 로고
    • Biodistribution of long-circulating PEG-grafted nanocapsules in mice: Effects of PEG chain length and density
    • MOSQUEIRA VC, LEGRAND P, MORGAT JL et al.: Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density. Pharm. Res. (2001) 18:1411-1419.
    • (2001) Pharm. Res. , vol.18 , pp. 1411-1419
    • Mosqueira, V.C.1    Legrand, P.2    Morgat, J.L.3
  • 103
    • 0028281399 scopus 로고
    • A method for the high efficiency of water-soluble carbodiimide-mediated amidation
    • SEHGAL D, VIJAY IK: A method for the high efficiency of water-soluble carbodiimide-mediated amidation. Anal. Biochem. (1994) 218:87-91.
    • (1994) Anal. Biochem. , vol.218 , pp. 87-91
    • Sehgal, D.1    Vijay, I.K.2
  • 104
    • 16444363225 scopus 로고    scopus 로고
    • Ligand density effect on biorecognition by pegylated gold nanoparticles: Regulated interaction of RCA(120) lectin with lactose installed to the distal end of tethered PEG strands on gold surface
    • TAKAE S, AKIYAMA Y, OTSUKA H, NAKAMURA T, NAGASAKI Y, KATAOKA K: Ligand density effect on biorecognition by pegylated gold nanoparticles: regulated interaction of RCA(120) lectin with lactose installed to the distal end of tethered PEG strands on gold surface. Biomacromolecules (2005) 6:818-824.
    • (2005) Biomacromolecules , vol.6 , pp. 818-824
    • Takae, S.1    Akiyama, Y.2    Otsuka, H.3    Nakamura, T.4    Nagasaki, Y.5    Kataoka, K.6
  • 105
    • 4444379133 scopus 로고    scopus 로고
    • Nanoparticle and targeted systems for cancer therapy
    • BRANNON-PEPPAS L, BLANCHETTE JO: Nanoparticle and targeted systems for cancer therapy. Adv. Drug Del. Rev. (2004) 56:1649-1659.
    • (2004) Adv. Drug Del. Rev. , vol.56 , pp. 1649-1659
    • Brannon-peppas, L.1    Blanchette, J.O.2
  • 106
    • 0033567094 scopus 로고    scopus 로고
    • Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor
    • MONSKY WL, FUKUMURA D, GOHONGI T et al.: Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res. (1999) 59:4129-4135.
    • (1999) Cancer Res. , vol.59 , pp. 4129-4135
    • Monsky, W.L.1    Fukumura, D.2    Gohongi, T.3
  • 107
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • MAEDA H: The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. (2001) 41:189-207.
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 189-207
    • Maeda, H.1
  • 108
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
    • YUAN F, DELLIAN M, FUKUMURA D et al.: Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. (1995) 55:3752-3756.
    • (1995) Cancer Res. , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3
  • 109
    • 0034662609 scopus 로고    scopus 로고
    • Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
    • KONG G, BRAUN RD, DEWHIRST MW: Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res. (2000) 60:4440-4445.
    • (2000) Cancer Res. , vol.60 , pp. 4440-4445
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 110
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • YUAN F, LEUNIG M, HUANG SK, BERK DA, PAPAHADJOPOULOS D, JAIN RK: Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res. (1994) 54:3352-3356.
    • (1994) Cancer Res. , vol.54 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 111
    • 0025869933 scopus 로고
    • Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism
    • BAXTER LT, JAIN RK: Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism. Microvasc. Res. (1991) 41:5-23.
    • (1991) Microvasc. Res. , vol.41 , pp. 5-23
    • Baxter, L.T.1    Jain, R.K.2


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