QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa

European Journal of Medicinal Chemistry

Volumn 43, Issue 10, 2008, Pages 2159-2170

  Liao, Si Yan ^a   Chen, Jin Can ^a   Qian, Li ^a   Shen, Yong ^a   Zheng, Kang Cheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cytotoxicity; DFT calculation; Flavone derivative; Molecular design; QSAR

Indexed keywords

FLAVONE DERIVATIVE; ISOFLAVONE DERIVATIVE;

ARTICLE; CORRELATION COEFFICIENT; DENSITY FUNCTIONAL THEORY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; ENERGY; GROWTH INHIBITION; HELA CELL; MOLECULAR MECHANICS; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM CHEMISTRY; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CYTOTOXINS; DNA; DRUG DESIGN; FLAVONOIDS; HELA CELLS; HUMANS; ISOFLAVONES; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUANTUM THEORY;

EID: 53149137110     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.10.033     Document Type: Article

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