Immune changes in post-menopausal osteoporosis: The Immunos study

Osteoporosis International

Volumn 21, Issue 5, 2010, Pages 805-814

  Breuil, V ^a,b   Ticchioni, M ^a,c   Testa, J ^d   Roux, C H ^a   Ferrari, P ^e   Breittmayer, J P ^c   Albert Sabonnadiere C ^a   Durant, J ^a   De Perreti, F ^e   Bernard, A ^a,c   Euller Ziegler, L ^a   Carle, G F ^b  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c INSERM   (France)

^d UNIVERSITY HOSPITAL OF NICE   (France)

^e University Hospital of Nice University of Nice Sophia Antipolis   (France)

Author keywords

B lymphocytes; Body composition; Cytokines; Osteoimmunology; Osteoporosis; T lymphocyte

Indexed keywords

CD19 ANTIGEN; CD27 ANTIGEN; CD28 ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD45RA ANTIGEN; CD5 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; BODY COMPOSITION; BODY MASS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ESTRADIOL BLOOD LEVEL; FEMALE; FRAGILITY FRACTURE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; MEMORY CELL; MUSCLE ATROPHY; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; B-LYMPHOCYTE SUBSETS; BODY COMPOSITION; CASE-CONTROL STUDIES; DENDRITIC CELLS; ESTROGENS; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNITY, CELLULAR; IMMUNOPHENOTYPING; INTERFERON-GAMMA; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; OSTEOPOROTIC FRACTURES; PILOT PROJECTS; T-LYMPHOCYTE SUBSETS;

EID: 77951254310     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-009-1018-7     Document Type: Article

References (42)

1. O Johnell JA Kanis 2006 An estimate of the worldwide prevalence and disability associated with osteoporotic fractures Osteoporos Int. 17 1726 33 10.1007/s00198-006-0172-4 1:STN:280:DC%2BD28nitVSksQ%3D%3D 16983459 (Pubitemid 44607392)
2. DM Kado WS Browner L Palermo, et al. 1999 Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group Arch Intern Med. 159 1215 20 10.1001/archinte.159.11.1215 1:STN:280:DyaK1M3pslKguw%3D%3D 10371229 (Pubitemid 29269861)
3. J Lorenzo M Horowitz Y Choi 2008 Osteoimmunology: interactions of the bone and immune system Endocr. Rev. 29 403 40 10.1210/er.2007-0038 1:CAS:528:DC%2BD1cXosVCqu7o%3D 18451259 (Pubitemid 351831507)
4. H Takayanagi K Sato A Takaoka, et al. 2005 Interplay between interferon and other cytokine systems in bone metabolism Immunol Rev 208 181 193 10.1111/j.0105-2896.2005.00337.x 1:CAS:528:DC%2BD28Xks1eiuw%3D%3D 16313349 (Pubitemid 41746393)
5. GR Mundy 2007 Osteoporosis and inflammation Nutr. Rev. 65 S147 51 10.1111/j.1753-4887.2007.tb00353.x 18240539
6. N Horwood 2008 Lymphocyte-derived cytokines in inflammatory arthritis Autoimmunity. 41 230 8 10.1080/08916930701694766 1:CAS:528:DC%2BD1cXjs12ktb4%3D 18365837 (Pubitemid 351454994)
7. YY Kong U Feige I Sarosi, et al. 1999 Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand Nature 402 304 9 10.1038/46303 1:CAS:528:DyaK1MXnvFShsLg%3D 10580503
8. K Briot P Garnero A Le Henanff, et al. 2005 Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor alpha treatment Ann Rheum Dis. 64 1137 40 10.1136/ard.2004.028670 1:CAS:528:DC%2BD2MXpslGmsro%3D 15642695 (Pubitemid 41113346)
9. S Visvanathan D van der Heijde A Deodhar, et al. 2008 Effects of infliximab on markers of inflammation and bone turnover and associations with bone mineral density in patients with ankylosing spondylitis Ann Rheum Dis. 68 175 82 10.1136/ard.2007.084426 18495735
10. JA Lorenzo A Naprta Y Rao, et al. 1998 Mice lacking the type I interleukin-1 receptor do not lose bone mass after ovariectomy Endocrinology. 139 3022 5 10.1210/en.139.6.3022 1:CAS:528:DyaK1cXjsFSks7g%3D 9607815 (Pubitemid 28512417)
11. V Poli R Balena E Fattori, et al. 1994 Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion EMBO J. 13 1189 96 1:CAS:528:DyaK2cXitFGjt74%3D 8131749 (Pubitemid 24074725)
12. S Cenci MN Weitzmann C Roggia, et al. 2000 Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha J Clin Invest. 106 1229 37 10.1172/JCI11066 1:CAS:528:DC%2BD3cXotlChu78%3D 11086024
13. C Blin-Wakkach A Wakkach N Rochet, et al. 2004 Characterization of a novel bipotent hematopoietic progenitor population in normal and osteopetrotic mice J Bone Miner Res 19 1137 43 10.1359/JBMR.040318 15176997 (Pubitemid 41110566)
14. Y Li A Li X Yang, et al. 2007 Ovariectomy-induced bone loss occurs independently of B cells J Cell Biochem. 100 1370 5 10.1002/jcb.21121 1:CAS:528:DC%2BD2sXjvVSlsbc%3D 17131364 (Pubitemid 46515571)
15. World Health Organization (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO Technical Report Series. WHO, Geneva
16. MJ Delmonico TB Harris JS Lee, et al. 2007 Health, Aging and Body Composition Study.Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women J Am Geriatr Soc 55 769 74 10.1111/j.1532-5415.2007.01140.x 17493199 (Pubitemid 46668965)
17. NE Lane 2006 Epidemiology, etiology, and diagnosis of osteoporosis Am J Obstet Gynecol. 194 S3 11 10.1016/j.ajog.2005.08.047 1:CAS:528: DC%2BD28XhtVamtLk%3D 16448873 (Pubitemid 43152482)
18. P Ravn G Cizza NH Bjarnason, et al. 1999 Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women. Early Postmenopausal Intervention Cohort (EPIC) study group J Bone Miner Res 14 1622 7 10.1359/jbmr.1999.14.9.1622 1:STN:280:DyaK1Mzpslyksw%3D%3D 10469292 (Pubitemid 29416690)
19. G Martini R Valenti S Giovani, et al. 1997 Age-related changes in body composition of healthy and osteoporotic women Maturitas. 27 25 33 10.1016/S0378-5122(97)01108-0 1:STN:280:DyaK2szgtFKksQ%3D%3D 9158074 (Pubitemid 27230294)
20. AM Schott C Cormier D Hans, et al. 1998 How hip and whole-body bone mineral density predict hip fracture in elderly women: the EPIDOS Prospective Study Osteoporos Int. 8 247 54 10.1007/s001980050061 1:STN:280: DyaK1M%2FhsVKnsQ%3D%3D 9797909 (Pubitemid 28427074)
21. S Gnudi E Sitta N Fiumi 2007 Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass J Bone Miner Metab. 25 326 32 10.1007/s00774-007-0758-8 17704998 (Pubitemid 47283263)
22. C Joseph AM Kenny P Taxel, et al. 2005 Role of endocrine-immune dysregulation in osteoporosis, sarcopenia, frailty and fracture risk Mol Aspects Med. 26 181 201 10.1016/j.mam.2005.01.004 1:CAS:528:DC%2BD2MXjtlWjsLo%3D 15811434 (Pubitemid 40462026)
23. MC Walsh GR Hunter MB Livingstone 2006 Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density Osteoporos Int. 17 61 7 10.1007/s00198-005-1900-x 15995793 (Pubitemid 41798029)
24. L Rodríguez J Graniel R Ortiz 2007 Effect of leptin on activation and cytokine synthesis in peripheral blood lymphocytes of malnourished infected children Clin Exp Immunol 148 478 85 17355247 (Pubitemid 46701024)
25. P Sansoni R Vescovini F Fagnoni, et al. 2008 The immune system in extreme longevity Exp Gerontol. 43 61 5 10.1016/j.exger.2007.06.008 1:CAS:528:DC%2BD1cXptlGmsw%3D%3D 17870272
26. FT Hakim FA Flomerfelt M Boyiadzis, et al. 2004 Aging, immunity and cancer Curr Opin Immunol 16 151 6 10.1016/j.coi.2004.01.009 1:CAS:528: DC%2BD2cXitFKksrY%3D 15023406 (Pubitemid 38328716)
27. L Lazuardi B Jenewein AM Wolf, et al. 2005 Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes Immunology 114 37 43 10.1111/j.1365-2567.2004.02006.x 1:CAS:528: DC%2BD2MXlt1KrtQ%3D%3D 15606793 (Pubitemid 40030291)
28. MN Weitzmann R Pacifici 2006 Estrogen regulation of immune cell bone interactions Ann N Y Acad Sci. 1068 256 74 10.1196/annals.1346.030 1:CAS:528:DC%2BD28XntFenuro%3D 16831927 (Pubitemid 43824158)
29. P D'Amelio A Grimaldi S Di Bella, et al. 2008 Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: a key mechanism in osteoporosis Bone. 43 92 100 10.1016/j.bone.2008.02.017 18407820
30. MT Cantorna S Yu D Bruce 2008 The paradoxical effects of vitamin D on type 1 mediated immunity Mol Aspects Med. 29 369 75 10.1016/j.mam.2008.04.004 1:CAS:528:DC%2BD1cXhtlyiur3J 18561994
31. Y Gao F Grassi MR Ryan, et al. 2007 IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation J Clin Invest. 117 122 32 10.1172/JCI30074 1:CAS:528:DC%2BD2sXmvV2qtg%3D%3D 17173138 (Pubitemid 46048459)
32. SX Zheng Y Vrindts M Lopez, et al. 1997 Increase in cytokine production (IL-1 beta, IL-6, TNF-alpha but not IFN-gamma, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis Maturitas 26 63 71 10.1016/S0378-5122(96)01080-8 1:CAS:528:DyaK2sXhsVGku7s%3D 9032749 (Pubitemid 27063783)
33. P Pietschmann J Grisar R Thien, et al. 2001 Immune phenotype and intracellular cytokine production of peripheral blood mononuclear cells from postmenopausal patients with osteoporotic fractures Exp Gerontol. 36 1749 59 10.1016/S0531-5565(01)00125-5 1:CAS:528:DC%2BD3MXnslWqur0%3D 11672994 (Pubitemid 32982878)
34. MC Walsh N Kim Y Kadono, et al. 2006 Osteoimmunology: interplay between the immune system and bone metabolism Annu Rev Immunol. 24 33 63 10.1146/annurev.immunol.24.021605.090646 1:CAS:528:DC%2BD28XkvFSqt74%3D 16551243
35. P Mezquita-Raya M De La Higuera DF Garcia, et al. 2005 The contribution of serum osteoprotegerin to bone mass and vertebral fractures in postmenopausal women Osteoporos Int. 16 1368 1374 10.1007/s00198-005-1844-1 15711777 (Pubitemid 41532089)
36. A Stern GA Laughlin J Bergstrom, et al. 2007 The sex-specific association of serum osteoprotegerin and receptor activator of nuclear factor kappaB legend with bone mineral density in older adults: the Rancho Bernardo study Eur J Endocrinol. 156 555 62 10.1530/EJE-06-0753 1:CAS:528:DC%2BD2sXls1ynsbw%3D 17468191 (Pubitemid 46796522)
37. H Uemura T Yasui Y Miyatani, et al. 2008 Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand in post-menopausal women J Endocrinol Invest. 31 163 8 1:CAS:528: DC%2BD1cXmt1emsbs%3D 18362509 (Pubitemid 351596978)
38. Y Imai T Tsunenari M Fukase, et al. 1990 Quantitative bone histomorphometry and circulating T lymphocyte subsets in postmenopausal osteoporosis J Bone Miner Res. 5 393 9 10.1002/jbmr.5650050413 1:STN:280:DyaK3c3mtFGgug%3D%3D 2343779 (Pubitemid 20276840)
39. E Montecino-Rodriguez K Dorshkind 2006 Evolving patterns of lymphopoiesis from embryogenesis through senescence Immunity 24 659 662 10.1016/j.immuni. 2006.06.001 1:CAS:528:DC%2BD28Xms1Crtrc%3D 16782019 (Pubitemid 43867370)
40. G Eghbali-Fatourechi S Khosla A Sanyal, et al. 2003 Role of RANK ligand in mediating increased bone resorption in early postmenopausal women J. Clin. Invest. 111 1221 1230 1:CAS:528:DC%2BD3sXjtFCrs7g%3D 12697741 (Pubitemid 36519939)
41. BF Boyce L Xing 2008 Bruton and Tec: new links in osteoimmunology Cell Metab 7 283 5 10.1016/j.cmet.2008.03.013 1:CAS:528:DC%2BD1cXkvV2is74%3D 18396132 (Pubitemid 351455223)
42. JY Wu DT Scadden HM Kronenberg 2009 Role of the osteoblast lineage in the bone marrow hematopoietic niches J Bone Miner Res 24 759 64 10.1359/jbmr.090225 19257832