Binding conformations and QSAR of CA-4 analogs as tubulin inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 3, 2010, Pages 421-429

  Liao, Si Yan ^a   Chen, Jin Can ^a,b   Miao, Ti Fang ^a   Shen, Yong ^a   Zheng, Kang Cheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Combretastatin A4; Docking; Inhibition mechanism; QSAR; Tubulin

Indexed keywords

COMBRETASTATIN A4; COMBRETASTATIN A4 DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CATALYTIC DOMAIN; COMPUTER SIMULATION; CYTOTOXINS; HUMANS; MOLECULAR CONFORMATION; PROTEIN BINDING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STILBENES; TUBULIN MODULATORS;

EID: 77951483638     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360903213499     Document Type: Article

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