Long-term vitamin A supplementation at therapeutic doses induces mitochondrial electrons transfer chain (METC) impairment and increased mitochondrial membrane-enriched fraction (MMEF) 3-nitrotyrosine on rat heart

Free Radical Research

Volumn 44, Issue 5, 2010, Pages 505-512

  Da Rocha, Ricardo F ^a   De Oliveira, Marcos Roberto ^a   Schonhofen, Patrícia ^a   Schnorr, Carlos Eduardo ^a   Dal Pizzol, Felipe ^b   Moreira, José Cláudio F ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Myocardio; Nitrosative stress; Oxidative stress; Respiratory chain; Retinol

Indexed keywords

3 NITROTYROSINE; CATALASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; RETINOL PALMITATE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOVASCULAR SYSTEM; CHEMOLUMINESCENCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MITOCHONDRION; LIPID OXIDATION; LONG TERM CARE; MALE; MITOCHONDRIAL RESPIRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RAT; VITAMIN SUPPLEMENTATION;

ANIMALS; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEART; MALE; MITOCHONDRIA, HEART; MYOCARDIUM; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; TIME FACTORS; TYROSINE; VITAMIN A;

RATTUS;

EID: 77951266419     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715761003636849     Document Type: Article

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