Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: Comparative studies using CYP2E1-null and wild-type mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 305, Issue 2, 2003, Pages 557-564

  Hoffler, Undi ^a,c   El Masri, Hisham A ^b   Ghanayem, Burhan I ^a,c  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOBENZOTRIAZOLE; CARBON DIOXIDE; CYTOCHROME P450 2E1; ESTERASE; LIVER EXTRACT; PARAOXON; URETHAN;

ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; DRUG HALF LIFE; ENZYME INHIBITION; ENZYME METABOLISM; FEMALE; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; WILD TYPE;

ANIMALS; CARBON DIOXIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTER SIMULATION; CYTOCHROME P-450 CYP2E1; FECES; HALF-LIFE; LIVER; MALE; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PARAOXON; TISSUE DISTRIBUTION; TRIAZOLES; URETHANE;

EID: 0344921333     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.049072     Document Type: Article

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